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The map label for this gene is dcp [H]

Identifier: 146343066

GI number: 146343066

Start: 6503379

End: 6505460

Strand: Reverse

Name: dcp [H]

Synonym: BRADO6258

Alternate gene names: 146343066

Gene position: 6505460-6503379 (Counterclockwise)

Preceding gene: 146343073

Following gene: 146343065

Centisome position: 87.24

GC content: 67.05

Gene sequence:

>2082_bases
ATGTCCGACACGACCGCCTCGATCGACGCCGCAAGCAATCCGCTGCTCGTGGCCTGGGACACCCCGCACCAGACACCGCC
CTTCGACGCGATCAGGCCCGAGCACTTCCTGCCGGCCTTCGAGCGCGCCTTCGCCGACCACACCGCTGAAATCACCGCGA
TCACCCACGATCCGGCGGAGCCCGACTTCGCCAACACCATCACGGCGCTGGAGCGCTCGGGCAAGCTGCTGTCGAAGGTC
GCCGCCGTCTTCTATGATCTTGTCTCGGCGCACTCCAACCCGGCGATTCTGGAGATCGACAAGGAAGTGTCGCTGCGGAT
GGCGCGGCACTGGAACCCGATCATGATGAACGCCGTGCTGTTTGGTCGCATCGCGCTGCTCTACGACAACCGCAAGACGC
TGACGCTCACCGGCGAGGAGCAGCGGCTGCTGGAGCGCACCTACACCCGCTTCCGCCGCGCCGGCGCAGGCCTCAAGGAC
GAGGCCAAGGCGCGCATGGCCGAGATCAACGAGCAGCTCGCCCAGCTCGGCACCACCTTCAGCCACCACGTGCTCGGCGA
CGAGCAGGACTGGTTCCTGGAGCTCGGCGAGGATGACCGCGCCGGCCTCTCCGACAGCTTCGTCGCCGCCGCCAAGGCTG
CGGCGGAGGAGCGCGGCATGCCCGGCAAGGCGATCGTGACCCTGTCGCGCTCCTCGGTCGAGCCGTTCCTGCAGAGCTCC
TCCCGCCGCGACCTGCGCGAGAAGGTGTTCAAGGCCTTCACCGCGCGCGGCGACAACGGGAATACCAACGACAACAACGC
GGTCATCGGCCAGATCCTGGCGCTGCGCGAGGAGTCCGCCAAGATCATGGGCTTCCCGAACTTCGCGGTCTATCGCCTCG
AGGATTCCATGGCGAAGACCCCGGAGGCGGTGCGCGGCCTGTTGGAGCGGGTCTGGAAGCCAGCGCGCGCCAAGGCGCTG
GCCGATCGCGACCAGCTGCAACAGCTGATCACGGAAGAGGGCGGCAACTTCAAGCTCGAGGCCTGGGACTGGCGCTATTA
CGCCGAGAAGCTGCGCCAGGCGAAGGCGAACTTCGACGACGCCGCGATCAAGCCGTATCTCGCGCTCGACAACATGGTCG
CGGCGGCCTTCGACTGCGCGACGCGGCTGTTCGGGATCACCTTCGCCGAGCGCAAGGACATCCCGGTCTGGCACCCGGAC
GTCCGGGTGTGGGAGATCAAGGAAGCCGACGGCCGCCACAAGGCGCTGTTCTATGGCGACTACTTCGCCCGGCCGTCGAA
GCGCTCCGGCGCCTGGATGACCTCGCTGCGCGACCAGCAGAAGCTCGACGGCGACACCGCGCCGCTGATCATCAACGTCT
GCAATTTCGCCAAGGGCGCCGACGGCCAGCCCTCGCTGCTGTCGCCGGACGATGCCCGCACGCTGTTCCACGAGTTCGGC
CACGGCCTGCATGGCATCCTCTCCAACGTGACCTATCCGTCGCTGTCGGGCACGTCTGTCTTCACCGACTTCGTCGAGCT
GCCGTCGCAGCTCTACGAGCACTGGCAGGAGCGCCCCGAGGTGCTGCAGACCTTCGCGAAGCACTACCAGACCGGCGAGC
CGCTGCCGCAGGACCTGCTGGAGCGCTTCCTCGCCGCGCGCCGTTTCAACCAGGGTTTTGCCACCGTCGAGTTCGTCTCG
TCGGCGCTGATCGATCTGGAGTTCCACACCCAGCCGGCCGCGGCATCGAAGGATGTGCGCGCGTTCGAGACGGCCGAGAT
GGAGAAGATCGGCATGCCCAAGGAGATCGCGCTGCGCCACCGGCCGACCCAATTCGGCCATATCTTCTCGGGAGACCACT
ACGCGGCGGGCTATTACAGCTACATGTGGTCGGAGGTGATGGATGCGGATGCCTTCGGGGCCTTCGAGGAAGCCGGCAAC
ATCTTCGATCCCGCCGTCGCCAAGCGGCTTCACGACAACGTCTACTCCTCTGGAGGCTCGCTCGATCCCGAGGCGGCTTA
CGTCGCGTTCCGCGGCCGCGAGCCCGAGCCCGACGCGCTGCTCCGCCGGCGCGGCCTGCTCGACATTCCCGCAGCGGCTT
GA

Upstream 100 bases:

>100_bases
AATCTCTCCGAAATGGTCCCGGCCTTCAAGGGGAAATGACCCAAAAAGGACCGGCTCCGTGGTAAGAGGGGCGCCTGTTT
GATCCGGAGAGCAAGAGCCG

Downstream 100 bases:

>100_bases
GGTGAGGGCGATGATCCGTGCCGTTATGGCGGCGCTGCTGCTCATGCTGGGGGCGGGCGCGGCGAGCGCTCATCCCCATG
TCTGGGTCACCGCGACCAGC

Product: peptidyl-dipeptidase

Products: NA

Alternate protein names: Dipeptidyl carboxypeptidase [H]

Number of amino acids: Translated: 693; Mature: 692

Protein sequence:

>693_residues
MSDTTASIDAASNPLLVAWDTPHQTPPFDAIRPEHFLPAFERAFADHTAEITAITHDPAEPDFANTITALERSGKLLSKV
AAVFYDLVSAHSNPAILEIDKEVSLRMARHWNPIMMNAVLFGRIALLYDNRKTLTLTGEEQRLLERTYTRFRRAGAGLKD
EAKARMAEINEQLAQLGTTFSHHVLGDEQDWFLELGEDDRAGLSDSFVAAAKAAAEERGMPGKAIVTLSRSSVEPFLQSS
SRRDLREKVFKAFTARGDNGNTNDNNAVIGQILALREESAKIMGFPNFAVYRLEDSMAKTPEAVRGLLERVWKPARAKAL
ADRDQLQQLITEEGGNFKLEAWDWRYYAEKLRQAKANFDDAAIKPYLALDNMVAAAFDCATRLFGITFAERKDIPVWHPD
VRVWEIKEADGRHKALFYGDYFARPSKRSGAWMTSLRDQQKLDGDTAPLIINVCNFAKGADGQPSLLSPDDARTLFHEFG
HGLHGILSNVTYPSLSGTSVFTDFVELPSQLYEHWQERPEVLQTFAKHYQTGEPLPQDLLERFLAARRFNQGFATVEFVS
SALIDLEFHTQPAAASKDVRAFETAEMEKIGMPKEIALRHRPTQFGHIFSGDHYAAGYYSYMWSEVMDADAFGAFEEAGN
IFDPAVAKRLHDNVYSSGGSLDPEAAYVAFRGREPEPDALLRRRGLLDIPAAA

Sequences:

