Click here to switch to the map view.

The map label for this gene is zraS [C]

Identifier: 146342592

GI number: 146342592

Start: 5955175

End: 5956647

Strand: Direct

Name: zraS [C]

Synonym: BRADO5755

Alternate gene names: 146342592

Gene position: 5955175-5956647 (Clockwise)

Preceding gene: 146342590

Following gene: 146342593

Centisome position: 79.86

GC content: 68.09

Gene sequence:

>1473_bases
ATGTTCCTGTGGCGACGTTGGCGCGACGTGTTGTTTCGCGGCGTGATCGCCGGGCTCGCCGGCTATGCGGCGGTCTGCGG
CGTCGGGCGCCTCGTTGCCATCGTCGATCTCTGGCTTCCGACTGCCGGCGCCGGCACGGTGATCGACGCCGTGCAGGCCC
TGCTCTCGTTCGGCCTCATCGCACTCATGCTGAAGATTTTGCCGCAACTCCTGGTGCTGCCGACGCGCATCACGCTGCAG
AAGGCCTATGCCCAGCTCGAGGAGGAGGTCCGGCAGCGCCGCGCCGCGGAAGCCATGGTGCGGCGCTTCCAGGAGATCGA
GGCCAATGAGGCCCAGGTCCGACAGGCGCAGAAGATGGAGGCGATCGGCCAGCTCACCGGCGGCGTCGCGCACGACTTCA
ACAACATCCTCACCGTCATCACCGGGACGATCGAGATTCTCGCCGACGCGGTCAAGGACAAGCCGCAGCTCGCCGGCATC
GCTGCGATGATCAGCGCCGCGGCCGAGCGCGGCGCGGACCTGACCCGGCATCTCCTCGCCTTCTCGCGCCGGCAGCCGCT
GCAGCCGCGCGCCACCGACATCAACGCGCTCGTGGTCGACGCCGCGCGCCTGCTGCGGCCGACGCTCGGCGAGCAAATCG
AGATCGAATCGATGCTCTCCCATGACAGCGCGCCGGCGCTGATCGATCCGAGCCAGCTCTCGACCGCGATCCTCAACCTC
GCGATCAACGCGCGCGATGCCATGCCCGATGGCGGCAAGCTGACGCTGGAGACCAAGAATATCACGCTCGACGAGGACTA
CGCGCGGCTGAACCGCGATGCCAAGCCCGGCGGCTACGTGATGATCGCGGTCAGCGACACCGGCCAGGGCATTCCCGCCT
CGCTGCTCGACAAGGTGTTCGAGCCGTTCTTCACCACCAAGGACGTCGGCAAGGGCTCCGGCCTCGGACTCAGCATGGTC
TATGGCTTCGTCAAGCAGTCCAACGGCCACGTCAAGATCTACAGCGAGCAAGGTCACGGCACCACGGTGAAGCTGTATCT
GCCGCGGGCGGCGAGCGCGCCGGAGCTGCCGGCCGCCGAGAGCGGCCGTCCGGCGGTGGCGCGCGGCGACGAGACGATCC
TGATCGTCGAGGATGACGCGCTGGTGCGCGACTACGTCGTCGCCCAGGTGCGCCGGCTCGGCTACCGGACGCTGTCGGCG
AGCAACGCCGCCGAGGGGCTCGCGATCATCGACAGTCCCGAGCGGATCGACCTGCTGTTCACCGACGTCATCATCCCCGG
CGGCAAGAACGGCCGCCAGCTCGCGATCGAGGCCGAGAAGCGGCGCCCCGGGCTGAAGGTGCTGTACACCTCGGGCTACA
CGGAGAACGCGATCGTGCATCACGGCCGCCTCGATGCCGACGTCCTGCTGCTCGCCAAGCCCTATCTCAGCGCCGATCTC
GCACGCATGATCCGGACCGCGCTAGAGGCGTGA

Upstream 100 bases:

>100_bases
GACGCCGCTGGCGGCAGGCGTGCCAGGATGGATTTGGCTGCAGGCCGCGTCCCATGCCGTCATCGCCTGCGCCTTTTTCA
CGATCGCCGCGGTGATCGGC

Downstream 100 bases:

>100_bases
GGCGGCCGGCAGGGTTTGCCACAATGCCCGCCCCAAATTCCGGTGTCGTCCCGGCCTTGAGCCGGGACCCATAGCCACCG
GCTTCGGTGGCTAGGCCAGA

Product: sensor histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MFLWRRWRDVLFRGVIAGLAGYAAVCGVGRLVAIVDLWLPTAGAGTVIDAVQALLSFGLIALMLKILPQLLVLPTRITLQ
KAYAQLEEEVRQRRAAEAMVRRFQEIEANEAQVRQAQKMEAIGQLTGGVAHDFNNILTVITGTIEILADAVKDKPQLAGI
AAMISAAAERGADLTRHLLAFSRRQPLQPRATDINALVVDAARLLRPTLGEQIEIESMLSHDSAPALIDPSQLSTAILNL
AINARDAMPDGGKLTLETKNITLDEDYARLNRDAKPGGYVMIAVSDTGQGIPASLLDKVFEPFFTTKDVGKGSGLGLSMV
YGFVKQSNGHVKIYSEQGHGTTVKLYLPRAASAPELPAAESGRPAVARGDETILIVEDDALVRDYVVAQVRRLGYRTLSA
SNAAEGLAIIDSPERIDLLFTDVIIPGGKNGRQLAIEAEKRRPGLKVLYTSGYTENAIVHHGRLDADVLLLAKPYLSADL
ARMIRTALEA

Sequences:

