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The map label for this gene is mdtA [H]

Identifier: 147675113

GI number: 147675113

Start: 1361334

End: 1362413

Strand: Reverse

Name: mdtA [H]

Synonym: VC0395_A1279

Alternate gene names: 147675113

Gene position: 1362413-1361334 (Counterclockwise)

Preceding gene: 147673434

Following gene: 147674680

Centisome position: 45.05

GC content: 49.26

Gene sequence:

>1080_bases
ATGAAAATAATTCGTTACACCGCTTGGTTGGCTCACTTACTGTTGATCGCAGGATGCAGTGAACCCACGAAGCTTGAACG
CGATACGCTACCGCGAGTAAAGGTGGCGCAGGCAGGTGAAAAAGTCAGTGATAAGCTCTTTTTTCCTGCGGTGGCCAATG
CGGCTGAACGTTCTCATTTGAGTTTTCGAGTGGCAGGTGAAATCAGTAAGTTCCATGTCAAAGAGGGCGCTCGCGTTAAG
CAAGGCGACATCTTGGCTGAAATTGAGCCGACCGATTACCGTTTGGCTGTCGATAATGCTCAAGCACGATTTTCCGTGAT
TGATAGCCAATATCGGCGTTCACAACCACTGGTCGAAAAAGGCTTATTAGCCAAATCACAGTTTGACGAAATTGCTGCGC
AGCGCCAAATCGCTCGTGCTGAGCTTGAGTTGGCGAAACTTCGTCTCTCCTTCACCCAATTACGCGCACCAATGGATGGC
ATCATCTCGCGTGTCAGCGCTGAGCAGTTTGAAAGTGTTCAGGTTGGCCAACAAATCGTCAATATTCACAATATCGATAG
CGTTGAAGTTTTGATTCAACTGCCTGATCGCCTGTATGCGACACAACCGACGGCCAGCGAGTTGGCGAAGATAGAAACCG
TGGTGCGTGTCCCAAGTGGTCAAGTTTATCCCGCACGTATCAAAGAATTCACCACTGAGCCAGACCCTGCCACGGGGACA
TTTACTGTCACCCTTTCTCTGCCCATGCCAGAGCAAGAACTGATCTTGGATGGCATGGCTGTTGAAGTGAGTGCCAAAGG
GCAACATGTCGGGCTAAACCCACTCAACACCATCAGTATTCCGATTGAGGCGATTTTTAATGCCGACGGTGATGAGTTAG
ACAAAACTGCTCAATATGTTTGGTTGCTCAACAACGACAATACGGTGAGCAAACGTCAGGTGCGGTTAGCGAAAGCGTCA
CGCAGCCATGTTCAAGTCAGTGAAGGAATTAACGCGGGAGATCGTTTAGTGGTCGCTGGCGTTGCAAGATTGAGAGATGG
AATGAAAGTACAAATCCTTGAGGAGCGTGGCCATGAGTGA

Upstream 100 bases:

>100_bases
ACAGGTTTAAATGATGGTGACCGGATCATTATTTCCGGTGTCAGTGGTGTGACCGAGGGCATAAAAGTGCGTGAATGGGT
CAAGGAGCGAGGACTGTAGG

Downstream 100 bases:

>100_bases
ACAGAAGCAGACCCCGCCAGAGAATTATGAGAACCAAGGTGTTGCCGCTTACTTCATCAATAATCGCGTGATCAGTTGGA
TGGTTTCGCTGATTTTTTTG

Product: HlyD family secretion protein

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MKIIRYTAWLAHLLLIAGCSEPTKLERDTLPRVKVAQAGEKVSDKLFFPAVANAAERSHLSFRVAGEISKFHVKEGARVK
QGDILAEIEPTDYRLAVDNAQARFSVIDSQYRRSQPLVEKGLLAKSQFDEIAAQRQIARAELELAKLRLSFTQLRAPMDG
IISRVSAEQFESVQVGQQIVNIHNIDSVEVLIQLPDRLYATQPTASELAKIETVVRVPSGQVYPARIKEFTTEPDPATGT
FTVTLSLPMPEQELILDGMAVEVSAKGQHVGLNPLNTISIPIEAIFNADGDELDKTAQYVWLLNNDNTVSKRQVRLAKAS
RSHVQVSEGINAGDRLVVAGVARLRDGMKVQILEERGHE

Sequences:

>Translated_359_residues
MKIIRYTAWLAHLLLIAGCSEPTKLERDTLPRVKVAQAGEKVSDKLFFPAVANAAERSHLSFRVAGEISKFHVKEGARVK
QGDILAEIEPTDYRLAVDNAQARFSVIDSQYRRSQPLVEKGLLAKSQFDEIAAQRQIARAELELAKLRLSFTQLRAPMDG
IISRVSAEQFESVQVGQQIVNIHNIDSVEVLIQLPDRLYATQPTASELAKIETVVRVPSGQVYPARIKEFTTEPDPATGT
FTVTLSLPMPEQELILDGMAVEVSAKGQHVGLNPLNTISIPIEAIFNADGDELDKTAQYVWLLNNDNTVSKRQVRLAKAS
RSHVQVSEGINAGDRLVVAGVARLRDGMKVQILEERGHE
>Mature_359_residues
MKIIRYTAWLAHLLLIAGCSEPTKLERDTLPRVKVAQAGEKVSDKLFFPAVANAAERSHLSFRVAGEISKFHVKEGARVK
QGDILAEIEPTDYRLAVDNAQARFSVIDSQYRRSQPLVEKGLLAKSQFDEIAAQRQIARAELELAKLRLSFTQLRAPMDG
IISRVSAEQFESVQVGQQIVNIHNIDSVEVLIQLPDRLYATQPTASELAKIETVVRVPSGQVYPARIKEFTTEPDPATGT
FTVTLSLPMPEQELILDGMAVEVSAKGQHVGLNPLNTISIPIEAIFNADGDELDKTAQYVWLLNNDNTVSKRQVRLAKAS
RSHVQVSEGINAGDRLVVAGVARLRDGMKVQILEERGHE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=331, Percent_Identity=27.4924471299094, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI1786668, Length=333, Percent_Identity=26.1261261261261, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789665, Length=371, Percent_Identity=24.2587601078167, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789929, Length=332, Percent_Identity=26.2048192771084, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081796, Length=325, Percent_Identity=23.3846153846154, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 39689; Mature: 39689

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIRYTAWLAHLLLIAGCSEPTKLERDTLPRVKVAQAGEKVSDKLFFPAVANAAERSHL
CCEEHHHHHHHHHHHHHCCCCCCCCCHHCCCCCHHHHCCCHHHHCEECHHHHHHHHHCCE
SFRVAGEISKFHVKEGARVKQGDILAEIEPTDYRLAVDNAQARFSVIDSQYRRSQPLVEK
EEEEECCCCEEECCCCCEEECCCEEEEECCCCEEEEECCCCHHHHHHHHHHHHCCCHHHH
GLLAKSQFDEIAAQRQIARAELELAKLRLSFTQLRAPMDGIISRVSAEQFESVQVGQQIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
NIHNIDSVEVLIQLPDRLYATQPTASELAKIETVVRVPSGQVYPARIKEFTTEPDPATGT
HHCCCCCEEEEEECCHHHHCCCCCHHHHHHHHHHEECCCCCCCHHHHHHCCCCCCCCCCE
FTVTLSLPMPEQELILDGMAVEVSAKGQHVGLNPLNTISIPIEAIFNADGDELDKTAQYV
EEEEEECCCCHHHHHCCCEEEEEECCCCEECCCCCCEEEEEEEEEECCCCHHHHCCEEEE
WLLNNDNTVSKRQVRLAKASRSHVQVSEGINAGDRLVVAGVARLRDGMKVQILEERGHE
EEECCCCCCHHHHHHHHHHCCCCEEHHCCCCCCCEEEEEEHHHHCCCCEEEEECCCCCC
>Mature Secondary Structure
MKIIRYTAWLAHLLLIAGCSEPTKLERDTLPRVKVAQAGEKVSDKLFFPAVANAAERSHL
CCEEHHHHHHHHHHHHHCCCCCCCCCHHCCCCCHHHHCCCHHHHCEECHHHHHHHHHCCE
SFRVAGEISKFHVKEGARVKQGDILAEIEPTDYRLAVDNAQARFSVIDSQYRRSQPLVEK
EEEEECCCCEEECCCCCEEECCCEEEEECCCCEEEEECCCCHHHHHHHHHHHHCCCHHHH
GLLAKSQFDEIAAQRQIARAELELAKLRLSFTQLRAPMDGIISRVSAEQFESVQVGQQIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
NIHNIDSVEVLIQLPDRLYATQPTASELAKIETVVRVPSGQVYPARIKEFTTEPDPATGT
HHCCCCCEEEEEECCHHHHCCCCCHHHHHHHHHHEECCCCCCCHHHHHHCCCCCCCCCCE
FTVTLSLPMPEQELILDGMAVEVSAKGQHVGLNPLNTISIPIEAIFNADGDELDKTAQYV
EEEEEECCCCHHHHHCCCEEEEEECCCCEECCCCCCEEEEEEEEEECCCCHHHHCCEEEE
WLLNNDNTVSKRQVRLAKASRSHVQVSEGINAGDRLVVAGVARLRDGMKVQILEERGHE
EEECCCCCCHHHHHHHHHHCCCCEEHHCCCCCCCEEEEEEHHHHCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]