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The map label for this gene is ppx [H]

Identifier: 147673098

GI number: 147673098

Start: 266031

End: 267533

Strand: Reverse

Name: ppx [H]

Synonym: VC0395_A0256

Alternate gene names: 147673098

Gene position: 267533-266031 (Counterclockwise)

Preceding gene: 147674904

Following gene: 147673880

Centisome position: 8.85

GC content: 47.5

Gene sequence:

>1503_bases
ATGACAACAGTAGTCAGTAACGCAAGAGAAATCGCTGCCATTGATCTGGGTTCGAACAGTTTTCATATGGTGGTCGCCAA
GGTGGTCGATCAAGATCTCCAATTGATTAGCCGCCATAAGCAGCGTGTTCGTCTTGCTGCGGGCTTGGATGAACAAAAAA
ATCTCGATGAAGAGTCGATCCAACGTGGCTTAGAGTGTTTGGCGATGTTCGCAGAACGATTGCAAGGCTTTGAGCCACGT
AATGTCCGTATTGCTGCAACCCACACTCTGCGCCAAGCCAGAAATGCCAATCTGTTTATTCAACGCGCTCTCGACGTGTT
GCCTTTTCCAATTGAAATCATTCCGGGCTCTGAAGAAGCCCGGTTGATTTATCTGGGGGTTGCCCATACCCAACCCCAAG
CGGATTCTATGCTGGTAGTGGATATTGGCGGCGGCAGCACGGAAATGATCATCGGCAAAGGCTTTGAAGCAGAACTGCTC
AACAGTAAGCAGATGGGCTGCGTCAACTTTACCGAGCGTTACTTTGCCAACGGCAAGCTATCACGTAAAAACTTTGCCCA
AGCGATTGTCGCCAGTGAGCAAAAATTAGAATCCATTGCCAGCAAATACCGTAAGAAAGGTTGGCAAATGGCGTTTGGTT
CTTCCGGTACCATCAAAGCGATTCATGAAGTGTTAATCGGGCAAGGTCATGAAGATGGACTCATCACCTTTGAGCGCCTG
AGCAAGTTAATTGAAAAACTCTGCGAATGGGACAGCATTGATGATTTACAACTGCCCGGCTTAACCGATGATCGAAAACC
CGTGTTTGCGGCGGGCGTTGCCATTCTTTCCGCGATCTTTCATGGTTTAAACATCAAAGAGATGCTTTTTTCGGATGGTG
CTTTGCGCGAAGGTCTGCTGTATGAGATGGAAGATCGCTTCAAGTATTCCGATATCCGTTTACGCACGACGGAAAATCTG
GCCGCCAAACATCTGGTCGATTTAGAGCATGCAGCCAAAGTCAAAGGTCACGCGCGTGAATTCTTGGCGCAAGTCGCCAA
TGAGTTGGGATTACCAGAAGGCAGTGAGCTGTGTGACCTACTCGAATGGGGCGCTCTGCTACATGAAGTGGGGCTGAGCA
TTAACTTACAAGGTTTTCATCGTCACTCCGCGTATATTTTGCGTCATAACAACATGGCAGGTTTCAACAGCGAACAACAA
CTCGTGCTCTCCAATTTGGCACGTTTCCAACGTAAATCGCTGAAATTGAATGAGCTGGATGACTTTAGTCTGTTTAAGAA
AAAACACATTATTGGCTTAATTCGAGTCCTACGACTGGCGATTGTGGTTAATAGGCAACGCAACGACGACCCTTTACCAC
CATTGACCCTATCCGCCAAAGATGATGAGTGGCGATTGGAGTGTGAACAGCCAGATTGGCTGGAAAACAATAAGTTGTTG
CATGCTGACTTACAAACAGAGCAAGAATACTGGCGTGAAGTCGGCTGGCAACTGCTGTTTTAA

Upstream 100 bases:

>100_bases
CGCGGTAATCGCAGAAAAGTACGCTCTCAGATTGCCATTTACGACTATCTTAAGAATGTCGAGAAGCAGACTCGTAAAGC
AAAAGGGCAACAAGAAACGA

Downstream 100 bases:

