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The map label for this gene is ydiD [C]

Identifier: 147675212

GI number: 147675212

Start: 2217338

End: 2219143

Strand: Reverse

Name: ydiD [C]

Synonym: VC0395_A2060

Alternate gene names: 147675212

Gene position: 2219143-2217338 (Counterclockwise)

Preceding gene: 147675366

Following gene: 147674433

Centisome position: 73.38

GC content: 46.35

Gene sequence:

>1806_bases
ATGACGAACTTAGATTTCCACATCGTTAAACGGATCCGCCAACGTATTGCCCAAGGGGGTGATAACGCCGCGCTAAAACA
TAAACAAAACGGCCAATGGCAAGCAATCAATTGGCACCAGTTTGGTGAACAATTGGATGAACTCTCGATGGCGTTGTTAG
CTCAAGGCATCGGTGTACAGGACAAAATTGCGATTTTTTCCAACAACATGCCACGTTGGACGATTGCTGATTTTGCCGCC
TTACAGATCCGTGCGGTAACGGTTCCTATCTATCCTACCAATACGCCAGAGCAGGCGGCTTACATCTTACAGAATGCGGA
TGTGAAAGTGGTTTTTGTGGGTGAGCAGGCACAATTTGATGCTGCACTCAGCCAATTTGAACAATGCCCAGAGCTGCGTC
TGATTGTGGCTATGAATGCCAATATCGACCTCAAACAAGCCAGTTGTGCGATGCATTGGGATGAGTTTGTTGCTCAAAGT
CACCATCAAGATCGAGCGCCGTTGGATGCCTTAATTGAGCAGGCCAACTATGACGATCTGTTTACCCTCATTTATACCTC
CGGCACTACCGGAACGCCGAAAGGGGTGATGCTGGATTATCGTAATATCGGTGCTCAGCTAGAGGGACACGATCAGCGCC
TGAATCTGACTCAAGAGGATGTCTCACTCTGTTTCCTGCCACTTTCTCATGTCTTTGAGCGAGCATGGACGGCGTATGTG
CTTTATAAAGGTGCGACCAACTGTTACTTGCAGGACGTGGCTCATGTGCGTGAAGCTTTAGCTGAAGTCCGTCCAACCGT
GATGTGTGCCGTACCGCGCTTTTATGAAAAGATCTTCTCAGCAATCCATGAAAAAGTCGTTAAAGCGCCGTTGGTACGCA
AGGTTCTTTTTACTTGGGCTGTCAATATGGGGGCGAAAATGGCGGTGTGCCGTCAGCAGCAGCGCCAACCTTCTTGGATG
CTTAAACAGAGCCATCAATTCGCTGACAAGCTGGTGTTAAGTAAGCTGCGCGCTTTGCTTGGGGGAAGAATCAATTTCAT
GCCTTGTGGTGGCGCTAAGTTGGATGAAACCATTGGCCGCTTTTTCCATGCGATTGGTATTAACGTCAAGCTTGGTTATG
GCATGACCGAAACCACGGCCACGGTTTCTTGTTGGGATGACCACTGTTTTAACCCAGATTCGATTGGGCTTTCTATGCCG
GGAGCTCAAGTCAAAATTGGCGAGAACAATGAAATTCTGGTTCGTGGTCCTATGGTGATGCGTGGCTACTACAAGCTCGA
TAAAGAAACCACCGAAAGTTTTGATGAGCAGGGTTTTCTGAAAACGGGTGATGCGGGTCATATTGATGAAAATGGTAATT
TATTTATTACCGATCGCATCAAGGAACTGATGAAAACCTCAGGTGGTAAATATATTGCGCCGCAGGTGATTGAAGGGGCG
ATTGGTAAAGATCATTTCATAGAACAGATCGCGGTGATTGCCGATACGCGCAAGTTTGTCTCGGCTTTGATTGTGCCTTG
CTTTGATTCATTGGAAGAGTATGCCAAAGAACTGAACATTAAATATCATGACCGTCTGGAGCTTATCAAACATAGCCAAG
TACTGGAGATGTTTGAAAAGCGCGTTAATGAGTTACAAAAAGAGCTGGCGAAATTTGAACAAGTGAAGAAGTTTAGATTG
TTGCCAAAAGCATTTTCGATGGACAGTGGTGAGCTGACACCGACCCAAAAACTGCGTCGTAAAGTGATTAACGATCGCTA
TCAGGATGAAATCGAAGAAATGTACCAAGATTCTCCGAAAAAATAG

Upstream 100 bases:

>100_bases
TAATCGATAACTTTGACGTTAGTCAGTTGTGTTTTGGCCTTTGAAATGTACACTTGTGCGCTGAAAAAAGGCTTACAGGT
GTAAGCTACAGGTAAGAGAT

Downstream 100 bases:

>100_bases
CGCGATCAAGCTATTATCTTGATGTTCTAAACACCTCTTGGCGAAAATCGCTCAGAGGTGTTTTTATATCTGCAATACTA
TGACCCATGCCCTTGCTACC

Product: putative long-chain-fatty-acid--CoA ligase

Products: NA

Alternate protein names: Long-chain acyl-CoA synthetase; LACS [H]

Number of amino acids: Translated: 601; Mature: 600

Protein sequence:

>601_residues
MTNLDFHIVKRIRQRIAQGGDNAALKHKQNGQWQAINWHQFGEQLDELSMALLAQGIGVQDKIAIFSNNMPRWTIADFAA
LQIRAVTVPIYPTNTPEQAAYILQNADVKVVFVGEQAQFDAALSQFEQCPELRLIVAMNANIDLKQASCAMHWDEFVAQS
HHQDRAPLDALIEQANYDDLFTLIYTSGTTGTPKGVMLDYRNIGAQLEGHDQRLNLTQEDVSLCFLPLSHVFERAWTAYV
LYKGATNCYLQDVAHVREALAEVRPTVMCAVPRFYEKIFSAIHEKVVKAPLVRKVLFTWAVNMGAKMAVCRQQQRQPSWM
LKQSHQFADKLVLSKLRALLGGRINFMPCGGAKLDETIGRFFHAIGINVKLGYGMTETTATVSCWDDHCFNPDSIGLSMP
GAQVKIGENNEILVRGPMVMRGYYKLDKETTESFDEQGFLKTGDAGHIDENGNLFITDRIKELMKTSGGKYIAPQVIEGA
IGKDHFIEQIAVIADTRKFVSALIVPCFDSLEEYAKELNIKYHDRLELIKHSQVLEMFEKRVNELQKELAKFEQVKKFRL
LPKAFSMDSGELTPTQKLRRKVINDRYQDEIEEMYQDSPKK

Sequences:

>Translated_601_residues
MTNLDFHIVKRIRQRIAQGGDNAALKHKQNGQWQAINWHQFGEQLDELSMALLAQGIGVQDKIAIFSNNMPRWTIADFAA
LQIRAVTVPIYPTNTPEQAAYILQNADVKVVFVGEQAQFDAALSQFEQCPELRLIVAMNANIDLKQASCAMHWDEFVAQS
HHQDRAPLDALIEQANYDDLFTLIYTSGTTGTPKGVMLDYRNIGAQLEGHDQRLNLTQEDVSLCFLPLSHVFERAWTAYV
LYKGATNCYLQDVAHVREALAEVRPTVMCAVPRFYEKIFSAIHEKVVKAPLVRKVLFTWAVNMGAKMAVCRQQQRQPSWM
LKQSHQFADKLVLSKLRALLGGRINFMPCGGAKLDETIGRFFHAIGINVKLGYGMTETTATVSCWDDHCFNPDSIGLSMP
GAQVKIGENNEILVRGPMVMRGYYKLDKETTESFDEQGFLKTGDAGHIDENGNLFITDRIKELMKTSGGKYIAPQVIEGA
IGKDHFIEQIAVIADTRKFVSALIVPCFDSLEEYAKELNIKYHDRLELIKHSQVLEMFEKRVNELQKELAKFEQVKKFRL
LPKAFSMDSGELTPTQKLRRKVINDRYQDEIEEMYQDSPKK
>Mature_600_residues
TNLDFHIVKRIRQRIAQGGDNAALKHKQNGQWQAINWHQFGEQLDELSMALLAQGIGVQDKIAIFSNNMPRWTIADFAAL
QIRAVTVPIYPTNTPEQAAYILQNADVKVVFVGEQAQFDAALSQFEQCPELRLIVAMNANIDLKQASCAMHWDEFVAQSH
HQDRAPLDALIEQANYDDLFTLIYTSGTTGTPKGVMLDYRNIGAQLEGHDQRLNLTQEDVSLCFLPLSHVFERAWTAYVL
YKGATNCYLQDVAHVREALAEVRPTVMCAVPRFYEKIFSAIHEKVVKAPLVRKVLFTWAVNMGAKMAVCRQQQRQPSWML
KQSHQFADKLVLSKLRALLGGRINFMPCGGAKLDETIGRFFHAIGINVKLGYGMTETTATVSCWDDHCFNPDSIGLSMPG
AQVKIGENNEILVRGPMVMRGYYKLDKETTESFDEQGFLKTGDAGHIDENGNLFITDRIKELMKTSGGKYIAPQVIEGAI
GKDHFIEQIAVIADTRKFVSALIVPCFDSLEEYAKELNIKYHDRLELIKHSQVLEMFEKRVNELQKELAKFEQVKKFRLL
PKAFSMDSGELTPTQKLRRKVINDRYQDEIEEMYQDSPKK

Specific function: Unknown

COG id: COG1022

COG function: function code I; Long-chain acyl-CoA synthetases (AMP-forming)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

Organism=Homo sapiens, GI27477105, Length=635, Percent_Identity=29.7637795275591, Blast_Score=250, Evalue=3e-66,
Organism=Homo sapiens, GI42794756, Length=602, Percent_Identity=29.0697674418605, Blast_Score=238, Evalue=2e-62,
Organism=Homo sapiens, GI42794760, Length=602, Percent_Identity=29.0697674418605, Blast_Score=238, Evalue=2e-62,
Organism=Homo sapiens, GI42794758, Length=602, Percent_Identity=29.0697674418605, Blast_Score=238, Evalue=2e-62,
Organism=Homo sapiens, GI40807491, Length=616, Percent_Identity=28.8961038961039, Blast_Score=232, Evalue=6e-61,
Organism=Homo sapiens, GI57165412, Length=624, Percent_Identity=29.8076923076923, Blast_Score=231, Evalue=2e-60,
Organism=Homo sapiens, GI57165410, Length=624, Percent_Identity=29.6474358974359, Blast_Score=228, Evalue=1e-59,
Organism=Homo sapiens, GI83745141, Length=614, Percent_Identity=27.3615635179153, Blast_Score=227, Evalue=2e-59,
Organism=Homo sapiens, GI42794754, Length=611, Percent_Identity=28.1505728314239, Blast_Score=193, Evalue=4e-49,
Organism=Homo sapiens, GI42794752, Length=611, Percent_Identity=28.1505728314239, Blast_Score=193, Evalue=4e-49,
Organism=Homo sapiens, GI12669909, Length=606, Percent_Identity=23.4323432343234, Blast_Score=159, Evalue=5e-39,
Organism=Homo sapiens, GI4758332, Length=606, Percent_Identity=23.4323432343234, Blast_Score=159, Evalue=5e-39,
Organism=Homo sapiens, GI187761345, Length=473, Percent_Identity=23.2558139534884, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI187761343, Length=473, Percent_Identity=23.2558139534884, Blast_Score=87, Evalue=4e-17,
Organism=Escherichia coli, GI145693145, Length=581, Percent_Identity=25.473321858864, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI221142682, Length=482, Percent_Identity=21.5767634854772, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI1788107, Length=475, Percent_Identity=21.6842105263158, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1789201, Length=357, Percent_Identity=22.96918767507, Blast_Score=66, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17556552, Length=617, Percent_Identity=28.0388978930308, Blast_Score=246, Evalue=2e-65,
Organism=Caenorhabditis elegans, GI17510401, Length=619, Percent_Identity=30.048465266559, Blast_Score=224, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI17541856, Length=593, Percent_Identity=29.6795952782462, Blast_Score=218, Evalue=9e-57,
Organism=Caenorhabditis elegans, GI17553312, Length=601, Percent_Identity=26.7886855241265, Blast_Score=189, Evalue=4e-48,
Organism=Caenorhabditis elegans, GI193204819, Length=629, Percent_Identity=28.4578696343402, Blast_Score=187, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17564090, Length=547, Percent_Identity=27.4223034734918, Blast_Score=184, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI25147511, Length=607, Percent_Identity=24.8764415156507, Blast_Score=182, Evalue=6e-46,
Organism=Caenorhabditis elegans, GI17531443, Length=500, Percent_Identity=24.2, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17558820, Length=497, Percent_Identity=25.5533199195171, Blast_Score=106, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17559526, Length=417, Percent_Identity=25.4196642685851, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI133901848, Length=220, Percent_Identity=29.0909090909091, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI32563687, Length=285, Percent_Identity=25.9649122807018, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71985884, Length=357, Percent_Identity=25.7703081232493, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17557194, Length=137, Percent_Identity=33.5766423357664, Blast_Score=69, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6324893, Length=457, Percent_Identity=29.1028446389497, Blast_Score=166, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6320852, Length=584, Percent_Identity=25.1712328767123, Blast_Score=162, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6322182, Length=445, Percent_Identity=27.6404494382022, Blast_Score=154, Evalue=4e-38,
Organism=Saccharomyces cerevisiae, GI6323903, Length=446, Percent_Identity=26.2331838565022, Blast_Score=138, Evalue=2e-33,
Organism=Drosophila melanogaster, GI281366413, Length=600, Percent_Identity=31.1666666666667, Blast_Score=239, Evalue=6e-63,
Organism=Drosophila melanogaster, GI24666501, Length=600, Percent_Identity=31.1666666666667, Blast_Score=238, Evalue=7e-63,
Organism=Drosophila melanogaster, GI24666497, Length=600, Percent_Identity=31.1666666666667, Blast_Score=238, Evalue=7e-63,
Organism=Drosophila melanogaster, GI19921316, Length=626, Percent_Identity=27.6357827476038, Blast_Score=214, Evalue=1e-55,
Organism=Drosophila melanogaster, GI17933690, Length=626, Percent_Identity=25.0798722044728, Blast_Score=214, Evalue=1e-55,
Organism=Drosophila melanogaster, GI62471679, Length=596, Percent_Identity=27.8523489932886, Blast_Score=186, Evalue=4e-47,
Organism=Drosophila melanogaster, GI62471683, Length=596, Percent_Identity=27.8523489932886, Blast_Score=186, Evalue=4e-47,
Organism=Drosophila melanogaster, GI62471685, Length=596, Percent_Identity=27.8523489932886, Blast_Score=186, Evalue=4e-47,
Organism=Drosophila melanogaster, GI24586636, Length=596, Percent_Identity=27.8523489932886, Blast_Score=186, Evalue=4e-47,
Organism=Drosophila melanogaster, GI62471689, Length=596, Percent_Identity=28.5234899328859, Blast_Score=186, Evalue=5e-47,
Organism=Drosophila melanogaster, GI62471681, Length=596, Percent_Identity=27.8523489932886, Blast_Score=186, Evalue=5e-47,
Organism=Drosophila melanogaster, GI62471687, Length=596, Percent_Identity=27.8523489932886, Blast_Score=186, Evalue=5e-47,
Organism=Drosophila melanogaster, GI24586634, Length=596, Percent_Identity=27.8523489932886, Blast_Score=186, Evalue=5e-47,
Organism=Drosophila melanogaster, GI22026970, Length=596, Percent_Identity=27.8523489932886, Blast_Score=186, Evalue=5e-47,
Organism=Drosophila melanogaster, GI21355181, Length=500, Percent_Identity=26.6, Blast_Score=119, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.3 [H]

Molecular weight: Translated: 68188; Mature: 68057

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNLDFHIVKRIRQRIAQGGDNAALKHKQNGQWQAINWHQFGEQLDELSMALLAQGIGVQ
CCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEECHHHHHHHHHHHHHHHHHHCCCCC
DKIAIFSNNMPRWTIADFAALQIRAVTVPIYPTNTPEQAAYILQNADVKVVFVGEQAQFD
CEEEEEECCCCCEEHHHHHEEEEEEEEEEEECCCCHHHHHHHHCCCCEEEEEECCCHHHH
AALSQFEQCPELRLIVAMNANIDLKQASCAMHWDEFVAQSHHQDRAPLDALIEQANYDDL
HHHHHHHCCCCEEEEEEECCCCEEHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCE
FTLIYTSGTTGTPKGVMLDYRNIGAQLEGHDQRLNLTQEDVSLCFLPLSHVFERAWTAYV
EEEEEECCCCCCCCCEEEEHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEE
LYKGATNCYLQDVAHVREALAEVRPTVMCAVPRFYEKIFSAIHEKVVKAPLVRKVLFTWA
EECCCCHHHHHHHHHHHHHHHHHCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNMGAKMAVCRQQQRQPSWMLKQSHQFADKLVLSKLRALLGGRINFMPCGGAKLDETIGR
HCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHH
FFHAIGINVKLGYGMTETTATVSCWDDHCFNPDSIGLSMPGAQVKIGENNEILVRGPMVM
HHHHHCCEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEECCCCEEEEECCHHH
RGYYKLDKETTESFDEQGFLKTGDAGHIDENGNLFITDRIKELMKTSGGKYIAPQVIEGA
HHHHHCCCHHHHHHHHCCCEECCCCCCCCCCCCEEEHHHHHHHHHCCCCCEECHHHHHCC
IGKDHFIEQIAVIADTRKFVSALIVPCFDSLEEYAKELNIKYHDRLELIKHSQVLEMFEK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
RVNELQKELAKFEQVKKFRLLPKAFSMDSGELTPTQKLRRKVINDRYQDEIEEMYQDSPK
HHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCC
K
C
>Mature Secondary Structure 
TNLDFHIVKRIRQRIAQGGDNAALKHKQNGQWQAINWHQFGEQLDELSMALLAQGIGVQ
CCCHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEECHHHHHHHHHHHHHHHHHHCCCCC
DKIAIFSNNMPRWTIADFAALQIRAVTVPIYPTNTPEQAAYILQNADVKVVFVGEQAQFD
CEEEEEECCCCCEEHHHHHEEEEEEEEEEEECCCCHHHHHHHHCCCCEEEEEECCCHHHH
AALSQFEQCPELRLIVAMNANIDLKQASCAMHWDEFVAQSHHQDRAPLDALIEQANYDDL
HHHHHHHCCCCEEEEEEECCCCEEHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCE
FTLIYTSGTTGTPKGVMLDYRNIGAQLEGHDQRLNLTQEDVSLCFLPLSHVFERAWTAYV
EEEEEECCCCCCCCCEEEEHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEE
LYKGATNCYLQDVAHVREALAEVRPTVMCAVPRFYEKIFSAIHEKVVKAPLVRKVLFTWA
EECCCCHHHHHHHHHHHHHHHHHCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNMGAKMAVCRQQQRQPSWMLKQSHQFADKLVLSKLRALLGGRINFMPCGGAKLDETIGR
HCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHH
FFHAIGINVKLGYGMTETTATVSCWDDHCFNPDSIGLSMPGAQVKIGENNEILVRGPMVM
HHHHHCCEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEECCCCEEEEECCHHH
RGYYKLDKETTESFDEQGFLKTGDAGHIDENGNLFITDRIKELMKTSGGKYIAPQVIEGA
HHHHHCCCHHHHHHHHCCCEECCCCCCCCCCCCEEEHHHHHHHHHCCCCCEECHHHHHCC
IGKDHFIEQIAVIADTRKFVSALIVPCFDSLEEYAKELNIKYHDRLELIKHSQVLEMFEK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
RVNELQKELAKFEQVKKFRLLPKAFSMDSGELTPTQKLRRKVINDRYQDEIEEMYQDSPK
HHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]