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The map label for this gene is htpG

Identifier: 147674825

GI number: 147674825

Start: 538977

End: 540884

Strand: Direct

Name: htpG

Synonym: VC0395_A0506

Alternate gene names: 147674825

Gene position: 538977-540884 (Clockwise)

Preceding gene: 147674558

Following gene: 147673458

Centisome position: 17.82

GC content: 45.75

Gene sequence:

>1908_bases
ATGAGCGAGACTGCAACCACTAATAAAGAAACGCGTGGTTTTCAATCGGAAGTTAAACAACTGCTGCACCTGATGATTCA
CTCTTTGTACTCCAACAAAGAAATTTTCCTGCGTGAGTTGATTTCTAACGCCTCCGATGCCGTTGATAAGTTGCGTTTTC
AAGCGCTTTCTCATCCTGATCTCTATCAGGGCGACGCTGAATTAGGCGTAAAACTCTCTTTTGATAAAGACAAAAATACG
TTGACCATTTCGGATAACGGGATCGGTATGACCCGTGATGAAGTGATCGAAAACTTAGGTACGATTGCTAAATCGGGTAC
GGCTGAATTCTTCTCAAAACTTTCTCAAGAGCAGTCTAAAAACTCGCAGCTCATTGGTCAGTTTGGGGTGGGTTTTTACT
CGGCTTTCATCGTGGCGGATGCGGTGACGGTGCGGACTCGCGCTGCAGGTAGTGCACCAGCAGATGCAGTACAGTGGTAC
TCAAAAGGTGAGGGCGAGTACACGGTTGAAACTATCAATAAAGAGTCTCGTGGTACAGACATCATTTTGCATCTGCGTGA
AGAAGGTAAAGAGTTTTTGTCCGAATGGCGTTTGCGCGATGTGATTTCCAAATACTCTGATCACATCGGTATTCCTGTCT
ATATCCAAACCTCAGTGATGGATGAAGAAGGGAAAGCGACAGAAGAAACCAAATGGGAGCAGATCAACAAGGCTCAAGCT
CTGTGGACGCGTGCTAAATCGGAAGTTACCGATGAGGAATATAAAGAGTTCTACAAGCATGTATCACACGATTTTGCTGA
TCCACTCGTGTGGAGTCATAACAAAGTCGAAGGTAAAAATGACTACACCAGCTTACTTTACATTCCTGCTAAAGCGCCTT
GGGATCTGTTCAATCGTGAACATAAGCATGGTTTAAAACTGTATGTGCAACGCGTCTTTATTATGGATGATGCGGCGCAA
TTCATGCCTTCTTATCTGAGATTCGTACGTGGTTTGATTGACTCAAACGATCTGCCGCTCAACGTATCGCGTGAAATTCT
GCAAGATAACAAGATCACTCAGTCACTGCGCCAAGCTTGTACTAAGCGCGTATTGACTATGCTTGAGCGCATGGCGAGCA
ATGATGCTGACAATTACCAGAAATTCTGGAAAGAGTTTGGCTTGGTGATGAAAGAAGGTCCGGCAGAAGATTTTGCTAAC
CGCGAGAAAATCGCTAGCTTGCTGCGTTTTGCCTCTACTCATATCGATTCGGCAGAGCAAACCATCAGCCTTGCTTCTTA
TGTCGAGCGCATGAAAGAAGGTCAAGACAAGATCTACTATCTGACGGCAGACAGCTATACCGCTGCGAAAAACAGCCCAC
ACTTGGAGCAGTTTAAGTCAAAAGGGATTGAAGTCATTCTGATGTTTGATCGCATTGACGAATGGTTGATGAATTATTTG
CCAGAGTTTGAGGGTAAAGCGTTCCAGTCCATCACCAAAGCAGGCTTGGATCTCAGCCAGTTCGAAGATGAAGCCGAAAA
AGAGAAACATAAAGAGACGGAAGAGCAATTTAAGTCTGTGGTTGAACGCCTCAAAGGCTATTTAGGTAGCCGAGTGAAAG
AGGTTCGTACCACATTCAAACTGGCTAACACACCAGCAGTCGTGGTGACCGATGATTATGAAATGGGTACCCAAATGGCG
AAACTATTGGCCGCAGCCGGCCAGCCTGTGCCTGAAGTGAAGTACATCCTTGAAGTTAACCCTGAACATGCTTTGGTAAA
ACGCATGGCGGATGAAGCGGATGAGCAAACTTTTGGCCGTTGGGCGGAAGTGCTACTGGGTCAAGCTATGCTTGCCGAAC
GTGGCTCGATGGAAGATCCATCACAATTCTTAGGTGCAGTAAACCAACTGCTTGCACCTAGCCACTAA

Upstream 100 bases:

>100_bases
TTGAATTTACATTTTTTGTCCATATCTCACTTGCACATCAAGGTAATTCCATTGAGTCTCAATGGATCAATTGTTTGAAA
CAGAAGTAAACGGAGCGATT

Downstream 100 bases:

>100_bases
GTCCTTGCTATCGCATCTTAAGCCCGCTTCGGCGGGCTTTTTTCTGCCTTTGAGCTATCGAAGGACGGATTAGTGACTAA
ACAGGTGAATGGCTGTTTTG

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G

Number of amino acids: Translated: 635; Mature: 634

Protein sequence:

>635_residues
MSETATTNKETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAVDKLRFQALSHPDLYQGDAELGVKLSFDKDKNT
LTISDNGIGMTRDEVIENLGTIAKSGTAEFFSKLSQEQSKNSQLIGQFGVGFYSAFIVADAVTVRTRAAGSAPADAVQWY
SKGEGEYTVETINKESRGTDIILHLREEGKEFLSEWRLRDVISKYSDHIGIPVYIQTSVMDEEGKATEETKWEQINKAQA
LWTRAKSEVTDEEYKEFYKHVSHDFADPLVWSHNKVEGKNDYTSLLYIPAKAPWDLFNREHKHGLKLYVQRVFIMDDAAQ
FMPSYLRFVRGLIDSNDLPLNVSREILQDNKITQSLRQACTKRVLTMLERMASNDADNYQKFWKEFGLVMKEGPAEDFAN
REKIASLLRFASTHIDSAEQTISLASYVERMKEGQDKIYYLTADSYTAAKNSPHLEQFKSKGIEVILMFDRIDEWLMNYL
PEFEGKAFQSITKAGLDLSQFEDEAEKEKHKETEEQFKSVVERLKGYLGSRVKEVRTTFKLANTPAVVVTDDYEMGTQMA
KLLAAAGQPVPEVKYILEVNPEHALVKRMADEADEQTFGRWAEVLLGQAMLAERGSMEDPSQFLGAVNQLLAPSH

Sequences:

>Translated_635_residues
MSETATTNKETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAVDKLRFQALSHPDLYQGDAELGVKLSFDKDKNT
LTISDNGIGMTRDEVIENLGTIAKSGTAEFFSKLSQEQSKNSQLIGQFGVGFYSAFIVADAVTVRTRAAGSAPADAVQWY
SKGEGEYTVETINKESRGTDIILHLREEGKEFLSEWRLRDVISKYSDHIGIPVYIQTSVMDEEGKATEETKWEQINKAQA
LWTRAKSEVTDEEYKEFYKHVSHDFADPLVWSHNKVEGKNDYTSLLYIPAKAPWDLFNREHKHGLKLYVQRVFIMDDAAQ
FMPSYLRFVRGLIDSNDLPLNVSREILQDNKITQSLRQACTKRVLTMLERMASNDADNYQKFWKEFGLVMKEGPAEDFAN
REKIASLLRFASTHIDSAEQTISLASYVERMKEGQDKIYYLTADSYTAAKNSPHLEQFKSKGIEVILMFDRIDEWLMNYL
PEFEGKAFQSITKAGLDLSQFEDEAEKEKHKETEEQFKSVVERLKGYLGSRVKEVRTTFKLANTPAVVVTDDYEMGTQMA
KLLAAAGQPVPEVKYILEVNPEHALVKRMADEADEQTFGRWAEVLLGQAMLAERGSMEDPSQFLGAVNQLLAPSH
>Mature_634_residues
SETATTNKETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAVDKLRFQALSHPDLYQGDAELGVKLSFDKDKNTL
TISDNGIGMTRDEVIENLGTIAKSGTAEFFSKLSQEQSKNSQLIGQFGVGFYSAFIVADAVTVRTRAAGSAPADAVQWYS
KGEGEYTVETINKESRGTDIILHLREEGKEFLSEWRLRDVISKYSDHIGIPVYIQTSVMDEEGKATEETKWEQINKAQAL
WTRAKSEVTDEEYKEFYKHVSHDFADPLVWSHNKVEGKNDYTSLLYIPAKAPWDLFNREHKHGLKLYVQRVFIMDDAAQF
MPSYLRFVRGLIDSNDLPLNVSREILQDNKITQSLRQACTKRVLTMLERMASNDADNYQKFWKEFGLVMKEGPAEDFANR
EKIASLLRFASTHIDSAEQTISLASYVERMKEGQDKIYYLTADSYTAAKNSPHLEQFKSKGIEVILMFDRIDEWLMNYLP
EFEGKAFQSITKAGLDLSQFEDEAEKEKHKETEEQFKSVVERLKGYLGSRVKEVRTTFKLANTPAVVVTDDYEMGTQMAK
LLAAAGQPVPEVKYILEVNPEHALVKRMADEADEQTFGRWAEVLLGQAMLAERGSMEDPSQFLGAVNQLLAPSH

Specific function: Molecular chaperone. Has ATPase activity

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family

Homologues:

Organism=Homo sapiens, GI4507677, Length=683, Percent_Identity=36.6032210834553, Blast_Score=426, Evalue=1e-119,
Organism=Homo sapiens, GI20149594, Length=670, Percent_Identity=37.3134328358209, Blast_Score=404, Evalue=1e-112,
Organism=Homo sapiens, GI155722983, Length=640, Percent_Identity=37.65625, Blast_Score=390, Evalue=1e-108,
Organism=Homo sapiens, GI154146191, Length=410, Percent_Identity=37.5609756097561, Blast_Score=266, Evalue=5e-71,
Organism=Homo sapiens, GI153792590, Length=410, Percent_Identity=37.5609756097561, Blast_Score=264, Evalue=2e-70,
Organism=Escherichia coli, GI1786679, Length=624, Percent_Identity=69.7115384615385, Blast_Score=915, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=672, Percent_Identity=37.202380952381, Blast_Score=448, Evalue=1e-126,
Organism=Caenorhabditis elegans, GI17542208, Length=673, Percent_Identity=37.592867756315, Blast_Score=424, Evalue=1e-119,
Organism=Caenorhabditis elegans, GI115535205, Length=643, Percent_Identity=34.0590979782271, Blast_Score=330, Evalue=1e-90,
Organism=Caenorhabditis elegans, GI115535167, Length=427, Percent_Identity=36.2997658079625, Blast_Score=267, Evalue=2e-71,
Organism=Saccharomyces cerevisiae, GI6323840, Length=679, Percent_Identity=37.260677466863, Blast_Score=424, Evalue=1e-119,
Organism=Saccharomyces cerevisiae, GI6325016, Length=209, Percent_Identity=44.0191387559809, Blast_Score=174, Evalue=4e-44,
Organism=Drosophila melanogaster, GI17647529, Length=641, Percent_Identity=37.9095163806552, Blast_Score=447, Evalue=1e-126,
Organism=Drosophila melanogaster, GI21357739, Length=681, Percent_Identity=38.1791483113069, Blast_Score=418, Evalue=1e-117,
Organism=Drosophila melanogaster, GI24586016, Length=651, Percent_Identity=33.026113671275, Blast_Score=348, Evalue=8e-96,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): HTPG_VIBC3 (A5F2T9)

Other databases:

- EMBL:   CP000627
- EMBL:   CP001235
- ProteinModelPortal:   A5F2T9
- SMR:   A5F2T9
- STRING:   A5F2T9
- GenomeReviews:   CP000627_GR
- GenomeReviews:   CP001235_GR
- KEGG:   vco:VC0395_A0506
- eggNOG:   COG0326
- HOGENOM:   HBG631012
- OMA:   AIYYITA
- ProtClustDB:   PRK05218
- BioCyc:   VCHO345073:VC0395_A0506-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00505
- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568
- Gene3D:   G3DSA:3.30.565.10
- PANTHER:   PTHR11528
- PIRSF:   PIRSF002583
- PRINTS:   PR00775
- SMART:   SM00387

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90; SSF55874 ATP_bd_ATPase; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: NA

Molecular weight: Translated: 72198; Mature: 72067

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSETATTNKETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAVDKLRFQALSHPD
CCCCCCCCHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LYQGDAELGVKLSFDKDKNTLTISDNGIGMTRDEVIENLGTIAKSGTAEFFSKLSQEQSK
CCCCCCCCCEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
NSQLIGQFGVGFYSAFIVADAVTVRTRAAGSAPADAVQWYSKGEGEYTVETINKESRGTD
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCE
IILHLREEGKEFLSEWRLRDVISKYSDHIGIPVYIQTSVMDEEGKATEETKWEQINKAQA
EEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHH
LWTRAKSEVTDEEYKEFYKHVSHDFADPLVWSHNKVEGKNDYTSLLYIPAKAPWDLFNRE
HHHHHHHCCCHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCEEEEEECCCCCHHHHCCH
HKHGLKLYVQRVFIMDDAAQFMPSYLRFVRGLIDSNDLPLNVSREILQDNKITQSLRQAC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHHH
TKRVLTMLERMASNDADNYQKFWKEFGLVMKEGPAEDFANREKIASLLRFASTHIDSAEQ
HHHHHHHHHHHHCCCCHHHHHHHHHHCCHHCCCCCHHHCCHHHHHHHHHHHHHHCCHHHH
TISLASYVERMKEGQDKIYYLTADSYTAAKNSPHLEQFKSKGIEVILMFDRIDEWLMNYL
HHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHCCCEEEEEHHHHHHHHHHHC
PEFEGKAFQSITKAGLDLSQFEDEAEKEKHKETEEQFKSVVERLKGYLGSRVKEVRTTFK
CCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LANTPAVVVTDDYEMGTQMAKLLAAAGQPVPEVKYILEVNPEHALVKRMADEADEQTFGR
CCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHH
WAEVLLGQAMLAERGSMEDPSQFLGAVNQLLAPSH
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SETATTNKETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAVDKLRFQALSHPD
CCCCCCCHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LYQGDAELGVKLSFDKDKNTLTISDNGIGMTRDEVIENLGTIAKSGTAEFFSKLSQEQSK
CCCCCCCCCEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
NSQLIGQFGVGFYSAFIVADAVTVRTRAAGSAPADAVQWYSKGEGEYTVETINKESRGTD
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCE
IILHLREEGKEFLSEWRLRDVISKYSDHIGIPVYIQTSVMDEEGKATEETKWEQINKAQA
EEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHH
LWTRAKSEVTDEEYKEFYKHVSHDFADPLVWSHNKVEGKNDYTSLLYIPAKAPWDLFNRE
HHHHHHHCCCHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCEEEEEECCCCCHHHHCCH
HKHGLKLYVQRVFIMDDAAQFMPSYLRFVRGLIDSNDLPLNVSREILQDNKITQSLRQAC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHHH
TKRVLTMLERMASNDADNYQKFWKEFGLVMKEGPAEDFANREKIASLLRFASTHIDSAEQ
HHHHHHHHHHHHCCCCHHHHHHHHHHCCHHCCCCCHHHCCHHHHHHHHHHHHHHCCHHHH
TISLASYVERMKEGQDKIYYLTADSYTAAKNSPHLEQFKSKGIEVILMFDRIDEWLMNYL
HHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHCCCEEEEEHHHHHHHHHHHC
PEFEGKAFQSITKAGLDLSQFEDEAEKEKHKETEEQFKSVVERLKGYLGSRVKEVRTTFK
CCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LANTPAVVVTDDYEMGTQMAKLLAAAGQPVPEVKYILEVNPEHALVKRMADEADEQTFGR
CCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHH
WAEVLLGQAMLAERGSMEDPSQFLGAVNQLLAPSH
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA