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The map label for this gene is ndhM [H]

Identifier: 146341669

GI number: 146341669

Start: 4966790

End: 4967812

Strand: Reverse

Name: ndhM [H]

Synonym: BRADO4774

Alternate gene names: 146341669

Gene position: 4967812-4966790 (Counterclockwise)

Preceding gene: 146341670

Following gene: 146341668

Centisome position: 66.62

GC content: 67.74

Gene sequence:

>1023_bases
ATGACGAGGCACCGCGGCCGCGGCATGGCGGCGATCAACTATCCCATCGGCATGAATCTCGGCGGCGATCCGAGCCAGGC
ACTGGTGCATTCGAACCCGAGCGGCAAGTTCACGGTTGCGCTGTCGTCTATCGATCTGGGCCAAGGCATGAAGTCGGTGA
CGCGGCAGATCTGCGCCGAGACGCTCGGCGTGCCCGTCGAGGACGTCTATGTCGACACCGCGGATTCCGACACCGGGCCG
CATTGCATGGGCTCGTTCGCCTCGCGCGGCACGCATCGCGTCGGCAACGCCGTGATGGCCGCAGCCAAGGAGGCGCGCGG
CGTCATGATGGAGGCGGCCGCCGAGGAGCTCGAAGTCAATGCCAGCGACCTCGAAACCGACGGTCGCGGCAACATCCATG
TCAAGGGCGCGCCGCACCGCTCGATCTCGGTCAAGGACGTCGCCATCGCCGCGCAGTTCCGCCAGGGCAAGACGATATCG
GGGCGCGGCATCTTCCTGGTGCCGCTGTCGGACGTCGATCCCGAGACCGGCGAGATGTCGCCCGCGACCTGCTACGCGCA
TGCCTGTCTGGTCGCCGAGGTCGAGGTCGACGACGAAACCGGCGAAGTCGGCGTGATCAGGATGGACTCGGCCTATGAGC
TCGGCCGCGCGCTCAATCCGCGACTCGTCGAGCAGCAGCTGGTCGGCGGCGCCTGGATGGGCATGAGCCACGCGCTGTAT
GAGACGACCGAGCCGTATTATCCCGATCCCAAGCAGGGCCCGCGCGACTTCGTCGAATATCTGATGCCGGGTCCCGGCGA
CATCTGCCCGCACGACATTGCCGTGCTGGAGCGGCCGGCGCCTGACGGTCCCTTCGGGGGCAAGGGCCCCGGCGAGATGT
GCGCCAATCCGGTGCTGCCGGCGATCGCCAACGCGATCTTCAACGCCGTCGGCGTGCGCATCGACGAGCTGCCGATCACG
CCGGAAAAGGTGCTGCGCGCGATCAAGGCCCAGGGCGGCGCTCGGCCGCAGATCCGGCGGTAA

Upstream 100 bases:

>100_bases
CCACAGCCCGAACCGCCGCCACCACCGCCGCCTTCGGCGCCATCGTCGGGGCACGGCGCCACCCGGTTCTCATCCGTGTT
CGGCACGAGGAGGCGCTGAG

Downstream 100 bases:

>100_bases
CGGCGCATGGTGGTCCGCAGCAGCATCGTCGGCATCGACTCGCCGCAGGCGCTGGAAAAGGCGCTGCGTGCGGCCTATTA
CCTCGCCGATGACGGGCTCT

Product: putative oxidoreductase subunit aerobic-type carbon monoxide dehydrogenase large subunit CoxL/CutL

Products: NA

Alternate protein names: NDH; Nicotinic acid hydroxylase medium molybdopterin subunit; NAH [H]

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MTRHRGRGMAAINYPIGMNLGGDPSQALVHSNPSGKFTVALSSIDLGQGMKSVTRQICAETLGVPVEDVYVDTADSDTGP
HCMGSFASRGTHRVGNAVMAAAKEARGVMMEAAAEELEVNASDLETDGRGNIHVKGAPHRSISVKDVAIAAQFRQGKTIS
GRGIFLVPLSDVDPETGEMSPATCYAHACLVAEVEVDDETGEVGVIRMDSAYELGRALNPRLVEQQLVGGAWMGMSHALY
ETTEPYYPDPKQGPRDFVEYLMPGPGDICPHDIAVLERPAPDGPFGGKGPGEMCANPVLPAIANAIFNAVGVRIDELPIT
PEKVLRAIKAQGGARPQIRR

Sequences:

