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The map label for this gene is ptsG [H]

Identifier: 147675620

GI number: 147675620

Start: 1719739

End: 1721241

Strand: Reverse

Name: ptsG [H]

Synonym: VC0395_A1599

Alternate gene names: 147675620

Gene position: 1721241-1719739 (Counterclockwise)

Preceding gene: 147674791

Following gene: 147675350

Centisome position: 56.92

GC content: 47.77

Gene sequence:

>1503_bases
GTGCTAACATTTAGGCTACGGGGGTATGCCGTTAGTCCCAGCAATTCTAATAACTTAATCAGGAGCATAAACATGTTTAA
GAACGCTTTTGCGAATCTGCAAAAGGTCGGTAAGGCGCTGATGCTGCCAGTATCAGTTTTGCCTGTCGCCGGTATTTTGC
TAGGCGTGGGTGCCGCTAATTTTAGCTGGCTACCAGAAGTGGTATCACATCTCATGGAACAGGCGGGTGGTTCAGTCTTT
GGTCAAATGCCATTGCTATTTGCGGTCGGTGTTGCCCTAGGCTTTACTAACAACGACGGTGTATCTGGTCTGTCTGCTAT
CGTCGGTTACGGCATTATGGTTGCGACTTTAAAAGTCATGGCAACTGTGATGGGTGTGAGCGGCATCGATACTGGTGTTC
TGGGTGGTATCCTAGCCGGTGGTGTTGCAGCTTGGTCATTCAACCGTTTCTACAAAATTCAACTGCCTGAATATCTGGGT
TTCTTTGCAGGTAAACGTGCTGTTCCAATCATCACGGGTTTTATTTCGATTGCACTGGGTGTGGTTCTGTCATTCATTTG
GCCACCAATCGGTTCTGCGATCGCCACTTTCTCTGACTGGGCGGCAAACCAAGATCCTGTAACCGCATTTGGTATCTACG
GTATCGTTGAGCGTTCACTGATCCCATTTGGTCTGCATCATATTTGGAACGTACCTTTCTTCTACCAAGCTGGTACTTGT
GTGAATGGTGCGGGTGAAACCGTTAACGGCATCATGACTTGCTTCCTAACGGCTGACGATGCTTCTCGTGCGGCAGGCAA
TGGCTTCGGTCAATTGGCAGGTGGCTATTTGTTCAAAATGTTCGGTCTTCCAGCCGCTGCATTTGCTATCGCTCACTGTG
CTAAGCCTGAAAACCGTGCAAAAGTAATGGGTATCATGGCTTCTGCTGCTCTGACTTCATTCCTAACCGGTATTACTGAG
CCAATCGAATTCGCATTCTTGTTCGTAGCTCCAGTACTGTACGCTATCCACGCTGTATTAGCAGGTCTGGCTTACGTTCT
GACTAACGCGCTGGGCGTGGTTCACGGTCATACCTTCTCTAACGGTTTCATTGACTTTGTTGTTCAATCACCACGTGCAG
ATAACATGTTACTGCTGGTTGGCTTAGGCATTGGCTACGCTGTGCTGTACTACGTAGTATTCACATTCGTTATCCGTGCT
CTTAACCTAAAAACACCAGGTCGTGAAGACGAGAGCGCTGATAAATCGGCATCAAGCGGTAATGAGCTGGCTGGTGATCT
GGTTGCCGCATTCGGTGGTAAAGCGAACATTACTAACCTAGATGCGTGTATCACTCGTTTGCGTGTATCGGTAGCCGATA
CTGCTCTGGTTGATCAGGATAAGCTGAAAAAGCTTGGTGCAGCAGGTGTGGTTATGGTTTCTGGTGGTGTACAAGCTATC
TTCGGTACTAAATCAGACAACCTGAAAACTGAAATGGATGAGTGGATCCGTAACAACGGTTAA

Upstream 100 bases:

>100_bases
TTTGAAACTTAATTTCGTCGCAAACTAGAAAATTTGAGGGGTATCAAGATATATTTAGAGCCGGAAAATATAATGCAAAA
AGTGGTTACATTTTCACTGG

Downstream 100 bases:

>100_bases
TCTCATTCTTCCCCCTAGAGAAAAGGAGACCTTAGGTCTCCTTTTTTATGTTTTGAGGAATCTGCCATTGATCCACAGAT
TCCTCGTCGTTCTGTATCCG

Product: PTS system glucose-specific transporter subunits IIBC

Products: NA

Alternate protein names: EIICB-Glc; EII-Glc; Glucose permease IIC component; PTS system glucose-specific EIIC component; Glucose-specific phosphotransferase enzyme IIB component; PTS system glucose-specific EIIB component [H]

Number of amino acids: Translated: 500; Mature: 500

Protein sequence:

>500_residues
MLTFRLRGYAVSPSNSNNLIRSINMFKNAFANLQKVGKALMLPVSVLPVAGILLGVGAANFSWLPEVVSHLMEQAGGSVF
GQMPLLFAVGVALGFTNNDGVSGLSAIVGYGIMVATLKVMATVMGVSGIDTGVLGGILAGGVAAWSFNRFYKIQLPEYLG
FFAGKRAVPIITGFISIALGVVLSFIWPPIGSAIATFSDWAANQDPVTAFGIYGIVERSLIPFGLHHIWNVPFFYQAGTC
VNGAGETVNGIMTCFLTADDASRAAGNGFGQLAGGYLFKMFGLPAAAFAIAHCAKPENRAKVMGIMASAALTSFLTGITE
PIEFAFLFVAPVLYAIHAVLAGLAYVLTNALGVVHGHTFSNGFIDFVVQSPRADNMLLLVGLGIGYAVLYYVVFTFVIRA
LNLKTPGREDESADKSASSGNELAGDLVAAFGGKANITNLDACITRLRVSVADTALVDQDKLKKLGAAGVVMVSGGVQAI
FGTKSDNLKTEMDEWIRNNG

Sequences:

>Translated_500_residues
MLTFRLRGYAVSPSNSNNLIRSINMFKNAFANLQKVGKALMLPVSVLPVAGILLGVGAANFSWLPEVVSHLMEQAGGSVF
GQMPLLFAVGVALGFTNNDGVSGLSAIVGYGIMVATLKVMATVMGVSGIDTGVLGGILAGGVAAWSFNRFYKIQLPEYLG
FFAGKRAVPIITGFISIALGVVLSFIWPPIGSAIATFSDWAANQDPVTAFGIYGIVERSLIPFGLHHIWNVPFFYQAGTC
VNGAGETVNGIMTCFLTADDASRAAGNGFGQLAGGYLFKMFGLPAAAFAIAHCAKPENRAKVMGIMASAALTSFLTGITE
PIEFAFLFVAPVLYAIHAVLAGLAYVLTNALGVVHGHTFSNGFIDFVVQSPRADNMLLLVGLGIGYAVLYYVVFTFVIRA
LNLKTPGREDESADKSASSGNELAGDLVAAFGGKANITNLDACITRLRVSVADTALVDQDKLKKLGAAGVVMVSGGVQAI
FGTKSDNLKTEMDEWIRNNG
>Mature_500_residues
MLTFRLRGYAVSPSNSNNLIRSINMFKNAFANLQKVGKALMLPVSVLPVAGILLGVGAANFSWLPEVVSHLMEQAGGSVF
GQMPLLFAVGVALGFTNNDGVSGLSAIVGYGIMVATLKVMATVMGVSGIDTGVLGGILAGGVAAWSFNRFYKIQLPEYLG
FFAGKRAVPIITGFISIALGVVLSFIWPPIGSAIATFSDWAANQDPVTAFGIYGIVERSLIPFGLHHIWNVPFFYQAGTC
VNGAGETVNGIMTCFLTADDASRAAGNGFGQLAGGYLFKMFGLPAAAFAIAHCAKPENRAKVMGIMASAALTSFLTGITE
PIEFAFLFVAPVLYAIHAVLAGLAYVLTNALGVVHGHTFSNGFIDFVVQSPRADNMLLLVGLGIGYAVLYYVVFTFVIRA
LNLKTPGREDESADKSASSGNELAGDLVAAFGGKANITNLDACITRLRVSVADTALVDQDKLKKLGAAGVVMVSGGVQAI
FGTKSDNLKTEMDEWIRNNG

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787343, Length=484, Percent_Identity=66.5289256198347, Blast_Score=639, Evalue=0.0,
Organism=Escherichia coli, GI1786894, Length=480, Percent_Identity=38.75, Blast_Score=284, Evalue=1e-77,
Organism=Escherichia coli, GI1787908, Length=513, Percent_Identity=35.0877192982456, Blast_Score=265, Evalue=5e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011299 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 52481; Mature: 52481

Theoretical pI: Translated: 7.98; Mature: 7.98

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTFRLRGYAVSPSNSNNLIRSINMFKNAFANLQKVGKALMLPVSVLPVAGILLGVGAAN
CEEEEEECEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FSWLPEVVSHLMEQAGGSVFGQMPLLFAVGVALGFTNNDGVSGLSAIVGYGIMVATLKVM
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
ATVMGVSGIDTGVLGGILAGGVAAWSFNRFYKIQLPEYLGFFAGKRAVPIITGFISIALG
HHHHCCCCCCHHHHHHHHHHHHHHEECCCEEEEECHHHHHHHCCCCCHHHHHHHHHHHHH
VVLSFIWPPIGSAIATFSDWAANQDPVTAFGIYGIVERSLIPFGLHHIWNVPFFYQAGTC
HHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCE
VNGAGETVNGIMTCFLTADDASRAAGNGFGQLAGGYLFKMFGLPAAAFAIAHCAKPENRA
ECCCCHHHHEEEEEEEECCCCCHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHH
KVMGIMASAALTSFLTGITEPIEFAFLFVAPVLYAIHAVLAGLAYVLTNALGVVHGHTFS
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
NGFIDFVVQSPRADNMLLLVGLGIGYAVLYYVVFTFVIRALNLKTPGREDESADKSASSG
CCCEEEEECCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
NELAGDLVAAFGGKANITNLDACITRLRVSVADTALVDQDKLKKLGAAGVVMVSGGVQAI
CHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEEEECCEEEE
FGTKSDNLKTEMDEWIRNNG
ECCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MLTFRLRGYAVSPSNSNNLIRSINMFKNAFANLQKVGKALMLPVSVLPVAGILLGVGAAN
CEEEEEECEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FSWLPEVVSHLMEQAGGSVFGQMPLLFAVGVALGFTNNDGVSGLSAIVGYGIMVATLKVM
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
ATVMGVSGIDTGVLGGILAGGVAAWSFNRFYKIQLPEYLGFFAGKRAVPIITGFISIALG
HHHHCCCCCCHHHHHHHHHHHHHHEECCCEEEEECHHHHHHHCCCCCHHHHHHHHHHHHH
VVLSFIWPPIGSAIATFSDWAANQDPVTAFGIYGIVERSLIPFGLHHIWNVPFFYQAGTC
HHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCE
VNGAGETVNGIMTCFLTADDASRAAGNGFGQLAGGYLFKMFGLPAAAFAIAHCAKPENRA
ECCCCHHHHEEEEEEEECCCCCHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHH
KVMGIMASAALTSFLTGITEPIEFAFLFVAPVLYAIHAVLAGLAYVLTNALGVVHGHTFS
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
NGFIDFVVQSPRADNMLLLVGLGIGYAVLYYVVFTFVIRALNLKTPGREDESADKSASSG
CCCEEEEECCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
NELAGDLVAAFGGKANITNLDACITRLRVSVADTALVDQDKLKKLGAAGVVMVSGGVQAI
CHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEEEECCEEEE
FGTKSDNLKTEMDEWIRNNG
ECCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]