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The map label for this gene is crp [C]

Identifier: 146343093

GI number: 146343093

Start: 6528866

End: 6529525

Strand: Reverse

Name: crp [C]

Synonym: BRADO6288

Alternate gene names: 146343093

Gene position: 6529525-6528866 (Counterclockwise)

Preceding gene: 146343094

Following gene: 146343091

Centisome position: 87.57

GC content: 58.48

Gene sequence:

>660_bases
ATGCGCGACGAGAGTGCGAGATACGAATTCAATCCCAACGCTCTCCTGGGACAGCCGAGCAACGGTATCGTACTCGAGCG
ATACCAGAAGGGGAGCCGGATCTTTGTTCAGGGTGACTCTGCTGACTCGATCGGCTTCCTACGAGCGGGAACGGCAAAGG
CTACGACACTATCTGCGGTCGGCAAGGAAGCGATTGTCGCGATCCTGAGGCCGGGCCAGTTCTTTGGCGAGGCTTGCCTG
CGGGGATCAACCCTGCGAACCTCAACGGTGGTCGCGTTAGAGGACTGCCAAGTCACGTTGATCACCAGGCAAAGAATGCT
GGCGCTGCTACATGACGAGCCGAGCTTCTTGGACTTCTTCCTCGCATATCTGCTGTCGCGCAACGATCGGCTGGAAGGAG
ATCTGATCAATCAGCTACTCCACTCGGCCGAGCAGCGGCTGGCGCGCGTGTTACTATTGCTCGCCGGGTTCGCCCAAGAA
GATGATCAACCGATTACTGTTTCTCTCAGTCAAGAGTCTCTCGCGGAGATGGTCGGCACGACCCGGTCGCGGGTTTCGAC
CTTCATGAACAGGTTTCGCGAAAAGGGGTTCATCAGCTACGACAGCCGCGGGCGCCTCCAGGTCTATACGGCGCTGCTGC
TATCGGTGCTCGCAGGCTAG

Upstream 100 bases:

>100_bases
GACCACAATGATCGGTATCATAATCATTCTAAAGAATGAAGCCTGATGGTGTGGGACGGGGGCTGCTGGACCAAGCGGCG
ATTGCGCCTCCGATAGTATC

Downstream 100 bases:

>100_bases
AGCAGCCGGTAGCAATGGATCATCGATGGGACGGCGCCTCATGGCGTCAGCTATTCGAGAGTGCTGACATAGGCAGCGAC
CTGCTTGATCTGGACCTCGG

Product: CRP/FNR family transcriptional regulator

Products: NA

Alternate protein names: Crp/FNR Family Transcriptional Regulator; Crp/Fnr Family Transcriptional Regulator; CRP/FNR Family Transcriptional Regulator; Transcriptional Regulator; Crp Family Transcriptional Regulator; Catabolite Gene Activator; Transcriptional Regulatory Protein; Cyclic-AMP Receptor-Like Protein; Transcriptional Regulator CAP Family; CRP Family Transcriptional Regulator; Fumarate And Nitrate Reduction Regulatory Protein; Global Nitrogen Regulator; Regulatory Protein; Response Regulator Receiver; Transcriptional Regulator Crp; Transcription Regulator; CAMP-Bindin Transcriptional Regulator; CAMP Receptor Protein; CAMP-Regulatory Protein; CRP Family Global Nitrogen Regulatory Protein; Transcriptional Regulator Crp/Fnr Family Protein

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MRDESARYEFNPNALLGQPSNGIVLERYQKGSRIFVQGDSADSIGFLRAGTAKATTLSAVGKEAIVAILRPGQFFGEACL
RGSTLRTSTVVALEDCQVTLITRQRMLALLHDEPSFLDFFLAYLLSRNDRLEGDLINQLLHSAEQRLARVLLLLAGFAQE
DDQPITVSLSQESLAEMVGTTRSRVSTFMNRFREKGFISYDSRGRLQVYTALLLSVLAG

Sequences:

>Translated_219_residues
MRDESARYEFNPNALLGQPSNGIVLERYQKGSRIFVQGDSADSIGFLRAGTAKATTLSAVGKEAIVAILRPGQFFGEACL
RGSTLRTSTVVALEDCQVTLITRQRMLALLHDEPSFLDFFLAYLLSRNDRLEGDLINQLLHSAEQRLARVLLLLAGFAQE
DDQPITVSLSQESLAEMVGTTRSRVSTFMNRFREKGFISYDSRGRLQVYTALLLSVLAG
>Mature_219_residues
MRDESARYEFNPNALLGQPSNGIVLERYQKGSRIFVQGDSADSIGFLRAGTAKATTLSAVGKEAIVAILRPGQFFGEACL
RGSTLRTSTVVALEDCQVTLITRQRMLALLHDEPSFLDFFLAYLLSRNDRLEGDLINQLLHSAEQRLARVLLLLAGFAQE
DDQPITVSLSQESLAEMVGTTRSRVSTFMNRFREKGFISYDSRGRLQVYTALLLSVLAG

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 24239; Mature: 24239

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDESARYEFNPNALLGQPSNGIVLERYQKGSRIFVQGDSADSIGFLRAGTAKATTLSAV
CCCCCCCEEECCCCEECCCCCCEEEEEECCCCEEEEECCCCCCCEEEECCCCHHHHHHHH
GKEAIVAILRPGQFFGEACLRGSTLRTSTVVALEDCQVTLITRQRMLALLHDEPSFLDFF
HHHHHHEEECCCHHHHHHHHCCCCCCCEEEEEECCCEEEEHHHHHHHHHHCCCCHHHHHH
LAYLLSRNDRLEGDLINQLLHSAEQRLARVLLLLAGFAQEDDQPITVSLSQESLAEMVGT
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECHHHHHHHHCC
TRSRVSTFMNRFREKGFISYDSRGRLQVYTALLLSVLAG
HHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MRDESARYEFNPNALLGQPSNGIVLERYQKGSRIFVQGDSADSIGFLRAGTAKATTLSAV
CCCCCCCEEECCCCEECCCCCCEEEEEECCCCEEEEECCCCCCCEEEECCCCHHHHHHHH
GKEAIVAILRPGQFFGEACLRGSTLRTSTVVALEDCQVTLITRQRMLALLHDEPSFLDFF
HHHHHHEEECCCHHHHHHHHCCCCCCCEEEEEECCCEEEEHHHHHHHHHHCCCCHHHHHH
LAYLLSRNDRLEGDLINQLLHSAEQRLARVLLLLAGFAQEDDQPITVSLSQESLAEMVGT
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECHHHHHHHHCC
TRSRVSTFMNRFREKGFISYDSRGRLQVYTALLLSVLAG
HHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA