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The map label for this gene is fabD [H]

Identifier: 147673966

GI number: 147673966

Start: 1728434

End: 1729372

Strand: Reverse

Name: fabD [H]

Synonym: VC0395_A1608

Alternate gene names: 147673966

Gene position: 1729372-1728434 (Counterclockwise)

Preceding gene: 147673193

Following gene: 147675453

Centisome position: 57.19

GC content: 48.99

Gene sequence:

>939_bases
ATGAAGGAAAGATTTATGAGTAAGTTTGCTATCGTATTTCCAGGTCAGGGCTCGCAAGCAGTAGGTATGCTGGCTGACCT
TGCCGAGCAGTATGCTGTGGTAAAACAAACATTCGCCGAAGCTTCAGAAGTGCTTGGTTACGATCTGTGGGCGCTGGTTC
AAGATGGCCCTGTGGAAGATCTCAACCAAACTTTCCGTACTCAACCTGCGTTGCTTGCCGCCTCTGTTGCGATTTGGCGT
GTATGGCAGCAACTGGGTCTTGAGCAACCTGCGGTTTTAGCTGGTCACAGCTTGGGTGAATATTCAGCACTGGTATGTGC
GGGCGTGATTGATTTTAAACAAGCGATCAAGCTGGTTGAGCTGCGTGGTCAATTGATGCAACAAGCGGTGCCTGCCGGTA
CGGGTGCAATGTACGCGATCATCGGTCTAGAAGATGAAGCGATTGCTAAAGCCTGTGCTGACGCGGCGCAAGGTGAAGTG
GTTTCTCCTGTAAACTTTAACTCACCAGGCCAAGTGGTTATTGCTGGTCAAAAAGATGCGGTTGAGCGTGCGGGCGTTCT
GTGTAAAGAAGCGGGCGCGAAACGTGCGCTGCCTCTGCCAGTTTCCGTACCATCACACTGCGCGTTGATGAAGCCTGCTG
CCGATGAATTGGCAAAAACTCTAGCAGAGCTTGAATTCAATGCACCACAAATTCCGGTCATCAATAACGTTGATGTTGTG
GCTGAAACGGATCCGGTAAAAATTAAAGATGCGTTGATTCGTCAACTCTATAGCCCAGTTCGTTGGACTGAATGCGTTGA
ACAAATGAGCGCACAAGGTGTCGAAAAGCTGATTGAAATGGGGCCGGGTAAAGTATTGACTGGTCTAACAAAACGTATTG
TAAAAACCCTAGAAGGTGTCGCAGTCAATGACGTGGCTTCTTTGGATGCGGTGAAATAA

Upstream 100 bases:

>100_bases
TTTTGGTGGTGGTTTCACATGGGGCTCTGCTCTGGTGAAGTTCTAAACGCACAATGAATTTTGACTTTAAGGAGTCCTAG
GACTCCTTATCCATTCTTAG

Downstream 100 bases:

>100_bases
CAACAGGAAGAAAACATGAGTCAATTCATGAATCTAGAGGGCAAAGTTGCTCTTGTGACTGGCGCAAGCCGCGGCATTGG
TAAAGCGATTGCTGAACTCT

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MKERFMSKFAIVFPGQGSQAVGMLADLAEQYAVVKQTFAEASEVLGYDLWALVQDGPVEDLNQTFRTQPALLAASVAIWR
VWQQLGLEQPAVLAGHSLGEYSALVCAGVIDFKQAIKLVELRGQLMQQAVPAGTGAMYAIIGLEDEAIAKACADAAQGEV
VSPVNFNSPGQVVIAGQKDAVERAGVLCKEAGAKRALPLPVSVPSHCALMKPAADELAKTLAELEFNAPQIPVINNVDVV
AETDPVKIKDALIRQLYSPVRWTECVEQMSAQGVEKLIEMGPGKVLTGLTKRIVKTLEGVAVNDVASLDAVK

Sequences:

>Translated_312_residues
MKERFMSKFAIVFPGQGSQAVGMLADLAEQYAVVKQTFAEASEVLGYDLWALVQDGPVEDLNQTFRTQPALLAASVAIWR
VWQQLGLEQPAVLAGHSLGEYSALVCAGVIDFKQAIKLVELRGQLMQQAVPAGTGAMYAIIGLEDEAIAKACADAAQGEV
VSPVNFNSPGQVVIAGQKDAVERAGVLCKEAGAKRALPLPVSVPSHCALMKPAADELAKTLAELEFNAPQIPVINNVDVV
AETDPVKIKDALIRQLYSPVRWTECVEQMSAQGVEKLIEMGPGKVLTGLTKRIVKTLEGVAVNDVASLDAVK
>Mature_312_residues
MKERFMSKFAIVFPGQGSQAVGMLADLAEQYAVVKQTFAEASEVLGYDLWALVQDGPVEDLNQTFRTQPALLAASVAIWR
VWQQLGLEQPAVLAGHSLGEYSALVCAGVIDFKQAIKLVELRGQLMQQAVPAGTGAMYAIIGLEDEAIAKACADAAQGEV
VSPVNFNSPGQVVIAGQKDAVERAGVLCKEAGAKRALPLPVSVPSHCALMKPAADELAKTLAELEFNAPQIPVINNVDVV
AETDPVKIKDALIRQLYSPVRWTECVEQMSAQGVEKLIEMGPGKVLTGLTKRIVKTLEGVAVNDVASLDAVK

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=299, Percent_Identity=33.4448160535117, Blast_Score=148, Evalue=6e-36,
Organism=Homo sapiens, GI27477045, Length=110, Percent_Identity=43.6363636363636, Blast_Score=79, Evalue=6e-15,
Organism=Escherichia coli, GI1787334, Length=305, Percent_Identity=71.1475409836066, Blast_Score=427, Evalue=1e-121,
Organism=Caenorhabditis elegans, GI71984332, Length=294, Percent_Identity=29.9319727891156, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17550940, Length=301, Percent_Identity=30.2325581395349, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24665753, Length=301, Percent_Identity=34.21926910299, Blast_Score=137, Evalue=1e-32,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 33218; Mature: 33218

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKERFMSKFAIVFPGQGSQAVGMLADLAEQYAVVKQTFAEASEVLGYDLWALVQDGPVED
CCCHHHHCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LNQTFRTQPALLAASVAIWRVWQQLGLEQPAVLAGHSLGEYSALVCAGVIDFKQAIKLVE
HHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
LRGQLMQQAVPAGTGAMYAIIGLEDEAIAKACADAAQGEVVSPVNFNSPGQVVIAGQKDA
HHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHCCCEECCCCCCCCCCEEEECCHHH
VERAGVLCKEAGAKRALPLPVSVPSHCALMKPAADELAKTLAELEFNAPQIPVINNVDVV
HHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHCCCCCCCCEECCCEEE
AETDPVKIKDALIRQLYSPVRWTECVEQMSAQGVEKLIEMGPGKVLTGLTKRIVKTLEGV
ECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
AVNDVASLDAVK
HHHHHHHHCCCC
>Mature Secondary Structure
MKERFMSKFAIVFPGQGSQAVGMLADLAEQYAVVKQTFAEASEVLGYDLWALVQDGPVED
CCCHHHHCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LNQTFRTQPALLAASVAIWRVWQQLGLEQPAVLAGHSLGEYSALVCAGVIDFKQAIKLVE
HHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
LRGQLMQQAVPAGTGAMYAIIGLEDEAIAKACADAAQGEVVSPVNFNSPGQVVIAGQKDA
HHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHCCCEECCCCCCCCCCEEEECCHHH
VERAGVLCKEAGAKRALPLPVSVPSHCALMKPAADELAKTLAELEFNAPQIPVINNVDVV
HHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHCCCCCCCCEECCCEEE
AETDPVKIKDALIRQLYSPVRWTECVEQMSAQGVEKLIEMGPGKVLTGLTKRIVKTLEGV
ECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
AVNDVASLDAVK
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]