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The map label for this gene is sufC [H]

Identifier: 146342291

GI number: 146342291

Start: 5632809

End: 5633570

Strand: Reverse

Name: sufC [H]

Synonym: BRADO5446

Alternate gene names: 146342291

Gene position: 5633570-5632809 (Counterclockwise)

Preceding gene: 146342292

Following gene: 146342290

Centisome position: 75.55

GC content: 65.88

Gene sequence:

>762_bases
ATGACGGCCTTGCTCGAAATCAAGGGGCTCCATGCCGAGATCTCCGGTGGTCGCAAGATCATCCAGGGTCTGGACCTCAC
CGTGAACAAGGGCGAGATCCACGCCATCATGGGCCCGAACGGCGCCGGCAAGTCTACACTCTCCTACGTGCTCGCCGGCA
AGCCCGGCTATGAGATCACCGCCGGTGAGGTCTATCTCAACGGCGAGGATCTGCTGGCGATGTCGGCCGACGAGCGCGCC
GCGAAGGGCGTGTTCCTGGCGTTCCAGTATCCGCTGGAGATCCCGGGTGTCGCGACCCTGACCTTCCTGCGTGCCGCCTT
CAACGCCCAGCGCAAGGCGCGCGGCGAGGAGGAGCTGTCCTCGCCCGACCTCATCAAGCGCGTGCGCGAGATCGCCAAGA
CCCTGAACATCGACTCGGAGATGCTGAAGCGGCCGCTTAATGTCGGCTTCTCCGGCGGCGAGAAGAAGCGCAACGAGACC
CTGCAGATGGCGCTGCTGCAGCCCTCGCTCTGCGTGCTCGACGAGACCGACTCGGGCCTCGACATCGACGCGCTGAAGGT
GGTGGCCAACGGCGTCAACGCGCTGCGCTCGGCCGAGCGCGGCATGATCGTAATCACCCACTACCAGCGGCTGCTCGACT
ACATCGTGCCGGATATCGTCCACGTCTTCGCGGCGGGCCGTATCGTCCGGACGGGGGCTGCGGATCTCGCGCGCGAGCTC
GAGGCGACCGGCTACGCGCAGTACCAGAGCGAAGCGGCGTAA

Upstream 100 bases:

>100_bases
TGGAGTTCGCGGTCGAGGCGCAGAAGCTGATCTCGATCAGCCTCGAAGGTTCAGTCGGATAAGGACGTCGCGCGCGGCGA
CAACAGATGAGGAGTGTTCG

Downstream 100 bases:

>100_bases
GGGGCGGGGAGCACGAGCATGGGCGTCGCGATCCGCAAGACCAAGGCCGAGCTGGGATTGGCCGATCTGTACCAGGTCGC
CCGCCGCTATCTGCCGGGCG

Product: Fe-S cluster assembly ABC transporter ATP binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MTALLEIKGLHAEISGGRKIIQGLDLTVNKGEIHAIMGPNGAGKSTLSYVLAGKPGYEITAGEVYLNGEDLLAMSADERA
AKGVFLAFQYPLEIPGVATLTFLRAAFNAQRKARGEEELSSPDLIKRVREIAKTLNIDSEMLKRPLNVGFSGGEKKRNET
LQMALLQPSLCVLDETDSGLDIDALKVVANGVNALRSAERGMIVITHYQRLLDYIVPDIVHVFAAGRIVRTGAADLAREL
EATGYAQYQSEAA

Sequences:

>Translated_253_residues
MTALLEIKGLHAEISGGRKIIQGLDLTVNKGEIHAIMGPNGAGKSTLSYVLAGKPGYEITAGEVYLNGEDLLAMSADERA
AKGVFLAFQYPLEIPGVATLTFLRAAFNAQRKARGEEELSSPDLIKRVREIAKTLNIDSEMLKRPLNVGFSGGEKKRNET
LQMALLQPSLCVLDETDSGLDIDALKVVANGVNALRSAERGMIVITHYQRLLDYIVPDIVHVFAAGRIVRTGAADLAREL
EATGYAQYQSEAA
>Mature_252_residues
TALLEIKGLHAEISGGRKIIQGLDLTVNKGEIHAIMGPNGAGKSTLSYVLAGKPGYEITAGEVYLNGEDLLAMSADERAA
KGVFLAFQYPLEIPGVATLTFLRAAFNAQRKARGEEELSSPDLIKRVREIAKTLNIDSEMLKRPLNVGFSGGEKKRNETL
QMALLQPSLCVLDETDSGLDIDALKVVANGVNALRSAERGMIVITHYQRLLDYIVPDIVHVFAAGRIVRTGAADLARELE
ATGYAQYQSEAA

Specific function: Has low ATPase activity. The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May f

COG id: COG0396

COG function: function code O; ABC-type transport system involved in Fe-S cluster assembly, ATPase component

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI11967971, Length=236, Percent_Identity=27.9661016949153, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI42741659, Length=221, Percent_Identity=30.316742081448, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI4505771, Length=215, Percent_Identity=29.3023255813954, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI9961252, Length=214, Percent_Identity=28.9719626168224, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1787972, Length=243, Percent_Identity=55.9670781893004, Blast_Score=285, Evalue=2e-78,
Organism=Escherichia coli, GI1787370, Length=234, Percent_Identity=25.6410256410256, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1786319, Length=214, Percent_Identity=29.4392523364486, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1789593, Length=194, Percent_Identity=26.8041237113402, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI87082267, Length=177, Percent_Identity=26.5536723163842, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI87081709, Length=253, Percent_Identity=25.296442687747, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1787500, Length=260, Percent_Identity=30.7692307692308, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR010230 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 27296; Mature: 27165

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALLEIKGLHAEISGGRKIIQGLDLTVNKGEIHAIMGPNGAGKSTLSYVLAGKPGYEIT
CCEEEEECCCEEECCCCHHHHHCCCEEEECCEEEEEECCCCCCCHHHEEEEECCCCCEEE
AGEVYLNGEDLLAMSADERAAKGVFLAFQYPLEIPGVATLTFLRAAFNAQRKARGEEELS
ECEEEECCCCEEEECCCCHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHCC
SPDLIKRVREIAKTLNIDSEMLKRPLNVGFSGGEKKRNETLQMALLQPSLCVLDETDSGL
CCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCC
DIDALKVVANGVNALRSAERGMIVITHYQRLLDYIVPDIVHVFAAGRIVRTGAADLAREL
CHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHH
EATGYAQYQSEAA
HHCCCHHHHCCCC
>Mature Secondary Structure 
TALLEIKGLHAEISGGRKIIQGLDLTVNKGEIHAIMGPNGAGKSTLSYVLAGKPGYEIT
CEEEEECCCEEECCCCHHHHHCCCEEEECCEEEEEECCCCCCCHHHEEEEECCCCCEEE
AGEVYLNGEDLLAMSADERAAKGVFLAFQYPLEIPGVATLTFLRAAFNAQRKARGEEELS
ECEEEECCCCEEEECCCCHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHCC
SPDLIKRVREIAKTLNIDSEMLKRPLNVGFSGGEKKRNETLQMALLQPSLCVLDETDSGL
CCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCC
DIDALKVVANGVNALRSAERGMIVITHYQRLLDYIVPDIVHVFAAGRIVRTGAADLAREL
CHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHH
EATGYAQYQSEAA
HHCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 10322040 [H]