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The map label for this gene is yycF [H]

Identifier: 148241212

GI number: 148241212

Start: 109897

End: 110670

Strand: Direct

Name: yycF [H]

Synonym: SynRCC307_0113

Alternate gene names: 148241212

Gene position: 109897-110670 (Clockwise)

Preceding gene: 148241211

Following gene: 148241213

Centisome position: 4.94

GC content: 60.72

Gene sequence:

>774_bases
ATGCAATCGGGAGAGTCCACTCCCAATCAGCCGACCGCCACGCTGTTGGTGGTCGACGATGAGCCGGCAGTGCGTCGCGT
CCTTTCGATGCGTCTGCAGCTCTCGGGTTATCGGGTGGTGTGCGCTGAAGACGGCGAGCAAGCGCTCGAGCTCTTTGCCA
GTGAGCAGCCGGATTTAGTGGTGCTCGACGTAATGATGCCGAAGCTCGATGGCTTTGCGGTGTGCCGCAGGCTTCGCGCT
GAATCGGCTGTGCCGATCGTTTTCCTCTCTTCTCTTGATGCCATCGCCGAAAAGGTGGCTGGTTTGGATCTCGGCGCTGA
CGATTACCTCTCCAAACCCTTCAGTCCTAAAGAACTTGAGGCGCGAATTAGTCGGATTCTGGGTCGTGTTGTTGGCCGCG
GCACAGCGAGCCAAGATCCCCGCGAGCCCGTGGCTGGCCTAGGTGTGCTTCGCCTTGGCGATTTGGTGGTGGACACCAAT
CGCCGCCAAGTGAGCCGTGGTGGCGAACGTATTTCACTCACCTACACCGAATTCAGTTTGCTGGAGCTTCTGTTCCGTGA
ACCGGGCCGGGTGGTGCCTCGCGCGGAGATCCTTGAGCAGCTGTGGGGTTACCCTCCCAGACGCACAGCTGATCTACGCG
TCGTGGATGTGTATGTGGCCCGCCTGCGGGGCAAGCTCGAGCCGGATCCCCGCAATCCTGAATTGATCCTCACGGTGCGG
GGCACGGGTTATGCCTCTCAGCGTCTCGGCGAACTCAGCGCAGCCGGAGCCTGA

Upstream 100 bases:

>100_bases
CGAAAGACTTGTGCGTTGCTGCACCGCTGCACCTGCTTTTTGCGCTCGGTCAGGGTCTGCGCATCTGTAGGGTTGCATCT
CGTAAATATTCCGCTCGCTG

Downstream 100 bases:

>100_bases
GCGTGAGCGAGCTGCGAGATACCCGCCTGGAGAAAGCCCAGGCATTAATTGAATGCGGCCAAGTGCCGTATGCCCTGCGT
TTTGAGCCAAGCCATCGCAC

Product: two-component system response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MQSGESTPNQPTATLLVVDDEPAVRRVLSMRLQLSGYRVVCAEDGEQALELFASEQPDLVVLDVMMPKLDGFAVCRRLRA
ESAVPIVFLSSLDAIAEKVAGLDLGADDYLSKPFSPKELEARISRILGRVVGRGTASQDPREPVAGLGVLRLGDLVVDTN
RRQVSRGGERISLTYTEFSLLELLFREPGRVVPRAEILEQLWGYPPRRTADLRVVDVYVARLRGKLEPDPRNPELILTVR
GTGYASQRLGELSAAGA

Sequences:

>Translated_257_residues
MQSGESTPNQPTATLLVVDDEPAVRRVLSMRLQLSGYRVVCAEDGEQALELFASEQPDLVVLDVMMPKLDGFAVCRRLRA
ESAVPIVFLSSLDAIAEKVAGLDLGADDYLSKPFSPKELEARISRILGRVVGRGTASQDPREPVAGLGVLRLGDLVVDTN
RRQVSRGGERISLTYTEFSLLELLFREPGRVVPRAEILEQLWGYPPRRTADLRVVDVYVARLRGKLEPDPRNPELILTVR
GTGYASQRLGELSAAGA
>Mature_257_residues
MQSGESTPNQPTATLLVVDDEPAVRRVLSMRLQLSGYRVVCAEDGEQALELFASEQPDLVVLDVMMPKLDGFAVCRRLRA
ESAVPIVFLSSLDAIAEKVAGLDLGADDYLSKPFSPKELEARISRILGRVVGRGTASQDPREPVAGLGVLRLGDLVVDTN
RRQVSRGGERISLTYTEFSLLELLFREPGRVVPRAEILEQLWGYPPRRTADLRVVDVYVARLRGKLEPDPRNPELILTVR
GTGYASQRLGELSAAGA

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786784, Length=231, Percent_Identity=40.2597402597403, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI1786911, Length=232, Percent_Identity=38.7931034482759, Blast_Score=151, Evalue=4e-38,
Organism=Escherichia coli, GI1786599, Length=233, Percent_Identity=36.0515021459227, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1790863, Length=237, Percent_Identity=32.9113924050633, Blast_Score=137, Evalue=6e-34,
Organism=Escherichia coli, GI1788394, Length=237, Percent_Identity=35.0210970464135, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1789809, Length=236, Percent_Identity=35.5932203389831, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI87082012, Length=231, Percent_Identity=34.1991341991342, Blast_Score=130, Evalue=9e-32,
Organism=Escherichia coli, GI1790860, Length=235, Percent_Identity=35.7446808510638, Blast_Score=127, Evalue=5e-31,
Organism=Escherichia coli, GI1787375, Length=232, Percent_Identity=34.9137931034483, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=36.7965367965368, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1789402, Length=238, Percent_Identity=35.7142857142857, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=31.4655172413793, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI1790552, Length=234, Percent_Identity=33.3333333333333, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI145693140, Length=232, Percent_Identity=33.6206896551724, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1788550, Length=114, Percent_Identity=38.5964912280702, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1790437, Length=130, Percent_Identity=33.8461538461538, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790299, Length=129, Percent_Identity=30.2325581395349, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788713, Length=128, Percent_Identity=35.15625, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI145693157, Length=102, Percent_Identity=36.2745098039216, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1787487, Length=100, Percent_Identity=33, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 28178; Mature: 28178

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSGESTPNQPTATLLVVDDEPAVRRVLSMRLQLSGYRVVCAEDGEQALELFASEQPDLV
CCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHCCCCCEE
VLDVMMPKLDGFAVCRRLRAESAVPIVFLSSLDAIAEKVAGLDLGADDYLSKPFSPKELE
EEEEHHCCCCHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHH
ARISRILGRVVGRGTASQDPREPVAGLGVLRLGDLVVDTNRRQVSRGGERISLTYTEFSL
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCEEEECCHHHHHCCCCEEEEEEHHHHH
LELLFREPGRVVPRAEILEQLWGYPPRRTADLRVVDVYVARLRGKLEPDPRNPELILTVR
HHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEE
GTGYASQRLGELSAAGA
CCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MQSGESTPNQPTATLLVVDDEPAVRRVLSMRLQLSGYRVVCAEDGEQALELFASEQPDLV
CCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHCCCCCEE
VLDVMMPKLDGFAVCRRLRAESAVPIVFLSSLDAIAEKVAGLDLGADDYLSKPFSPKELE
EEEEHHCCCCHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHH
ARISRILGRVVGRGTASQDPREPVAGLGVLRLGDLVVDTNRRQVSRGGERISLTYTEFSL
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCEEEECCHHHHHCCCCEEEEEEHHHHH
LELLFREPGRVVPRAEILEQLWGYPPRRTADLRVVDVYVARLRGKLEPDPRNPELILTVR
HHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEE
GTGYASQRLGELSAAGA
CCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]