Click here to switch to the map view.

The map label for this gene is epsM [H]

Identifier: 147674283

GI number: 147674283

Start: 2451533

End: 2452033

Strand: Reverse

Name: epsM [H]

Synonym: VC0395_A2297

Alternate gene names: 147674283

Gene position: 2452033-2451533 (Counterclockwise)

Preceding gene: 147673681

Following gene: 147675210

Centisome position: 81.08

GC content: 52.89

Gene sequence:

>501_bases
ATGATGAAAGAATTATTGGCTCCTGTGCAGGCTTGGTGGCGAAGTGTCACCCCTCGTGAGCAAAAGATGGTAATGGGCAT
GGGCGCGCTGACGGTACTCGCTATCGCTTATTGGGGAATATGGCAGCCTTTGAGTGAGCGTACCGCCCAAGCTCAAGCAC
GATTACAAACCGAAAAACAGCTACTGAGTTGGGTTAGTGAAAACGCCAACGACATCGTAACGCTCCGTGCGCAAGGGGGC
AGTGATGCGCCAAGCGATCAACCACTCAATCAGGTGATCACTAACTCGACGCGTCAGTTCAATATTGAGCTGATCCGCGT
GCAGCCGCGCGGCGAAATGATGCAGGTCTGGATCCAACCGCTACCGTTTTCGCAATTGGTCTCATGGATTGCGTATTTGC
AAGAGCGCCAAGGGGTGAGCGTGGATGCGATTGATATTGACCGTGGTAAAGTGAACGGCGTTGTGGAAGTCAAACGTCTG
CAACTGAAGCGTGGAGGCTGA

Upstream 100 bases:

>100_bases
CACTCAGCTTGAGCAGTATTTTGCTGTTGAACAGGGGCAGCTCAATAAAAATGGCGAGCAAGTGTTTGGCGTGTTTGTGG
TGAAGCCCAAGTAAGGAGAA

Downstream 100 bases:

>100_bases
TATGAAGCGTGCTGTTGGCTATGGTCTGTTATTTTCCACAGTGTTAATGACCAGCGTGGTCGTGCATTTGCCTGCCCAAG
TGGCGCTTAGCCCGCTACCG

Product: cholera toxin secretion protein EpsM

Products: NA

Alternate protein names: Cholera toxin secretion protein epsM [H]

Number of amino acids: Translated: 166; Mature: 166

Protein sequence:

>166_residues
MMKELLAPVQAWWRSVTPREQKMVMGMGALTVLAIAYWGIWQPLSERTAQAQARLQTEKQLLSWVSENANDIVTLRAQGG
SDAPSDQPLNQVITNSTRQFNIELIRVQPRGEMMQVWIQPLPFSQLVSWIAYLQERQGVSVDAIDIDRGKVNGVVEVKRL
QLKRGG

Sequences:

>Translated_166_residues
MMKELLAPVQAWWRSVTPREQKMVMGMGALTVLAIAYWGIWQPLSERTAQAQARLQTEKQLLSWVSENANDIVTLRAQGG
SDAPSDQPLNQVITNSTRQFNIELIRVQPRGEMMQVWIQPLPFSQLVSWIAYLQERQGVSVDAIDIDRGKVNGVVEVKRL
QLKRGG
>Mature_166_residues
MMKELLAPVQAWWRSVTPREQKMVMGMGALTVLAIAYWGIWQPLSERTAQAQARLQTEKQLLSWVSENANDIVTLRAQGG
SDAPSDQPLNQVITNSTRQFNIELIRVQPRGEMMQVWIQPLPFSQLVSWIAYLQERQGVSVDAIDIDRGKVNGVVEVKRL
QLKRGG

Specific function: Required for secretion of cholera toxin through the outer membrane [H]

COG id: COG3149

COG function: function code U; Type II secretory pathway, component PulM

Gene ontology:

Cell location: Cell inner membrane (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP M family [H]

Homologues:

Organism=Escherichia coli, GI1789339, Length=150, Percent_Identity=32, Blast_Score=84, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007690
- InterPro:   IPR023229 [H]

Pfam domain/function: PF04612 GspM [H]

EC number: NA

Molecular weight: Translated: 18783; Mature: 18783

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKELLAPVQAWWRSVTPREQKMVMGMGALTVLAIAYWGIWQPLSERTAQAQARLQTEKQ
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLSWVSENANDIVTLRAQGGSDAPSDQPLNQVITNSTRQFNIELIRVQPRGEMMQVWIQP
HHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHCCCCCEEEEEEEEECCCCHHHHHHHCC
LPFSQLVSWIAYLQERQGVSVDAIDIDRGKVNGVVEVKRLQLKRGG
CCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MMKELLAPVQAWWRSVTPREQKMVMGMGALTVLAIAYWGIWQPLSERTAQAQARLQTEKQ
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLSWVSENANDIVTLRAQGGSDAPSDQPLNQVITNSTRQFNIELIRVQPRGEMMQVWIQP
HHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHCCCCCEEEEEEEEECCCCHHHHHHHCC
LPFSQLVSWIAYLQERQGVSVDAIDIDRGKVNGVVEVKRLQLKRGG
CCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8406031; 10952301 [H]