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The map label for this gene is mgtC [H]

Identifier: 146343086

GI number: 146343086

Start: 6522849

End: 6523565

Strand: Reverse

Name: mgtC [H]

Synonym: BRADO6281

Alternate gene names: 146343086

Gene position: 6523565-6522849 (Counterclockwise)

Preceding gene: 146343088

Following gene: 146343083

Centisome position: 87.49

GC content: 67.92

Gene sequence:

>717_bases
ATGCGATTCCTGCATACCTTCCAGCTTTTTGATTTCCTCGACACCCTGGTCAGCCTGTTCGCGGCCTTCGTGCTGGGCAC
CTTGATCGGCGCCGAGCGGCAATTCCGGCAGCGCAGCGCCGGCCTGCGCACCAACGTCCTGGTGGCGGTGGGCGCCGCCG
CCTTCGTCGATATCGGTAATCGCCTCACGGGCGCGGACGGTGCCGTGCGCATCATCGCCTACGTCGTCTCGGGCATCGGC
TTTCTCGGCGCCGGCACGATCATGAAGGAGGGCATGAACGTCCGGGGCCTCAACACCGCGGCGACCTTGTGGGCCTCCGC
GGCCGTCGGCGCCTGTGCAGGCGCGGATCTCGTCGCCCAATCGGTGGCGCTGACGCTGTTCGTGCTCGCCGGCAACACGC
TGCTGCGGCCGCTGGTCAACGCGATCGACCGCATCCCGCTCAACGCGGCGACCTCCGAGGCCAACTACGAGATCGTGGTC
ACCACCGACGTTCTGCATGCCGCGCAATTGCGCGAGGCGCTGGATGAACGGCTGGAGGCCGCCAAATACCCGGTGCGCGA
GACCGAGGTGGCCTACCGATCCGATGACATCGCGGAGATCACCGCAACCCTGGTGCCGCTCGCGGCCGAGACCGCCGATC
TGGACCGGGTCACCGCGGAACTGGCGAAGCTGCCCGGCGTGCGGCACGCGACCTGGAACATCAGCGCGCTCGAGTGA

Upstream 100 bases:

>100_bases
AAGAAGACGGCGTTCTCGCGGCAATCCGGCCGTCGGAGGACATTTGTGTGTCTGCTGCCGGGCAGACGGTCCGGCATAGG
ACCGGAGACAGCTCCTGCTC

Downstream 100 bases:

>100_bases
TGTACCGCGTGATCTGCTACTTGATGCAGCGGCCGACATCGCCGGCGGCGGTCGGCGATTCATAGCCTCCGGGGGACGTC
GGCTGGCCGTTGAAGAACAC

Product: putative MgtC-magnesium transport family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MRFLHTFQLFDFLDTLVSLFAAFVLGTLIGAERQFRQRSAGLRTNVLVAVGAAAFVDIGNRLTGADGAVRIIAYVVSGIG
FLGAGTIMKEGMNVRGLNTAATLWASAAVGACAGADLVAQSVALTLFVLAGNTLLRPLVNAIDRIPLNAATSEANYEIVV
TTDVLHAAQLREALDERLEAAKYPVRETEVAYRSDDIAEITATLVPLAAETADLDRVTAELAKLPGVRHATWNISALE

Sequences:

>Translated_238_residues
MRFLHTFQLFDFLDTLVSLFAAFVLGTLIGAERQFRQRSAGLRTNVLVAVGAAAFVDIGNRLTGADGAVRIIAYVVSGIG
FLGAGTIMKEGMNVRGLNTAATLWASAAVGACAGADLVAQSVALTLFVLAGNTLLRPLVNAIDRIPLNAATSEANYEIVV
TTDVLHAAQLREALDERLEAAKYPVRETEVAYRSDDIAEITATLVPLAAETADLDRVTAELAKLPGVRHATWNISALE
>Mature_238_residues
MRFLHTFQLFDFLDTLVSLFAAFVLGTLIGAERQFRQRSAGLRTNVLVAVGAAAFVDIGNRLTGADGAVRIIAYVVSGIG
FLGAGTIMKEGMNVRGLNTAATLWASAAVGACAGADLVAQSVALTLFVLAGNTLLRPLVNAIDRIPLNAATSEANYEIVV
TTDVLHAAQLREALDERLEAAKYPVRETEVAYRSDDIAEITATLVPLAAETADLDRVTAELAKLPGVRHATWNISALE

Specific function: Virulence factor required for growth in low Mg(2+) medium and for intramacrophage survival. May be involved in regulating membrane potential by activating Na(+)/K(+)-ATPase [H]

COG id: COG1285

COG function: function code S; Uncharacterized membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MgtC/SapB family [H]

Homologues:

Organism=Escherichia coli, GI1789924, Length=113, Percent_Identity=39.8230088495575, Blast_Score=75, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003416 [H]

Pfam domain/function: PF02308 MgtC [H]

EC number: NA

Molecular weight: Translated: 25238; Mature: 25238

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFLHTFQLFDFLDTLVSLFAAFVLGTLIGAERQFRQRSAGLRTNVLVAVGAAAFVDIGN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
RLTGADGAVRIIAYVVSGIGFLGAGTIMKEGMNVRGLNTAATLWASAAVGACAGADLVAQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHH
SVALTLFVLAGNTLLRPLVNAIDRIPLNAATSEANYEIVVTTDVLHAAQLREALDERLEA
HHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHH
AKYPVRETEVAYRSDDIAEITATLVPLAAETADLDRVTAELAKLPGVRHATWNISALE
HHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECC
>Mature Secondary Structure
MRFLHTFQLFDFLDTLVSLFAAFVLGTLIGAERQFRQRSAGLRTNVLVAVGAAAFVDIGN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
RLTGADGAVRIIAYVVSGIGFLGAGTIMKEGMNVRGLNTAATLWASAAVGACAGADLVAQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHH
SVALTLFVLAGNTLLRPLVNAIDRIPLNAATSEANYEIVVTTDVLHAAQLREALDERLEA
HHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHH
AKYPVRETEVAYRSDDIAEITATLVPLAAETADLDRVTAELAKLPGVRHATWNISALE
HHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA