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The map label for this gene is msrB [H]

Identifier: 147675201

GI number: 147675201

Start: 868948

End: 869394

Strand: Direct

Name: msrB [H]

Synonym: VC0395_A0857

Alternate gene names: 147675201

Gene position: 868948-869394 (Clockwise)

Preceding gene: 147675652

Following gene: 147674708

Centisome position: 28.73

GC content: 49.44

Gene sequence:

>447_bases
ATGTTGAACTGGCAACAGGTGTTGGATTTTGCAAACCAAGGCAATCCTAAGCCAGAGCGTGAAGTGACGCGCAGTGATGA
AGAGTGGCGCACTTTGCTTGATGAACAGCAGTATTACGTGATGCGTCAACATGGCACAGAGAGAGCCTTTTCTAATGCGA
TGTGTGAGCTGTTTGAGCCGGGTTTATACCAATGTGCCGGTTGCCAAACCCTGTTATTTGATTCGGCAACCAAATTTGAT
TCAGGCACAGGCTGGCCTTCGTTTTCGCAGCCAGTCAAATTCAATGCCATTTCCTACCATATGGATCAAAGCTTAGCGCG
TGCTCGAGTGGAAGTGCGTTGTAACACTTGCGAGTCGCACCTAGGGCATGTGTTTCCTGATGGGCCGCCGCCAAGCGGTT
TGCGTTACTGCATCAATTCGGTTGCCGTGAACAAACTCAGTGCATAA

Upstream 100 bases:

>100_bases
GCAATAAGATTGGTGCATCCGCGGTCTATATTCTTCCAGCTTGACGCTGCCGTACTAAGTCGTTTGAGCATAGTCAATAG
TCCAACAAGAGGAGAGAGCA

Downstream 100 bases:

>100_bases
ATATACCCTTCCTACTTGAAGTTGCAGCGGTGTTGGCTACGTTCGTTCACCCCAATCACATAGTTTGCCTATGCTCATGG
GGATTCACTTACTTGCCGCC

Product: PilB-related protein

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MLNWQQVLDFANQGNPKPEREVTRSDEEWRTLLDEQQYYVMRQHGTERAFSNAMCELFEPGLYQCAGCQTLLFDSATKFD
SGTGWPSFSQPVKFNAISYHMDQSLARARVEVRCNTCESHLGHVFPDGPPPSGLRYCINSVAVNKLSA

Sequences:

>Translated_148_residues
MLNWQQVLDFANQGNPKPEREVTRSDEEWRTLLDEQQYYVMRQHGTERAFSNAMCELFEPGLYQCAGCQTLLFDSATKFD
SGTGWPSFSQPVKFNAISYHMDQSLARARVEVRCNTCESHLGHVFPDGPPPSGLRYCINSVAVNKLSA
>Mature_148_residues
MLNWQQVLDFANQGNPKPEREVTRSDEEWRTLLDEQQYYVMRQHGTERAFSNAMCELFEPGLYQCAGCQTLLFDSATKFD
SGTGWPSFSQPVKFNAISYHMDQSLARARVEVRCNTCESHLGHVFPDGPPPSGLRYCINSVAVNKLSA

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI37620216, Length=124, Percent_Identity=47.5806451612903, Blast_Score=124, Evalue=4e-29,
Organism=Homo sapiens, GI301336164, Length=124, Percent_Identity=47.5806451612903, Blast_Score=124, Evalue=4e-29,
Organism=Homo sapiens, GI301336162, Length=124, Percent_Identity=47.5806451612903, Blast_Score=124, Evalue=4e-29,
Organism=Homo sapiens, GI73089054, Length=124, Percent_Identity=47.5806451612903, Blast_Score=124, Evalue=4e-29,
Organism=Homo sapiens, GI117606353, Length=131, Percent_Identity=46.5648854961832, Blast_Score=121, Evalue=2e-28,
Organism=Escherichia coli, GI1788077, Length=119, Percent_Identity=48.7394957983193, Blast_Score=127, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17553450, Length=133, Percent_Identity=43.609022556391, Blast_Score=107, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI115532676, Length=133, Percent_Identity=43.609022556391, Blast_Score=107, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6319816, Length=127, Percent_Identity=40.9448818897638, Blast_Score=98, Evalue=5e-22,
Organism=Drosophila melanogaster, GI45553335, Length=129, Percent_Identity=44.9612403100775, Blast_Score=121, Evalue=2e-28,
Organism=Drosophila melanogaster, GI21356369, Length=129, Percent_Identity=44.9612403100775, Blast_Score=121, Evalue=2e-28,
Organism=Drosophila melanogaster, GI221378664, Length=125, Percent_Identity=44.8, Blast_Score=121, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24645799, Length=129, Percent_Identity=44.9612403100775, Blast_Score=121, Evalue=2e-28,
Organism=Drosophila melanogaster, GI221378662, Length=132, Percent_Identity=42.4242424242424, Blast_Score=119, Evalue=6e-28,
Organism=Drosophila melanogaster, GI24645804, Length=140, Percent_Identity=41.4285714285714, Blast_Score=117, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24645801, Length=140, Percent_Identity=41.4285714285714, Blast_Score=117, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 16799; Mature: 16799

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNWQQVLDFANQGNPKPEREVTRSDEEWRTLLDEQQYYVMRQHGTERAFSNAMCELFEP
CCCHHHHHHHHHCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
GLYQCAGCQTLLFDSATKFDSGTGWPSFSQPVKFNAISYHMDQSLARARVEVRCNTCESH
CCHHHHCCHHHHHCCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHCCHHHHH
LGHVFPDGPPPSGLRYCINSVAVNKLSA
CCCCCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLNWQQVLDFANQGNPKPEREVTRSDEEWRTLLDEQQYYVMRQHGTERAFSNAMCELFEP
CCCHHHHHHHHHCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
GLYQCAGCQTLLFDSATKFDSGTGWPSFSQPVKFNAISYHMDQSLARARVEVRCNTCESH
CCHHHHCCHHHHHCCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHCCHHHHH
LGHVFPDGPPPSGLRYCINSVAVNKLSA
CCCCCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]