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The map label for this gene is icd [H]

Identifier: 147673535

GI number: 147673535

Start: 734255

End: 736480

Strand: Direct

Name: icd [H]

Synonym: VC0395_A0711

Alternate gene names: 147673535

Gene position: 734255-736480 (Clockwise)

Preceding gene: 147673838

Following gene: 147674267

Centisome position: 24.28

GC content: 49.15

Gene sequence:

>2226_bases
ATGCCTACCAATAAACCTACAATTATTTATACCATTACTGATGAAGCCCCAGCGCTGGCAACGTATTCATTACTGCCGAT
TATTCAATCATTTACTGCTTCATCAGGCATTAACGTAGAAACACGCGATATTTCATTAGCTGGTCGTATTCTGGCTAATT
TCCCTGAGCATTTGACCGAAGAACAACGTATCAGCGATGCGTTGACTGAACTGGGTGAGCTAGCAAAAACGCCTGAAGCG
AACATCATTAAACTGCCAAATATTTCTGCTTCTGTTCCTCAACTCAAAGCGGCGATTAAAGAGCTGCAAGACAAAGGCTA
CGCACTGCCAAATTACCCAGAAGAACCGAGTAGCTACGAAGAAGAAGCGATCAAAGCAACTTATGACAAGATCAAGGGTA
GCGCGGTAAACCCAGTGTTACGTGAAGGTAACTCCGATCGCCGTGCTCCAGCCTCGGTGAAAAACTACGCCAAGAAAAAC
CCGCACTCCATGGGCGCTTGGAGTAAGGATTCAAAATCACATGTTGCAAGCATGAGCGATAAAGATTTCTTCGGTAGCGA
GAAGTCGATGACGGTGAGCGGCGCAACTAAAGTGGCGATTGAGTTCGTGGGTAAAGAGGGTGCAGTGAAAGTGCTGAAAA
AGCCTTTTGCGCTGCAAGATAAAGAGATCATCGATACCAGCGTGATGAGCAAAAAAGCGCTGATTGCCTTCTTTGAAAAA
GAAATCGCGGATGCGAAAGCGCAAGACGTGCTGTTCTCACTGCACATGAAAGCGACCATGATGAAAGTCTCGGATCCAGT
GATCTTCGGTCATGCGGTGAAGGTGTACTACAAAGCGGTTTTTGATAAGTATGGTCAACTGTTCGATCAGCTGGGTGTGG
ACGTTAATAACGGCTTAGGTGATGTCTACGCTAAAATTCAATCGCTGCCAGAAGCGCAACGTGCAGAAATTGAAGCGGCG
ATTCAAGCGGTATATGCGACGCAACCCGCTCTGGCGATGGTGGACTCTGACCGCGGTATCACCAACCTGCATGTACCAAG
CGATGTGATTGTTGATGCGTCTATGCCAGCAATGATCCGTACTTCAGGCCAAATGTGGGGCCCTGATGGTAAGCAGAAAG
ACACCAAAGCGACGATTCCCGATCGCTGCTACGCAGGCGTTTACCAAACCGTCATCGATTTCTGTAAACAGCACGGCGCG
TTTGACCCAACTACTATGGGCAGTGTGCCCAACGTGGGTCTGATGGCACAAAAAGCAGAAGAGTACGGCTCACACGATAA
GACCTTTATTCTGGATGCTGAAGGTGTGGTGCGTGTGATTGACGAAGCGGGCAAAGTGCTGCTGGAACAAAGCGTGGAAG
CGGGCGACATCTTCCGCATGTGTCAGGTAAAAGATGCGCCAATCCAAGATTGGGTAAAATTGGCGGTAACTCGTGCTCGC
GCTTCCAACACGCCAGCCGTTTTCTGGCTGGATCCTGCACGCGCTCATGACGCTGAGTTGATCAAGAAAGTGAATCAGTA
CCTACCTAATCACGATACCTCTGGTTTAGAAATCAAGATCCTGTCACCGATTGAAGCCACGCAATATTCACTTGTGCGTA
TGAAGGCGGGACAAGACACCATTTCTGTAACAGGTAACGTGCTACGTGATTACTTGACTGACTTATTCCCAATCCTTGAA
CTGGGTACTTCGGCGAAAATGCTCTCTATCGTTCCGTTGATGAACGGTGGTGGTTTGTTTGAAACGGGCGCGGGCGGCTC
GGCACCGAAGCACGTACAACAAGTACAAAAAGAGAACCACTTACGTTGGGATTCACTGGGTGAGTTTTTAGCGCTAGCCG
CATCTCTGGAGCACTTGAGTGTGGTCACTGGCAATCGCAAAGCACAAGTGTTGGCGGATGCGCTTGATAAAGCGACGGGT
AAGTTCCTCGATATGAACAAATCGCCTTCACGCCGTGTCGGTGAAATTGACAACCGTGGTAGCCATTTCTATTTGGCGAC
TTACTGGGCGCAAGCACTGGCTGAACAAACGGCAGATGCAGATCTCGCAGCTGAGTTTGCTCCGATTGCAAAAGCGCTTG
AAGAGAAAGAAGCGCAAATTGTCGCAGAACTGAATGGCGCGCAAGGCAAGCCTGGCGATTTGGGTGGCTATTACGCACCT
GAGTTTGCGAAGGTGGCTCCGCTTATGCGTCCTAGCTCGACCTTCAACGCGATCATTGACCGTTAA

Upstream 100 bases:

>100_bases
AGATCGTACTCAGGTTGAGGGGATGTCGCCGACTTGAGAACGGACAGTCACACAGTGTCATTGCATCCAATGGTGCTGTT
AGAACAGATAGGGAAAGTTC

Downstream 100 bases:

>100_bases
TCTAGTTTAGACACCAAAACAAAACCCGCCCAATTGGGCGGGTTTCTATTTTTGTGCTTTGCAAATTGCCAAAGCACGCT
AGTGTGGCAATCAATCCACT

Product: isocitrate dehydrogenase, NADP-dependent, monomeric type

Products: NA

Alternate protein names: IDH-II; IDP-2; NADP+-specific ICDH 2; Oxalosuccinate decarboxylase 2 [H]

Number of amino acids: Translated: 741; Mature: 740

Protein sequence:

>741_residues
MPTNKPTIIYTITDEAPALATYSLLPIIQSFTASSGINVETRDISLAGRILANFPEHLTEEQRISDALTELGELAKTPEA
NIIKLPNISASVPQLKAAIKELQDKGYALPNYPEEPSSYEEEAIKATYDKIKGSAVNPVLREGNSDRRAPASVKNYAKKN
PHSMGAWSKDSKSHVASMSDKDFFGSEKSMTVSGATKVAIEFVGKEGAVKVLKKPFALQDKEIIDTSVMSKKALIAFFEK
EIADAKAQDVLFSLHMKATMMKVSDPVIFGHAVKVYYKAVFDKYGQLFDQLGVDVNNGLGDVYAKIQSLPEAQRAEIEAA
IQAVYATQPALAMVDSDRGITNLHVPSDVIVDASMPAMIRTSGQMWGPDGKQKDTKATIPDRCYAGVYQTVIDFCKQHGA
FDPTTMGSVPNVGLMAQKAEEYGSHDKTFILDAEGVVRVIDEAGKVLLEQSVEAGDIFRMCQVKDAPIQDWVKLAVTRAR
ASNTPAVFWLDPARAHDAELIKKVNQYLPNHDTSGLEIKILSPIEATQYSLVRMKAGQDTISVTGNVLRDYLTDLFPILE
LGTSAKMLSIVPLMNGGGLFETGAGGSAPKHVQQVQKENHLRWDSLGEFLALAASLEHLSVVTGNRKAQVLADALDKATG
KFLDMNKSPSRRVGEIDNRGSHFYLATYWAQALAEQTADADLAAEFAPIAKALEEKEAQIVAELNGAQGKPGDLGGYYAP
EFAKVAPLMRPSSTFNAIIDR

Sequences:

>Translated_741_residues
MPTNKPTIIYTITDEAPALATYSLLPIIQSFTASSGINVETRDISLAGRILANFPEHLTEEQRISDALTELGELAKTPEA
NIIKLPNISASVPQLKAAIKELQDKGYALPNYPEEPSSYEEEAIKATYDKIKGSAVNPVLREGNSDRRAPASVKNYAKKN
PHSMGAWSKDSKSHVASMSDKDFFGSEKSMTVSGATKVAIEFVGKEGAVKVLKKPFALQDKEIIDTSVMSKKALIAFFEK
EIADAKAQDVLFSLHMKATMMKVSDPVIFGHAVKVYYKAVFDKYGQLFDQLGVDVNNGLGDVYAKIQSLPEAQRAEIEAA
IQAVYATQPALAMVDSDRGITNLHVPSDVIVDASMPAMIRTSGQMWGPDGKQKDTKATIPDRCYAGVYQTVIDFCKQHGA
FDPTTMGSVPNVGLMAQKAEEYGSHDKTFILDAEGVVRVIDEAGKVLLEQSVEAGDIFRMCQVKDAPIQDWVKLAVTRAR
ASNTPAVFWLDPARAHDAELIKKVNQYLPNHDTSGLEIKILSPIEATQYSLVRMKAGQDTISVTGNVLRDYLTDLFPILE
LGTSAKMLSIVPLMNGGGLFETGAGGSAPKHVQQVQKENHLRWDSLGEFLALAASLEHLSVVTGNRKAQVLADALDKATG
KFLDMNKSPSRRVGEIDNRGSHFYLATYWAQALAEQTADADLAAEFAPIAKALEEKEAQIVAELNGAQGKPGDLGGYYAP
EFAKVAPLMRPSSTFNAIIDR
>Mature_740_residues
PTNKPTIIYTITDEAPALATYSLLPIIQSFTASSGINVETRDISLAGRILANFPEHLTEEQRISDALTELGELAKTPEAN
IIKLPNISASVPQLKAAIKELQDKGYALPNYPEEPSSYEEEAIKATYDKIKGSAVNPVLREGNSDRRAPASVKNYAKKNP
HSMGAWSKDSKSHVASMSDKDFFGSEKSMTVSGATKVAIEFVGKEGAVKVLKKPFALQDKEIIDTSVMSKKALIAFFEKE
IADAKAQDVLFSLHMKATMMKVSDPVIFGHAVKVYYKAVFDKYGQLFDQLGVDVNNGLGDVYAKIQSLPEAQRAEIEAAI
QAVYATQPALAMVDSDRGITNLHVPSDVIVDASMPAMIRTSGQMWGPDGKQKDTKATIPDRCYAGVYQTVIDFCKQHGAF
DPTTMGSVPNVGLMAQKAEEYGSHDKTFILDAEGVVRVIDEAGKVLLEQSVEAGDIFRMCQVKDAPIQDWVKLAVTRARA
SNTPAVFWLDPARAHDAELIKKVNQYLPNHDTSGLEIKILSPIEATQYSLVRMKAGQDTISVTGNVLRDYLTDLFPILEL
GTSAKMLSIVPLMNGGGLFETGAGGSAPKHVQQVQKENHLRWDSLGEFLALAASLEHLSVVTGNRKAQVLADALDKATGK
FLDMNKSPSRRVGEIDNRGSHFYLATYWAQALAEQTADADLAAEFAPIAKALEEKEAQIVAELNGAQGKPGDLGGYYAPE
FAKVAPLMRPSSTFNAIIDR

Specific function: Unknown

COG id: COG2838

COG function: function code C; Monomeric isocitrate dehydrogenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monomeric-type IDH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001804
- InterPro:   IPR004436 [H]

Pfam domain/function: PF03971 IDH [H]

EC number: =1.1.1.42 [H]

Molecular weight: Translated: 80532; Mature: 80400

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTNKPTIIYTITDEAPALATYSLLPIIQSFTASSGINVETRDISLAGRILANFPEHLTE
CCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHCHHHHHH
EQRISDALTELGELAKTPEANIIKLPNISASVPQLKAAIKELQDKGYALPNYPEEPSSYE
HHHHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
EEAIKATYDKIKGSAVNPVLREGNSDRRAPASVKNYAKKNPHSMGAWSKDSKSHVASMSD
HHHHHHHHHHHCCCCCCHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHCCCC
KDFFGSEKSMTVSGATKVAIEFVGKEGAVKVLKKPFALQDKEIIDTSVMSKKALIAFFEK
CCCCCCCCCEEECCCCEEEEEECCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
EIADAKAQDVLFSLHMKATMMKVSDPVIFGHAVKVYYKAVFDKYGQLFDQLGVDVNNGLG
HHHCCHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
DVYAKIQSLPEAQRAEIEAAIQAVYATQPALAMVDSDRGITNLHVPSDVIVDASMPAMIR
HHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEECCCCEEECCCCCHHHH
TSGQMWGPDGKQKDTKATIPDRCYAGVYQTVIDFCKQHGAFDPTTMGSVPNVGLMAQKAE
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHH
EYGSHDKTFILDAEGVVRVIDEAGKVLLEQSVEAGDIFRMCQVKDAPIQDWVKLAVTRAR
HHCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHH
ASNTPAVFWLDPARAHDAELIKKVNQYLPNHDTSGLEIKILSPIEATQYSLVRMKAGQDT
CCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHEEEECCCCH
ISVTGNVLRDYLTDLFPILELGTSAKMLSIVPLMNGGGLFETGAGGSAPKHVQQVQKENH
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCEEECCCCCCCHHHHHHHHHHCC
LRWDSLGEFLALAASLEHLSVVTGNRKAQVLADALDKATGKFLDMNKSPSRRVGEIDNRG
CCHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCC
SHFYLATYWAQALAEQTADADLAAEFAPIAKALEEKEAQIVAELNGAQGKPGDLGGYYAP
CEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
EFAKVAPLMRPSSTFNAIIDR
HHHHHCCCCCCCCHHHHHCCC
>Mature Secondary Structure 
PTNKPTIIYTITDEAPALATYSLLPIIQSFTASSGINVETRDISLAGRILANFPEHLTE
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHCHHHHHH
EQRISDALTELGELAKTPEANIIKLPNISASVPQLKAAIKELQDKGYALPNYPEEPSSYE
HHHHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
EEAIKATYDKIKGSAVNPVLREGNSDRRAPASVKNYAKKNPHSMGAWSKDSKSHVASMSD
HHHHHHHHHHHCCCCCCHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHCCCC
KDFFGSEKSMTVSGATKVAIEFVGKEGAVKVLKKPFALQDKEIIDTSVMSKKALIAFFEK
CCCCCCCCCEEECCCCEEEEEECCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
EIADAKAQDVLFSLHMKATMMKVSDPVIFGHAVKVYYKAVFDKYGQLFDQLGVDVNNGLG
HHHCCHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
DVYAKIQSLPEAQRAEIEAAIQAVYATQPALAMVDSDRGITNLHVPSDVIVDASMPAMIR
HHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEECCCCEEECCCCCHHHH
TSGQMWGPDGKQKDTKATIPDRCYAGVYQTVIDFCKQHGAFDPTTMGSVPNVGLMAQKAE
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHH
EYGSHDKTFILDAEGVVRVIDEAGKVLLEQSVEAGDIFRMCQVKDAPIQDWVKLAVTRAR
HHCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHH
ASNTPAVFWLDPARAHDAELIKKVNQYLPNHDTSGLEIKILSPIEATQYSLVRMKAGQDT
CCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHEEEECCCCH
ISVTGNVLRDYLTDLFPILELGTSAKMLSIVPLMNGGGLFETGAGGSAPKHVQQVQKENH
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCEEECCCCCCCHHHHHHHHHHCC
LRWDSLGEFLALAASLEHLSVVTGNRKAQVLADALDKATGKFLDMNKSPSRRVGEIDNRG
CCHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCC
SHFYLATYWAQALAEQTADADLAAEFAPIAKALEEKEAQIVAELNGAQGKPGDLGGYYAP
CEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
EFAKVAPLMRPSSTFNAIIDR
HHHHHCCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8226630; 1295895 [H]