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The map label for this gene is nahR [H]

Identifier: 146343063

GI number: 146343063

Start: 6500218

End: 6501159

Strand: Direct

Name: nahR [H]

Synonym: BRADO6255

Alternate gene names: 146343063

Gene position: 6500218-6501159 (Clockwise)

Preceding gene: 146343060

Following gene: 146343067

Centisome position: 87.17

GC content: 71.23

Gene sequence:

>942_bases
TTGAAGAATGATCAGATGCCGAGCCTTGCCCATGTCGACCTCAACCTTCTGGTGCTGTTCGAGGCGCTCCTGTCCGAGCG
CAACGTGACCCGCGCGGCCGTGCGGGTCGGCCTGGCGCAACCGTCCGCCAGCAAGGCGCTCGACCGACTGCGGCACCTGT
TCGGCGACCCGCTGTTCCTGCGGGCGCCCGGCGGCATGCGCCCGACGCCGCGGGCGCTGGAATTGGCGCCGGAGATCGCC
TTGGTGCTCGAGCGGGTGCGGGCGCTGGTCGCGGCCGAACTTCCGTTCGATCCGGCGACGGCGCGCGGCAGCCTGCGGCT
GGCGATGTCGGATGCGGCCGAGTTCGTGCTGCTGCCGGGTTTGGTGGCGCAACTGGCCGGCACCGCGCCAGGTGTGACCC
TGCAGGCGCGGCCGCTCGACAAGGACCGGGTGTTCGCCGAGCTCGACGAGGGACGGCTTGACGCCGTGGTCGGCGTCTTC
CGCGAACTGCCCAAGCGCTTTCGCTCAGCACCGCTGTTCGAGGAACGCTTCGTCTGCCTGGCGCGCGCCGACCATCCGCG
CCTGGCGACGGGTCTGACGCTCGAGACCTATGTGGAGCTGCCGCATCTGCTGGTCACGCTGCGCGACGACCGCAAGGGCG
CTGTCGACGACGCGCTCGAAGCGATAGGACTGCACCGCCGCGTGGCCGCGACGCTGACGCGCTTTCTGGCGCTGCCCCCC
GTGCTCGCATTCAGCGACGCGATCGCCACGGTGCCGTCGCGCTTTGCCGCGGCGAGCGCGCCGAACTGCCGCCTGCATGA
GCCGCCACTGGCCTTGCCGCGCTGGACCGAGCAACTCGTCTGGCGCGCCGGCGCCGAACGCGAGCCGATGATCGCGTGGG
GGCTGCAACTGATCCGCAGCGCAGGCGAAACGCAACGCCTGCCCCCGGCGTTCCGCGCTTGA

Upstream 100 bases:

>100_bases
TGGGGGAGGACATGGGACGGGCTCCATGGCTGGGACTGCCGCTGTTTTGCCCGACGTCCTGTCATTCCGAAAATGACATC
TGGCAATTCTGATCATTCCC

Downstream 100 bases:

>100_bases
GGCGGCCTCTGCTCCGCGGCGCGGTTGCCGGGTTCGCTGCCGGCAACGCCCCTCGATCACCCGCGCGATGGGTCCCCGCG
TTCGCGGCGCCGACATCTTC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MKNDQMPSLAHVDLNLLVLFEALLSERNVTRAAVRVGLAQPSASKALDRLRHLFGDPLFLRAPGGMRPTPRALELAPEIA
LVLERVRALVAAELPFDPATARGSLRLAMSDAAEFVLLPGLVAQLAGTAPGVTLQARPLDKDRVFAELDEGRLDAVVGVF
RELPKRFRSAPLFEERFVCLARADHPRLATGLTLETYVELPHLLVTLRDDRKGAVDDALEAIGLHRRVAATLTRFLALPP
VLAFSDAIATVPSRFAAASAPNCRLHEPPLALPRWTEQLVWRAGAEREPMIAWGLQLIRSAGETQRLPPAFRA

Sequences:

>Translated_313_residues
MKNDQMPSLAHVDLNLLVLFEALLSERNVTRAAVRVGLAQPSASKALDRLRHLFGDPLFLRAPGGMRPTPRALELAPEIA
LVLERVRALVAAELPFDPATARGSLRLAMSDAAEFVLLPGLVAQLAGTAPGVTLQARPLDKDRVFAELDEGRLDAVVGVF
RELPKRFRSAPLFEERFVCLARADHPRLATGLTLETYVELPHLLVTLRDDRKGAVDDALEAIGLHRRVAATLTRFLALPP
VLAFSDAIATVPSRFAAASAPNCRLHEPPLALPRWTEQLVWRAGAEREPMIAWGLQLIRSAGETQRLPPAFRA
>Mature_313_residues
MKNDQMPSLAHVDLNLLVLFEALLSERNVTRAAVRVGLAQPSASKALDRLRHLFGDPLFLRAPGGMRPTPRALELAPEIA
LVLERVRALVAAELPFDPATARGSLRLAMSDAAEFVLLPGLVAQLAGTAPGVTLQARPLDKDRVFAELDEGRLDAVVGVF
RELPKRFRSAPLFEERFVCLARADHPRLATGLTLETYVELPHLLVTLRDDRKGAVDDALEAIGLHRRVAATLTRFLALPP
VLAFSDAIATVPSRFAAASAPNCRLHEPPLALPRWTEQLVWRAGAEREPMIAWGLQLIRSAGETQRLPPAFRA

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=293, Percent_Identity=27.3037542662116, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1790147, Length=305, Percent_Identity=27.2131147540984, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI87081766, Length=297, Percent_Identity=23.2323232323232, Blast_Score=86, Evalue=4e-18,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34238; Mature: 34238

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNDQMPSLAHVDLNLLVLFEALLSERNVTRAAVRVGLAQPSASKALDRLRHLFGDPLFL
CCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEE
RAPGGMRPTPRALELAPEIALVLERVRALVAAELPFDPATARGSLRLAMSDAAEFVLLPG
ECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHH
LVAQLAGTAPGVTLQARPLDKDRVFAELDEGRLDAVVGVFRELPKRFRSAPLFEERFVCL
HHHHHHCCCCCCEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
ARADHPRLATGLTLETYVELPHLLVTLRDDRKGAVDDALEAIGLHRRVAATLTRFLALPP
HCCCCCCHHHCCHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
VLAFSDAIATVPSRFAAASAPNCRLHEPPLALPRWTEQLVWRAGAEREPMIAWGLQLIRS
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHH
AGETQRLPPAFRA
CCCCCCCCCCCCC
>Mature Secondary Structure
MKNDQMPSLAHVDLNLLVLFEALLSERNVTRAAVRVGLAQPSASKALDRLRHLFGDPLFL
CCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEE
RAPGGMRPTPRALELAPEIALVLERVRALVAAELPFDPATARGSLRLAMSDAAEFVLLPG
ECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHH
LVAQLAGTAPGVTLQARPLDKDRVFAELDEGRLDAVVGVFRELPKRFRSAPLFEERFVCL
HHHHHHCCCCCCEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
ARADHPRLATGLTLETYVELPHLLVTLRDDRKGAVDDALEAIGLHRRVAATLTRFLALPP
HCCCCCCHHHCCHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
VLAFSDAIATVPSRFAAASAPNCRLHEPPLALPRWTEQLVWRAGAEREPMIAWGLQLIRS
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHH
AGETQRLPPAFRA
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]