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The map label for this gene is iscA [C]

Identifier: 146342271

GI number: 146342271

Start: 5615203

End: 5615523

Strand: Reverse

Name: iscA [C]

Synonym: BRADO5425

Alternate gene names: 146342271

Gene position: 5615523-5615203 (Counterclockwise)

Preceding gene: 146342273

Following gene: 146342270

Centisome position: 75.31

GC content: 62.62

Gene sequence:

>321_bases
ATGATCAACCTGACTGACAGCGCCGTCAACGCAGTGCGCAACGCGATCACGACCTCCGACAAGCCGGTCGACGGTCTCCG
GATCATGGTCGAAGCCGGCGGCTGCGCCGGGCTCAAATACAACATGGGCCTCGTCAGCGGCAGCGAGCCCGAGGACACCG
TGATCGAGCGCGAGGGTGTGCGCGTGCTCGTCGATCACAAGAGCCTCGAATATCTCGAGGGCACGACGATCGATTTCGTC
GTTGCGCTGGAAGGCTCCGGCTTCACCTTCGAGAACCCCAACGCCAAGTCGAGCTGCGGTTGCGGCAAGTCCTTCGCTTG
A

Upstream 100 bases:

>100_bases
AGAGACAACGCGAAAAGCCGTGGTCTTTCAGGCGATTGTTCGATGGCACGAGACTTGCCAATTCCGTTCGCAACAGCCGG
ATGGGAAAGGCCAGACGATG

Downstream 100 bases:

>100_bases
CCCCTTCAACATCTGAAAGAGCTGATATCATGCTGGTCGAAACCCAGGGCGTCGTCGAAGCGCCGGCTCAGATGAGCGAA
CGCGAGCGGATCATCCGCGC

Product: Iron-binding protein IscA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 106; Mature: 106

Protein sequence:

>106_residues
MINLTDSAVNAVRNAITTSDKPVDGLRIMVEAGGCAGLKYNMGLVSGSEPEDTVIEREGVRVLVDHKSLEYLEGTTIDFV
VALEGSGFTFENPNAKSSCGCGKSFA

Sequences:

>Translated_106_residues
MINLTDSAVNAVRNAITTSDKPVDGLRIMVEAGGCAGLKYNMGLVSGSEPEDTVIEREGVRVLVDHKSLEYLEGTTIDFV
VALEGSGFTFENPNAKSSCGCGKSFA
>Mature_106_residues
MINLTDSAVNAVRNAITTSDKPVDGLRIMVEAGGCAGLKYNMGLVSGSEPEDTVIEREGVRVLVDHKSLEYLEGTTIDFV
VALEGSGFTFENPNAKSSCGCGKSFA

Specific function: Unknown

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family [H]

Homologues:

Organism=Homo sapiens, GI160420328, Length=107, Percent_Identity=39.2523364485981, Blast_Score=77, Evalue=4e-15,
Organism=Homo sapiens, GI52426768, Length=105, Percent_Identity=38.0952380952381, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1786351, Length=105, Percent_Identity=42.8571428571429, Blast_Score=95, Evalue=7e-22,
Organism=Escherichia coli, GI1788877, Length=104, Percent_Identity=46.1538461538462, Blast_Score=92, Evalue=6e-21,
Organism=Escherichia coli, GI1787974, Length=104, Percent_Identity=33.6538461538462, Blast_Score=71, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193209025, Length=105, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI25146411, Length=105, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71998452, Length=108, Percent_Identity=33.3333333333333, Blast_Score=61, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6323001, Length=105, Percent_Identity=31.4285714285714, Blast_Score=74, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6325324, Length=104, Percent_Identity=35.5769230769231, Blast_Score=64, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24642263, Length=106, Percent_Identity=38.6792452830189, Blast_Score=76, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870 [H]

Pfam domain/function: PF01521 Fe-S_biosyn [H]

EC number: NA

Molecular weight: Translated: 11174; Mature: 11174

Theoretical pI: Translated: 4.34; Mature: 4.34

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINLTDSAVNAVRNAITTSDKPVDGLRIMVEAGGCAGLKYNMGLVSGSEPEDTVIEREGV
CCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCEEECCEECCCCCCCCCEEECCCC
RVLVDHKSLEYLEGTTIDFVVALEGSGFTFENPNAKSSCGCGKSFA
EEEEECCCCCCCCCCEEEEEEEECCCCCEECCCCCCCCCCCCCCCC
>Mature Secondary Structure
MINLTDSAVNAVRNAITTSDKPVDGLRIMVEAGGCAGLKYNMGLVSGSEPEDTVIEREGV
CCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCEEECCEECCCCCCCCCEEECCCC
RVLVDHKSLEYLEGTTIDFVVALEGSGFTFENPNAKSSCGCGKSFA
EEEEECCCCCCCCCCEEEEEEEECCCCCEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11157954; 12597275 [H]