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The map label for this gene is erpA

Identifier: 147673412

GI number: 147673412

Start: 156633

End: 156974

Strand: Direct

Name: erpA

Synonym: VC0395_A0156

Alternate gene names: 147673412

Gene position: 156633-156974 (Clockwise)

Preceding gene: 147675430

Following gene: 147674168

Centisome position: 5.18

GC content: 45.32

Gene sequence:

>342_bases
GTGAGCGAAGTTAATGTTCCATTATCCTTTTCTGATGCGGCAGCAAAACGTGTTAAAGCGTTGATCGCAGAAGAAGAAAA
TCCATCGTTAATGTTGCGTGTTTACATCACTGGTGGTGGTTGTAGCGGCTTCCAATATGGCTTTACTTTCGATGAAACCG
TCAACGAAGGTGACACCAAAATTGAGAATAGCGGCGTCATTTTGGTGGTTGATCCTATGAGTCTGCAATATTTGATCGGC
GGAGTGGTCGATTATACCGAAGGTCTCGAAGGCTCAAGATTCTTCGTTAACAACCCCAATGCAACGACCACGTGTGGTTG
CGGCGCATCATTTAGCGTCTAA

Upstream 100 bases:

>100_bases
AACTCAGGTATTAGATAATCGCCGCCATTATCATTATTAGATCGGCAGCACATCGGATTTTGCGGTGTTGTTGTATTTTC
CACGACTGAGAGAGGTCATC

Downstream 100 bases:

>100_bases
TCCTGAGATTTTTCAGGAAAATAAGGCCAGTCGATAAACTCGATTGGCCGACGCTGCGTATTAGGATGTCACGCAGCGAT
AACAATAAGGAATAGTTATG

Product: iron-sulfur cluster insertion protein ErpA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 113; Mature: 112

Protein sequence:

>113_residues
MSEVNVPLSFSDAAAKRVKALIAEEENPSLMLRVYITGGGCSGFQYGFTFDETVNEGDTKIENSGVILVVDPMSLQYLIG
GVVDYTEGLEGSRFFVNNPNATTTCGCGASFSV

Sequences:

>Translated_113_residues
MSEVNVPLSFSDAAAKRVKALIAEEENPSLMLRVYITGGGCSGFQYGFTFDETVNEGDTKIENSGVILVVDPMSLQYLIG
GVVDYTEGLEGSRFFVNNPNATTTCGCGASFSV
>Mature_112_residues
SEVNVPLSFSDAAAKRVKALIAEEENPSLMLRVYITGGGCSGFQYGFTFDETVNEGDTKIENSGVILVVDPMSLQYLIGG
VVDYTEGLEGSRFFVNNPNATTTCGCGASFSV

Specific function: Required for insertion of 4Fe-4S clusters for at least ispG

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family

Homologues:

Organism=Homo sapiens, GI160420328, Length=86, Percent_Identity=46.5116279069767, Blast_Score=80, Evalue=5e-16,
Organism=Homo sapiens, GI52426768, Length=106, Percent_Identity=29.2452830188679, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1786351, Length=111, Percent_Identity=75.6756756756757, Blast_Score=181, Evalue=1e-47,
Organism=Escherichia coli, GI1788877, Length=110, Percent_Identity=40, Blast_Score=67, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71998452, Length=108, Percent_Identity=39.8148148148148, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI25146411, Length=113, Percent_Identity=28.3185840707965, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193209025, Length=109, Percent_Identity=29.3577981651376, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6323001, Length=106, Percent_Identity=36.7924528301887, Blast_Score=72, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24649697, Length=109, Percent_Identity=37.6146788990826, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24642263, Length=107, Percent_Identity=32.7102803738318, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ERPA_VIBC3 (A5F947)

Other databases:

- EMBL:   CP000627
- EMBL:   CP001235
- ProteinModelPortal:   A5F947
- SMR:   A5F947
- STRING:   A5F947
- GenomeReviews:   CP000627_GR
- GenomeReviews:   CP001235_GR
- KEGG:   vco:VC0395_A0156
- eggNOG:   COG0316
- HOGENOM:   HBG730174
- OMA:   TFDDQIN
- ProtClustDB:   PRK13623
- BioCyc:   VCHO345073:VC0395_A0156-MONOMER
- HAMAP:   MF_01380
- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR023063
- Gene3D:   G3DSA:2.60.300.12
- PANTHER:   PTHR10072
- TIGRFAMs:   TIGR00049

Pfam domain/function: PF01521 Fe-S_biosyn; SSF89360 HesB_yadR_yfhF-like

EC number: NA

Molecular weight: Translated: 12018; Mature: 11886

Theoretical pI: Translated: 3.94; Mature: 3.94

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEVNVPLSFSDAAAKRVKALIAEEENPSLMLRVYITGGGCSGFQYGFTFDETVNEGDTK
CCCCCCCEEECHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCEECCCCCCCCCE
IENSGVILVVDPMSLQYLIGGVVDYTEGLEGSRFFVNNPNATTTCGCGASFSV
ECCCCEEEEECCCCHHHHHCCHHHHCCCCCCCEEEEECCCCCEEECCCCCCCC
>Mature Secondary Structure 
SEVNVPLSFSDAAAKRVKALIAEEENPSLMLRVYITGGGCSGFQYGFTFDETVNEGDTK
CCCCCCEEECHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCEECCCCCCCCCE
IENSGVILVVDPMSLQYLIGGVVDYTEGLEGSRFFVNNPNATTTCGCGASFSV
ECCCCEEEEECCCCHHHHHCCHHHHCCCCCCCEEEEECCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA