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The map label for this gene is dctM [H]

Identifier: 147674787

GI number: 147674787

Start: 1632105

End: 1633466

Strand: Reverse

Name: dctM [H]

Synonym: VC0395_A1517

Alternate gene names: 147674787

Gene position: 1633466-1632105 (Counterclockwise)

Preceding gene: 147675606

Following gene: 147675226

Centisome position: 54.02

GC content: 50.37

Gene sequence:

>1362_bases
ATGGCCGTTGCACTGTTATTTATTCTGGTTATCGGCATGATGATTGTTGGCGTGCCGATTGCTATCTCGCTGGGCTTATC
CAGTATTTTGTTCCTATTGTGGCACTCGGATGCCTCTTTAGCTTCGGTTGCACAAACCCTGTTTAACGCGTTTGCTGGCC
ACTACACTTTATTGGCGATCCCGTTTTTTATTCTCGCCTCAACGTTTATGTCTACTGGCGGTGTGGCTAAACGAATCATC
CGTTTTGCGATTGCTATGGTTGGCTGGTTCCGCGGCGGTTTAGCGATTGCTTCTGTGGTCGCCTGTATGATGTTTGCGGC
GCTCTCGGGCTCATCTCCGGCAACGGTGGTTGCCATCGGCAGTATCGTGATTGCGGGCATGGTCAAAAACGGCTACAGCA
AAGAGTTTGCGGCGGGGGTGATTTGTAACGCAGGAACCTTGGGTATTTTGATCCCCCCTTCGATTGTGATGGTGGTGTAC
TCAGCGGCGACCAACGTTTCGGTTGGCCGCATGTTCTTAGGTGGTGTTGTCCCAGGCTTATTGGCTGGTCTAATGTTGAT
CATCGCGATTTACATTACCGCGCGGATAAAAAATCTACCCAAGCAGCCCTTTGTTGGCTGGAAAGAAGCGCTGAAAGCAG
CCAAAGAGGCAAGCTGGGGCTTATTGTTGGTGGTGATTATTCTCGGTGGGATCTACGGTGGGATCTTTACCCCAACAGAA
GCGGCAGCAGTGGCGGCGGTGTACTCCTTTTTTATCGCCAACTTCATCTATCGTGACATGGGGCCGTTTGCGGATAAGAC
CAATACCAAACCGGTACTAGTCAAAGTAGTGGAAACCTTTGTCCACAAAGACACCAAAGCGACCTTGTATGATGCAGGTA
AGCTGACCATCATGCTGATGTTCATCATTGCTAACGCGCTTATCTTAAAACATGTACTCACCGAAGAGCGCATCCCGCAG
ATGATCACTGAATCCATGCTGTCTGCTGGGCTTGGGCCAATTACCTTCTTGATTGTCGTGAACCTGATCTTGTTGGTGGG
TGGTCAGTTTATGGAGCCATCGGGTCTTCTGGTTATCGTCGCTCCCTTGGTATTCCCGATTGCGATTGCATTGGGCATCG
ACCCTATCCATCTCGGCATCATGATGGTAGTGAACATGGAGATTGGCATGATCACGCCGCCCGTCGGCTTAAACCTGTTT
GTGACCTCTGGGGTAGCCAAGATGTCGATGATGAATGTGGTTAAAGCTGCACTGCCTTGGGTGGGCGTCATGTTCCTCTT
CCTCATTATTGTCACTTATGTGCCTTGGGTATCCACTTGGTTACCGACACTCTTGATGGGGCCGGAAATCATCACTCGCT
AG

Upstream 100 bases:

>100_bases
CGGTCATGAAGCCGAAGAAGATTTAGAAGCACTGAAAGCGGAGCTTTCAGAAGCGGGTGAGGCAATGATGCCTAAGACTC
AAGGCAAGGAGAAGTAAGCC

Downstream 100 bases:

>100_bases
CGCTTAATTCGATAATGCTTACGTTTGCCAAATAACGACAAGCCCTTCGCATGCGAAGGGCTTGGTTTTTTTATGCCGAC
CTTTAATCTGAGACCTAGAC

Product: C4-dicarboxylate transport protein

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 453; Mature: 452

Protein sequence:

>453_residues
MAVALLFILVIGMMIVGVPIAISLGLSSILFLLWHSDASLASVAQTLFNAFAGHYTLLAIPFFILASTFMSTGGVAKRII
RFAIAMVGWFRGGLAIASVVACMMFAALSGSSPATVVAIGSIVIAGMVKNGYSKEFAAGVICNAGTLGILIPPSIVMVVY
SAATNVSVGRMFLGGVVPGLLAGLMLIIAIYITARIKNLPKQPFVGWKEALKAAKEASWGLLLVVIILGGIYGGIFTPTE
AAAVAAVYSFFIANFIYRDMGPFADKTNTKPVLVKVVETFVHKDTKATLYDAGKLTIMLMFIIANALILKHVLTEERIPQ
MITESMLSAGLGPITFLIVVNLILLVGGQFMEPSGLLVIVAPLVFPIAIALGIDPIHLGIMMVVNMEIGMITPPVGLNLF
VTSGVAKMSMMNVVKAALPWVGVMFLFLIIVTYVPWVSTWLPTLLMGPEIITR

Sequences:

>Translated_453_residues
MAVALLFILVIGMMIVGVPIAISLGLSSILFLLWHSDASLASVAQTLFNAFAGHYTLLAIPFFILASTFMSTGGVAKRII
RFAIAMVGWFRGGLAIASVVACMMFAALSGSSPATVVAIGSIVIAGMVKNGYSKEFAAGVICNAGTLGILIPPSIVMVVY
SAATNVSVGRMFLGGVVPGLLAGLMLIIAIYITARIKNLPKQPFVGWKEALKAAKEASWGLLLVVIILGGIYGGIFTPTE
AAAVAAVYSFFIANFIYRDMGPFADKTNTKPVLVKVVETFVHKDTKATLYDAGKLTIMLMFIIANALILKHVLTEERIPQ
MITESMLSAGLGPITFLIVVNLILLVGGQFMEPSGLLVIVAPLVFPIAIALGIDPIHLGIMMVVNMEIGMITPPVGLNLF
VTSGVAKMSMMNVVKAALPWVGVMFLFLIIVTYVPWVSTWLPTLLMGPEIITR
>Mature_452_residues
AVALLFILVIGMMIVGVPIAISLGLSSILFLLWHSDASLASVAQTLFNAFAGHYTLLAIPFFILASTFMSTGGVAKRIIR
FAIAMVGWFRGGLAIASVVACMMFAALSGSSPATVVAIGSIVIAGMVKNGYSKEFAAGVICNAGTLGILIPPSIVMVVYS
AATNVSVGRMFLGGVVPGLLAGLMLIIAIYITARIKNLPKQPFVGWKEALKAAKEASWGLLLVVIILGGIYGGIFTPTEA
AAVAAVYSFFIANFIYRDMGPFADKTNTKPVLVKVVETFVHKDTKATLYDAGKLTIMLMFIIANALILKHVLTEERIPQM
ITESMLSAGLGPITFLIVVNLILLVGGQFMEPSGLLVIVAPLVFPIAIALGIDPIHLGIMMVVNMEIGMITPPVGLNLFV
TSGVAKMSMMNVVKAALPWVGVMFLFLIIVTYVPWVSTWLPTLLMGPEIITR

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=419, Percent_Identity=34.3675417661098, Blast_Score=213, Evalue=2e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 48082; Mature: 47951

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVALLFILVIGMMIVGVPIAISLGLSSILFLLWHSDASLASVAQTLFNAFAGHYTLLAI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
PFFILASTFMSTGGVAKRIIRFAIAMVGWFRGGLAIASVVACMMFAALSGSSPATVVAIG
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
SIVIAGMVKNGYSKEFAAGVICNAGTLGILIPPSIVMVVYSAATNVSVGRMFLGGVVPGL
HHHHHHHHHCCCCHHHHHCEEECCCCEEEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LAGLMLIIAIYITARIKNLPKQPFVGWKEALKAAKEASWGLLLVVIILGGIYGGIFTPTE
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHH
AAAVAAVYSFFIANFIYRDMGPFADKTNTKPVLVKVVETFVHKDTKATLYDAGKLTIMLM
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHCCCHHHHHHHH
FIIANALILKHVLTEERIPQMITESMLSAGLGPITFLIVVNLILLVGGQFMEPSGLLVIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHEEH
APLVFPIAIALGIDPIHLGIMMVVNMEIGMITPPVGLNLFVTSGVAKMSMMNVVKAALPW
HHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
VGVMFLFLIIVTYVPWVSTWLPTLLMGPEIITR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCC
>Mature Secondary Structure 
AVALLFILVIGMMIVGVPIAISLGLSSILFLLWHSDASLASVAQTLFNAFAGHYTLLAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
PFFILASTFMSTGGVAKRIIRFAIAMVGWFRGGLAIASVVACMMFAALSGSSPATVVAIG
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
SIVIAGMVKNGYSKEFAAGVICNAGTLGILIPPSIVMVVYSAATNVSVGRMFLGGVVPGL
HHHHHHHHHCCCCHHHHHCEEECCCCEEEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LAGLMLIIAIYITARIKNLPKQPFVGWKEALKAAKEASWGLLLVVIILGGIYGGIFTPTE
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHH
AAAVAAVYSFFIANFIYRDMGPFADKTNTKPVLVKVVETFVHKDTKATLYDAGKLTIMLM
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHCCCHHHHHHHH
FIIANALILKHVLTEERIPQMITESMLSAGLGPITFLIVVNLILLVGGQFMEPSGLLVIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHEEH
APLVFPIAIALGIDPIHLGIMMVVNMEIGMITPPVGLNLFVTSGVAKMSMMNVVKAALPW
HHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
VGVMFLFLIIVTYVPWVSTWLPTLLMGPEIITR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]