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The map label for this gene is udk [H]

Identifier: 147674003

GI number: 147674003

Start: 596530

End: 597189

Strand: Direct

Name: udk [H]

Synonym: VC0395_A0556

Alternate gene names: 147674003

Gene position: 596530-597189 (Clockwise)

Preceding gene: 147674192

Following gene: 147674400

Centisome position: 19.73

GC content: 48.18

Gene sequence:

>660_bases
ATGTTCGGGTGCATAACCATGTCTGAGAATAATCAATGTGTCATCGTCGGTATTGCTGGCGCTTCTGCTTCTGGTAAGAG
TCTCATTGCGAGCACGATTTATAATGAGCTACGCGCCAAAGTGGGTGACCATCAAATCGGTGTGATTACGGAAGATTGCT
ACTACAAAGATCAGAGCCATCTGAGCATGGAAGAACGTGTTAAAACCAACTACGACCACCCAAGTGCGCTAGACCACGAT
CTCCTTTGCCAACATTTGCAAATGTTGGCGCGTGGCGAAGCGGTTGAAGTGCCAGAATACAGCTACACTGAGCACACACG
TACCGAGCAAACCACCACCATGACGCCGAAGAAAGTGATCATTCTGGAAGGCATCCTGCTTCTGACTGATCCACGTCTTC
GTGATTTGATGCACGCGACCGTATTTATGGATACGCCGCTGGATATCTGCTTGCTGCGTCGTGTGAAGCGTGATGTACAA
GAGCGTGGTCGCACCATGGAATCTGTACTGAAGCAGTACCAAGAGACGGTACGCCCTATGTTTATGCAATTTATTGAGCC
GTCTAAACAGTACGCTGACATCATTGTGCCGCGTGGTGGTAAAAACCGTATCGCGATTGATGTTCTCAAAGCGCATATCG
CAAAATTGCTCAAATCGTAA

Upstream 100 bases:

>100_bases
ATCCATCCGACATTTATGTGGCTGTTTTTGCCTAATGCAAACTGGTATCTCGGTCACATTCTCCCTATAATCAGGCGGTT
TACCTTCATTCCTCACAACC

Downstream 100 bases:

>100_bases
TTTTGACCAGAGCTTTGCATCGCTTAGCTTTATTTTTCAAAGTAGAAGTGGCACTTTAAGTGCCACTTTCTTTTTCTCGT
CAAGCAAGGAAAAGCAGATG

Product: uridine kinase

Products: NA

Alternate protein names: Cytidine monophosphokinase; Uridine monophosphokinase [H]

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MFGCITMSENNQCVIVGIAGASASGKSLIASTIYNELRAKVGDHQIGVITEDCYYKDQSHLSMEERVKTNYDHPSALDHD
LLCQHLQMLARGEAVEVPEYSYTEHTRTEQTTTMTPKKVIILEGILLLTDPRLRDLMHATVFMDTPLDICLLRRVKRDVQ
ERGRTMESVLKQYQETVRPMFMQFIEPSKQYADIIVPRGGKNRIAIDVLKAHIAKLLKS

Sequences:

>Translated_219_residues
MFGCITMSENNQCVIVGIAGASASGKSLIASTIYNELRAKVGDHQIGVITEDCYYKDQSHLSMEERVKTNYDHPSALDHD
LLCQHLQMLARGEAVEVPEYSYTEHTRTEQTTTMTPKKVIILEGILLLTDPRLRDLMHATVFMDTPLDICLLRRVKRDVQ
ERGRTMESVLKQYQETVRPMFMQFIEPSKQYADIIVPRGGKNRIAIDVLKAHIAKLLKS
>Mature_219_residues
MFGCITMSENNQCVIVGIAGASASGKSLIASTIYNELRAKVGDHQIGVITEDCYYKDQSHLSMEERVKTNYDHPSALDHD
LLCQHLQMLARGEAVEVPEYSYTEHTRTEQTTTMTPKKVIILEGILLLTDPRLRDLMHATVFMDTPLDICLLRRVKRDVQ
ERGRTMESVLKQYQETVRPMFMQFIEPSKQYADIIVPRGGKNRIAIDVLKAHIAKLLKS

Specific function: Pyrimidine salvage pathway. [C]

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uridine kinase family [H]

Homologues:

Organism=Homo sapiens, GI18699734, Length=213, Percent_Identity=37.0892018779343, Blast_Score=165, Evalue=3e-41,
Organism=Homo sapiens, GI301129207, Length=208, Percent_Identity=37.9807692307692, Blast_Score=162, Evalue=3e-40,
Organism=Homo sapiens, GI57863312, Length=208, Percent_Identity=37.9807692307692, Blast_Score=162, Evalue=3e-40,
Organism=Homo sapiens, GI13899253, Length=215, Percent_Identity=37.6744186046512, Blast_Score=158, Evalue=4e-39,
Organism=Homo sapiens, GI209863022, Length=152, Percent_Identity=34.2105263157895, Blast_Score=99, Evalue=4e-21,
Organism=Escherichia coli, GI87082034, Length=210, Percent_Identity=74.7619047619048, Blast_Score=343, Evalue=6e-96,
Organism=Caenorhabditis elegans, GI17539894, Length=201, Percent_Identity=37.3134328358209, Blast_Score=150, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI17539892, Length=201, Percent_Identity=37.3134328358209, Blast_Score=150, Evalue=7e-37,
Organism=Caenorhabditis elegans, GI71981181, Length=214, Percent_Identity=34.5794392523364, Blast_Score=135, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6324339, Length=177, Percent_Identity=31.0734463276836, Blast_Score=110, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24649624, Length=226, Percent_Identity=37.1681415929204, Blast_Score=168, Evalue=3e-42,
Organism=Drosophila melanogaster, GI221458995, Length=226, Percent_Identity=37.1681415929204, Blast_Score=167, Evalue=7e-42,
Organism=Drosophila melanogaster, GI28573516, Length=201, Percent_Identity=40.7960199004975, Blast_Score=160, Evalue=7e-40,
Organism=Drosophila melanogaster, GI28573514, Length=201, Percent_Identity=40.7960199004975, Blast_Score=160, Evalue=7e-40,
Organism=Drosophila melanogaster, GI28573512, Length=201, Percent_Identity=40.7960199004975, Blast_Score=160, Evalue=7e-40,
Organism=Drosophila melanogaster, GI45550449, Length=201, Percent_Identity=40.7960199004975, Blast_Score=160, Evalue=8e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006083
- InterPro:   IPR000764 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.48 [H]

Molecular weight: Translated: 24881; Mature: 24881

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGCITMSENNQCVIVGIAGASASGKSLIASTIYNELRAKVGDHQIGVITEDCYYKDQSH
CCEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCHHCCCCHH
LSMEERVKTNYDHPSALDHDLLCQHLQMLARGEAVEVPEYSYTEHTRTEQTTTMTPKKVI
CCHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEH
ILEGILLLTDPRLRDLMHATVFMDTPLDICLLRRVKRDVQERGRTMESVLKQYQETVRPM
EECCCCEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
FMQFIEPSKQYADIIVPRGGKNRIAIDVLKAHIAKLLKS
HHHHHCCCHHHHEEEECCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFGCITMSENNQCVIVGIAGASASGKSLIASTIYNELRAKVGDHQIGVITEDCYYKDQSH
CCEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCHHCCCCHH
LSMEERVKTNYDHPSALDHDLLCQHLQMLARGEAVEVPEYSYTEHTRTEQTTTMTPKKVI
CCHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEH
ILEGILLLTDPRLRDLMHATVFMDTPLDICLLRRVKRDVQERGRTMESVLKQYQETVRPM
EECCCCEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
FMQFIEPSKQYADIIVPRGGKNRIAIDVLKAHIAKLLKS
HHHHHCCCHHHHEEEECCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]