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The map label for this gene is tcpC [H]

Identifier: 147675545

GI number: 147675545

Start: 383690

End: 385159

Strand: Direct

Name: tcpC [H]

Synonym: VC0395_A0356

Alternate gene names: 147675545

Gene position: 383690-385159 (Clockwise)

Preceding gene: 147673062

Following gene: 147674994

Centisome position: 12.69

GC content: 35.92

Gene sequence:

>1470_bases
ATGAAAAAAACAATAATCAGTACACTTGTTATCGGTTTGGTTGCCGGTTGTTCTAATACGAACTTGCTAAAAGACAATCT
GGCTAGCGAGCAAAATGTCATCAACTTAAGTAAGTCTTCAAACGAAGCGAAATCTAGAAATATTGAATTTCTCTCTGGTG
CCTATTTAAGTGAGAGAAAAGTGCCGAAGCATGACATTAAGTTCAGTGGTAAGTATGTTGAGTTTGAAAGTAAATCACCG
ATTGAGTTAATCGATGTTCTTGATGGACTTTCTAAGCAATATAATATTCAGTATGTATTCTCAGATGAGTTAGAAGATGA
AAAGTCGGAAGAGAATAAAAAGTCATCAGGCTCATCATCGGCGAAGAAAATAAAATACTCAGGACCTCTGGCTGGTTTTT
TTGATTATTTAAGTAGTGCATATAACATGCACTTTGAATTTGGTCATAATAACTTAGTTAAGGCATATCATTATAAAAAT
CAAGTTTTTAACCTCCAGCAATACTTTGATGATAATAAATTTAGCTCGTCAATGCAGATTGGGGGTACCAGTGGCACATC
AAGTGGTCTAAAAGGTACTGCAGATACCGCTATAGAATCTAATAGTTGGAAAAAAATCGATGAGTTTTTAAGTGCATCCT
TAGGTGAAACTGGAAAATTTACAATTTTTGAAGATTATTCACTAGTTACAGTAAAAGCCCGACCTGATAAGTTTTTATTG
TTACATACTTTCTTTGACAAGTTGATCAATGAGAGCAAGATGCAAATCGCGGTTGATTATAGAGTGGTTTCTCTTAGTGA
AGAACGCTTAAATCAGTTAGCTGCCAAATTTGGTATTGAAAATGCAGGGAAATACAGTATTACCAGTGATATGGTCGATG
CGATCTCTTTAAGTCAAGTAGGGGGGGGATTAGGCGCTTCATATCGCTCTGCCTCAGCAAGATTAGATGCAGTGGTTAAT
GAGTTATCACAGGAAGTAATGCATGAGGGGCATTTTATCGGTATCCCTAACAGAGTAATGCCACTAAATGTCACTACAAA
CTCGAAGTATATATCCTCAATCGAAACAACAAAAGATACCAATACTGATGAGGAAACGAGAACTGTCAAAGTTTCTGACT
TAGTAACAGGTTTTAGCATGATGGTTATGCCGAAAATCTTAGATGATGGACGAATTCAAATATCGTCTGGCTTTTCAAGA
AAACAGTTAGTGTCTATTGGTACTGCACAAGGTATTACTCTACCAACAGTTGATGAAAATGAATCAATGAATACCGTAAC
GATGAATCCTGGTGAAGTACGCCTAGCAATGCTATTTAAGGATAATTACATTCAGAATAGTAATGGTGTTCAATTATTAG
GTGGTGGTACTGAAAATAAGAAATCGGCTCGTTATATTGCTGTGCTTGTTGGTGCAAGCAGTTACAAAACCAATGATCTT
GCTAGTAATAGAGTAAATATATATGACTAG

Upstream 100 bases:

>100_bases
TAACTGAGTTGGCTAGCGATATTAACCAAATTGGCATAGACATTAACTTTAAAATATTTCAAAAAAATAAAGTTATTGTC
GTCTATTCAGTGAGATAAGT

Downstream 100 bases:

>100_bases
CATATGGTTACATGAGTCAGATTTTAGATATGTTAACTTAGATGTAGAAAGATACCAAAAAAAATATCGTTTGACATTGA
CTAATGGAAATAAGTACGTA

Product: toxin co-regulated pilus biosynthesis outer membrane protein C

Products: NA

Alternate protein names: TCP pilus biosynthesis protein tcpC [H]

Number of amino acids: Translated: 489; Mature: 489

Protein sequence:

>489_residues
MKKTIISTLVIGLVAGCSNTNLLKDNLASEQNVINLSKSSNEAKSRNIEFLSGAYLSERKVPKHDIKFSGKYVEFESKSP
IELIDVLDGLSKQYNIQYVFSDELEDEKSEENKKSSGSSSAKKIKYSGPLAGFFDYLSSAYNMHFEFGHNNLVKAYHYKN
QVFNLQQYFDDNKFSSSMQIGGTSGTSSGLKGTADTAIESNSWKKIDEFLSASLGETGKFTIFEDYSLVTVKARPDKFLL
LHTFFDKLINESKMQIAVDYRVVSLSEERLNQLAAKFGIENAGKYSITSDMVDAISLSQVGGGLGASYRSASARLDAVVN
ELSQEVMHEGHFIGIPNRVMPLNVTTNSKYISSIETTKDTNTDEETRTVKVSDLVTGFSMMVMPKILDDGRIQISSGFSR
KQLVSIGTAQGITLPTVDENESMNTVTMNPGEVRLAMLFKDNYIQNSNGVQLLGGGTENKKSARYIAVLVGASSYKTNDL
ASNRVNIYD

Sequences:

>Translated_489_residues
MKKTIISTLVIGLVAGCSNTNLLKDNLASEQNVINLSKSSNEAKSRNIEFLSGAYLSERKVPKHDIKFSGKYVEFESKSP
IELIDVLDGLSKQYNIQYVFSDELEDEKSEENKKSSGSSSAKKIKYSGPLAGFFDYLSSAYNMHFEFGHNNLVKAYHYKN
QVFNLQQYFDDNKFSSSMQIGGTSGTSSGLKGTADTAIESNSWKKIDEFLSASLGETGKFTIFEDYSLVTVKARPDKFLL
LHTFFDKLINESKMQIAVDYRVVSLSEERLNQLAAKFGIENAGKYSITSDMVDAISLSQVGGGLGASYRSASARLDAVVN
ELSQEVMHEGHFIGIPNRVMPLNVTTNSKYISSIETTKDTNTDEETRTVKVSDLVTGFSMMVMPKILDDGRIQISSGFSR
KQLVSIGTAQGITLPTVDENESMNTVTMNPGEVRLAMLFKDNYIQNSNGVQLLGGGTENKKSARYIAVLVGASSYKTNDL
ASNRVNIYD
>Mature_489_residues
MKKTIISTLVIGLVAGCSNTNLLKDNLASEQNVINLSKSSNEAKSRNIEFLSGAYLSERKVPKHDIKFSGKYVEFESKSP
IELIDVLDGLSKQYNIQYVFSDELEDEKSEENKKSSGSSSAKKIKYSGPLAGFFDYLSSAYNMHFEFGHNNLVKAYHYKN
QVFNLQQYFDDNKFSSSMQIGGTSGTSSGLKGTADTAIESNSWKKIDEFLSASLGETGKFTIFEDYSLVTVKARPDKFLL
LHTFFDKLINESKMQIAVDYRVVSLSEERLNQLAAKFGIENAGKYSITSDMVDAISLSQVGGGLGASYRSASARLDAVVN
ELSQEVMHEGHFIGIPNRVMPLNVTTNSKYISSIETTKDTNTDEETRTVKVSDLVTGFSMMVMPKILDDGRIQISSGFSR
KQLVSIGTAQGITLPTVDENESMNTVTMNPGEVRLAMLFKDNYIQNSNGVQLLGGGTENKKSARYIAVLVGASSYKTNDL
ASNRVNIYD

Specific function: Involved in TCP pilus biogenesis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Lipid-anchor [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004846 [H]

Pfam domain/function: PF00263 Secretin [H]

EC number: NA

Molecular weight: Translated: 53914; Mature: 53914

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTIISTLVIGLVAGCSNTNLLKDNLASEQNVINLSKSSNEAKSRNIEFLSGAYLSERK
CCHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCEEEECCCCCCHHHCCCEEEECCHHHCCC
VPKHDIKFSGKYVEFESKSPIELIDVLDGLSKQYNIQYVFSDELEDEKSEENKKSSGSSS
CCCCCCEECCEEEEECCCCCHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHCCCCCCC
AKKIKYSGPLAGFFDYLSSAYNMHFEFGHNNLVKAYHYKNQVFNLQQYFDDNKFSSSMQI
CCEEEECCCHHHHHHHHHHHHEEEEEECCCCCEEEEEHHHHHHHHHHHHCCCCCCCCEEE
GGTSGTSSGLKGTADTAIESNSWKKIDEFLSASLGETGKFTIFEDYSLVTVKARPDKFLL
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCEEEEEEECCCCEEE
LHTFFDKLINESKMQIAVDYRVVSLSEERLNQLAAKFGIENAGKYSITSDMVDAISLSQV
HHHHHHHHHCCCCEEEEEEEEEEEECHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHH
GGGLGASYRSASARLDAVVNELSQEVMHEGHFIGIPNRVMPLNVTTNSKYISSIETTKDT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEEEECCCHHHHHHHCCCCC
NTDEETRTVKVSDLVTGFSMMVMPKILDDGRIQISSGFSRKQLVSIGTAQGITLPTVDEN
CCCCHHEEEEHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHEEECCCCCCCCCCCCCC
ESMNTVTMNPGEVRLAMLFKDNYIQNSNGVQLLGGGTENKKSARYIAVLVGASSYKTNDL
CCCCEEEECCCCEEEEEEEECCEEECCCCEEEEECCCCCCCCCEEEEEEEECCCCCCCCC
ASNRVNIYD
CCCCEEECC
>Mature Secondary Structure
MKKTIISTLVIGLVAGCSNTNLLKDNLASEQNVINLSKSSNEAKSRNIEFLSGAYLSERK
CCHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCEEEECCCCCCHHHCCCEEEECCHHHCCC
VPKHDIKFSGKYVEFESKSPIELIDVLDGLSKQYNIQYVFSDELEDEKSEENKKSSGSSS
CCCCCCEECCEEEEECCCCCHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHCCCCCCC
AKKIKYSGPLAGFFDYLSSAYNMHFEFGHNNLVKAYHYKNQVFNLQQYFDDNKFSSSMQI
CCEEEECCCHHHHHHHHHHHHEEEEEECCCCCEEEEEHHHHHHHHHHHHCCCCCCCCEEE
GGTSGTSSGLKGTADTAIESNSWKKIDEFLSASLGETGKFTIFEDYSLVTVKARPDKFLL
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCEEEEEEECCCCEEE
LHTFFDKLINESKMQIAVDYRVVSLSEERLNQLAAKFGIENAGKYSITSDMVDAISLSQV
HHHHHHHHHCCCCEEEEEEEEEEEECHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHH
GGGLGASYRSASARLDAVVNELSQEVMHEGHFIGIPNRVMPLNVTTNSKYISSIETTKDT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEEEECCCHHHHHHHCCCCC
NTDEETRTVKVSDLVTGFSMMVMPKILDDGRIQISSGFSRKQLVSIGTAQGITLPTVDEN
CCCCHHEEEEHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHEEECCCCCCCCCCCCCC
ESMNTVTMNPGEVRLAMLFKDNYIQNSNGVQLLGGGTENKKSARYIAVLVGASSYKTNDL
CCCCEEEECCCCEEEEEEEECCEEECCCCEEEEECCCCCCCCCEEEEEEEECCCCCCCCC
ASNRVNIYD
CCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1358749; 10952301; 8621096 [H]