>Translated_693_residues
MSDTTASIDAASNPLLVAWDTPHQTPPFDAIRPEHFLPAFERAFADHTAEITAITHDPAEPDFANTITALERSGKLLSKV
AAVFYDLVSAHSNPAILEIDKEVSLRMARHWNPIMMNAVLFGRIALLYDNRKTLTLTGEEQRLLERTYTRFRRAGAGLKD
EAKARMAEINEQLAQLGTTFSHHVLGDEQDWFLELGEDDRAGLSDSFVAAAKAAAEERGMPGKAIVTLSRSSVEPFLQSS
SRRDLREKVFKAFTARGDNGNTNDNNAVIGQILALREESAKIMGFPNFAVYRLEDSMAKTPEAVRGLLERVWKPARAKAL
ADRDQLQQLITEEGGNFKLEAWDWRYYAEKLRQAKANFDDAAIKPYLALDNMVAAAFDCATRLFGITFAERKDIPVWHPD
VRVWEIKEADGRHKALFYGDYFARPSKRSGAWMTSLRDQQKLDGDTAPLIINVCNFAKGADGQPSLLSPDDARTLFHEFG
HGLHGILSNVTYPSLSGTSVFTDFVELPSQLYEHWQERPEVLQTFAKHYQTGEPLPQDLLERFLAARRFNQGFATVEFVS
SALIDLEFHTQPAAASKDVRAFETAEMEKIGMPKEIALRHRPTQFGHIFSGDHYAAGYYSYMWSEVMDADAFGAFEEAGN
IFDPAVAKRLHDNVYSSGGSLDPEAAYVAFRGREPEPDALLRRRGLLDIPAAA
>Mature_692_residues
SDTTASIDAASNPLLVAWDTPHQTPPFDAIRPEHFLPAFERAFADHTAEITAITHDPAEPDFANTITALERSGKLLSKVA
AVFYDLVSAHSNPAILEIDKEVSLRMARHWNPIMMNAVLFGRIALLYDNRKTLTLTGEEQRLLERTYTRFRRAGAGLKDE
AKARMAEINEQLAQLGTTFSHHVLGDEQDWFLELGEDDRAGLSDSFVAAAKAAAEERGMPGKAIVTLSRSSVEPFLQSSS
RRDLREKVFKAFTARGDNGNTNDNNAVIGQILALREESAKIMGFPNFAVYRLEDSMAKTPEAVRGLLERVWKPARAKALA
DRDQLQQLITEEGGNFKLEAWDWRYYAEKLRQAKANFDDAAIKPYLALDNMVAAAFDCATRLFGITFAERKDIPVWHPDV
RVWEIKEADGRHKALFYGDYFARPSKRSGAWMTSLRDQQKLDGDTAPLIINVCNFAKGADGQPSLLSPDDARTLFHEFGH
GLHGILSNVTYPSLSGTSVFTDFVELPSQLYEHWQERPEVLQTFAKHYQTGEPLPQDLLERFLAARRFNQGFATVEFVSS
ALIDLEFHTQPAAASKDVRAFETAEMEKIGMPKEIALRHRPTQFGHIFSGDHYAAGYYSYMWSEVMDADAFGAFEEAGNI
FDPAVAKRLHDNVYSSGGSLDPEAAYVAFRGREPEPDALLRRRGLLDIPAAA

Specific function: Removes dipeptides from the C-termini of N-blocked tripeptides, tetrapeptides and larger peptides [H]

COG id: COG0339

COG function: function code E; Zn-dependent oligopeptidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M3 family [H]

Homologues:

Organism=Homo sapiens, GI4507491, Length=607, Percent_Identity=29.6540362438221, Blast_Score=241, Evalue=2e-63,
Organism=Homo sapiens, GI14149738, Length=597, Percent_Identity=27.9731993299832, Blast_Score=231, Evalue=2e-60,
Organism=Homo sapiens, GI156105687, Length=643, Percent_Identity=24.7278382581649, Blast_Score=159, Evalue=6e-39,
Organism=Escherichia coli, GI1787819, Length=679, Percent_Identity=39.3225331369661, Blast_Score=478, Evalue=1e-136,
Organism=Escherichia coli, GI1789913, Length=686, Percent_Identity=34.9854227405248, Blast_Score=379, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI32565901, Length=559, Percent_Identity=22.5402504472272, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71999758, Length=480, Percent_Identity=21.6666666666667, Blast_Score=71, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319793, Length=618, Percent_Identity=27.0226537216829, Blast_Score=191, Evalue=3e-49,
Organism=Saccharomyces cerevisiae, GI6322715, Length=634, Percent_Identity=22.2397476340694, Blast_Score=131, Evalue=4e-31,
Organism=Drosophila melanogaster, GI21356111, Length=492, Percent_Identity=27.4390243902439, Blast_Score=183, Evalue=3e-46,
Organism=Drosophila melanogaster, GI20129717, Length=555, Percent_Identity=24.8648648648649, Blast_Score=151, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001567 [H]

Pfam domain/function: PF01432 Peptidase_M3 [H]

EC number: =3.4.15.5 [H]

Molecular weight: Translated: 77470; Mature: 77339

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDTTASIDAASNPLLVAWDTPHQTPPFDAIRPEHFLPAFERAFADHTAEITAITHDPAE
CCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCC
PDFANTITALERSGKLLSKVAAVFYDLVSAHSNPAILEIDKEVSLRMARHWNPIMMNAVL
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHCCCHHHHHHHH
FGRIALLYDNRKTLTLTGEEQRLLERTYTRFRRAGAGLKDEAKARMAEINEQLAQLGTTF
HHHEEEEECCCEEEEEECHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCH
SHHVLGDEQDWFLELGEDDRAGLSDSFVAAAKAAAEERGMPGKAIVTLSRSSVEPFLQSS
HHHCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHCC
SRRDLREKVFKAFTARGDNGNTNDNNAVIGQILALREESAKIMGFPNFAVYRLEDSMAKT
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCEECCCCEEEEEECHHHHCC
PEAVRGLLERVWKPARAKALADRDQLQQLITEEGGNFKLEAWDWRYYAEKLRQAKANFDD
HHHHHHHHHHHCCHHHHHHHHCHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHCCCCC
AAIKPYLALDNMVAAAFDCATRLFGITFAERKDIPVWHPDVRVWEIKEADGRHKALFYGD
HHCCHHHHHHHHHHHHHHHHHHHHHCEECCCCCCCCCCCCCEEEEEECCCCCEEEEEEEH
YFARPSKRSGAWMTSLRDQQKLDGDTAPLIINVCNFAKGADGQPSLLSPDDARTLFHEFG
HHCCCCCCCCCHHHHHHHHHHCCCCCCCHHEEEHHCCCCCCCCCCCCCCHHHHHHHHHHC
HGLHGILSNVTYPSLSGTSVFTDFVELPSQLYEHWQERPEVLQTFAKHYQTGEPLPQDLL
CHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
ERFLAARRFNQGFATVEFVSSALIDLEFHTQPAAASKDVRAFETAEMEKIGMPKEIALRH
HHHHHHHHHCCCCHHHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHC
RPTQFGHIFSGDHYAAGYYSYMWSEVMDADAFGAFEEAGNIFDPAVAKRLHDNVYSSGGS
CCCCCCCEECCCCCCHHHHHHHHHHHHCHHHCCCHHHCCCCCCHHHHHHHHHHHHCCCCC
LDPEAAYVAFRGREPEPDALLRRRGLLDIPAAA
CCCCCEEEEEECCCCCHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SDTTASIDAASNPLLVAWDTPHQTPPFDAIRPEHFLPAFERAFADHTAEITAITHDPAE
CCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCC
PDFANTITALERSGKLLSKVAAVFYDLVSAHSNPAILEIDKEVSLRMARHWNPIMMNAVL
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHCCCHHHHHHHH
FGRIALLYDNRKTLTLTGEEQRLLERTYTRFRRAGAGLKDEAKARMAEINEQLAQLGTTF
HHHEEEEECCCEEEEEECHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCH
SHHVLGDEQDWFLELGEDDRAGLSDSFVAAAKAAAEERGMPGKAIVTLSRSSVEPFLQSS
HHHCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHCC
SRRDLREKVFKAFTARGDNGNTNDNNAVIGQILALREESAKIMGFPNFAVYRLEDSMAKT
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCEECCCCEEEEEECHHHHCC
PEAVRGLLERVWKPARAKALADRDQLQQLITEEGGNFKLEAWDWRYYAEKLRQAKANFDD
HHHHHHHHHHHCCHHHHHHHHCHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHCCCCC
AAIKPYLALDNMVAAAFDCATRLFGITFAERKDIPVWHPDVRVWEIKEADGRHKALFYGD
HHCCHHHHHHHHHHHHHHHHHHHHHCEECCCCCCCCCCCCCEEEEEECCCCCEEEEEEEH
YFARPSKRSGAWMTSLRDQQKLDGDTAPLIINVCNFAKGADGQPSLLSPDDARTLFHEFG
HHCCCCCCCCCHHHHHHHHHHCCCCCCCHHEEEHHCCCCCCCCCCCCCCHHHHHHHHHHC
HGLHGILSNVTYPSLSGTSVFTDFVELPSQLYEHWQERPEVLQTFAKHYQTGEPLPQDLL
CHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
ERFLAARRFNQGFATVEFVSSALIDLEFHTQPAAASKDVRAFETAEMEKIGMPKEIALRH
HHHHHHHHHCCCCHHHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHC
RPTQFGHIFSGDHYAAGYYSYMWSEVMDADAFGAFEEAGNIFDPAVAKRLHDNVYSSGGS
CCCCCCCEECCCCCCHHHHHHHHHHHHCHHHCCCHHHCCCCCCHHHHHHHHHHHHCCCCC
LDPEAAYVAFRGREPEPDALLRRRGLLDIPAAA
CCCCCEEEEEECCCCCHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1537804; 11677609 [H]