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The map label for this gene is arsR [H]

Identifier: 147673929

GI number: 147673929

Start: 626582

End: 626923

Strand: Direct

Name: arsR [H]

Synonym: VC0395_A0586

Alternate gene names: 147673929

Gene position: 626582-626923 (Clockwise)

Preceding gene: 147673342

Following gene: 147674514

Centisome position: 20.72

GC content: 50.58

Gene sequence:

>342_bases
ATGTTACCCCACCAGTTTTTCAAATTACTCGCCGATGAAACGCGGGTGCGCTGCTTACTGATGATTGCTCGGGAAGAGAA
GGTTTGTGTGGCTGAACTTACCGAAGCTTTGAATGAGAGTCAGCCGAAAATTTCTCGCCATTTGGCATTGCTGCGTGCCA
GCGGCGTGGTGGTCGATATCCGTCAGGGGCAGTGGGTGTTTTATCGTATTTCCGATCAACTGCCGGGATGGATGCGCAAG
CAGATCCAAGGGTTGGTGGAATCCAACTGTCTTAAACAAGAATACCAGCAAGATATTCAGCGCCTCGCCGAGATGACTTC
TCGTCCTCAGTGCTGTGTGTAA

Upstream 100 bases:

>100_bases
TCATCGTTGATTTATTTTTATCCAATACATCAAACACTGATTGACATCGATTTTTTCCCCAATAAAATATCTGCATATCC
ATATATATTGGAGTTTGATT

Downstream 100 bases:

>100_bases
AGAACCAAGTTGAGTTATCCCTCAACGGCTTAGCGTTGTAGCCAAAATGGCTGCTTAGTTGGGAAGGGATAAAAACAAGT
TTAAAGGAAAAGGAAGATGG

Product: ArsR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 113; Mature: 113

Protein sequence:

>113_residues
MLPHQFFKLLADETRVRCLLMIAREEKVCVAELTEALNESQPKISRHLALLRASGVVVDIRQGQWVFYRISDQLPGWMRK
QIQGLVESNCLKQEYQQDIQRLAEMTSRPQCCV

Sequences:

>Translated_113_residues
MLPHQFFKLLADETRVRCLLMIAREEKVCVAELTEALNESQPKISRHLALLRASGVVVDIRQGQWVFYRISDQLPGWMRK
QIQGLVESNCLKQEYQQDIQRLAEMTSRPQCCV
>Mature_113_residues
MLPHQFFKLLADETRVRCLLMIAREEKVCVAELTEALNESQPKISRHLALLRASGVVVDIRQGQWVFYRISDQLPGWMRK
QIQGLVESNCLKQEYQQDIQRLAEMTSRPQCCV

Specific function: Transcriptional repressor for the arsEFG operon. ArsE is a trans-acting regulatory protein which controls its own expression. The repressive effect of ArsE is alleviated by oxyions of +III oxidation state of arsenic, antimony, and bismuth, as well as arse

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789916, Length=82, Percent_Identity=53.6585365853659, Blast_Score=96, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR018334
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 13160; Mature: 13160

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
8.0 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
8.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPHQFFKLLADETRVRCLLMIAREEKVCVAELTEALNESQPKISRHLALLRASGVVVDI
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEEEE
RQGQWVFYRISDQLPGWMRKQIQGLVESNCLKQEYQQDIQRLAEMTSRPQCCV
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLPHQFFKLLADETRVRCLLMIAREEKVCVAELTEALNESQPKISRHLALLRASGVVVDI
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEEEE
RQGQWVFYRISDQLPGWMRKQIQGLVESNCLKQEYQQDIQRLAEMTSRPQCCV
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7721697; 8041620; 9278503 [H]