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The map label for this gene is uppP

Identifier: 147674526

GI number: 147674526

Start: 49650

End: 50453

Strand: Direct

Name: uppP

Synonym: VC0395_A0054

Alternate gene names: 147674526

Gene position: 49650-50453 (Clockwise)

Preceding gene: 147673898

Following gene: 147674770

Centisome position: 1.64

GC content: 45.77

Gene sequence:

>804_bases
ATGAGTTATTTTGAGTCGTTCATTCTGGCTTTAATTCAAGGCTTTACCGAGTTTTTACCGATTTCTAGCTCCGCACACCT
GATCTTGCCTTCGGCTATTTTAGGTTGGGAAGATCAAGGCTTGGCCTTTGATGTGGCGGTACACGTGGGAACGCTCGCCG
CGGTCGTGCTCTATTTTCGAAAAGAAGTGGTTTCGTTATTAAGTGCTTTTTTTGCTTCGATTTTTAAAGGTGATCGCAGC
AAAGAAGCCAAATTGGCGTGGTTGATCGTGCTGGCTACGATTCCGGCTTGTCTGTTCGGTTTTGTGATGAAAGATATTGT
TGAGCTCTATTTGCGCAGCGCTTGGGTTATCGCGACAACGACTATCGTGTTTGGCCTTTTACTCTGGTATGTCGATAAAC
ATGCAGAGCTCAAAGCCGACGAATATCAAGCGGATTGGAAAAAAGCGCTGTTTATTGGTTTGGCGCAGGCCGTGGCTATT
ATTCCTGGCACTTCACGCTCTGGTGCAACCATCACTGCTGCGCTCTATCTTGGCTTTACCCGTGAAGCGGCGGCGCGTTT
TTCATTCTTAATGTCGATTCCAATTATCGTATTGGCGGGCAGTTATCTCGGATTGAAACTGGTGACCAGTGGTGAACCCG
TACACAGCGGTTTCTTACTGACAGGCATCATCACTTCATTTATCAGTGCTTACATCTGTATTCACTTCTTCCTGAAGCTC
ATCTCTCGTATGGGCATGACCCCGTTTGTGATTTATCGCTTAGTGCTTGGTGTAGGCTTATTTGCGTTTTTATTAACTCA
ATAA

Upstream 100 bases:

>100_bases
GTGATGGTCGAACTGTTGAGCAGATTTGGCAACAAGCGCAGGATTTAGCATCACTCACCCCAGTACCGATCTGGTTTTCT
ATTAACGAGAAGAAACAATC

Downstream 100 bases:

>100_bases
TCACCTGCCAGCAAGCGCCTTTTCTAGGCTTTATGGTATAAATAGGCAGCATTCGAGCAAGTGACCAACGCCACGATTTT
GTGGCGTTGGTTTTGAAAGA

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MSYFESFILALIQGFTEFLPISSSAHLILPSAILGWEDQGLAFDVAVHVGTLAAVVLYFRKEVVSLLSAFFASIFKGDRS
KEAKLAWLIVLATIPACLFGFVMKDIVELYLRSAWVIATTTIVFGLLLWYVDKHAELKADEYQADWKKALFIGLAQAVAI
IPGTSRSGATITAALYLGFTREAAARFSFLMSIPIIVLAGSYLGLKLVTSGEPVHSGFLLTGIITSFISAYICIHFFLKL
ISRMGMTPFVIYRLVLGVGLFAFLLTQ

Sequences:

>Translated_267_residues
MSYFESFILALIQGFTEFLPISSSAHLILPSAILGWEDQGLAFDVAVHVGTLAAVVLYFRKEVVSLLSAFFASIFKGDRS
KEAKLAWLIVLATIPACLFGFVMKDIVELYLRSAWVIATTTIVFGLLLWYVDKHAELKADEYQADWKKALFIGLAQAVAI
IPGTSRSGATITAALYLGFTREAAARFSFLMSIPIIVLAGSYLGLKLVTSGEPVHSGFLLTGIITSFISAYICIHFFLKL
ISRMGMTPFVIYRLVLGVGLFAFLLTQ
>Mature_266_residues
SYFESFILALIQGFTEFLPISSSAHLILPSAILGWEDQGLAFDVAVHVGTLAAVVLYFRKEVVSLLSAFFASIFKGDRSK
EAKLAWLIVLATIPACLFGFVMKDIVELYLRSAWVIATTTIVFGLLLWYVDKHAELKADEYQADWKKALFIGLAQAVAII
PGTSRSGATITAALYLGFTREAAARFSFLMSIPIIVLAGSYLGLKLVTSGEPVHSGFLLTGIITSFISAYICIHFFLKLI
SRMGMTPFVIYRLVLGVGLFAFLLTQ

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=266, Percent_Identity=33.4586466165414, Blast_Score=132, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_VIBC3 (A5F9D4)

Other databases:

- EMBL:   CP000627
- EMBL:   CP001235
- ProteinModelPortal:   A5F9D4
- STRING:   A5F9D4
- GenomeReviews:   CP000627_GR
- GenomeReviews:   CP001235_GR
- KEGG:   vco:VC0395_A0054
- eggNOG:   COG1968
- HOGENOM:   HBG391969
- OMA:   HSMYWFV
- ProtClustDB:   PRK00281
- BioCyc:   VCHO345073:VC0395_A0054-MONOMER
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 29285; Mature: 29154

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x172c72c0)-; HASH(0x17cdccb4)-; HASH(0x17cdcdb0)-; HASH(0x17ce395c)-; HASH(0x17cdcd5c)-; HASH(0x17ce182c)-; HASH(0x17ce3b24)-; HASH(0x17cd1728)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYFESFILALIQGFTEFLPISSSAHLILPSAILGWEDQGLAFDVAVHVGTLAAVVLYFR
CCHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHH
KEVVSLLSAFFASIFKGDRSKEAKLAWLIVLATIPACLFGFVMKDIVELYLRSAWVIATT
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TIVFGLLLWYVDKHAELKADEYQADWKKALFIGLAQAVAIIPGTSRSGATITAALYLGFT
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHH
REAAARFSFLMSIPIIVLAGSYLGLKLVTSGEPVHSGFLLTGIITSFISAYICIHFFLKL
HHHHHHHHHHHHHHHHHHHCCHHCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ISRMGMTPFVIYRLVLGVGLFAFLLTQ
HHHCCCCHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure 
SYFESFILALIQGFTEFLPISSSAHLILPSAILGWEDQGLAFDVAVHVGTLAAVVLYFR
CHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHH
KEVVSLLSAFFASIFKGDRSKEAKLAWLIVLATIPACLFGFVMKDIVELYLRSAWVIATT
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TIVFGLLLWYVDKHAELKADEYQADWKKALFIGLAQAVAIIPGTSRSGATITAALYLGFT
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHH
REAAARFSFLMSIPIIVLAGSYLGLKLVTSGEPVHSGFLLTGIITSFISAYICIHFFLKL
HHHHHHHHHHHHHHHHHHHCCHHCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ISRMGMTPFVIYRLVLGVGLFAFLLTQ
HHHCCCCHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA