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The map label for this gene is dnaQ [H]

Identifier: 147674786

GI number: 147674786

Start: 1941367

End: 1942110

Strand: Reverse

Name: dnaQ [H]

Synonym: VC0395_A1825

Alternate gene names: 147674786

Gene position: 1942110-1941367 (Counterclockwise)

Preceding gene: 147673588

Following gene: 147674375

Centisome position: 64.22

GC content: 47.58

Gene sequence:

>744_bases
ATGAATACTAGCAACAATGCAGAATACCAACGCATCGTGGTGCTCGATACCGAAACCACGGGTATGAACCGCGAAGGCGG
CCCCCATTACGAGGGACATCGAATTATTGAGATCGGTGCAGTTGAAATTATCAACCGTAAACTCACCGGACGGCATTTTC
ACGTCTACTTAAAACCAGATCGCGATATTCAATTAGAGGCGATTGAAGTTCACGGTATTACCGATGAGTTTCTAAAAGAT
AAGCCCGAGTACAAAGATGTCCATGAGGAGTTTGTAGACTTCATCAAAGGGGCCGAGCTGGTTGCCCACAATGCACCGTT
TGACGTCGGCTTTATGGATTACGAGTTTGCTAAACTCGGTGGTGCGATCGGTAAAACCAGCGATTTTTGCAAAGTGACCG
ATACTTTGGCGATGGCCAAGCGGATTTTCCCCGGTAAACGCAATAACTTGGATATCTTGTGTGAGCGTTACGGCATTGAT
AACTCACACCGAACCCTGCACGGCGCTTTGCTCGATGCGGAGATTCTAGCCGACGTTTATCTATTGATGACCGGTGGGCA
GACTTCACTGCAATTTTCATCGGTCACGCAAAATAGTGGGGAATTGAGCGCAGAATCGTTAAAACGTGCTCGTTCAGAGC
GAAAAGCGTTAAAGGTTTTAGCGGCTAGCGCCGATGAACTACAAGCACATCAAGATCGTTTGGACATAGTGGCCAAAAGT
GGCACTTGCCTATGGCGTAGTTAG

Upstream 100 bases:

>100_bases
CCGAGGCAAGAACCATCCGTGAAAATTTCCACCTGTTTGTTCATGATTTGATACTATTGGGTCACGCAAAGAATTGGCAT
AGTCTGACATAGATATCCTG

Downstream 100 bases:

>100_bases
GAGAAGTTATGTTGAGGATTCTCGCGGCGATAGTGGGATGTTTGATCAGTTTGAGTAGTCTAGCGGCACAACAATCTAGC
ATGTCGCTGCTCGATAACCG

Product: DNA polymerase III subunit epsilon

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MNTSNNAEYQRIVVLDTETTGMNREGGPHYEGHRIIEIGAVEIINRKLTGRHFHVYLKPDRDIQLEAIEVHGITDEFLKD
KPEYKDVHEEFVDFIKGAELVAHNAPFDVGFMDYEFAKLGGAIGKTSDFCKVTDTLAMAKRIFPGKRNNLDILCERYGID
NSHRTLHGALLDAEILADVYLLMTGGQTSLQFSSVTQNSGELSAESLKRARSERKALKVLAASADELQAHQDRLDIVAKS
GTCLWRS

Sequences:

>Translated_247_residues
MNTSNNAEYQRIVVLDTETTGMNREGGPHYEGHRIIEIGAVEIINRKLTGRHFHVYLKPDRDIQLEAIEVHGITDEFLKD
KPEYKDVHEEFVDFIKGAELVAHNAPFDVGFMDYEFAKLGGAIGKTSDFCKVTDTLAMAKRIFPGKRNNLDILCERYGID
NSHRTLHGALLDAEILADVYLLMTGGQTSLQFSSVTQNSGELSAESLKRARSERKALKVLAASADELQAHQDRLDIVAKS
GTCLWRS
>Mature_247_residues
MNTSNNAEYQRIVVLDTETTGMNREGGPHYEGHRIIEIGAVEIINRKLTGRHFHVYLKPDRDIQLEAIEVHGITDEFLKD
KPEYKDVHEEFVDFIKGAELVAHNAPFDVGFMDYEFAKLGGAIGKTSDFCKVTDTLAMAKRIFPGKRNNLDILCERYGID
NSHRTLHGALLDAEILADVYLLMTGGQTSLQFSSVTQNSGELSAESLKRARSERKALKVLAASADELQAHQDRLDIVAKS
GTCLWRS

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786409, Length=238, Percent_Identity=60.5042016806723, Blast_Score=302, Evalue=1e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006309
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 27637; Mature: 27637

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTSNNAEYQRIVVLDTETTGMNREGGPHYEGHRIIEIGAVEIINRKLTGRHFHVYLKPD
CCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCEEEEECHHHHHHHCCCCCEEEEEECCC
RDIQLEAIEVHGITDEFLKDKPEYKDVHEEFVDFIKGAELVAHNAPFDVGFMDYEFAKLG
CCEEEEEEEEECCCHHHHCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHC
GAIGKTSDFCKVTDTLAMAKRIFPGKRNNLDILCERYGIDNSHRTLHGALLDAEILADVY
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
LLMTGGQTSLQFSSVTQNSGELSAESLKRARSERKALKVLAASADELQAHQDRLDIVAKS
EEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEEECC
GTCLWRS
CEEEECC
>Mature Secondary Structure
MNTSNNAEYQRIVVLDTETTGMNREGGPHYEGHRIIEIGAVEIINRKLTGRHFHVYLKPD
CCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCEEEEECHHHHHHHCCCCCEEEEEECCC
RDIQLEAIEVHGITDEFLKDKPEYKDVHEEFVDFIKGAELVAHNAPFDVGFMDYEFAKLG
CCEEEEEEEEECCCHHHHCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHC
GAIGKTSDFCKVTDTLAMAKRIFPGKRNNLDILCERYGIDNSHRTLHGALLDAEILADVY
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
LLMTGGQTSLQFSSVTQNSGELSAESLKRARSERKALKVLAASADELQAHQDRLDIVAKS
EEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEEECC
GTCLWRS
CEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3023634; 6316347; 3540531; 9278503; 1575709 [H]