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The map label for this gene is hlyB [H]

Identifier: 147673173

GI number: 147673173

Start: 1551050

End: 1553170

Strand: Reverse

Name: hlyB [H]

Synonym: VC0395_A1450

Alternate gene names: 147673173

Gene position: 1553170-1551050 (Counterclockwise)

Preceding gene: 147674940

Following gene: 147675262

Centisome position: 51.36

GC content: 47.76

Gene sequence:

>2121_bases
ATGCGCCAAATTTCTGTTCAGTGGAAAATCACACTACTTGCGGGGCTTTGTCTGGTTTTTACTTCTCTCGCTTTAATCGG
TTTTTCAATCTACAACGCGCGTGCGAGCCAGCAAACCGCCAAGCTGCAAAGTTCGGAGTCTGTCATTGATAAATCACAGC
AACTGCTGCAAACCGGTGCTTTATTGAACGCGACAGAGATTTCAGAGTACCTCAGTGAAGCGATATATCGTGCGGAAATG
TTGGCCGCGAATGCTCTGTTTTTGAAAAATAATTCAGAAGAAAACTTCGGTGAAAGTGAGGTGTTACGCACGTCGCTTGA
TGAAATGGTGCGTAAATCCGTACTTGGCTTTGACACCATAGAAGGCGCTTATCTGGTATTTCGTCCCAATATGCTCGACA
GTGAAGATTCCAATTATGTTAATGCAGATTATGTTGGCTCAAACGATATTGGTCAGTTTGCCGCCTACTGGACCAAGGCG
GCAAATGGGCAAAACGTGATTTCCCGCGTATTAACTCAAGCGCAACTCACAGAAGAATCGAATAAGGAGCGTTTTGTCTG
CCCGATTGAGCAAGCATCGCCCTGTATTACATCGCCGCGCATGGTGGAGTTTGAAACGGGACGCTATCTGGCCACGTCGC
TGTCTGTGCCGATTTTGATTGATGGTGTCGCCATCGGCTTTTATGGCATTGATCTGACGCTCGCGCCTTTGATTGGTATC
ACTCAAAAATCCGATAACAACCTGTTTGATGGACAAGGTAAAGTGTCGATTGTCAGTGAAAACAATGCGTTAGTGGCGAG
TGATGCTGCTTTTTTAACCCTTGGCGAAACTTTTCAAAGCGAGAACCTCAGCCGCTCAACGGTGAGTTCATTGTTGCAGG
CTGGGCAAGTCAACACTCAATGGAGTGAAGATGGACAATGGTTAGTGGTTTTTGCTCCTATCAAAGTGGCGAATCAAAAC
TGGGGTATCATTTTTGAAATGCCACGTCAAAGTGTCATGCAAGATGCCGAACAACTGGACATTTTACTTACAGAACAACT
TGAGCGCGGCATTCGTAGTGAATTGATGGTGGGTACGCTTATGGTCGTCGTGGGGCTATTGGTGGTCGCTCTTATGGCGA
TGCGTTTGGTGAGACCAATTCGAGCGGTTGCTGAACGATTACAAGATATTTCCTCTGGTGAAGGGGATTTAACTCAGCGT
TTGCAGGTGAATTCTGCCGATGAAATTGGCCAACTGGCACAGGGCTTTAACCTTTTTATGGATAAGTTACAGCCGATCAT
CCGCCGAGTTGTGGATAATACGGGACAAGTCGTGAGTACCACCGAGCAGGTCAAAAGTACGGTTGAATCAACGCGCCGTA
GCAGCGAAGCGCAATTTAAAGAAGTCGACAGTGTGGCAACCGCCGCAGAGGAGATGACTCAAACCTCAGCACATGTTGTC
GAGAATGCTCAGCGTGCGGTGAATGCGGCGAGCGATGCTCAGCGAGCTGCCCAAACAGGGGATGAAGTGATCCGCCATTC
ACAGATGCAGATGAACCAGTTGGTGGACAGAATGAATCTTGCCGTTCCTGTCGTGGAAGAGTTAGCACGCAACAACACTG
GGATTATTGAAATCTTAAGTGTGATTGAAGGCATTTCAGAGCAAACCAACTTGCTTGCATTAAATGCGGCGATTGAAGCG
GCTCGAGCTGGAGAGCAAGGCCGCGGTTTTGCTGTTGTTGCCGATGAAGTGCGCAGCCTTGCTAGTCGTACTCAAGCTTC
TGTTGGTGAAATTCGGTCCGTTATCAACAAAGTTGAATTGGGTACGCAAGATGTCGTGAAAGCGATTCAAGGCAGCAATG
AAACCGCACAAGCTACGGCAGAGCAAGTCGCGGATGCAGTTACTCAGCTCAACCGAGTGTTTTCGGCGATTCATGCCATC
AACGAGATGAGTCATCAAATCGTGCAAGCTGCGCAAGATCAGCAGACGGTATCGGCTCAAGTGACTCAAAGCGTGGTCAA
TATTCGCGATTTAAGTGCGCAAATTCTTTCAGAAACGGAAGCATCCGAAAAAGTGGGAGAGCAAATTGCGCGGTTGTCGT
TTGAACAACAAACTCTCGTCGGGCAGTTTAAAGTGAACTGA

Upstream 100 bases:

>100_bases
AGCAAAAGGTAACAAAGTTGTTGTTTAAAAGAATCAATAGACTTATTTTTAGCCTTATCACTCGATATACATGTCTAAAA
CGCAAACATAAGGATGTTGT

Downstream 100 bases:

>100_bases
GGCCAAGCGTTGTCAGACGAGAGTTACTCGTCTGACAGGGGGGCGATGGTTTTTGGTTGAATGCTGGGTGATACTGCAGC
GTCTGCCAGTTTTTGTTCAA

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 706; Mature: 706

Protein sequence:

>706_residues
MRQISVQWKITLLAGLCLVFTSLALIGFSIYNARASQQTAKLQSSESVIDKSQQLLQTGALLNATEISEYLSEAIYRAEM
LAANALFLKNNSEENFGESEVLRTSLDEMVRKSVLGFDTIEGAYLVFRPNMLDSEDSNYVNADYVGSNDIGQFAAYWTKA
ANGQNVISRVLTQAQLTEESNKERFVCPIEQASPCITSPRMVEFETGRYLATSLSVPILIDGVAIGFYGIDLTLAPLIGI
TQKSDNNLFDGQGKVSIVSENNALVASDAAFLTLGETFQSENLSRSTVSSLLQAGQVNTQWSEDGQWLVVFAPIKVANQN
WGIIFEMPRQSVMQDAEQLDILLTEQLERGIRSELMVGTLMVVVGLLVVALMAMRLVRPIRAVAERLQDISSGEGDLTQR
LQVNSADEIGQLAQGFNLFMDKLQPIIRRVVDNTGQVVSTTEQVKSTVESTRRSSEAQFKEVDSVATAAEEMTQTSAHVV
ENAQRAVNAASDAQRAAQTGDEVIRHSQMQMNQLVDRMNLAVPVVEELARNNTGIIEILSVIEGISEQTNLLALNAAIEA
ARAGEQGRGFAVVADEVRSLASRTQASVGEIRSVINKVELGTQDVVKAIQGSNETAQATAEQVADAVTQLNRVFSAIHAI
NEMSHQIVQAAQDQQTVSAQVTQSVVNIRDLSAQILSETEASEKVGEQIARLSFEQQTLVGQFKVN

Sequences:

>Translated_706_residues
MRQISVQWKITLLAGLCLVFTSLALIGFSIYNARASQQTAKLQSSESVIDKSQQLLQTGALLNATEISEYLSEAIYRAEM
LAANALFLKNNSEENFGESEVLRTSLDEMVRKSVLGFDTIEGAYLVFRPNMLDSEDSNYVNADYVGSNDIGQFAAYWTKA
ANGQNVISRVLTQAQLTEESNKERFVCPIEQASPCITSPRMVEFETGRYLATSLSVPILIDGVAIGFYGIDLTLAPLIGI
TQKSDNNLFDGQGKVSIVSENNALVASDAAFLTLGETFQSENLSRSTVSSLLQAGQVNTQWSEDGQWLVVFAPIKVANQN
WGIIFEMPRQSVMQDAEQLDILLTEQLERGIRSELMVGTLMVVVGLLVVALMAMRLVRPIRAVAERLQDISSGEGDLTQR
LQVNSADEIGQLAQGFNLFMDKLQPIIRRVVDNTGQVVSTTEQVKSTVESTRRSSEAQFKEVDSVATAAEEMTQTSAHVV
ENAQRAVNAASDAQRAAQTGDEVIRHSQMQMNQLVDRMNLAVPVVEELARNNTGIIEILSVIEGISEQTNLLALNAAIEA
ARAGEQGRGFAVVADEVRSLASRTQASVGEIRSVINKVELGTQDVVKAIQGSNETAQATAEQVADAVTQLNRVFSAIHAI
NEMSHQIVQAAQDQQTVSAQVTQSVVNIRDLSAQILSETEASEKVGEQIARLSFEQQTLVGQFKVN
>Mature_706_residues
MRQISVQWKITLLAGLCLVFTSLALIGFSIYNARASQQTAKLQSSESVIDKSQQLLQTGALLNATEISEYLSEAIYRAEM
LAANALFLKNNSEENFGESEVLRTSLDEMVRKSVLGFDTIEGAYLVFRPNMLDSEDSNYVNADYVGSNDIGQFAAYWTKA
ANGQNVISRVLTQAQLTEESNKERFVCPIEQASPCITSPRMVEFETGRYLATSLSVPILIDGVAIGFYGIDLTLAPLIGI
TQKSDNNLFDGQGKVSIVSENNALVASDAAFLTLGETFQSENLSRSTVSSLLQAGQVNTQWSEDGQWLVVFAPIKVANQN
WGIIFEMPRQSVMQDAEQLDILLTEQLERGIRSELMVGTLMVVVGLLVVALMAMRLVRPIRAVAERLQDISSGEGDLTQR
LQVNSADEIGQLAQGFNLFMDKLQPIIRRVVDNTGQVVSTTEQVKSTVESTRRSSEAQFKEVDSVATAAEEMTQTSAHVV
ENAQRAVNAASDAQRAAQTGDEVIRHSQMQMNQLVDRMNLAVPVVEELARNNTGIIEILSVIEGISEQTNLLALNAAIEA
ARAGEQGRGFAVVADEVRSLASRTQASVGEIRSVINKVELGTQDVVKAIQGSNETAQATAEQVADAVTQLNRVFSAIHAI
NEMSHQIVQAAQDQQTVSAQVTQSVVNIRDLSAQILSETEASEKVGEQIARLSFEQQTLVGQFKVN

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=302, Percent_Identity=31.4569536423841, Blast_Score=126, Evalue=4e-30,
Organism=Escherichia coli, GI1787690, Length=350, Percent_Identity=29.1428571428571, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1788195, Length=281, Percent_Identity=32.0284697508897, Blast_Score=117, Evalue=3e-27,
Organism=Escherichia coli, GI1788194, Length=350, Percent_Identity=30.2857142857143, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1789453, Length=335, Percent_Identity=30.7462686567164, Blast_Score=103, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 76937; Mature: 76937

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQISVQWKITLLAGLCLVFTSLALIGFSIYNARASQQTAKLQSSESVIDKSQQLLQTGA
CCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LLNATEISEYLSEAIYRAEMLAANALFLKNNSEENFGESEVLRTSLDEMVRKSVLGFDTI
CCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
EGAYLVFRPNMLDSEDSNYVNADYVGSNDIGQFAAYWTKAANGQNVISRVLTQAQLTEES
CCEEEEEECCCCCCCCCCEECCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
NKERFVCPIEQASPCITSPRMVEFETGRYLATSLSVPILIDGVAIGFYGIDLTLAPLIGI
CCCEEEEEHHHCCCCCCCCCEEEEECCCEEEECCCCCEEEECHHHHHEEHHHHHHHHHHC
TQKSDNNLFDGQGKVSIVSENNALVASDAAFLTLGETFQSENLSRSTVSSLLQAGQVNTQ
EECCCCCEECCCCCEEEEECCCEEEECCCHHEEECHHHHCCCCCHHHHHHHHHCCCCCCC
WSEDGQWLVVFAPIKVANQNWGIIFEMPRQSVMQDAEQLDILLTEQLERGIRSELMVGTL
CCCCCCEEEEEEEEEECCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MVVVGLLVVALMAMRLVRPIRAVAERLQDISSGEGDLTQRLQVNSADEIGQLAQGFNLFM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHHHHHH
DKLQPIIRRVVDNTGQVVSTTEQVKSTVESTRRSSEAQFKEVDSVATAAEEMTQTSAHVV
HHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ENAQRAVNAASDAQRAAQTGDEVIRHSQMQMNQLVDRMNLAVPVVEELARNNTGIIEILS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
VIEGISEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLASRTQASVGEIRSVINKVEL
HHHCCCCCCCEEEHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCC
GTQDVVKAIQGSNETAQATAEQVADAVTQLNRVFSAIHAINEMSHQIVQAAQDQQTVSAQ
CHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTQSVVNIRDLSAQILSETEASEKVGEQIARLSFEQQTLVGQFKVN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECC
>Mature Secondary Structure
MRQISVQWKITLLAGLCLVFTSLALIGFSIYNARASQQTAKLQSSESVIDKSQQLLQTGA
CCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LLNATEISEYLSEAIYRAEMLAANALFLKNNSEENFGESEVLRTSLDEMVRKSVLGFDTI
CCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
EGAYLVFRPNMLDSEDSNYVNADYVGSNDIGQFAAYWTKAANGQNVISRVLTQAQLTEES
CCEEEEEECCCCCCCCCCEECCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
NKERFVCPIEQASPCITSPRMVEFETGRYLATSLSVPILIDGVAIGFYGIDLTLAPLIGI
CCCEEEEEHHHCCCCCCCCCEEEEECCCEEEECCCCCEEEECHHHHHEEHHHHHHHHHHC
TQKSDNNLFDGQGKVSIVSENNALVASDAAFLTLGETFQSENLSRSTVSSLLQAGQVNTQ
EECCCCCEECCCCCEEEEECCCEEEECCCHHEEECHHHHCCCCCHHHHHHHHHCCCCCCC
WSEDGQWLVVFAPIKVANQNWGIIFEMPRQSVMQDAEQLDILLTEQLERGIRSELMVGTL
CCCCCCEEEEEEEEEECCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MVVVGLLVVALMAMRLVRPIRAVAERLQDISSGEGDLTQRLQVNSADEIGQLAQGFNLFM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHHHHHH
DKLQPIIRRVVDNTGQVVSTTEQVKSTVESTRRSSEAQFKEVDSVATAAEEMTQTSAHVV
HHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ENAQRAVNAASDAQRAAQTGDEVIRHSQMQMNQLVDRMNLAVPVVEELARNNTGIIEILS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
VIEGISEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLASRTQASVGEIRSVINKVEL
HHHCCCCCCCEEEHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCC
GTQDVVKAIQGSNETAQATAEQVADAVTQLNRVFSAIHAINEMSHQIVQAAQDQQTVSAQ
CHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTQSVVNIRDLSAQILSETEASEKVGEQIARLSFEQQTLVGQFKVN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]