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The map label for this gene is ychM [C]

Identifier: 146342447

GI number: 146342447

Start: 5794091

End: 5795845

Strand: Direct

Name: ychM [C]

Synonym: BRADO5606

Alternate gene names: 146342447

Gene position: 5794091-5795845 (Clockwise)

Preceding gene: 146342446

Following gene: 146342448

Centisome position: 77.7

GC content: 69.0

Gene sequence:

>1755_bases
ATGACTGAGCAACCTCACGACGGCAGCCATCATTGGGCGATGCTGCGCTCGCTGCAGGGCTGGCGGATCAGCACCCTGCC
CGCCGATCTCACCGCCGGGCTGACGCTCGCCGCGATCGCGATCCCCGAGCAGATGGCGACCGCCAAGCTCGGCGGCTTCG
CGCCGGAAACCGGCTTCTTCGCCTTCCTCGCGGGCTCGCTCGGATTCGCGCTGTTCGGCGCCAACCGCTTCCTGTCCTGC
GGCGCTGATTCGACGATCACGCCGATCTTCGCCGGCGGGCTGGCGCTGCTCGCTGCCAGCGGCACGCCCGAATATGGCAG
CATCGCCGCGGCGCTGGCGCTCTTGGTCGGCGTCATGCTGGTGCTGGCCGGCGGCTTCCGGCTCGGCGGCATCGCCAATC
TGCTGTCGGTGCCGGTCACGGTCGGCTTCCTCTCCGGCATCGCGGTGCACATCATCGTGTCGCAACTGCCCGGCGTTCTC
GGCCTGCCCGCGCCGAGCGGATCGACCTTGGCGCGGATCGCGGCCATGGCCGGGGAGCTTGGCAAGACCAACATCTACAC
CCTCATCATCGGCTTCGGCGTGCTCGCGACCGTCGCGGTGTGCGAGCGGATCAGCGCCTGCATCCCGGGGGCGCTGATCG
CGCTCGCCGCCGCCACGATCTTCGTGATCGGTGCCGGGCTCGAAGCCCGCGGTGTCCCGGTCATCGGCGCGATCTCCGGC
GGCGTACCGATGCCGTCGGTGCCGCTGATTGCGCCGGAGCAATGGGTGAAGCTGGTGCCGCTCGCGTTCCTGATCGCCGT
CGTCGTGATGATGCAGACCGCGGCCACGACACGCTCGTTCCCGTCCGAGCCGGATCGTCCGGCCGACGTCGACCGCGATT
TTCTCGGCGCCGGCGCGGGCAGCGTGCTCGCCGGCTTGTTCGGCACGTTTCCGGTCAATGCGAGCCCGCCGCGCACCGGC
ATCGTCGTGGAGACCGGCGGCCGTTCGCAGGTCGCGGGCCTCTCGGCCGCGGTCATCGTGCTGCTGCTCGTGCTGTTCGG
CGCGCGGCTCTTGGCGCACGTCCCGGAAGCGGCGCTCGGCGGCGTTCTGCTGTTCGTTGCGCTGCGCATCATCCGCGTGA
CGCAGATCGTGCAGATCTATCATGCCTCCAAGGGCGAGTTCCTGCTGATCGTCGCCACCGCAGCCGCGATCGTCGTGCTG
CCGATCGAGCAAGGCGTTGCGCTCGGCATCTCGCTGTCGCTGCTGCACGGCATCTGGAGCACGACGCGCGCGCATCTCAT
GATCTTCGAGCGCGTGCCGGACACCACGATCTGGTGGCCGGCGCATCCGCACATCCGCGGCGAGGAGCTGTCGGACATCG
CCGTAGTCGGCTTCCAGGCGCCGCTGAGCTTCCTCAACGCCGCGACCTTCCGCGCCGACCTGCAGCATCTGCTGCAGCAA
CGCCAGCCGCGGCTCCTGGTGCTCGAAGCCAGCGCGATGGTGGAGATCGACTTCACCGCCGCGCAGGCGATGCGCGAGGT
GATCCGGCAATGCAATGAAGATGGGATCGTGTTCGCGGTGGCACGGCTCGAATCGCTGCGCGCACAGGCCGCGTTCGAAC
GCTTCGGCCTGTACGACGTGCTGCCGCGAGATCACGTATTCCACAGCGTCGATCTCGCGCTGCGGAGCCTGCGCGTCGAG
CCTTTGAGCGGTGCGCGTGAGACCAACGGCGCCACCCCACACTCGCGTCATCCCCGCGAAAGCGGGGATCCATAG

Upstream 100 bases:

>100_bases
CGCCTTCATCGATTACCTCGCCGCGGCATTCGCGCCGCTCCCCCCATGGGATCGCGACCTTGGATAAGCACACGCGCTGC
CTGCGCGCGGAGACATCGAC

Downstream 100 bases:

>100_bases
CCACCGGCCGGGCTGCTTGAGCAGGATGGTCGACGTCCAGCCTGCCTCGAACATCGATCACGCGGTACGGGTCCCGGGTC
GGCGCCTGAACGTCGCATCG

Product: sulfate transporter

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 584; Mature: 583

Protein sequence:

>584_residues
MTEQPHDGSHHWAMLRSLQGWRISTLPADLTAGLTLAAIAIPEQMATAKLGGFAPETGFFAFLAGSLGFALFGANRFLSC
GADSTITPIFAGGLALLAASGTPEYGSIAAALALLVGVMLVLAGGFRLGGIANLLSVPVTVGFLSGIAVHIIVSQLPGVL
GLPAPSGSTLARIAAMAGELGKTNIYTLIIGFGVLATVAVCERISACIPGALIALAAATIFVIGAGLEARGVPVIGAISG
GVPMPSVPLIAPEQWVKLVPLAFLIAVVVMMQTAATTRSFPSEPDRPADVDRDFLGAGAGSVLAGLFGTFPVNASPPRTG
IVVETGGRSQVAGLSAAVIVLLLVLFGARLLAHVPEAALGGVLLFVALRIIRVTQIVQIYHASKGEFLLIVATAAAIVVL
PIEQGVALGISLSLLHGIWSTTRAHLMIFERVPDTTIWWPAHPHIRGEELSDIAVVGFQAPLSFLNAATFRADLQHLLQQ
RQPRLLVLEASAMVEIDFTAAQAMREVIRQCNEDGIVFAVARLESLRAQAAFERFGLYDVLPRDHVFHSVDLALRSLRVE
PLSGARETNGATPHSRHPRESGDP

Sequences:

>Translated_584_residues
MTEQPHDGSHHWAMLRSLQGWRISTLPADLTAGLTLAAIAIPEQMATAKLGGFAPETGFFAFLAGSLGFALFGANRFLSC
GADSTITPIFAGGLALLAASGTPEYGSIAAALALLVGVMLVLAGGFRLGGIANLLSVPVTVGFLSGIAVHIIVSQLPGVL
GLPAPSGSTLARIAAMAGELGKTNIYTLIIGFGVLATVAVCERISACIPGALIALAAATIFVIGAGLEARGVPVIGAISG
GVPMPSVPLIAPEQWVKLVPLAFLIAVVVMMQTAATTRSFPSEPDRPADVDRDFLGAGAGSVLAGLFGTFPVNASPPRTG
IVVETGGRSQVAGLSAAVIVLLLVLFGARLLAHVPEAALGGVLLFVALRIIRVTQIVQIYHASKGEFLLIVATAAAIVVL
PIEQGVALGISLSLLHGIWSTTRAHLMIFERVPDTTIWWPAHPHIRGEELSDIAVVGFQAPLSFLNAATFRADLQHLLQQ
RQPRLLVLEASAMVEIDFTAAQAMREVIRQCNEDGIVFAVARLESLRAQAAFERFGLYDVLPRDHVFHSVDLALRSLRVE
PLSGARETNGATPHSRHPRESGDP
>Mature_583_residues
TEQPHDGSHHWAMLRSLQGWRISTLPADLTAGLTLAAIAIPEQMATAKLGGFAPETGFFAFLAGSLGFALFGANRFLSCG
ADSTITPIFAGGLALLAASGTPEYGSIAAALALLVGVMLVLAGGFRLGGIANLLSVPVTVGFLSGIAVHIIVSQLPGVLG
LPAPSGSTLARIAAMAGELGKTNIYTLIIGFGVLATVAVCERISACIPGALIALAAATIFVIGAGLEARGVPVIGAISGG
VPMPSVPLIAPEQWVKLVPLAFLIAVVVMMQTAATTRSFPSEPDRPADVDRDFLGAGAGSVLAGLFGTFPVNASPPRTGI
VVETGGRSQVAGLSAAVIVLLLVLFGARLLAHVPEAALGGVLLFVALRIIRVTQIVQIYHASKGEFLLIVATAAAIVVLP
IEQGVALGISLSLLHGIWSTTRAHLMIFERVPDTTIWWPAHPHIRGEELSDIAVVGFQAPLSFLNAATFRADLQHLLQQR
QPRLLVLEASAMVEIDFTAAQAMREVIRQCNEDGIVFAVARLESLRAQAAFERFGLYDVLPRDHVFHSVDLALRSLRVEP
LSGARETNGATPHSRHPRESGDP

Specific function: Expression in E.coli induces sulfate uptake during early-to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein [H]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI94721253, Length=468, Percent_Identity=25.4273504273504, Blast_Score=129, Evalue=8e-30,
Organism=Homo sapiens, GI94721257, Length=468, Percent_Identity=25.4273504273504, Blast_Score=129, Evalue=8e-30,
Organism=Homo sapiens, GI94721255, Length=468, Percent_Identity=25.4273504273504, Blast_Score=129, Evalue=9e-30,
Organism=Homo sapiens, GI94721259, Length=468, Percent_Identity=25.4273504273504, Blast_Score=129, Evalue=9e-30,
Organism=Homo sapiens, GI4557535, Length=554, Percent_Identity=22.5631768953069, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI16418413, Length=508, Percent_Identity=24.0157480314961, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI217272867, Length=508, Percent_Identity=24.0157480314961, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI39752683, Length=480, Percent_Identity=23.125, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI45827800, Length=480, Percent_Identity=23.125, Blast_Score=109, Evalue=7e-24,
Organism=Homo sapiens, GI4505697, Length=504, Percent_Identity=23.2142857142857, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI16306483, Length=521, Percent_Identity=22.0729366602687, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI20336282, Length=521, Percent_Identity=22.0729366602687, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI45827802, Length=435, Percent_Identity=24.1379310344828, Blast_Score=96, Evalue=9e-20,
Organism=Homo sapiens, GI269784651, Length=478, Percent_Identity=21.7573221757322, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI65506789, Length=404, Percent_Identity=25.2475247524752, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI47131207, Length=508, Percent_Identity=24.4094488188976, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI20336272, Length=508, Percent_Identity=24.4094488188976, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI16418457, Length=519, Percent_Identity=19.4605009633911, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI301601599, Length=519, Percent_Identity=19.4605009633911, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI100913030, Length=496, Percent_Identity=21.7741935483871, Blast_Score=75, Evalue=3e-13,
Organism=Homo sapiens, GI262206105, Length=297, Percent_Identity=24.2424242424242, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI262206075, Length=297, Percent_Identity=24.2424242424242, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI262206069, Length=297, Percent_Identity=24.2424242424242, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI262206063, Length=297, Percent_Identity=24.2424242424242, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI87081859, Length=517, Percent_Identity=24.3713733075435, Blast_Score=74, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17566848, Length=582, Percent_Identity=23.8831615120275, Blast_Score=125, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI86565215, Length=515, Percent_Identity=24.0776699029126, Blast_Score=122, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI17551690, Length=555, Percent_Identity=23.2432432432432, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI86564196, Length=610, Percent_Identity=21.1475409836066, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17562578, Length=642, Percent_Identity=20.8722741433022, Blast_Score=101, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI193203292, Length=493, Percent_Identity=21.0953346855984, Blast_Score=99, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI86565213, Length=274, Percent_Identity=26.2773722627737, Blast_Score=72, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI86565209, Length=245, Percent_Identity=26.530612244898, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI86565211, Length=273, Percent_Identity=25.6410256410256, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI86564876, Length=390, Percent_Identity=21.2820512820513, Blast_Score=69, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6323121, Length=446, Percent_Identity=21.3004484304933, Blast_Score=90, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6319771, Length=428, Percent_Identity=20.7943925233645, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI19922482, Length=523, Percent_Identity=20.6500956022945, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24651449, Length=477, Percent_Identity=20.7547169811321, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24666186, Length=524, Percent_Identity=23.6641221374046, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24649801, Length=540, Percent_Identity=21.2962962962963, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24647160, Length=532, Percent_Identity=21.8045112781955, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI85815873, Length=563, Percent_Identity=20.9591474245115, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21355087, Length=532, Percent_Identity=21.8045112781955, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21358229, Length=468, Percent_Identity=21.5811965811966, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24663084, Length=537, Percent_Identity=23.463687150838, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21357695, Length=537, Percent_Identity=23.463687150838, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21358633, Length=500, Percent_Identity=23.2, Blast_Score=80, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 60981; Mature: 60850

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEQPHDGSHHWAMLRSLQGWRISTLPADLTAGLTLAAIAIPEQMATAKLGGFAPETGFF
CCCCCCCCCHHHHHHHHCCCCEEECCCCHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHH
AFLAGSLGFALFGANRFLSCGADSTITPIFAGGLALLAASGTPEYGSIAAALALLVGVML
HHHHHHHHHHHHCCCHHEECCCCCCCCHHHHCCHHHEECCCCCCHHHHHHHHHHHHHHHH
VLAGGFRLGGIANLLSVPVTVGFLSGIAVHIIVSQLPGVLGLPAPSGSTLARIAAMAGEL
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHCC
GKTNIYTLIIGFGVLATVAVCERISACIPGALIALAAATIFVIGAGLEARGVPVIGAISG
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHEECCCCCCCCCEEEEECC
GVPMPSVPLIAPEQWVKLVPLAFLIAVVVMMQTAATTRSFPSEPDRPADVDRDFLGAGAG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCHH
SVLAGLFGTFPVNASPPRTGIVVETGGRSQVAGLSAAVIVLLLVLFGARLLAHVPEAALG
HHHHHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
GVLLFVALRIIRVTQIVQIYHASKGEFLLIVATAAAIVVLPIEQGVALGISLSLLHGIWS
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHH
TTRAHLMIFERVPDTTIWWPAHPHIRGEELSDIAVVGFQAPLSFLNAATFRADLQHLLQQ
HHHHHEEEEEECCCCEEEECCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHH
RQPRLLVLEASAMVEIDFTAAQAMREVIRQCNEDGIVFAVARLESLRAQAAFERFGLYDV
CCCCEEEEECCEEEEEEHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHCCCHHC
LPRDHVFHSVDLALRSLRVEPLSGARETNGATPHSRHPRESGDP
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TEQPHDGSHHWAMLRSLQGWRISTLPADLTAGLTLAAIAIPEQMATAKLGGFAPETGFF
CCCCCCCCHHHHHHHHCCCCEEECCCCHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHH
AFLAGSLGFALFGANRFLSCGADSTITPIFAGGLALLAASGTPEYGSIAAALALLVGVML
HHHHHHHHHHHHCCCHHEECCCCCCCCHHHHCCHHHEECCCCCCHHHHHHHHHHHHHHHH
VLAGGFRLGGIANLLSVPVTVGFLSGIAVHIIVSQLPGVLGLPAPSGSTLARIAAMAGEL
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHCC
GKTNIYTLIIGFGVLATVAVCERISACIPGALIALAAATIFVIGAGLEARGVPVIGAISG
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHEECCCCCCCCCEEEEECC
GVPMPSVPLIAPEQWVKLVPLAFLIAVVVMMQTAATTRSFPSEPDRPADVDRDFLGAGAG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCHH
SVLAGLFGTFPVNASPPRTGIVVETGGRSQVAGLSAAVIVLLLVLFGARLLAHVPEAALG
HHHHHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
GVLLFVALRIIRVTQIVQIYHASKGEFLLIVATAAAIVVLPIEQGVALGISLSLLHGIWS
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHH
TTRAHLMIFERVPDTTIWWPAHPHIRGEELSDIAVVGFQAPLSFLNAATFRADLQHLLQQ
HHHHHEEEEEECCCCEEEECCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHH
RQPRLLVLEASAMVEIDFTAAQAMREVIRQCNEDGIVFAVARLESLRAQAAFERFGLYDV
CCCCEEEEECCEEEEEEHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHCCCHHC
LPRDHVFHSVDLALRSLRVEPLSGARETNGATPHSRHPRESGDP
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]