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The map label for this gene is rraA

Identifier: 147674928

GI number: 147674928

Start: 2393486

End: 2394001

Strand: Reverse

Name: rraA

Synonym: VC0395_A2245

Alternate gene names: 147674928

Gene position: 2394001-2393486 (Counterclockwise)

Preceding gene: 147675764

Following gene: 147675135

Centisome position: 79.16

GC content: 50.0

Gene sequence:

>516_bases
ATGGAATACAATACTTCTGCGCTGTGTGATATCTATCTCGACCAAGTCGATGTCGTGGAGCCTATGTTCAGCAACTTTGG
TGGCTGTGCTTCGTTTGCCGGTCAAATCACCACGATTAAGTGCTATGAAGATAATGGCTTGATCCGTGAAACCCTTGAGC
AAGATGGTCTTGGCCGTATTTTGCTGATTGACGGTGGCGGCTCGCTGCGCCGTGCATTAATTGATGCAGAATTGGCGGCT
CTAGCGGAAGAAAATGAGTGGGAAGGCATTGTGGTGTATGGCAGTGTCCGTGAAGTGGATGAATTGGAAGAGATGAGCAT
CGGTATTCAGGCGATTGCTTCTATTCCTGTCGGCGCAACCTCGCAAGGCATCGGTGAAGTGGACATTCCAGTCAACTTTG
GCGGCGTCACCTTCCTACCAGAAGATTATCTGTATGCCGACAATACTGGCATCATCATCTCGCAAGAGCCGCTGAGCGCG
GATCTGGGCGAAGAAGAGGAAGATGAGTTGCTGTAA

Upstream 100 bases:

>100_bases
TCATTGCCCAAACTCTGACAAGTTAATTTGCACTCTGTCATTGCAATGACTCAATCACTCTATATACTCGTTGGAAGACT
TTCGCTAAGAGAACAAAGCT

Downstream 100 bases:

>100_bases
GCGAGCTCTCGCACTCTAAGAATTGAAAAAGCCGATGTCGTTGATATCGGCTTTTTTCATGCATTCTCTATTGGCTTGTA
ACGAGCTTAATCCAAATCAG

Product: ribonuclease activity regulator protein RraA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 171; Mature: 171

Protein sequence:

>171_residues
MEYNTSALCDIYLDQVDVVEPMFSNFGGCASFAGQITTIKCYEDNGLIRETLEQDGLGRILLIDGGGSLRRALIDAELAA
LAEENEWEGIVVYGSVREVDELEEMSIGIQAIASIPVGATSQGIGEVDIPVNFGGVTFLPEDYLYADNTGIIISQEPLSA
DLGEEEEDELL

Sequences:

>Translated_171_residues
MEYNTSALCDIYLDQVDVVEPMFSNFGGCASFAGQITTIKCYEDNGLIRETLEQDGLGRILLIDGGGSLRRALIDAELAA
LAEENEWEGIVVYGSVREVDELEEMSIGIQAIASIPVGATSQGIGEVDIPVNFGGVTFLPEDYLYADNTGIIISQEPLSA
DLGEEEEDELL
>Mature_171_residues
MEYNTSALCDIYLDQVDVVEPMFSNFGGCASFAGQITTIKCYEDNGLIRETLEQDGLGRILLIDGGGSLRRALIDAELAA
LAEENEWEGIVVYGSVREVDELEEMSIGIQAIASIPVGATSQGIGEVDIPVNFGGVTFLPEDYLYADNTGIIISQEPLSA
DLGEEEEDELL

Specific function: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities

COG id: COG0684

COG function: function code H; Demethylmenaquinone methyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RraA family

Homologues:

Organism=Escherichia coli, GI1790364, Length=158, Percent_Identity=68.9873417721519, Blast_Score=236, Evalue=9e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RRAA_VIBCH (Q9KNQ9)

Other databases:

- EMBL:   AE003852
- PIR:   B82049
- RefSeq:   NP_232300.1
- ProteinModelPortal:   Q9KNQ9
- SMR:   Q9KNQ9
- GeneID:   2615500
- GenomeReviews:   AE003852_GR
- KEGG:   vch:VC2672
- TIGR:   VC_2672
- HOGENOM:   HBG668175
- OMA:   QNEWEGI
- ProtClustDB:   PRK09372
- HAMAP:   MF_00471
- InterPro:   IPR005493
- InterPro:   IPR014339
- InterPro:   IPR010203
- Gene3D:   G3DSA:3.50.30.40
- TIGRFAMs:   TIGR01935
- TIGRFAMs:   TIGR02998

Pfam domain/function: PF03737 Methyltransf_6; SSF89562 RNaseE_inh/diMeMenaQ_MeTrfase

EC number: NA

Molecular weight: Translated: 18445; Mature: 18445

Theoretical pI: Translated: 3.39; Mature: 3.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYNTSALCDIYLDQVDVVEPMFSNFGGCASFAGQITTIKCYEDNGLIRETLEQDGLGRI
CCCCCCEEEEEECCHHHHHHHHHHCCCCHHHHCCCEEEEEEECCCCHHHHHHHHCCCCEE
LLIDGGGSLRRALIDAELAALAEENEWEGIVVYGSVREVDELEEMSIGIQAIASIPVGAT
EEEECCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHEECCCCCCC
SQGIGEVDIPVNFGGVTFLPEDYLYADNTGIIISQEPLSADLGEEEEDELL
CCCCCEEEEEEECCCEEECCCCCEEECCCEEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MEYNTSALCDIYLDQVDVVEPMFSNFGGCASFAGQITTIKCYEDNGLIRETLEQDGLGRI
CCCCCCEEEEEECCHHHHHHHHHHCCCCHHHHCCCEEEEEEECCCCHHHHHHHHCCCCEE
LLIDGGGSLRRALIDAELAALAEENEWEGIVVYGSVREVDELEEMSIGIQAIASIPVGAT
EEEECCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHEECCCCCCC
SQGIGEVDIPVNFGGVTFLPEDYLYADNTGIIISQEPLSADLGEEEEDELL
CCCCCEEEEEEECCCEEECCCCCEEECCCEEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301