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The map label for this gene is fucA [H]

Identifier: 146341688

GI number: 146341688

Start: 4989925

End: 4990713

Strand: Reverse

Name: fucA [H]

Synonym: BRADO4793

Alternate gene names: 146341688

Gene position: 4990713-4989925 (Counterclockwise)

Preceding gene: 146341689

Following gene: 146341687

Centisome position: 66.93

GC content: 63.75

Gene sequence:

>789_bases
ATGAATCGCGAGGAACGACAGCTCCGCGAGACCATCATCGCCAAGTGCCGGTGGATGAACGCCTCGGGTCTGAATCAGGG
CACGTCCGGCAATATCTCGGCCCGCTACAAGGACCGAATGCTGATTACGCCGTCGGCGACACCCTATGATTCGATGAAGC
CGGAGATGATCGCATCGATGCCGCTCGACGGCGAATATGGCTCCTGGGAAGGGCCGTTGAAGCCGTCGACGGAATGGCGC
TTCCATCTGGACATCATGCGCGGACGCCCGGATGTCGGCGGCGTCGTGCATACGCATTCGACCTACGCCACCGTGCTTGC
GATTGCGCGCAAGCCGATTCCGGCCTGCCACTACATGATGGCGGCGTTCGGCGGCACCGACATCCGTTGCGCCGGCTATG
CGCGTTTCGGCACGGCCGAACTGTCCGAGCTGGCGCTGGAAGCGCTGAAGGGACGCAACGGCTGCCTGCTCGCCAACCAT
GGCATGATCGCCGTCGGCGCCAATCTCGACAAGGCGATGTGGCTCGCGGTCGAGCTCGAGACCATCGCGAAGCAGTATTA
TCTTTCGCTCGCGCTGGGACAGCCGCACATCCTGGGCGATGCCGAGATCGCCGAGACGGCGCAGGGCTTTTCGACCTACG
GGCTGCAGGACCAGAAGACGACAAAGTCAGCGAAGCCCGTCAAGAAGGCGGTCAAGGTTGCTGCCAAGCCAGCTGCCAAA
GCCGGCACCAAGACGCGTGCGGCCGCAGCCCGGCGCAAGCCCGAGACGAAGCGTAGCGCGACGCGATGA

Upstream 100 bases:

>100_bases
CCGAACCGTCACCATCGCCGCCGACCAGGCGGCCGAAGAGGTTCGCCGCTATCTCGCCGGCGAGCCGCCGCTCAATCCCT
GCTGACGAAAGGTTTTCCAA

Downstream 100 bases:

>100_bases
ACGCACCGGTCTCACGCAGCGTATCCGATGATGGCTTGTTGGACCTCGCCGTCATCGGCGGCGGCATCAATGGCGCTGGT
GTCGCCCGTGATGCCGCCGG

Product: L-fuculose-1-phosphate aldolase

Products: NA

Alternate protein names: L-fuculose-1-phosphate aldolase [H]

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MNREERQLRETIIAKCRWMNASGLNQGTSGNISARYKDRMLITPSATPYDSMKPEMIASMPLDGEYGSWEGPLKPSTEWR
FHLDIMRGRPDVGGVVHTHSTYATVLAIARKPIPACHYMMAAFGGTDIRCAGYARFGTAELSELALEALKGRNGCLLANH
GMIAVGANLDKAMWLAVELETIAKQYYLSLALGQPHILGDAEIAETAQGFSTYGLQDQKTTKSAKPVKKAVKVAAKPAAK
AGTKTRAAAARRKPETKRSATR

Sequences:

>Translated_262_residues
MNREERQLRETIIAKCRWMNASGLNQGTSGNISARYKDRMLITPSATPYDSMKPEMIASMPLDGEYGSWEGPLKPSTEWR
FHLDIMRGRPDVGGVVHTHSTYATVLAIARKPIPACHYMMAAFGGTDIRCAGYARFGTAELSELALEALKGRNGCLLANH
GMIAVGANLDKAMWLAVELETIAKQYYLSLALGQPHILGDAEIAETAQGFSTYGLQDQKTTKSAKPVKKAVKVAAKPAAK
AGTKTRAAAARRKPETKRSATR
>Mature_262_residues
MNREERQLRETIIAKCRWMNASGLNQGTSGNISARYKDRMLITPSATPYDSMKPEMIASMPLDGEYGSWEGPLKPSTEWR
FHLDIMRGRPDVGGVVHTHSTYATVLAIARKPIPACHYMMAAFGGTDIRCAGYARFGTAELSELALEALKGRNGCLLANH
GMIAVGANLDKAMWLAVELETIAKQYYLSLALGQPHILGDAEIAETAQGFSTYGLQDQKTTKSAKPVKKAVKVAAKPAAK
AGTKTRAAAARRKPETKRSATR

Specific function: Fucose metabolism; third step. [C]

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family. AraD/FucA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789164, Length=217, Percent_Identity=47.4654377880184, Blast_Score=198, Evalue=2e-52,
Organism=Escherichia coli, GI1789094, Length=206, Percent_Identity=29.6116504854369, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1790642, Length=197, Percent_Identity=30.4568527918782, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790008, Length=195, Percent_Identity=31.2820512820513, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303
- InterPro:   IPR004782 [H]

Pfam domain/function: PF00596 Aldolase_II [H]

EC number: =4.1.2.17 [H]

Molecular weight: Translated: 28512; Mature: 28512

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNREERQLRETIIAKCRWMNASGLNQGTSGNISARYKDRMLITPSATPYDSMKPEMIASM
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCEEEECCCCCCCCCCCCHHHHCC
PLDGEYGSWEGPLKPSTEWRFHLDIMRGRPDVGGVVHTHSTYATVLAIARKPIPACHYMM
CCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCEEEECHHHHHHHHHHCCCCHHHHHHH
AAFGGTDIRCAGYARFGTAELSELALEALKGRNGCLLANHGMIAVGANLDKAMWLAVELE
HHCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCEEEECCCEEEEECCCCCCEEEEHHHH
TIAKQYYLSLALGQPHILGDAEIAETAQGFSTYGLQDQKTTKSAKPVKKAVKVAAKPAAK
HHHHHHHHHHCCCCCCEECCHHHHHHHCCHHHCCCCCCHHCCHHHHHHHHHHHHHCCCHH
AGTKTRAAAARRKPETKRSATR
CCCHHHHHHHHCCCCCHHCCCC
>Mature Secondary Structure
MNREERQLRETIIAKCRWMNASGLNQGTSGNISARYKDRMLITPSATPYDSMKPEMIASM
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCEEEECCCCCCCCCCCCHHHHCC
PLDGEYGSWEGPLKPSTEWRFHLDIMRGRPDVGGVVHTHSTYATVLAIARKPIPACHYMM
CCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCEEEECHHHHHHHHHHCCCCHHHHHHH
AAFGGTDIRCAGYARFGTAELSELALEALKGRNGCLLANHGMIAVGANLDKAMWLAVELE
HHCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCEEEECCCEEEEECCCCCCEEEEHHHH
TIAKQYYLSLALGQPHILGDAEIAETAQGFSTYGLQDQKTTKSAKPVKKAVKVAAKPAAK
HHHHHHHHHHCCCCCCEECCHHHHHHHCCHHHCCCCCCHHCCHHHHHHHHHHHHHCCCHH
AGTKTRAAAARRKPETKRSATR
CCCHHHHHHHHCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]