>Translated_340_residues
MTRHRGRGMAAINYPIGMNLGGDPSQALVHSNPSGKFTVALSSIDLGQGMKSVTRQICAETLGVPVEDVYVDTADSDTGP
HCMGSFASRGTHRVGNAVMAAAKEARGVMMEAAAEELEVNASDLETDGRGNIHVKGAPHRSISVKDVAIAAQFRQGKTIS
GRGIFLVPLSDVDPETGEMSPATCYAHACLVAEVEVDDETGEVGVIRMDSAYELGRALNPRLVEQQLVGGAWMGMSHALY
ETTEPYYPDPKQGPRDFVEYLMPGPGDICPHDIAVLERPAPDGPFGGKGPGEMCANPVLPAIANAIFNAVGVRIDELPIT
PEKVLRAIKAQGGARPQIRR
>Mature_339_residues
TRHRGRGMAAINYPIGMNLGGDPSQALVHSNPSGKFTVALSSIDLGQGMKSVTRQICAETLGVPVEDVYVDTADSDTGPH
CMGSFASRGTHRVGNAVMAAAKEARGVMMEAAAEELEVNASDLETDGRGNIHVKGAPHRSISVKDVAIAAQFRQGKTISG
RGIFLVPLSDVDPETGEMSPATCYAHACLVAEVEVDDETGEVGVIRMDSAYELGRALNPRLVEQQLVGGAWMGMSHALYE
TTEPYYPDPKQGPRDFVEYLMPGPGDICPHDIAVLERPAPDGPFGGKGPGEMCANPVLPAIANAIFNAVGVRIDELPITP
EKVLRAIKAQGGARPQIRR

Specific function: Catalyzes the hydroxylation of nicotinate to 6- hydroxynicotinate. Also active against 2-pyrazinecarboxylic acid, but inactive against other nicotinate analogs [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789246, Length=333, Percent_Identity=31.8318318318318, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1789230, Length=338, Percent_Identity=31.9526627218935, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1786478, Length=309, Percent_Identity=31.0679611650485, Blast_Score=96, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24647193, Length=317, Percent_Identity=28.391167192429, Blast_Score=75, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008274 [H]

Pfam domain/function: PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.17.1.5 [H]

Molecular weight: Translated: 36051; Mature: 35920

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRHRGRGMAAINYPIGMNLGGDPSQALVHSNPSGKFTVALSSIDLGQGMKSVTRQICAE
CCCCCCCCEEEEECCEECCCCCCCCCCEEECCCCCEEEEEEECCCHHCCHHHHHHHHHHH
TLGVPVEDVYVDTADSDTGPHCMGSFASRGTHRVGNAVMAAAKEARGVMMEAAAEELEVN
HHCCCHHHEEEECCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ASDLETDGRGNIHVKGAPHRSISVKDVAIAAQFRQGKTISGRGIFLVPLSDVDPETGEMS
HHHCCCCCCCCEEEECCCCCCCCHHHHEEEHHHHCCCEECCCCEEEEECCCCCCCCCCCC
PATCYAHACLVAEVEVDDETGEVGVIRMDSAYELGRALNPRLVEQQLVGGAWMGMSHALY
CHHHHEEEEEEEEEEECCCCCCEEEEEECCHHHHHHCCCHHHHHHHHHCHHHHCHHHHHH
ETTEPYYPDPKQGPRDFVEYLMPGPGDICPHDIAVLERPAPDGPFGGKGPGEMCANPVLP
HCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHEEECCCCCCCCCCCCCHHHHCCCHHH
AIANAIFNAVGVRIDELPITPEKVLRAIKAQGGARPQIRR
HHHHHHHHHHCCEEECCCCCHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TRHRGRGMAAINYPIGMNLGGDPSQALVHSNPSGKFTVALSSIDLGQGMKSVTRQICAE
CCCCCCCEEEEECCEECCCCCCCCCCEEECCCCCEEEEEEECCCHHCCHHHHHHHHHHH
TLGVPVEDVYVDTADSDTGPHCMGSFASRGTHRVGNAVMAAAKEARGVMMEAAAEELEVN
HHCCCHHHEEEECCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ASDLETDGRGNIHVKGAPHRSISVKDVAIAAQFRQGKTISGRGIFLVPLSDVDPETGEMS
HHHCCCCCCCCEEEECCCCCCCCHHHHEEEHHHHCCCEECCCCEEEEECCCCCCCCCCCC
PATCYAHACLVAEVEVDDETGEVGVIRMDSAYELGRALNPRLVEQQLVGGAWMGMSHALY
CHHHHEEEEEEEEEEECCCCCCEEEEEECCHHHHHHCCCHHHHHHHHHCHHHHCHHHHHH
ETTEPYYPDPKQGPRDFVEYLMPGPGDICPHDIAVLERPAPDGPFGGKGPGEMCANPVLP
HCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHEEECCCCCCCCCCCCCHHHHCCCHHH
AIANAIFNAVGVRIDELPITPEKVLRAIKAQGGARPQIRR
HHHHHHHHHHCCEEECCCCCHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA