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The map label for this gene is catB2 [H]

Identifier: 146342215

GI number: 146342215

Start: 5573729

End: 5574391

Strand: Direct

Name: catB2 [H]

Synonym: BRADO5367

Alternate gene names: 146342215

Gene position: 5573729-5574391 (Clockwise)

Preceding gene: 146342205

Following gene: 146342216

Centisome position: 74.75

GC content: 63.8

Gene sequence:

>663_bases
ATGGTCGGCAAATCGCTTTCCATCGATCCCACCGTCGATCCCAGCGCCAAGCTCCATGAGACGCATCTCGGCGCGTATAC
CGAGGTTGGTGCGCGAACCATCCTTCACGAGGTGACGATGGGCGACTACTCCTATGTCGTCAACGACGCGCAGATCACCT
ATACGACCATTGGCAAGTTCTGCTCGATCGCGGCGCTGACCCGGATCAATCCCGGCAACCACCCGATGTATCGCGCGACC
CAGGCCCACTTCACCTATCGCGCCAGCGCCTACTTTCCCGGCGAAGCCGACGATGCCGAGTTCTTCGCCTGGCGCAGGCG
CCATCACGTCGACATCGGCCACGACGTCTGGATCGGCCATGGCGCGATCGTGCTGCCGGGACGGACCATCGGCACCGGCG
CCGTGATCGCCGCGGGTGCCATCGTCACCAAGGACGTGCCGGCCTACACGATCGTCGCCGGCAATCCCGCCCGGATCATC
AAGCGGCGGTTTCCGATCGAAATCGAGCAGCGTCTCGTCAATCTGGCATGGTGGGACTGGGACCATGAGACGCTCCGCGC
GGCGCTACCGGATTTCCGGCAGCTCGAGATCGGCCAATTCCTGGACAAATACGAGACGGCTCTCGACGGCAGGCGCCAGG
TGCGGCAGAGTGCCGCGCAATGA

Upstream 100 bases:

>100_bases
GCTCATCCATACGCGCATCGACGTTGTCATGGTGATGTCACGCGAATGTCATGATGGACGCCCTACAGGTTCTGCTTGAT
CTCAAGGGAATAAGAAAGAC

Downstream 100 bases:

>100_bases
CAGACATCTCCATCTCCTCGGGCCGCTGTCTGATCGGCGCCGACTTCGCTGACACCTCTCTGACCGTATCCGAAGGCGTG
ATCGACCGGCTCGATGTCCC

Product: putative acetyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MVGKSLSIDPTVDPSAKLHETHLGAYTEVGARTILHEVTMGDYSYVVNDAQITYTTIGKFCSIAALTRINPGNHPMYRAT
QAHFTYRASAYFPGEADDAEFFAWRRRHHVDIGHDVWIGHGAIVLPGRTIGTGAVIAAGAIVTKDVPAYTIVAGNPARII
KRRFPIEIEQRLVNLAWWDWDHETLRAALPDFRQLEIGQFLDKYETALDGRRQVRQSAAQ

Sequences:

>Translated_220_residues
MVGKSLSIDPTVDPSAKLHETHLGAYTEVGARTILHEVTMGDYSYVVNDAQITYTTIGKFCSIAALTRINPGNHPMYRAT
QAHFTYRASAYFPGEADDAEFFAWRRRHHVDIGHDVWIGHGAIVLPGRTIGTGAVIAAGAIVTKDVPAYTIVAGNPARII
KRRFPIEIEQRLVNLAWWDWDHETLRAALPDFRQLEIGQFLDKYETALDGRRQVRQSAAQ
>Mature_220_residues
MVGKSLSIDPTVDPSAKLHETHLGAYTEVGARTILHEVTMGDYSYVVNDAQITYTTIGKFCSIAALTRINPGNHPMYRAT
QAHFTYRASAYFPGEADDAEFFAWRRRHHVDIGHDVWIGHGAIVLPGRTIGTGAVIAAGAIVTKDVPAYTIVAGNPARII
KRRFPIEIEQRLVNLAWWDWDHETLRAALPDFRQLEIGQFLDKYETALDGRRQVRQSAAQ

Specific function: This enzyme is an effector of chloramphenicol resistance in bacteria [H]

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1786664, Length=53, Percent_Identity=60.377358490566, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1788345, Length=126, Percent_Identity=34.1269841269841, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1786537, Length=75, Percent_Identity=41.3333333333333, Blast_Score=61, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322243, Length=53, Percent_Identity=47.1698113207547, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.28 [H]

Molecular weight: Translated: 24569; Mature: 24569

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGKSLSIDPTVDPSAKLHETHLGAYTEVGARTILHEVTMGDYSYVVNDAQITYTTIGKF
CCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHCCCEEEEEECCEEEEEHHHHH
CSIAALTRINPGNHPMYRATQAHFTYRASAYFPGEADDAEFFAWRRRHHVDIGHDVWIGH
HHHHHHEEECCCCCCCEEEEEEEEEEEEEEECCCCCCCHHHHHHHHHCCCCCCCEEEECC
GAIVLPGRTIGTGAVIAAGAIVTKDVPAYTIVAGNPARIIKRRFPIEIEQRLVNLAWWDW
CEEEECCCCCCCCHHHHHCEEEECCCCEEEEEECCHHHHHHHCCCHHHHHHHHHHHEECC
DHETLRAALPDFRQLEIGQFLDKYETALDGRRQVRQSAAQ
CHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVGKSLSIDPTVDPSAKLHETHLGAYTEVGARTILHEVTMGDYSYVVNDAQITYTTIGKF
CCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHCCCEEEEEECCEEEEEHHHHH
CSIAALTRINPGNHPMYRATQAHFTYRASAYFPGEADDAEFFAWRRRHHVDIGHDVWIGH
HHHHHHEEECCCCCCCEEEEEEEEEEEEEEECCCCCCCHHHHHHHHHCCCCCCCEEEECC
GAIVLPGRTIGTGAVIAAGAIVTKDVPAYTIVAGNPARIIKRRFPIEIEQRLVNLAWWDW
CEEEECCCCCCCCHHHHHCEEEECCCCEEEEEECCHHHHHHHCCCHHHHHHHHHHHEECC
DHETLRAALPDFRQLEIGQFLDKYETALDGRRQVRQSAAQ
CHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1314803 [H]