>Translated_490_residues
MFLWRRWRDVLFRGVIAGLAGYAAVCGVGRLVAIVDLWLPTAGAGTVIDAVQALLSFGLIALMLKILPQLLVLPTRITLQ
KAYAQLEEEVRQRRAAEAMVRRFQEIEANEAQVRQAQKMEAIGQLTGGVAHDFNNILTVITGTIEILADAVKDKPQLAGI
AAMISAAAERGADLTRHLLAFSRRQPLQPRATDINALVVDAARLLRPTLGEQIEIESMLSHDSAPALIDPSQLSTAILNL
AINARDAMPDGGKLTLETKNITLDEDYARLNRDAKPGGYVMIAVSDTGQGIPASLLDKVFEPFFTTKDVGKGSGLGLSMV
YGFVKQSNGHVKIYSEQGHGTTVKLYLPRAASAPELPAAESGRPAVARGDETILIVEDDALVRDYVVAQVRRLGYRTLSA
SNAAEGLAIIDSPERIDLLFTDVIIPGGKNGRQLAIEAEKRRPGLKVLYTSGYTENAIVHHGRLDADVLLLAKPYLSADL
ARMIRTALEA
>Mature_490_residues
MFLWRRWRDVLFRGVIAGLAGYAAVCGVGRLVAIVDLWLPTAGAGTVIDAVQALLSFGLIALMLKILPQLLVLPTRITLQ
KAYAQLEEEVRQRRAAEAMVRRFQEIEANEAQVRQAQKMEAIGQLTGGVAHDFNNILTVITGTIEILADAVKDKPQLAGI
AAMISAAAERGADLTRHLLAFSRRQPLQPRATDINALVVDAARLLRPTLGEQIEIESMLSHDSAPALIDPSQLSTAILNL
AINARDAMPDGGKLTLETKNITLDEDYARLNRDAKPGGYVMIAVSDTGQGIPASLLDKVFEPFFTTKDVGKGSGLGLSMV
YGFVKQSNGHVKIYSEQGHGTTVKLYLPRAASAPELPAAESGRPAVARGDETILIVEDDALVRDYVVAQVRRLGYRTLSA
SNAAEGLAIIDSPERIDLLFTDVIIPGGKNGRQLAIEAEKRRPGLKVLYTSGYTENAIVHHGRLDADVLLLAKPYLSADL
ARMIRTALEA

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=239, Percent_Identity=29.7071129707113, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788549, Length=251, Percent_Identity=31.8725099601594, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1790300, Length=248, Percent_Identity=29.4354838709677, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081816, Length=380, Percent_Identity=24.2105263157895, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 52961; Mature: 52961

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLWRRWRDVLFRGVIAGLAGYAAVCGVGRLVAIVDLWLPTAGAGTVIDAVQALLSFGLI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
ALMLKILPQLLVLPTRITLQKAYAQLEEEVRQRRAAEAMVRRFQEIEANEAQVRQAQKME
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
AIGQLTGGVAHDFNNILTVITGTIEILADAVKDKPQLAGIAAMISAAAERGADLTRHLLA
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCHHHHHHHHH
FSRRQPLQPRATDINALVVDAARLLRPTLGEQIEIESMLSHDSAPALIDPSQLSTAILNL
HHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEHHHHHCCCCCCCEECHHHHHHHHHHH
AINARDAMPDGGKLTLETKNITLDEDYARLNRDAKPGGYVMIAVSDTGQGIPASLLDKVF
HEECCCCCCCCCEEEEEECCCEECHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHH
EPFFTTKDVGKGSGLGLSMVYGFVKQSNGHVKIYSEQGHGTTVKLYLPRAASAPELPAAE
HHHCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCC
SGRPAVARGDETILIVEDDALVRDYVVAQVRRLGYRTLSASNAAEGLAIIDSPERIDLLF
CCCCCEECCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCEEEEE
TDVIIPGGKNGRQLAIEAEKRRPGLKVLYTSGYTENAIVHHGRLDADVLLLAKPYLSADL
EEEEECCCCCCCEEEEEECCCCCCEEEEEECCCCCCCEEECCCCCCCEEEEECCHHHHHH
ARMIRTALEA
HHHHHHHHCC
>Mature Secondary Structure
MFLWRRWRDVLFRGVIAGLAGYAAVCGVGRLVAIVDLWLPTAGAGTVIDAVQALLSFGLI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
ALMLKILPQLLVLPTRITLQKAYAQLEEEVRQRRAAEAMVRRFQEIEANEAQVRQAQKME
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
AIGQLTGGVAHDFNNILTVITGTIEILADAVKDKPQLAGIAAMISAAAERGADLTRHLLA
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCHHHHHHHHH
FSRRQPLQPRATDINALVVDAARLLRPTLGEQIEIESMLSHDSAPALIDPSQLSTAILNL
HHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEHHHHHCCCCCCCEECHHHHHHHHHHH
AINARDAMPDGGKLTLETKNITLDEDYARLNRDAKPGGYVMIAVSDTGQGIPASLLDKVF
HEECCCCCCCCCEEEEEECCCEECHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHH
EPFFTTKDVGKGSGLGLSMVYGFVKQSNGHVKIYSEQGHGTTVKLYLPRAASAPELPAAE
HHHCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCC
SGRPAVARGDETILIVEDDALVRDYVVAQVRRLGYRTLSASNAAEGLAIIDSPERIDLLF
CCCCCEECCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCEEEEE
TDVIIPGGKNGRQLAIEAEKRRPGLKVLYTSGYTENAIVHHGRLDADVLLLAKPYLSADL
EEEEECCCCCCCEEEEEECCCCCCEEEEEECCCCCCCEEECCCCCCCEEEEECCHHHHHH
ARMIRTALEA
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA