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The map label for this gene is crtE [H]

Identifier: 146343288

GI number: 146343288

Start: 6757999

End: 6758949

Strand: Direct

Name: crtE [H]

Synonym: BRADO6509

Alternate gene names: 146343288

Gene position: 6757999-6758949 (Clockwise)

Preceding gene: 146343283

Following gene: 146343289

Centisome position: 90.63

GC content: 67.82

Gene sequence:

>951_bases
ATGCACAAACCCGTCGACCTCACCGATACGGCGGCCTTCGAGACCCAGCTCGATCGTTGGCGGGGACGCATCGGCGAAGC
GGTTGCCGAGGCCATGGCATTCGGCACGACGGTTCCGGCCCCGCTGCAGGCGGGCATGAGCCACGCAGTCCTGGCGGGCG
GCAAGAGATACCGCGGCATGCTCGTGCTCGCGCTCGGATCGGACCTCGGCGTGCCCGAGGAGCAGCTTTTGTCGTCGGCT
GTGGCTATTGAGACCATTCATGCAGCCTCCCTCGTGGTCGATGATCTTCCCTGCATGGACGACGCGCGGCGGCGACGGTC
GCAGCCGGCGACGCATGTCGCGTTCGGCGAGGCCACAGCAATCCTCAGCAGCATCGCCCTGATCGCCCGCGCGATGGAGG
TCGTGGCGAGGGACCGGCAACTTTCGCCCGCCTCCCGCAGTTCCATCGTGGACACTCTGTCGCACGCCATCGGCCCGCAG
GCCCTTTGTGGCGGGCAATATGACGATCTCTATCCTCCCTACTACGCGACCGAGCAGGATCTGATCCATCGCTATCAACG
CAAGACCAGCGCGCTGTTTGTCGCAGCGTTCCGCTGCCCCGCGCTCCTCGCGGAGGTGGATCCGGAGACGCTGCTGCGCA
TCGCCCGCGCGGGCCAGCGGCTCGGCGTCGCATTTCAGATATTCGACGATCTCCTCGACCTGACAGGCGATGCCCATGCA
ATCGGCAAGGATGTCGGCCAGGACCATGGCACCGTGACGCTCGCCACGCTGCTCGGACCCGCGCGGGCGGCCGAACGGGC
GGCGGATGAGCTTGCGGCCGTGCAGAAGGAACTGCGCGAGACGGTCGGCCCCGGGCGCGCCCTCGACCTGATCAGGCGGA
TGGCCGCACGCATCGCCGGCACCGGCAAGAAATCCGCCGGACGCGACGATCTGCGGCCGCATGCCGGCTGA

Upstream 100 bases:

>100_bases
ATCTCGTCCGTTCACGTTAAGACACCATGCTTGCACTGTTCACCTCAGAACGGAACGGCCTGGACGTGTCACCGGATCAC
CTCGAAGGCAGGTTCAGAGT

Downstream 100 bases:

>100_bases
AGCCCGGGACAGCCCATCGCACCGGTCGCAGATCAGATTGTCGCCTCCTGTTTCGGCGGCCCGCATCTGCGAGGAACATC
CTGCTACCGACATTCCGAGC

Product: geranylgeranyl pyrophosphate synthetase

Products: NA

Alternate protein names: GGPP synthase; Farnesyltranstransferase [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MHKPVDLTDTAAFETQLDRWRGRIGEAVAEAMAFGTTVPAPLQAGMSHAVLAGGKRYRGMLVLALGSDLGVPEEQLLSSA
VAIETIHAASLVVDDLPCMDDARRRRSQPATHVAFGEATAILSSIALIARAMEVVARDRQLSPASRSSIVDTLSHAIGPQ
ALCGGQYDDLYPPYYATEQDLIHRYQRKTSALFVAAFRCPALLAEVDPETLLRIARAGQRLGVAFQIFDDLLDLTGDAHA
IGKDVGQDHGTVTLATLLGPARAAERAADELAAVQKELRETVGPGRALDLIRRMAARIAGTGKKSAGRDDLRPHAG

Sequences:

>Translated_316_residues
MHKPVDLTDTAAFETQLDRWRGRIGEAVAEAMAFGTTVPAPLQAGMSHAVLAGGKRYRGMLVLALGSDLGVPEEQLLSSA
VAIETIHAASLVVDDLPCMDDARRRRSQPATHVAFGEATAILSSIALIARAMEVVARDRQLSPASRSSIVDTLSHAIGPQ
ALCGGQYDDLYPPYYATEQDLIHRYQRKTSALFVAAFRCPALLAEVDPETLLRIARAGQRLGVAFQIFDDLLDLTGDAHA
IGKDVGQDHGTVTLATLLGPARAAERAADELAAVQKELRETVGPGRALDLIRRMAARIAGTGKKSAGRDDLRPHAG
>Mature_316_residues
MHKPVDLTDTAAFETQLDRWRGRIGEAVAEAMAFGTTVPAPLQAGMSHAVLAGGKRYRGMLVLALGSDLGVPEEQLLSSA
VAIETIHAASLVVDDLPCMDDARRRRSQPATHVAFGEATAILSSIALIARAMEVVARDRQLSPASRSSIVDTLSHAIGPQ
ALCGGQYDDLYPPYYATEQDLIHRYQRKTSALFVAAFRCPALLAEVDPETLLRIARAGQRLGVAFQIFDDLLDLTGDAHA
IGKDVGQDHGTVTLATLLGPARAAERAADELAAVQKELRETVGPGRALDLIRRMAARIAGTGKKSAGRDDLRPHAG

Specific function: Unknown

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786623, Length=278, Percent_Identity=37.0503597122302, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1789578, Length=204, Percent_Identity=30.3921568627451, Blast_Score=87, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17505681, Length=190, Percent_Identity=31.5789473684211, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6325188, Length=221, Percent_Identity=24.8868778280543, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.29 [H]

Molecular weight: Translated: 33714; Mature: 33714

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKPVDLTDTAAFETQLDRWRGRIGEAVAEAMAFGTTVPAPLQAGMSHAVLAGGKRYRGM
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHCCCHHCCE
LVLALGSDLGVPEEQLLSSAVAIETIHAASLVVDDLPCMDDARRRRSQPATHVAFGEATA
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHH
ILSSIALIARAMEVVARDRQLSPASRSSIVDTLSHAIGPQALCGGQYDDLYPPYYATEQD
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCHHH
LIHRYQRKTSALFVAAFRCPALLAEVDPETLLRIARAGQRLGVAFQIFDDLLDLTGDAHA
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHH
IGKDVGQDHGTVTLATLLGPARAAERAADELAAVQKELRETVGPGRALDLIRRMAARIAG
HHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
TGKKSAGRDDLRPHAG
CCCCCCCCCCCCCCCC
>Mature Secondary Structure
MHKPVDLTDTAAFETQLDRWRGRIGEAVAEAMAFGTTVPAPLQAGMSHAVLAGGKRYRGM
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHCCCHHCCE
LVLALGSDLGVPEEQLLSSAVAIETIHAASLVVDDLPCMDDARRRRSQPATHVAFGEATA
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHH
ILSSIALIARAMEVVARDRQLSPASRSSIVDTLSHAIGPQALCGGQYDDLYPPYYATEQD
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCHHH
LIHRYQRKTSALFVAAFRCPALLAEVDPETLLRIARAGQRLGVAFQIFDDLLDLTGDAHA
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHH
IGKDVGQDHGTVTLATLLGPARAAERAADELAAVQKELRETVGPGRALDLIRRMAARIAG
HHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
TGKKSAGRDDLRPHAG
CCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2254247 [H]