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The map label for this gene is ycgM [C]

Identifier: 146342338

GI number: 146342338

Start: 5676540

End: 5677334

Strand: Reverse

Name: ycgM [C]

Synonym: BRADO5494

Alternate gene names: 146342338

Gene position: 5677334-5676540 (Counterclockwise)

Preceding gene: 146342341

Following gene: 146342337

Centisome position: 76.14

GC content: 64.78

Gene sequence:

>795_bases
ATGGCAGAGCCCTCACGCCGCAATCTTCTCGTCGCGGGCAGCGCCGCCGCCGCGGCCGCGCTCCTCACGGACACTCAGCC
TGCCGCAGCCCAGGTCGGACCGAAGCCGATCTTCGCCGTAGCGGCGACGACGATTCCGATCGCTGGCGAGCAGGGCGTGT
TCCCCGTCCGCCGCATCTACTGCATCGGCCGCAACTACGCCGCGCATGCGATCGAGCGCGGCTCCGATCCGAACCGCGAG
CCGCCATTCTTCTTCCAGAAGCCGACGGATGCCATCCAGAACGTCGCGGTCGGTGAGGTCGCCGACCATCCCTATCCGTC
GCTGACCAAGAACTATCACCACGAGGTCGAGCTGGTCGCCGCGCTGAAATCCGGCGGCACCAACATCCCGGTCGAATCCG
CGCTCGACCACGTCTATGGCTATGCGCTCGGCCTCGACATGACCCGGCGCGATCTGCAGAACGGCATGGCCGCCGAGAAG
AAGCCCTGGGAGATCGGCAAGAGCTTCGATCATGCCGCCGTCATCGGCCCGATCCATCCGGTTTCGAACGTCGGCCATTT
CACCAAAGGCGCGATCTCGCTCGCCGTGAACGGGACGGTTCGGCAGAGCTCTGATCTCACCAAGATGATCTGGAGCGTCG
CCGAGCAGATCGCCAAGCTCTCCGAGGCGTTCGAGCTCAAGGCCGGCGACATCATCTATTCCGGCACGCCGGAGAATGTC
GGACCCGTCGTGAAGGGCGACGTGCTGCTGTGCAAGCTCGAGGGCCTGCCGGATATGTCGATCAAGATCGTTTGA

Upstream 100 bases:

>100_bases
TGTGGCGCTGGCATAATGGATATGCTTATCAGTCAAGACGCGCCGAAGCGCCGAAGAACAACAGGCTGCCTGGGAGGCGG
CCGATCTCAGGAGGAACCGA

Downstream 100 bases:

>100_bases
GGATGAAGGCGGCTGGCCTCGTAGCCCGCATGAGCGCAGCGACATGCGGGTTCTCCGAAGGCACCGGTGAGATCCCGGAT
ATCGCTTGCGCTCATCCGGG

Product: putative fumarylacetoacetate hydrolase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MAEPSRRNLLVAGSAAAAAALLTDTQPAAAQVGPKPIFAVAATTIPIAGEQGVFPVRRIYCIGRNYAAHAIERGSDPNRE
PPFFFQKPTDAIQNVAVGEVADHPYPSLTKNYHHEVELVAALKSGGTNIPVESALDHVYGYALGLDMTRRDLQNGMAAEK
KPWEIGKSFDHAAVIGPIHPVSNVGHFTKGAISLAVNGTVRQSSDLTKMIWSVAEQIAKLSEAFELKAGDIIYSGTPENV
GPVVKGDVLLCKLEGLPDMSIKIV

Sequences:

>Translated_264_residues
MAEPSRRNLLVAGSAAAAAALLTDTQPAAAQVGPKPIFAVAATTIPIAGEQGVFPVRRIYCIGRNYAAHAIERGSDPNRE
PPFFFQKPTDAIQNVAVGEVADHPYPSLTKNYHHEVELVAALKSGGTNIPVESALDHVYGYALGLDMTRRDLQNGMAAEK
KPWEIGKSFDHAAVIGPIHPVSNVGHFTKGAISLAVNGTVRQSSDLTKMIWSVAEQIAKLSEAFELKAGDIIYSGTPENV
GPVVKGDVLLCKLEGLPDMSIKIV
>Mature_263_residues
AEPSRRNLLVAGSAAAAAALLTDTQPAAAQVGPKPIFAVAATTIPIAGEQGVFPVRRIYCIGRNYAAHAIERGSDPNREP
PFFFQKPTDAIQNVAVGEVADHPYPSLTKNYHHEVELVAALKSGGTNIPVESALDHVYGYALGLDMTRRDLQNGMAAEKK
PWEIGKSFDHAAVIGPIHPVSNVGHFTKGAISLAVNGTVRQSSDLTKMIWSVAEQIAKLSEAFELKAGDIIYSGTPENVG
PVVKGDVLLCKLEGLPDMSIKIV

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI215422413, Length=204, Percent_Identity=36.7647058823529, Blast_Score=127, Evalue=9e-30,
Organism=Homo sapiens, GI13654274, Length=207, Percent_Identity=36.231884057971, Blast_Score=127, Evalue=9e-30,
Organism=Homo sapiens, GI66348062, Length=200, Percent_Identity=36.5, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI156231349, Length=215, Percent_Identity=31.1627906976744, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI40786394, Length=218, Percent_Identity=31.1926605504587, Blast_Score=88, Evalue=6e-18,
Organism=Escherichia coli, GI1787428, Length=206, Percent_Identity=34.9514563106796, Blast_Score=121, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI17557057, Length=194, Percent_Identity=31.4432989690722, Blast_Score=108, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6324161, Length=225, Percent_Identity=31.1111111111111, Blast_Score=100, Evalue=4e-22,
Organism=Drosophila melanogaster, GI28572127, Length=216, Percent_Identity=30.5555555555556, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI28571789, Length=207, Percent_Identity=26.5700483091787, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 28084; Mature: 27953

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEPSRRNLLVAGSAAAAAALLTDTQPAAAQVGPKPIFAVAATTIPIAGEQGVFPVRRIY
CCCCCCCCEEEECCHHHHHHHHCCCCCHHHHCCCCCEEEEEEEEEECCCCCCCCCEEEEE
CIGRNYAAHAIERGSDPNREPPFFFQKPTDAIQNVAVGEVADHPYPSLTKNYHHEVELVA
EECCCHHHHHHHCCCCCCCCCCEEEECCHHHHHHCHHHHHCCCCCCCHHHCCCHHHHHEE
ALKSGGTNIPVESALDHVYGYALGLDMTRRDLQNGMAAEKKPWEIGKSFDHAAVIGPIHP
HHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCHHHCCCCCCEEEECCCCC
VSNVGHFTKGAISLAVNGTVRQSSDLTKMIWSVAEQIAKLSEAFELKAGDIIYSGTPENV
HHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCC
GPVVKGDVLLCKLEGLPDMSIKIV
CCCEECCEEEEEECCCCCCEEEEC
>Mature Secondary Structure 
AEPSRRNLLVAGSAAAAAALLTDTQPAAAQVGPKPIFAVAATTIPIAGEQGVFPVRRIY
CCCCCCCEEEECCHHHHHHHHCCCCCHHHHCCCCCEEEEEEEEEECCCCCCCCCEEEEE
CIGRNYAAHAIERGSDPNREPPFFFQKPTDAIQNVAVGEVADHPYPSLTKNYHHEVELVA
EECCCHHHHHHHCCCCCCCCCCEEEECCHHHHHHCHHHHHCCCCCCCHHHCCCHHHHHEE
ALKSGGTNIPVESALDHVYGYALGLDMTRRDLQNGMAAEKKPWEIGKSFDHAAVIGPIHP
HHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCHHHCCCCCCEEEECCCCC
VSNVGHFTKGAISLAVNGTVRQSSDLTKMIWSVAEQIAKLSEAFELKAGDIIYSGTPENV
HHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCC
GPVVKGDVLLCKLEGLPDMSIKIV
CCCEECCEEEEEECCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]