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The map label for this gene is aroC [H]

Identifier: 147675123

GI number: 147675123

Start: 1825313

End: 1826398

Strand: Reverse

Name: aroC [H]

Synonym: VC0395_A1699

Alternate gene names: 147675123

Gene position: 1826398-1825313 (Counterclockwise)

Preceding gene: 147673603

Following gene: 147673720

Centisome position: 60.4

GC content: 51.01

Gene sequence:

>1086_bases
ATGGCAGGAAACAGTATCGGACAACATTTCCGAGTCACCACATTCGGAGAAAGTCACGGTATCGCACTGGGATGTATTGT
CGATGGTTGCCCACCGGGGCTCACCATCAGCGAAGCGGATTTACAAGTGGATCTTGACCGTCGTCGCCCCGGCACATCGC
GTTATACCACCCAGCGTCGCGAGCCGGATGAAGTCAAAATTCTCTCTGGTGTGTTTGAGGGCAAAACCACAGGCACATCG
ATTGGGCTATTGATCGAAAACACTGACCAACGCTCTAAAGATTATTCGGATATTAAAGACAAATTCCGTCCCGGACATGC
GGACTACACCTATCATCAAAAGTACGGTGTGCGAGATTACCGTGGCGGCGGCCGTTCATCGGCACGTGAAACCGCCATGC
GTGTTGCGGCGGGAGCGATTGCCAAAAAATACCTGCAGCAAGAGTTTGGCATTGAAGTGCGTGCTTACTTGTCGCAAATG
GGGGAGGTCGCGATTGATAAAGTGGATTGGAATGAGATTGAAAACAACGATTTCTTCTGCCCTGATGTCGATAAAGTGGC
TGCGTTTGACGAGCTGATCCGCGAGCTGAAAAAAGAAGGCGATTCGATCGGCGCCAAAATCCAAGTGGTTGCTACTGGCG
TTCCAGTTGGCTTGGGTGAGCCTGTGTTTGATCGCTTAGATGCGGATATTGCCCATGCCTTGATGAGCATCAACGCCGTG
AAAGGAGTCGAGATTGGTGATGGCTTTGATGTAGTGCGCCAAAAAGGCAGCCAACATCGTGACCCGCTCACTCCACAAGG
TTTCCGCTCTAACCATTCCGGTGGCATTTTAGGCGGTATCTCTAGCGGGCAAGATATTGTTGCTAATATTGCGTTGAAGC
CAACGTCCAGCATTACCGTGCCGGGTGAAACAATTGATGTTAACGGTGAGCCAACCGAGCTTATCACCAAAGGTCGTCAT
GACCCTTGTGTGGGGATTCGCGCTGTACCGATTGCAGAAGCCATGTTGGCGATTGTGCTGATGGATCATCTGCTGCGTCA
TCGTGGTCAGAACCAAGGTGTCGTAACGACAACACCGAAAATTTAG

Upstream 100 bases:

>100_bases
CATTTTTAGGACTTTACATCACAAAGCATTAACGCCACTATGAAGCCACGAAGAACAGTTAATCAGTGAAACTGGAGTTT
CACTGTGCATTGAGGAAGTC

Downstream 100 bases:

>100_bases
TGATGCGCTAACCCCTGTAAAGAGCCCAACGCCCTCGATTGAGGGCGTTGTCATATCCGCTTAATTTACCGCCGGGGCAG
GCTAGTGAATGGAGTTCTCG

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase [H]

Number of amino acids: Translated: 361; Mature: 360

Protein sequence:

>361_residues
MAGNSIGQHFRVTTFGESHGIALGCIVDGCPPGLTISEADLQVDLDRRRPGTSRYTTQRREPDEVKILSGVFEGKTTGTS
IGLLIENTDQRSKDYSDIKDKFRPGHADYTYHQKYGVRDYRGGGRSSARETAMRVAAGAIAKKYLQQEFGIEVRAYLSQM
GEVAIDKVDWNEIENNDFFCPDVDKVAAFDELIRELKKEGDSIGAKIQVVATGVPVGLGEPVFDRLDADIAHALMSINAV
KGVEIGDGFDVVRQKGSQHRDPLTPQGFRSNHSGGILGGISSGQDIVANIALKPTSSITVPGETIDVNGEPTELITKGRH
DPCVGIRAVPIAEAMLAIVLMDHLLRHRGQNQGVVTTTPKI

Sequences:

>Translated_361_residues
MAGNSIGQHFRVTTFGESHGIALGCIVDGCPPGLTISEADLQVDLDRRRPGTSRYTTQRREPDEVKILSGVFEGKTTGTS
IGLLIENTDQRSKDYSDIKDKFRPGHADYTYHQKYGVRDYRGGGRSSARETAMRVAAGAIAKKYLQQEFGIEVRAYLSQM
GEVAIDKVDWNEIENNDFFCPDVDKVAAFDELIRELKKEGDSIGAKIQVVATGVPVGLGEPVFDRLDADIAHALMSINAV
KGVEIGDGFDVVRQKGSQHRDPLTPQGFRSNHSGGILGGISSGQDIVANIALKPTSSITVPGETIDVNGEPTELITKGRH
DPCVGIRAVPIAEAMLAIVLMDHLLRHRGQNQGVVTTTPKI
>Mature_360_residues
AGNSIGQHFRVTTFGESHGIALGCIVDGCPPGLTISEADLQVDLDRRRPGTSRYTTQRREPDEVKILSGVFEGKTTGTSI
GLLIENTDQRSKDYSDIKDKFRPGHADYTYHQKYGVRDYRGGGRSSARETAMRVAAGAIAKKYLQQEFGIEVRAYLSQMG
EVAIDKVDWNEIENNDFFCPDVDKVAAFDELIRELKKEGDSIGAKIQVVATGVPVGLGEPVFDRLDADIAHALMSINAVK
GVEIGDGFDVVRQKGSQHRDPLTPQGFRSNHSGGILGGISSGQDIVANIALKPTSSITVPGETIDVNGEPTELITKGRHD
PCVGIRAVPIAEAMLAIVLMDHLLRHRGQNQGVVTTTPKI

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788669, Length=360, Percent_Identity=79.7222222222222, Blast_Score=570, Evalue=1e-164,
Organism=Saccharomyces cerevisiae, GI6321290, Length=369, Percent_Identity=45.5284552845528, Blast_Score=311, Evalue=1e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000453
- InterPro:   IPR020541 [H]

Pfam domain/function: PF01264 Chorismate_synt [H]

EC number: =4.2.3.5 [H]

Molecular weight: Translated: 39106; Mature: 38974

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1 ; PS00788 CHORISMATE_SYNTHASE_2 ; PS00789 CHORISMATE_SYNTHASE_3 ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGNSIGQHFRVTTFGESHGIALGCIVDGCPPGLTISEADLQVDLDRRRPGTSRYTTQRR
CCCCCCCCCEEEEEECCCCCEEEEEEECCCCCCCEEECCCEEEECCCCCCCCCCCCCCCC
EPDEVKILSGVFEGKTTGTSIGLLIENTDQRSKDYSDIKDKFRPGHADYTYHQKYGVRDY
CCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHCCCCCCCCEEHHHCCCCCC
RGGGRSSARETAMRVAAGAIAKKYLQQEFGIEVRAYLSQMGEVAIDKVDWNEIENNDFFC
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEEECCCCCCCCCCCCCC
PDVDKVAAFDELIRELKKEGDSIGAKIQVVATGVPVGLGEPVFDRLDADIAHALMSINAV
CCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
KGVEIGDGFDVVRQKGSQHRDPLTPQGFRSNHSGGILGGISSGQDIVANIALKPTSSITV
CCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEEEEEEECCCCCEEC
PGETIDVNGEPTELITKGRHDPCVGIRAVPIAEAMLAIVLMDHLLRHRGQNQGVVTTTPK
CCCEEECCCCCHHHHHCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHCCCCCCEEEECCC
I
C
>Mature Secondary Structure 
AGNSIGQHFRVTTFGESHGIALGCIVDGCPPGLTISEADLQVDLDRRRPGTSRYTTQRR
CCCCCCCCEEEEEECCCCCEEEEEEECCCCCCCEEECCCEEEECCCCCCCCCCCCCCCC
EPDEVKILSGVFEGKTTGTSIGLLIENTDQRSKDYSDIKDKFRPGHADYTYHQKYGVRDY
CCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHCCCCCCCCEEHHHCCCCCC
RGGGRSSARETAMRVAAGAIAKKYLQQEFGIEVRAYLSQMGEVAIDKVDWNEIENNDFFC
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEEECCCCCCCCCCCCCC
PDVDKVAAFDELIRELKKEGDSIGAKIQVVATGVPVGLGEPVFDRLDADIAHALMSINAV
CCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
KGVEIGDGFDVVRQKGSQHRDPLTPQGFRSNHSGGILGGISSGQDIVANIALKPTSSITV
CCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEEEEEEECCCCCEEC
PGETIDVNGEPTELITKGRHDPCVGIRAVPIAEAMLAIVLMDHLLRHRGQNQGVVTTTPK
CCCEEECCCCCHHHHHCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHCCCCCCEEEECCC
I
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8021209 [H]