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The map label for this gene is lysS

Identifier: 148241213

GI number: 148241213

Start: 110673

End: 112181

Strand: Direct

Name: lysS

Synonym: SynRCC307_0114

Alternate gene names: 148241213

Gene position: 110673-112181 (Clockwise)

Preceding gene: 148241212

Following gene: 148241214

Centisome position: 4.97

GC content: 60.04

Gene sequence:

>1509_bases
GTGAGCGAGCTGCGAGATACCCGCCTGGAGAAAGCCCAGGCATTAATTGAATGCGGCCAAGTGCCGTATGCCCTGCGTTT
TGAGCCAAGCCATCGCACCGCTGAGCTGCAGCAAGCTCACGCCGATCTGCCCAATGGCGAAGAGCGTGATGTCTCCGTTG
CGATCGCTGGCCGCGTGATGACGCGCCGGGTCATGGGCAAGTTGGCGTTTTTCACCCTCGCTGATGAGACCGGCCCCATT
CAGCTGTTTTTGGAAAAAGCCGCGCTGGGAGATGCGTTTAAGCAGATCACCAGCCTGGTGGATGCCGGCGACTGGATCGG
GGTCAAGGGCACCTTGCGCCGCACCGATCGCGGTGAGTTGTCGGTGAAGGCAGCGCAATGGCAGATGCTCAGCAAAAGCC
TGCAGCCGCTACCGGACAAATGGCATGGCCTGGCTGATGTGGAGAAGCGCTACCGCCAGCGCTACCTCGATCTGATCGTT
TCTCCCGATACCCGCGACACCTTCCGCCGCCGCGCGCAGCTGGTGAGCGGCATCCGCCGCTGGCTGGATGAGCGCGATTT
CCTGGAGATTGAAACCCCTGTGCTGCAAAGCGAGCCCGGAGGCGCCGATGCCCGGCCCTTTGAAACGCACCACAACGCCC
TGGATCTGCCGTTAACGCTGCGCATTGCGACCGAGCTCCACCTCAAGCGCTTGGTGGTGGGTGGTTTTGAGCGGGTCTAT
GAGCTGGGCCGGATTTTCAGAAATGAGGGCGTCAGCACGCGCCACAACCCTGAATTCACCTCAGTGGAGATCTATCAAGC
CTTCGCTGATTACAACGACATGATGGATCTCACCGAGGAGCTGATCAGCTCGGTGACCCAGCAGGTTTGCGGCAGCACCT
TGATCAACTACCAAGGCACCGAGATCAATTTGGCCCCGGGCTGGCGCCGGGCCACCATGCATGAACTGGTGAAAGAAGCG
ACTGGGCTTGATTTCGCCGGCTTCAGTAGCCGCGAAGATGCTGCCGCAGCCATGGAAGCCAAGGGGTTGCAGACCCCGGC
CTTGGCGGATTCGGTGGGCCGTTTGCTCAATGAGGCCTTTGAGCAGGCCGTGGAAGAAACCCTGATTCAGCCCACCTTCG
TTACTGACTATCCCGTTGAGATTTCACCGTTGGCGCGGTCCCACCGCAGCAAGCCAGGGTTGGTGGAGCGTTTTGAGCTG
TTCATCGTCGGCCGTGAGCATGGCAATGCCTTCAGTGAGCTGACTGATCCAGTGGATCAGCGTCAACGCCTCGAGGCGCA
GCAAGAGCGGCGTGCAGCAGGTGATCTAGAGGCGCAGCGCGTTGATGAGGACTTTTTGAATGCCCTTGAGGTGGGCATGC
CACCCACCGGTGGTTTGGGCATTGGCATTGATCGCCTGGTGATGCTGCTCACCGATAGCCCATCGATCCGTGATGTGATC
GCGTTTCCGCTGCTAAAGCCGGAAAGCCGAGACGGGTCCGCCGCAGTGGATAATGGTTCCACTGAGTAG

Upstream 100 bases:

>100_bases
TCGAGCCGGATCCCCGCAATCCTGAATTGATCCTCACGGTGCGGGGCACGGGTTATGCCTCTCAGCGTCTCGGCGAACTC
AGCGCAGCCGGAGCCTGAGC

Downstream 100 bases:

>100_bases
ATTTCCTCTGGCATGAGTGGAGAGCGCGTCGGTTTTCGTTTCACCCACGCCGATGCTGTGGTGAAGCGCAATCCCCAGGG
CCGGTCACGCCGGGGTTGGG

Product: lysyl-tRNA synthetase

Products: NA

Alternate protein names: Lysine--tRNA ligase; LysRS

Number of amino acids: Translated: 502; Mature: 501

Protein sequence:

>502_residues
MSELRDTRLEKAQALIECGQVPYALRFEPSHRTAELQQAHADLPNGEERDVSVAIAGRVMTRRVMGKLAFFTLADETGPI
QLFLEKAALGDAFKQITSLVDAGDWIGVKGTLRRTDRGELSVKAAQWQMLSKSLQPLPDKWHGLADVEKRYRQRYLDLIV
SPDTRDTFRRRAQLVSGIRRWLDERDFLEIETPVLQSEPGGADARPFETHHNALDLPLTLRIATELHLKRLVVGGFERVY
ELGRIFRNEGVSTRHNPEFTSVEIYQAFADYNDMMDLTEELISSVTQQVCGSTLINYQGTEINLAPGWRRATMHELVKEA
TGLDFAGFSSREDAAAAMEAKGLQTPALADSVGRLLNEAFEQAVEETLIQPTFVTDYPVEISPLARSHRSKPGLVERFEL
FIVGREHGNAFSELTDPVDQRQRLEAQQERRAAGDLEAQRVDEDFLNALEVGMPPTGGLGIGIDRLVMLLTDSPSIRDVI
AFPLLKPESRDGSAAVDNGSTE

Sequences:

>Translated_502_residues
MSELRDTRLEKAQALIECGQVPYALRFEPSHRTAELQQAHADLPNGEERDVSVAIAGRVMTRRVMGKLAFFTLADETGPI
QLFLEKAALGDAFKQITSLVDAGDWIGVKGTLRRTDRGELSVKAAQWQMLSKSLQPLPDKWHGLADVEKRYRQRYLDLIV
SPDTRDTFRRRAQLVSGIRRWLDERDFLEIETPVLQSEPGGADARPFETHHNALDLPLTLRIATELHLKRLVVGGFERVY
ELGRIFRNEGVSTRHNPEFTSVEIYQAFADYNDMMDLTEELISSVTQQVCGSTLINYQGTEINLAPGWRRATMHELVKEA
TGLDFAGFSSREDAAAAMEAKGLQTPALADSVGRLLNEAFEQAVEETLIQPTFVTDYPVEISPLARSHRSKPGLVERFEL
FIVGREHGNAFSELTDPVDQRQRLEAQQERRAAGDLEAQRVDEDFLNALEVGMPPTGGLGIGIDRLVMLLTDSPSIRDVI
AFPLLKPESRDGSAAVDNGSTE
>Mature_501_residues
SELRDTRLEKAQALIECGQVPYALRFEPSHRTAELQQAHADLPNGEERDVSVAIAGRVMTRRVMGKLAFFTLADETGPIQ
LFLEKAALGDAFKQITSLVDAGDWIGVKGTLRRTDRGELSVKAAQWQMLSKSLQPLPDKWHGLADVEKRYRQRYLDLIVS
PDTRDTFRRRAQLVSGIRRWLDERDFLEIETPVLQSEPGGADARPFETHHNALDLPLTLRIATELHLKRLVVGGFERVYE
LGRIFRNEGVSTRHNPEFTSVEIYQAFADYNDMMDLTEELISSVTQQVCGSTLINYQGTEINLAPGWRRATMHELVKEAT
GLDFAGFSSREDAAAAMEAKGLQTPALADSVGRLLNEAFEQAVEETLIQPTFVTDYPVEISPLARSHRSKPGLVERFELF
IVGREHGNAFSELTDPVDQRQRLEAQQERRAAGDLEAQRVDEDFLNALEVGMPPTGGLGIGIDRLVMLLTDSPSIRDVIA
FPLLKPESRDGSAAVDNGSTE

Specific function: Unknown

COG id: COG1190

COG function: function code J; Lysyl-tRNA synthetase (class II)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI5031815, Length=494, Percent_Identity=42.1052631578947, Blast_Score=392, Evalue=1e-109,
Organism=Homo sapiens, GI194272210, Length=495, Percent_Identity=42.020202020202, Blast_Score=390, Evalue=1e-108,
Organism=Homo sapiens, GI40789249, Length=268, Percent_Identity=26.4925373134328, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1789256, Length=493, Percent_Identity=48.4787018255578, Blast_Score=455, Evalue=1e-129,
Organism=Escherichia coli, GI1790571, Length=495, Percent_Identity=48.2828282828283, Blast_Score=454, Evalue=1e-129,
Organism=Escherichia coli, GI87082379, Length=320, Percent_Identity=32.8125, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1788173, Length=257, Percent_Identity=28.7937743190661, Blast_Score=94, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17535925, Length=507, Percent_Identity=41.025641025641, Blast_Score=376, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI17535927, Length=507, Percent_Identity=41.025641025641, Blast_Score=376, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI71994340, Length=502, Percent_Identity=41.2350597609562, Blast_Score=375, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI17551876, Length=468, Percent_Identity=22.8632478632479, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI32566633, Length=238, Percent_Identity=28.9915966386555, Blast_Score=79, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6320242, Length=512, Percent_Identity=41.796875, Blast_Score=383, Evalue=1e-107,
Organism=Saccharomyces cerevisiae, GI6324256, Length=493, Percent_Identity=29.6146044624746, Blast_Score=183, Evalue=5e-47,
Organism=Saccharomyces cerevisiae, GI6323011, Length=484, Percent_Identity=23.7603305785124, Blast_Score=91, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6325153, Length=241, Percent_Identity=26.9709543568465, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24640849, Length=492, Percent_Identity=44.1056910569106, Blast_Score=389, Evalue=1e-108,
Organism=Drosophila melanogaster, GI24640851, Length=492, Percent_Identity=44.1056910569106, Blast_Score=388, Evalue=1e-108,

Paralogues:

None

Copy number: 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYK_SYNR3 (A5GQ58)

Other databases:

- EMBL:   CT978603
- RefSeq:   YP_001226370.1
- ProteinModelPortal:   A5GQ58
- SMR:   A5GQ58
- STRING:   A5GQ58
- GeneID:   5156699
- GenomeReviews:   CT978603_GR
- KEGG:   syr:SynRCC307_0114
- eggNOG:   COG1190
- HOGENOM:   HBG631383
- OMA:   ANEESRH
- ProtClustDB:   PRK00484
- GO:   GO:0005737
- HAMAP:   MF_00252
- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR002313
- InterPro:   IPR018149
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR22594
- PANTHER:   PTHR22594:SF4
- PRINTS:   PR00982
- TIGRFAMs:   TIGR00499

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB

EC number: =6.1.1.6

Molecular weight: Translated: 56064; Mature: 55933

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELRDTRLEKAQALIECGQVPYALRFEPSHRTAELQQAHADLPNGEERDVSVAIAGRVM
CCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCEEEEHHHHHH
TRRVMGKLAFFTLADETGPIQLFLEKAALGDAFKQITSLVDAGDWIGVKGTLRRTDRGEL
HHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCE
SVKAAQWQMLSKSLQPLPDKWHGLADVEKRYRQRYLDLIVSPDTRDTFRRRAQLVSGIRR
EEHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
WLDERDFLEIETPVLQSEPGGADARPFETHHNALDLPLTLRIATELHLKRLVVGGFERVY
HHCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
ELGRIFRNEGVSTRHNPEFTSVEIYQAFADYNDMMDLTEELISSVTQQVCGSTLINYQGT
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EINLAPGWRRATMHELVKEATGLDFAGFSSREDAAAAMEAKGLQTPALADSVGRLLNEAF
EEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHH
EQAVEETLIQPTFVTDYPVEISPLARSHRSKPGLVERFELFIVGREHGNAFSELTDPVDQ
HHHHHHHHCCCCEECCCCCCCCHHHHHCCCCCCHHEEEEEEEEECCCCCHHHHHCCHHHH
RQRLEAQQERRAAGDLEAQRVDEDFLNALEVGMPPTGGLGIGIDRLVMLLTDSPSIRDVI
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCHHHHH
AFPLLKPESRDGSAAVDNGSTE
HHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SELRDTRLEKAQALIECGQVPYALRFEPSHRTAELQQAHADLPNGEERDVSVAIAGRVM
CCHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCEEEEHHHHHH
TRRVMGKLAFFTLADETGPIQLFLEKAALGDAFKQITSLVDAGDWIGVKGTLRRTDRGEL
HHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCE
SVKAAQWQMLSKSLQPLPDKWHGLADVEKRYRQRYLDLIVSPDTRDTFRRRAQLVSGIRR
EEHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
WLDERDFLEIETPVLQSEPGGADARPFETHHNALDLPLTLRIATELHLKRLVVGGFERVY
HHCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
ELGRIFRNEGVSTRHNPEFTSVEIYQAFADYNDMMDLTEELISSVTQQVCGSTLINYQGT
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EINLAPGWRRATMHELVKEATGLDFAGFSSREDAAAAMEAKGLQTPALADSVGRLLNEAF
EEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHH
EQAVEETLIQPTFVTDYPVEISPLARSHRSKPGLVERFELFIVGREHGNAFSELTDPVDQ
HHHHHHHHCCCCEECCCCCCCCHHHHHCCCCCCHHEEEEEEEEECCCCCHHHHHCCHHHH
RQRLEAQQERRAAGDLEAQRVDEDFLNALEVGMPPTGGLGIGIDRLVMLLTDSPSIRDVI
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCHHHHH
AFPLLKPESRDGSAAVDNGSTE
HHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA