BacMap

Definition	Bradyrhizobium sp. ORS278 chromosome, complete genome.
Accession	NC_009445
Length	7,456,587

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The map label for this gene is fabG [C]

Identifier: 146341661

GI number: 146341661

Start: 4959030

End: 4959779

Strand: Reverse

Name: fabG [C]

Synonym: BRADO4765

Alternate gene names: 146341661

Gene position: 4959779-4959030 (Counterclockwise)

Preceding gene: 146341663

Following gene: 146341660

Centisome position: 66.52

GC content: 66.53

Gene sequence:

>750_bases
ATGCTGCTCAGCGGCAAGACGGCGATCATCTCGGGCGCGGCCTCGAAGCGCGGCATCGGACTTGCGACCGCGCGGCGGTT
CGCCGCCGAAGGCGCGAAAGTCGCGATCCTCGACATCGATGCGGCGGCTGCGGCCGAGGCGGCGGCCTCGCTCGGCGACG
GTCATATCGGGCTCGGCTGCAACGTCGCCGACAAGACCTCGTGCAACGACGCGGTGGCGCAGGCGATCCGTCAGTTCGGC
GTCATCGACATCCTCATCAACAATGCCGGCATCACCCAGCCGGTCAAGCTGCTCGACATCAAAGAAGAAGACTGGGAGCG
CATCCAGAACGTCAACCTCAAGGGCGTGCTGTTCCTGTCGCAGGCGGTGATCCCGCACATGCGCGCGCGTAAATCGGGCT
CGATCGCCTGCATGTCCTCGGTCTCGGCGCAGCGCGGCGGCGGCATCTTCGGCGGGCCGCATTACTCGGCCGCCAAGGCC
GGCGTGCTCGGCCTTGCCAAGGCGATGGCGCGCGAGTTCGGCATCGACGGCATCCGCGTCAACTGCGTCACCCCGGGCCT
GATCGGCACCGATATCACCGCCGGCAAGCTGACCGACGAGATGAAGGCCAAGATCCTCGAGGGCATTCCGCTCAACCGTC
TCGGCACCGCCGAGGACGTCGCCGGCATCTACACCTTCCTGGCCTCTGATCTCTCCGCCTACGTCACGGGCGCGGTGATC
GATGTCAACGGCGGCATGCTGATCCACTAA

Upstream 100 bases:

>100_bases
GAACCAGATTCATCTATCCATGACAACTGCGCGTTTGTCGCCGCCGGTCCGGCCCGCCATGGTTAAGCCCAACACAACGA
CACTTTGGGGAGGACCAAGC

Downstream 100 bases:

>100_bases
ACAAGGTCTCACACGATGGACATCGCAACCAATCGGCTCGCCAACGCGCCGACGCTGGCGCAGCGCGCCTACAACATCCG
CCGCAACGCGCTGCGCATGG

Product: putative short chain dehydrogenase/reductase

Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MLLSGKTAIISGAASKRGIGLATARRFAAEGAKVAILDIDAAAAAEAAASLGDGHIGLGCNVADKTSCNDAVAQAIRQFG
VIDILINNAGITQPVKLLDIKEEDWERIQNVNLKGVLFLSQAVIPHMRARKSGSIACMSSVSAQRGGGIFGGPHYSAAKA
GVLGLAKAMAREFGIDGIRVNCVTPGLIGTDITAGKLTDEMKAKILEGIPLNRLGTAEDVAGIYTFLASDLSAYVTGAVI
DVNGGMLIH

Sequences:

>Translated_249_residues
MLLSGKTAIISGAASKRGIGLATARRFAAEGAKVAILDIDAAAAAEAAASLGDGHIGLGCNVADKTSCNDAVAQAIRQFG
VIDILINNAGITQPVKLLDIKEEDWERIQNVNLKGVLFLSQAVIPHMRARKSGSIACMSSVSAQRGGGIFGGPHYSAAKA
GVLGLAKAMAREFGIDGIRVNCVTPGLIGTDITAGKLTDEMKAKILEGIPLNRLGTAEDVAGIYTFLASDLSAYVTGAVI
DVNGGMLIH
>Mature_249_residues
MLLSGKTAIISGAASKRGIGLATARRFAAEGAKVAILDIDAAAAAEAAASLGDGHIGLGCNVADKTSCNDAVAQAIRQFG
VIDILINNAGITQPVKLLDIKEEDWERIQNVNLKGVLFLSQAVIPHMRARKSGSIACMSSVSAQRGGGIFGGPHYSAAKA
GVLGLAKAMAREFGIDGIRVNCVTPGLIGTDITAGKLTDEMKAKILEGIPLNRLGTAEDVAGIYTFLASDLSAYVTGAVI
DVNGGMLIH

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=258, Percent_Identity=37.5968992248062, Blast_Score=140, Evalue=7e-34,
Organism=Homo sapiens, GI32483357, Length=249, Percent_Identity=36.144578313253, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI126723750, Length=253, Percent_Identity=35.5731225296443, Blast_Score=125, Evalue=4e-29,
Organism=Homo sapiens, GI66933014, Length=224, Percent_Identity=36.1607142857143, Blast_Score=123, Evalue=1e-28,
Organism=Homo sapiens, GI40254992, Length=230, Percent_Identity=33.0434782608696, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI5031737, Length=248, Percent_Identity=34.6774193548387, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI19923817, Length=262, Percent_Identity=31.2977099236641, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI4503301, Length=214, Percent_Identity=30.8411214953271, Blast_Score=98, Evalue=7e-21,
Organism=Homo sapiens, GI33667109, Length=196, Percent_Identity=34.1836734693878, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI7705925, Length=258, Percent_Identity=30.2325581395349, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI4758504, Length=260, Percent_Identity=29.2307692307692, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI126723191, Length=186, Percent_Identity=34.4086021505376, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI59889578, Length=227, Percent_Identity=29.9559471365639, Blast_Score=91, Evalue=7e-19,
Organism=Homo sapiens, GI31542939, Length=217, Percent_Identity=29.4930875576037, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI4504505, Length=194, Percent_Identity=33.5051546391753, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI10190704, Length=253, Percent_Identity=31.2252964426877, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI210032110, Length=228, Percent_Identity=25.8771929824561, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI224922801, Length=178, Percent_Identity=30.3370786516854, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI40807363, Length=206, Percent_Identity=30.0970873786408, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI83715985, Length=260, Percent_Identity=27.3076923076923, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI4503817, Length=213, Percent_Identity=27.6995305164319, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI302344755, Length=112, Percent_Identity=34.8214285714286, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI40254986, Length=195, Percent_Identity=31.7948717948718, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI20149619, Length=205, Percent_Identity=27.3170731707317, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI109715829, Length=233, Percent_Identity=27.0386266094421, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI210032112, Length=225, Percent_Identity=23.5555555555556, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI7706318, Length=222, Percent_Identity=26.1261261261261, Blast_Score=64, Evalue=9e-11,
Organism=Escherichia coli, GI1787335, Length=249, Percent_Identity=43.3734939759036, Blast_Score=171, Evalue=3e-44,
Organism=Escherichia coli, GI87082100, Length=255, Percent_Identity=37.2549019607843, Blast_Score=137, Evalue=5e-34,
Organism=Escherichia coli, GI1789208, Length=248, Percent_Identity=34.6774193548387, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI87082160, Length=250, Percent_Identity=35.6, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1790717, Length=250, Percent_Identity=32.8, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1787905, Length=246, Percent_Identity=34.5528455284553, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI2367365, Length=244, Percent_Identity=32.7868852459016, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789378, Length=254, Percent_Identity=30.7086614173228, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI2367175, Length=258, Percent_Identity=31.3953488372093, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788459, Length=227, Percent_Identity=29.0748898678414, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI1786812, Length=254, Percent_Identity=29.5275590551181, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1788891, Length=242, Percent_Identity=27.6859504132231, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789057, Length=239, Percent_Identity=29.2887029288703, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1787820, Length=192, Percent_Identity=27.6041666666667, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787545, Length=265, Percent_Identity=29.4339622641509, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1787526, Length=252, Percent_Identity=25.3968253968254, Blast_Score=68, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI25147288, Length=247, Percent_Identity=37.6518218623482, Blast_Score=154, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI17555706, Length=255, Percent_Identity=38.4313725490196, Blast_Score=149, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17560676, Length=251, Percent_Identity=30.6772908366534, Blast_Score=120, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI17544670, Length=269, Percent_Identity=35.6877323420074, Blast_Score=119, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17561402, Length=253, Percent_Identity=32.4110671936759, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17551412, Length=264, Percent_Identity=32.5757575757576, Blast_Score=103, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI71994600, Length=251, Percent_Identity=32.6693227091633, Blast_Score=100, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17559104, Length=263, Percent_Identity=32.319391634981, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17538480, Length=263, Percent_Identity=32.319391634981, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17562910, Length=262, Percent_Identity=32.0610687022901, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17565030, Length=269, Percent_Identity=33.8289962825279, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71994604, Length=252, Percent_Identity=30.952380952381, Blast_Score=94, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17560332, Length=264, Percent_Identity=31.0606060606061, Blast_Score=94, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17562904, Length=265, Percent_Identity=32.8301886792453, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17568967, Length=194, Percent_Identity=34.020618556701, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17538486, Length=264, Percent_Identity=31.0606060606061, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17560150, Length=267, Percent_Identity=30.7116104868914, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17562906, Length=272, Percent_Identity=29.7794117647059, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI72000259, Length=260, Percent_Identity=29.2307692307692, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17562990, Length=261, Percent_Identity=29.5019157088123, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI193204405, Length=265, Percent_Identity=28.6792452830189, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17538182, Length=255, Percent_Identity=28.6274509803922, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17563726, Length=260, Percent_Identity=28.8461538461538, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17561272, Length=238, Percent_Identity=31.5126050420168, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17536025, Length=252, Percent_Identity=29.3650793650794, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17562908, Length=264, Percent_Identity=28.7878787878788, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI115534694, Length=164, Percent_Identity=31.7073170731707, Blast_Score=78, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17531453, Length=265, Percent_Identity=30.5660377358491, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17567345, Length=196, Percent_Identity=27.0408163265306, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17536651, Length=256, Percent_Identity=29.6875, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17508895, Length=197, Percent_Identity=27.9187817258883, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17564282, Length=202, Percent_Identity=30.1980198019802, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71982365, Length=191, Percent_Identity=26.1780104712042, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17508651, Length=261, Percent_Identity=30.6513409961686, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560220, Length=269, Percent_Identity=27.5092936802974, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193203117, Length=198, Percent_Identity=26.7676767676768, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193203115, Length=196, Percent_Identity=26.530612244898, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17558628, Length=197, Percent_Identity=29.9492385786802, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=190, Percent_Identity=34.7368421052632, Blast_Score=94, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6324126, Length=256, Percent_Identity=30.859375, Blast_Score=91, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24639444, Length=249, Percent_Identity=39.3574297188755, Blast_Score=157, Evalue=6e-39,
Organism=Drosophila melanogaster, GI21355319, Length=249, Percent_Identity=34.9397590361446, Blast_Score=142, Evalue=3e-34,
Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=35.8565737051793, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24644339, Length=256, Percent_Identity=32.03125, Blast_Score=111, Evalue=5e-25,
Organism=Drosophila melanogaster, GI18859837, Length=215, Percent_Identity=34.4186046511628, Blast_Score=100, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24643142, Length=247, Percent_Identity=31.9838056680162, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI17737361, Length=259, Percent_Identity=28.957528957529, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI28571526, Length=250, Percent_Identity=30.8, Blast_Score=95, Evalue=6e-20,
Organism=Drosophila melanogaster, GI21357041, Length=250, Percent_Identity=30.8, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24641232, Length=220, Percent_Identity=27.2727272727273, Blast_Score=81, Evalue=5e-16,
Organism=Drosophila melanogaster, GI281364892, Length=197, Percent_Identity=30.9644670050761, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24649181, Length=206, Percent_Identity=24.2718446601942, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI21357673, Length=195, Percent_Identity=29.2307692307692, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24644337, Length=177, Percent_Identity=32.2033898305085, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI221331218, Length=202, Percent_Identity=30.6930693069307, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21358495, Length=216, Percent_Identity=28.7037037037037, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24665243, Length=202, Percent_Identity=30.6930693069307, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI221331216, Length=203, Percent_Identity=31.0344827586207, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24665247, Length=203, Percent_Identity=31.0344827586207, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24581726, Length=179, Percent_Identity=25.6983240223464, Blast_Score=67, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100 [C]

Molecular weight: Translated: 25541; Mature: 25541

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLSGKTAIISGAASKRGIGLATARRFAAEGAKVAILDIDAAAAAEAAASLGDGHIGLGC
CCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCEEEEEECCHHHHHHHHHHCCCCCEEECC
NVADKTSCNDAVAQAIRQFGVIDILINNAGITQPVKLLDIKEEDWERIQNVNLKGVLFLS
CCCCCCCCCHHHHHHHHHCCEEEEEEECCCCCCCEEEEECCHHHHHHHHCCCCEEEEEHH
QAVIPHMRARKSGSIACMSSVSAQRGGGIFGGPHYSAAKAGVLGLAKAMAREFGIDGIRV
HHHHHHHHHCCCCCEEEHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEE
NCVTPGLIGTDITAGKLTDEMKAKILEGIPLNRLGTAEDVAGIYTFLASDLSAYVTGAVI
EEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEE
DVNGGMLIH
EECCCEEEC
>Mature Secondary Structure
MLLSGKTAIISGAASKRGIGLATARRFAAEGAKVAILDIDAAAAAEAAASLGDGHIGLGC
CCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCEEEEEECCHHHHHHHHHHCCCCCEEECC
NVADKTSCNDAVAQAIRQFGVIDILINNAGITQPVKLLDIKEEDWERIQNVNLKGVLFLS
CCCCCCCCCHHHHHHHHHCCEEEEEEECCCCCCCEEEEECCHHHHHHHHCCCCEEEEEHH
QAVIPHMRARKSGSIACMSSVSAQRGGGIFGGPHYSAAKAGVLGLAKAMAREFGIDGIRV
HHHHHHHHHCCCCCEEEHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEE
NCVTPGLIGTDITAGKLTDEMKAKILEGIPLNRLGTAEDVAGIYTFLASDLSAYVTGAVI
EEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEE
DVNGGMLIH
EECCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]

Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]