Click here to switch to the map view.

The map label for this gene is spkB [H]

Identifier: 148241221

GI number: 148241221

Start: 117231

End: 119204

Strand: Direct

Name: spkB [H]

Synonym: SynRCC307_0122

Alternate gene names: 148241221

Gene position: 117231-119204 (Clockwise)

Preceding gene: 148241220

Following gene: 148241223

Centisome position: 5.27

GC content: 63.27

Gene sequence:

>1974_bases
GTGGCCGTGCCGACCCCTGCTGAGGCCGCCAGCGGAGCCTTGCTTGAGCGCCGTTATCGCCTCGATGAGGTTCTCAGCGA
GGCTGAGGGCACGCGCCTCTGGCGCGGCGCCGACACGTTGGTGGGTGAGTTGCCCGTGGCCATTCGCGCCTGGTGGGGGC
TCACGGATGAAGAGTTAGCGGCCTTGCAGCAGCGCTTGGAGCGGCTCAAGGCCGTGCTGCATCCCCAAATTCCCCGCTTG
GGGGAGCAGTTGCCTGCCGAGGGTGGTTGCTGGCAGGTCCGCGAATGGATTAGTGGGCGCACCTACCAAGACCTGCTGCA
GGCCCGCCAAGAGCGGCAGCTTGTCTTTGGCTCTGGGGAGGTGCTGCTGCTGCTGCGGCAGTTGCTGCCTGCCTTAGCTG
CTTTGCATGGGCAGAACCTGGTGCATGGCGATCTGACCCCCGCCAATTTGGTTCGCCGCGATAGCGATGGACTGCCGGTG
CTGATTGATTTCGGCCTGCAAGCTGCCGTCGTTGGTCAACCGCTGACTGCTGCCACGGCGGGCTATGCCCCACCCCAGGC
CAGGCACGAGCCCTATGGGCTGTGGATGGACCTCTACAGCCTCGGTGTTGTGGCCCTCGTGCTGCTTAGTGGTGAAGAGC
CAGCAGCCTTAATGGATCCCGTGTCGCTGGCCTGGCGCTGGCCGGAAGGGATTGATCTGGATGCTGCGTTTCGCCAGGTG
CTGGAGCGGCTGCTGGCAACAAGCCCTGAGCAGCGCTTCAACTCAGCGGCTGAGGTGGCTGAGGCGTTAACCGCTCTGCC
TGTCCCTGAGAGCACCGGGCCGGTGAGCCGCTCGGATCGCACGGCTGTGTTGCTGCCGCAGCTCAAGCCAGAGCAGCAAG
CAGAGGCATCTCCTGCCCCTGCGCCCACCCGTCCAACCCGCGATGAGCGCCGGCGCGCCAAAGAACAAGCCGCGGAAGGT
CGTTTTTGGCCTGTGGTGATTGCCCTGCTCTTGGCAGCGTTGGTGGGTTCGGCTTTGGGTTGGTTGCTGTTGGGTCGCAA
CCGCCAGAGCAACCGCCCGGCTTCAGCGCTTGCACCGGAGCTCAGCTTGCCGCCAGCCGAGTTGGATCAACGCCAGCAAT
TGCTTAATCGCCTCAGGGCGTTGCAGGTCGATCAGGCCTGGTTTCTCAAGTTGGTGGATAGCAGCCTCGCGGCTCAGTTC
CCGGAGCGAGGCGGGCGAGCACCCACCGACTCCTTGGAGGATGCGCCCCTGCGCAAAATCTGGAACGACCTAGCCCAGGA
GTGGCTGGTGCGCGTTGAGCAGCTTCCTGTTCCCCTGCGCCAACGCCTGGGCAGTTACACAGATGCGGATTGGAAGCAAC
GCGAGAAATCCCTCACCAAAGAGGGTCTGAGTCCATTGGTGCTGCGGCAGTTGGTCAGCAGCAGCGCTCAGAACCTGCTG
CCCGGCCGCAATCCAGAGACGATTCCTGCTGAGCCTGTGCGGCAGATCTGGTATGCCGCAGCTCTGCGCAGCTTGGAAGG
CCTCAAGGTGGAGCAGCTCAAGCCTGTTTTGAACGTCCCGAGTTCACTAAGCACGTCAGTGGATGGGCAAGGGGCCAAGT
TGATCGCCATCAACGTGCCCAAAAACCATCGTTTGGTGCTGGGGGTCAATGGCACGCCGTTGATGCAGATGAGCTTGTTT
GCCGCCAATGGCAAGGTGCTGGAGCCCCGTGGTCCGCTGCGGGTGCTCAGCGTGGCCCGGGTGGAGAACTCCCCGGTGCA
GTTGTTGATTCGCAACGATGGCCTCGCTCCAGGCTTAATCAGCCTTTCGGTGCGGGTTGATCCGCCCTTGCCCAAGCCTG
CGCGCGAGACCCAACGGCCTCGCCAACAGCAGCCTTCCGCTCAGCCGCCCAACCAGCCTCAGCCCCAAACTCCGAAGCAG
GATTCGGTGCTTGATGAGATCAAGCAGCCCACGGTTGATCCCTTTGGCAATTAG

Upstream 100 bases:

>100_bases
GCTATCGCTCCCGCATTTGGAATCAGGAGTGGTTGCAAAGCCGGGGGCTGCGCCAGCCAGAGCGGCAGCAACTCGGTAGC
GTCGCTTAAGAGCCAGAAGA

Downstream 100 bases:

>100_bases
AGGCGTTTGAGGGCGGAGCGCAGATCCTTCTGGTCTTGCTTGCGGCGCTCTTCCTGGCGTTTGTCATGAAGCTTCCGGCC
TTTGCCCAGGCCGATGGTGA

Product: serine/threonine protein kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 657; Mature: 656

Protein sequence:

>657_residues
MAVPTPAEAASGALLERRYRLDEVLSEAEGTRLWRGADTLVGELPVAIRAWWGLTDEELAALQQRLERLKAVLHPQIPRL
GEQLPAEGGCWQVREWISGRTYQDLLQARQERQLVFGSGEVLLLLRQLLPALAALHGQNLVHGDLTPANLVRRDSDGLPV
LIDFGLQAAVVGQPLTAATAGYAPPQARHEPYGLWMDLYSLGVVALVLLSGEEPAALMDPVSLAWRWPEGIDLDAAFRQV
LERLLATSPEQRFNSAAEVAEALTALPVPESTGPVSRSDRTAVLLPQLKPEQQAEASPAPAPTRPTRDERRRAKEQAAEG
RFWPVVIALLLAALVGSALGWLLLGRNRQSNRPASALAPELSLPPAELDQRQQLLNRLRALQVDQAWFLKLVDSSLAAQF
PERGGRAPTDSLEDAPLRKIWNDLAQEWLVRVEQLPVPLRQRLGSYTDADWKQREKSLTKEGLSPLVLRQLVSSSAQNLL
PGRNPETIPAEPVRQIWYAAALRSLEGLKVEQLKPVLNVPSSLSTSVDGQGAKLIAINVPKNHRLVLGVNGTPLMQMSLF
AANGKVLEPRGPLRVLSVARVENSPVQLLIRNDGLAPGLISLSVRVDPPLPKPARETQRPRQQQPSAQPPNQPQPQTPKQ
DSVLDEIKQPTVDPFGN

Sequences:

>Translated_657_residues
MAVPTPAEAASGALLERRYRLDEVLSEAEGTRLWRGADTLVGELPVAIRAWWGLTDEELAALQQRLERLKAVLHPQIPRL
GEQLPAEGGCWQVREWISGRTYQDLLQARQERQLVFGSGEVLLLLRQLLPALAALHGQNLVHGDLTPANLVRRDSDGLPV
LIDFGLQAAVVGQPLTAATAGYAPPQARHEPYGLWMDLYSLGVVALVLLSGEEPAALMDPVSLAWRWPEGIDLDAAFRQV
LERLLATSPEQRFNSAAEVAEALTALPVPESTGPVSRSDRTAVLLPQLKPEQQAEASPAPAPTRPTRDERRRAKEQAAEG
RFWPVVIALLLAALVGSALGWLLLGRNRQSNRPASALAPELSLPPAELDQRQQLLNRLRALQVDQAWFLKLVDSSLAAQF
PERGGRAPTDSLEDAPLRKIWNDLAQEWLVRVEQLPVPLRQRLGSYTDADWKQREKSLTKEGLSPLVLRQLVSSSAQNLL
PGRNPETIPAEPVRQIWYAAALRSLEGLKVEQLKPVLNVPSSLSTSVDGQGAKLIAINVPKNHRLVLGVNGTPLMQMSLF
AANGKVLEPRGPLRVLSVARVENSPVQLLIRNDGLAPGLISLSVRVDPPLPKPARETQRPRQQQPSAQPPNQPQPQTPKQ
DSVLDEIKQPTVDPFGN
>Mature_656_residues
AVPTPAEAASGALLERRYRLDEVLSEAEGTRLWRGADTLVGELPVAIRAWWGLTDEELAALQQRLERLKAVLHPQIPRLG
EQLPAEGGCWQVREWISGRTYQDLLQARQERQLVFGSGEVLLLLRQLLPALAALHGQNLVHGDLTPANLVRRDSDGLPVL
IDFGLQAAVVGQPLTAATAGYAPPQARHEPYGLWMDLYSLGVVALVLLSGEEPAALMDPVSLAWRWPEGIDLDAAFRQVL
ERLLATSPEQRFNSAAEVAEALTALPVPESTGPVSRSDRTAVLLPQLKPEQQAEASPAPAPTRPTRDERRRAKEQAAEGR
FWPVVIALLLAALVGSALGWLLLGRNRQSNRPASALAPELSLPPAELDQRQQLLNRLRALQVDQAWFLKLVDSSLAAQFP
ERGGRAPTDSLEDAPLRKIWNDLAQEWLVRVEQLPVPLRQRLGSYTDADWKQREKSLTKEGLSPLVLRQLVSSSAQNLLP
GRNPETIPAEPVRQIWYAAALRSLEGLKVEQLKPVLNVPSSLSTSVDGQGAKLIAINVPKNHRLVLGVNGTPLMQMSLFA
ANGKVLEPRGPLRVLSVARVENSPVQLLIRNDGLAPGLISLSVRVDPPLPKPARETQRPRQQQPSAQPPNQPQPQTPKQD
SVLDEIKQPTVDPFGN

Specific function: Protein kinase required for cell motility, but not for phototaxis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI217330634, Length=326, Percent_Identity=25.1533742331288, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI26667203, Length=164, Percent_Identity=31.0975609756098, Blast_Score=71, Evalue=4e-12,
Organism=Homo sapiens, GI26667199, Length=164, Percent_Identity=31.0975609756098, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI26667211, Length=164, Percent_Identity=31.0975609756098, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI26667196, Length=164, Percent_Identity=31.0975609756098, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI26667191, Length=164, Percent_Identity=31.0975609756098, Blast_Score=70, Evalue=7e-12,
Organism=Homo sapiens, GI25952114, Length=164, Percent_Identity=31.7073170731707, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI25952118, Length=163, Percent_Identity=31.2883435582822, Blast_Score=67, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17539480, Length=209, Percent_Identity=26.3157894736842, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24653974, Length=209, Percent_Identity=25.3588516746411, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24653972, Length=209, Percent_Identity=25.3588516746411, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24653970, Length=209, Percent_Identity=25.3588516746411, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24653968, Length=209, Percent_Identity=25.3588516746411, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001646
- InterPro:   IPR020636
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017441
- InterPro:   IPR017442
- InterPro:   IPR016252 [H]

Pfam domain/function: PF00805 Pentapeptide; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 72024; Mature: 71893

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVPTPAEAASGALLERRYRLDEVLSEAEGTRLWRGADTLVGELPVAIRAWWGLTDEELA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHCCHHHHHHCCCCHHHHH
ALQQRLERLKAVLHPQIPRLGEQLPAEGGCWQVREWISGRTYQDLLQARQERQLVFGSGE
HHHHHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCEEECCCH
VLLLLRQLLPALAALHGQNLVHGDLTPANLVRRDSDGLPVLIDFGLQAAVVGQPLTAATA
HHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHCCCCCCEEEEECCCHHHHHCCCHHHHHC
GYAPPQARHEPYGLWMDLYSLGVVALVLLSGEEPAALMDPVSLAWRWPEGIDLDAAFRQV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHEEECCCCCCHHHHHHHH
LERLLATSPEQRFNSAAEVAEALTALPVPESTGPVSRSDRTAVLLPQLKPEQQAEASPAP
HHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCHHHHCCCCCC
APTRPTRDERRRAKEQAAEGRFWPVVIALLLAALVGSALGWLLLGRNRQSNRPASALAPE
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCC
LSLPPAELDQRQQLLNRLRALQVDQAWFLKLVDSSLAAQFPERGGRAPTDSLEDAPLRKI
CCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
WNDLAQEWLVRVEQLPVPLRQRLGSYTDADWKQREKSLTKEGLSPLVLRQLVSSSAQNLL
HHHHHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
PGRNPETIPAEPVRQIWYAAALRSLEGLKVEQLKPVLNVPSSLSTSVDGQGAKLIAINVP
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHCCCCCCCCCEEEEEECC
KNHRLVLGVNGTPLMQMSLFAANGKVLEPRGPLRVLSVARVENSPVQLLIRNDGLAPGLI
CCCEEEEECCCCCHHHHEEEECCCCEECCCCCHHHHHHHHCCCCCEEEEEECCCCCCCEE
SLSVRVDPPLPKPARETQRPRQQQPSAQPPNQPQPQTPKQDSVLDEIKQPTVDPFGN
EEEEEECCCCCCCCHHHCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
AVPTPAEAASGALLERRYRLDEVLSEAEGTRLWRGADTLVGELPVAIRAWWGLTDEELA
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHCCHHHHHHCCCCHHHHH
ALQQRLERLKAVLHPQIPRLGEQLPAEGGCWQVREWISGRTYQDLLQARQERQLVFGSGE
HHHHHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCEEECCCH
VLLLLRQLLPALAALHGQNLVHGDLTPANLVRRDSDGLPVLIDFGLQAAVVGQPLTAATA
HHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHCCCCCCEEEEECCCHHHHHCCCHHHHHC
GYAPPQARHEPYGLWMDLYSLGVVALVLLSGEEPAALMDPVSLAWRWPEGIDLDAAFRQV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHEEECCCCCCHHHHHHHH
LERLLATSPEQRFNSAAEVAEALTALPVPESTGPVSRSDRTAVLLPQLKPEQQAEASPAP
HHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCHHHHCCCCCC
APTRPTRDERRRAKEQAAEGRFWPVVIALLLAALVGSALGWLLLGRNRQSNRPASALAPE
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCC
LSLPPAELDQRQQLLNRLRALQVDQAWFLKLVDSSLAAQFPERGGRAPTDSLEDAPLRKI
CCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
WNDLAQEWLVRVEQLPVPLRQRLGSYTDADWKQREKSLTKEGLSPLVLRQLVSSSAQNLL
HHHHHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
PGRNPETIPAEPVRQIWYAAALRSLEGLKVEQLKPVLNVPSSLSTSVDGQGAKLIAINVP
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHCCCCCCCCCEEEEEECC
KNHRLVLGVNGTPLMQMSLFAANGKVLEPRGPLRVLSVARVENSPVQLLIRNDGLAPGLI
CCCEEEEECCCCCHHHHEEEECCCCEECCCCCHHHHHHHHCCCCCEEEEEECCCCCCCEE
SLSVRVDPPLPKPARETQRPRQQQPSAQPPNQPQPQTPKQDSVLDEIKQPTVDPFGN
EEEEEECCCCCCCCHHHCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12732981; 8905231 [H]