>100_bases
GCCAGCCTACTCACTGCAATTCGATGAAAAACGCCCAACTCAAGTTGGGCGTTTTTCATTTCATCACTCAGTCGATGATG
GGCTTAACGCCAACTTTGGC

Product: exopolyphosphatase

Products: NA

Alternate protein names: ExopolyPase; Metaphosphatase [H]

Number of amino acids: Translated: 500; Mature: 499

Protein sequence:

>500_residues
MTTVVSNAREIAAIDLGSNSFHMVVAKVVDQDLQLISRHKQRVRLAAGLDEQKNLDEESIQRGLECLAMFAERLQGFEPR
NVRIAATHTLRQARNANLFIQRALDVLPFPIEIIPGSEEARLIYLGVAHTQPQADSMLVVDIGGGSTEMIIGKGFEAELL
NSKQMGCVNFTERYFANGKLSRKNFAQAIVASEQKLESIASKYRKKGWQMAFGSSGTIKAIHEVLIGQGHEDGLITFERL
SKLIEKLCEWDSIDDLQLPGLTDDRKPVFAAGVAILSAIFHGLNIKEMLFSDGALREGLLYEMEDRFKYSDIRLRTTENL
AAKHLVDLEHAAKVKGHAREFLAQVANELGLPEGSELCDLLEWGALLHEVGLSINLQGFHRHSAYILRHNNMAGFNSEQQ
LVLSNLARFQRKSLKLNELDDFSLFKKKHIIGLIRVLRLAIVVNRQRNDDPLPPLTLSAKDDEWRLECEQPDWLENNKLL
HADLQTEQEYWREVGWQLLF

Sequences:

>Translated_500_residues
MTTVVSNAREIAAIDLGSNSFHMVVAKVVDQDLQLISRHKQRVRLAAGLDEQKNLDEESIQRGLECLAMFAERLQGFEPR
NVRIAATHTLRQARNANLFIQRALDVLPFPIEIIPGSEEARLIYLGVAHTQPQADSMLVVDIGGGSTEMIIGKGFEAELL
NSKQMGCVNFTERYFANGKLSRKNFAQAIVASEQKLESIASKYRKKGWQMAFGSSGTIKAIHEVLIGQGHEDGLITFERL
SKLIEKLCEWDSIDDLQLPGLTDDRKPVFAAGVAILSAIFHGLNIKEMLFSDGALREGLLYEMEDRFKYSDIRLRTTENL
AAKHLVDLEHAAKVKGHAREFLAQVANELGLPEGSELCDLLEWGALLHEVGLSINLQGFHRHSAYILRHNNMAGFNSEQQ
LVLSNLARFQRKSLKLNELDDFSLFKKKHIIGLIRVLRLAIVVNRQRNDDPLPPLTLSAKDDEWRLECEQPDWLENNKLL
HADLQTEQEYWREVGWQLLF
>Mature_499_residues
TTVVSNAREIAAIDLGSNSFHMVVAKVVDQDLQLISRHKQRVRLAAGLDEQKNLDEESIQRGLECLAMFAERLQGFEPRN
VRIAATHTLRQARNANLFIQRALDVLPFPIEIIPGSEEARLIYLGVAHTQPQADSMLVVDIGGGSTEMIIGKGFEAELLN
SKQMGCVNFTERYFANGKLSRKNFAQAIVASEQKLESIASKYRKKGWQMAFGSSGTIKAIHEVLIGQGHEDGLITFERLS
KLIEKLCEWDSIDDLQLPGLTDDRKPVFAAGVAILSAIFHGLNIKEMLFSDGALREGLLYEMEDRFKYSDIRLRTTENLA
AKHLVDLEHAAKVKGHAREFLAQVANELGLPEGSELCDLLEWGALLHEVGLSINLQGFHRHSAYILRHNNMAGFNSEQQL
VLSNLARFQRKSLKLNELDDFSLFKKKHIIGLIRVLRLAIVVNRQRNDDPLPPLTLSAKDDEWRLECEQPDWLENNKLLH
ADLQTEQEYWREVGWQLLF

Specific function: Degradation of inorganic polyphosphates. Orthophosphate is released progressively from the ends of polyphosphate [H]

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI1788848, Length=492, Percent_Identity=50.8130081300813, Blast_Score=494, Evalue=1e-141,
Organism=Escherichia coli, GI48994966, Length=493, Percent_Identity=41.1764705882353, Blast_Score=355, Evalue=3e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022371
- InterPro:   IPR003695 [H]

Pfam domain/function: PF02541 Ppx-GppA [H]

EC number: =3.6.1.11 [H]

Molecular weight: Translated: 56521; Mature: 56389

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTVVSNAREIAAIDLGSNSFHMVVAKVVDQDLQLISRHKQRVRLAAGLDEQKNLDEESI
CCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHH
QRGLECLAMFAERLQGFEPRNVRIAATHTLRQARNANLFIQRALDVLPFPIEIIPGSEEA
HHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHCCCCHHHHHHHHHCCCCEEEECCCCCC
RLIYLGVAHTQPQADSMLVVDIGGGSTEMIIGKGFEAELLNSKQMGCVNFTERYFANGKL
EEEEEEEECCCCCCCCEEEEEECCCCEEEEEECCCCHHHCCCCCCCCCCHHHHHHCCCCC
SRKNFAQAIVASEQKLESIASKYRKKGWQMAFGSSGTIKAIHEVLIGQGHEDGLITFERL
CHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCCCCCCCEEHHHH
SKLIEKLCEWDSIDDLQLPGLTDDRKPVFAAGVAILSAIFHGLNIKEMLFSDGALREGLL
HHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHCCCH
YEMEDRFKYSDIRLRTTENLAAKHLVDLEHAAKVKGHAREFLAQVANELGLPEGSELCDL
HHHHHCCEECCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LEWGALLHEVGLSINLQGFHRHSAYILRHNNMAGFNSEQQLVLSNLARFQRKSLKLNELD
HHHHHHHHHHCCEEEEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
DFSLFKKKHIIGLIRVLRLAIVVNRQRNDDPLPPLTLSAKDDEWRLECEQPDWLENNKLL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCEEEECCCCCCCCCCCEE
HADLQTEQEYWREVGWQLLF
EECCHHHHHHHHHHCCEECC
>Mature Secondary Structure 
TTVVSNAREIAAIDLGSNSFHMVVAKVVDQDLQLISRHKQRVRLAAGLDEQKNLDEESI
CCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHH
QRGLECLAMFAERLQGFEPRNVRIAATHTLRQARNANLFIQRALDVLPFPIEIIPGSEEA
HHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHCCCCHHHHHHHHHCCCCEEEECCCCCC
RLIYLGVAHTQPQADSMLVVDIGGGSTEMIIGKGFEAELLNSKQMGCVNFTERYFANGKL
EEEEEEEECCCCCCCCEEEEEECCCCEEEEEECCCCHHHCCCCCCCCCCHHHHHHCCCCC
SRKNFAQAIVASEQKLESIASKYRKKGWQMAFGSSGTIKAIHEVLIGQGHEDGLITFERL
CHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCCCCCCCEEHHHH
SKLIEKLCEWDSIDDLQLPGLTDDRKPVFAAGVAILSAIFHGLNIKEMLFSDGALREGLL
HHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHCCCH
YEMEDRFKYSDIRLRTTENLAAKHLVDLEHAAKVKGHAREFLAQVANELGLPEGSELCDL
HHHHHCCEECCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LEWGALLHEVGLSINLQGFHRHSAYILRHNNMAGFNSEQQLVLSNLARFQRKSLKLNELD
HHHHHHHHHHCCEEEEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
DFSLFKKKHIIGLIRVLRLAIVVNRQRNDDPLPPLTLSAKDDEWRLECEQPDWLENNKLL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCEEEECCCCCCCCCCCEE
HADLQTEQEYWREVGWQLLF
EECCHHHHHHHHHHCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]