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The map label for this gene is ompA [H]

Identifier: 147673624

GI number: 147673624

Start: 1918636

End: 1919601

Strand: Reverse

Name: ompA [H]

Synonym: VC0395_A1805

Alternate gene names: 147673624

Gene position: 1919601-1918636 (Counterclockwise)

Preceding gene: 147675108

Following gene: 147675048

Centisome position: 63.48

GC content: 47.72

Gene sequence:

>966_bases
ATGAAAAAGCTAGCGGCAATTATTTCAGCGACGTTACTTTTTGCTTCTTCTGCGGCAGTGGCAGAGGTGTATGTCGGAGG
TAAGGTCGGTAAATCTTGGTTGGATGACGCGTGTCTAGCTGGTCAATCTTGTGAAGATGATGATCAGGTTGTAGGCGCGT
TTCTGGGTTACCAAGCAAACAAATGGCTCTCTCTGGAAGCAGGCTACGACTACTTAGGTAAGTTTACTGCTGCTGGATTG
AATGATGAGAAGGTACAAGCGGTAACGCTAGCACCAAAACTCAGCATTCCTCTGACCGAAGGCATTGCGCTGTACGGTAA
AGTGGGTGGTGCTTATGTCGATTACGGCAGCAAGGACGACTACTCATACCTAGGTGCAGCAGGCCTAGAGTTCAACACTA
ACCACAATGTCACTATGCGTTTGGAATACCAAAACCTGACTGACATTAATAACGACATCGTACGTGCACGCGCAGAAACC
GCTACACTCGGTATCGCTTATAAGTTCGGTGGCAGTGAAGAGCCAGCACCAGTGGTAGAACAGCGTCCAGCTGAGCCTGC
ACCTGTTGCCGCACCAGTCGAGAAAGTGGCAGTCACTAAAACCTTTACTTTCCAACATCTGGATAGCAGCACCTTTGCTA
CTGCAAGTGCTGAGCTAAAACCAGCAACGGTTCAGAAGCTGGATAAAATTGTGGGTTACCTAAACCAATACCCACAAGCA
AAAGTAGAAGTAGTTGGTCACACAGACTCAACAGGTTCTGAAGCTTACAACCAAAAACTGTCTGAGCGTCGTGCTCAAGC
AGTAGCGAAAGCACTAGAAGCTCAAGGTATTGATGCATCTCGTATTTCAGCTAAAGGTCTAGGCGAAAGCAGCCCAATCG
CTTCTAACGCGACAGCAGAAGGTCGTGAGAAGAACCGTCGTGTTGAGCTAGTGATCCCTGAATTCCAGTACCAAGTTACT
GAATAA

Upstream 100 bases:

>100_bases
ACAAAAAGGTGATCTGGCTCGAGTACGAGTTAACCTTTTTGAACGGTCGAGGATCAGCGTATAACTCTCGACAATAATCA
TAAAGAAAAAAGGAAATACC

Downstream 100 bases:

>100_bases
TTTACGGTAATCATCAAGATTCAATCTACAAAGGCCCATTCGGGCCTTTGTTTTTTCTGGTGATAACAAAAATCGAGTGA
AAAAGGTTTTATTTCAGGTC

Product: outer membrane protein OmpA

Products: NA

Alternate protein names: Outer membrane protein II [H]

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MKKLAAIISATLLFASSAAVAEVYVGGKVGKSWLDDACLAGQSCEDDDQVVGAFLGYQANKWLSLEAGYDYLGKFTAAGL
NDEKVQAVTLAPKLSIPLTEGIALYGKVGGAYVDYGSKDDYSYLGAAGLEFNTNHNVTMRLEYQNLTDINNDIVRARAET
ATLGIAYKFGGSEEPAPVVEQRPAEPAPVAAPVEKVAVTKTFTFQHLDSSTFATASAELKPATVQKLDKIVGYLNQYPQA
KVEVVGHTDSTGSEAYNQKLSERRAQAVAKALEAQGIDASRISAKGLGESSPIASNATAEGREKNRRVELVIPEFQYQVT
E

Sequences:

>Translated_321_residues
MKKLAAIISATLLFASSAAVAEVYVGGKVGKSWLDDACLAGQSCEDDDQVVGAFLGYQANKWLSLEAGYDYLGKFTAAGL
NDEKVQAVTLAPKLSIPLTEGIALYGKVGGAYVDYGSKDDYSYLGAAGLEFNTNHNVTMRLEYQNLTDINNDIVRARAET
ATLGIAYKFGGSEEPAPVVEQRPAEPAPVAAPVEKVAVTKTFTFQHLDSSTFATASAELKPATVQKLDKIVGYLNQYPQA
KVEVVGHTDSTGSEAYNQKLSERRAQAVAKALEAQGIDASRISAKGLGESSPIASNATAEGREKNRRVELVIPEFQYQVT
E
>Mature_321_residues
MKKLAAIISATLLFASSAAVAEVYVGGKVGKSWLDDACLAGQSCEDDDQVVGAFLGYQANKWLSLEAGYDYLGKFTAAGL
NDEKVQAVTLAPKLSIPLTEGIALYGKVGGAYVDYGSKDDYSYLGAAGLEFNTNHNVTMRLEYQNLTDINNDIVRARAET
ATLGIAYKFGGSEEPAPVVEQRPAEPAPVAAPVEKVAVTKTFTFQHLDSSTFATASAELKPATVQKLDKIVGYLNQYPQA
KVEVVGHTDSTGSEAYNQKLSERRAQAVAKALEAQGIDASRISAKGLGESSPIASNATAEGREKNRRVELVIPEFQYQVT
E

Specific function: Required for the action of colicins K and L and for the stabilization of mating aggregates in conjugation. Serves as a receptor for a number of T-even like phages. Also acts as a porin with low permeability that allows slow penetration of small solutes [H

COG id: COG2885

COG function: function code M; Outer membrane protein and related peptidoglycan-associated (lipo)proteins

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 OmpA-like domain [H]

Homologues:

Organism=Escherichia coli, GI1787191, Length=343, Percent_Identity=32.6530612244898, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI48994946, Length=120, Percent_Identity=46.6666666666667, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1788957, Length=106, Percent_Identity=39.622641509434, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 3380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1480 Molecules/Cell In: Growth Phase, Mi

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011250
- InterPro:   IPR006664
- InterPro:   IPR002368
- InterPro:   IPR006690
- InterPro:   IPR000498
- InterPro:   IPR006665 [H]

Pfam domain/function: PF00691 OmpA; PF01389 OmpA_membrane [H]

EC number: NA

Molecular weight: Translated: 34286; Mature: 34286

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS01068 OMPA_1 ; PS51123 OMPA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLAAIISATLLFASSAAVAEVYVGGKVGKSWLDDACLAGQSCEDDDQVVGAFLGYQAN
CHHHHHHHHHHHHHHCCCHHEEEEECCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCCCC
KWLSLEAGYDYLGKFTAAGLNDEKVQAVTLAPKLSIPLTEGIALYGKVGGAYVDYGSKDD
CEEEEECCCHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCEEEEECCCCEEEECCCCCC
YSYLGAAGLEFNTNHNVTMRLEYQNLTDINNDIVRARAETATLGIAYKFGGSEEPAPVVE
CHHHCCCCEEECCCCCEEEEEEECCCCCCCHHHHHHHHCEEEEEEEEEECCCCCCCCHHH
QRPAEPAPVAAPVEKVAVTKTFTFQHLDSSTFATASAELKPATVQKLDKIVGYLNQYPQA
CCCCCCCCCCCCHHHHEEEEEEEEEECCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCC
KVEVVGHTDSTGSEAYNQKLSERRAQAVAKALEAQGIDASRISAKGLGESSPIASNATAE
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCC
GREKNRRVELVIPEFQYQVTE
CHHHCCEEEEEECCCEEEECC
>Mature Secondary Structure
MKKLAAIISATLLFASSAAVAEVYVGGKVGKSWLDDACLAGQSCEDDDQVVGAFLGYQAN
CHHHHHHHHHHHHHHCCCHHEEEEECCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCCCC
KWLSLEAGYDYLGKFTAAGLNDEKVQAVTLAPKLSIPLTEGIALYGKVGGAYVDYGSKDD
CEEEEECCCHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCEEEEECCCCEEEECCCCCC
YSYLGAAGLEFNTNHNVTMRLEYQNLTDINNDIVRARAETATLGIAYKFGGSEEPAPVVE
CHHHCCCCEEECCCCCEEEEEEECCCCCCCHHHHHHHHCEEEEEEEEEECCCCCCCCHHH
QRPAEPAPVAAPVEKVAVTKTFTFQHLDSSTFATASAELKPATVQKLDKIVGYLNQYPQA
CCCCCCCCCCCCHHHHEEEEEEEEEECCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCC
KVEVVGHTDSTGSEAYNQKLSERRAQAVAKALEAQGIDASRISAKGLGESSPIASNATAE
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCC
GREKNRRVELVIPEFQYQVTE
CHHHCCEEEEEECCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9524233; 1955870 [H]