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The map label for this gene is cysS [H]

Identifier: 146341598

GI number: 146341598

Start: 4889325

End: 4890734

Strand: Reverse

Name: cysS [H]

Synonym: BRADO4699

Alternate gene names: 146341598

Gene position: 4890734-4889325 (Counterclockwise)

Preceding gene: 146341601

Following gene: 146341597

Centisome position: 65.59

GC content: 66.1

Gene sequence:

>1410_bases
ATGGACTTGCGTTTGTACGACACCGCGTCGCGGGAGAAGCGCCCCTTCGTGCCGCTCGATCCGAACAATGTCCGCATGTA
TGTCTGCGGACCTACGGTCTACGACTTCGCCCATATCGGCAACGCGCGGCCCGTGATCGTCTTCGACGTGCTGTTCCGCC
TGCTGCGCCGCATCTATGGCGCCGAGCACGTGACCTATGTCCGCAACATCACCGACGTGGACGACAAGATCAACGCGCGC
GCCGCGCGCGACTATCCCGGCCTGCCGCTGAACGAGGCGATCCGGAAGGTCACCGAGGTGACGGCCAATCAGTTCCACAG
CGACACGGCGGCGCTTGGCAGTCTGCCGCCGACCTTCGAGCCGCGCGCGACCGACTTCGTTCTGCCGCGTCCCGACGGCA
AGGCGGATATGGTGACCTTGATCGAGCAGTTGATCGCGCGCGGCCATGCGTATGAAGCCGGCGGCGAGGTGCTGTTCGAC
ACCCGCTCGATGCCGGACTATGGCGCGCTATCGGGTCGCAAGCTCGAAGATCAACTCGCCGGCGCGCGCGTTGCGGTCGA
TGCGCACAAGAAGAACCCCGCCGACTTCGTGCTGTGGAAGCAGTCGTCGGCGGACGAGCCGGGCTGGGACAGCCCGTGGG
GGCGAGGCCGCCCCGGCTGGCACATCGAATGCTCGGCGATGAGCGCGGCCTATCTCGGCGACGTCTTCGACATCCATGGC
GGCGGGCTCGACCTGATCTTCCCGCATCATGAGAACGAGATTGCGCAGTCGCGCTGCGCCCATGGCACCTCGGTGATGGC
GAACTACTGGCTGCACAATGAGTTCGTGCAGGTCGAGGGCGCGAAGATGTCGAAGAGCCTCGGCAACTTCGTTACCATCC
GCGACCTGTTGGCGGACTGGCCGGGCGAGGTGCTGCGCCTGAACATGCTCAAGATGCACTATCGCTCGCCGGCCGACTGG
ACGGTGAAGGGCCTGGAGGAGAGCGCGAAGACGCTCGACGACTGGTACCGCGTCGCGGCCGATGCGCCGGGCGAGCAGCC
GGAGCCGGCGATCATCAATGCGTTGCTCGACGACATCAACACGCCGCTGATGATCGCGGAGTTGCACGCGCTTCGTGCGC
GGGCTGCTTCCGGGAGCGAGGTTGATCGCGCTGCATTCGCCGGCTCGCTCCGTTATTTCGGCTTCCTGTCGGAGACGGCA
ACGCTGTGGGAAGCTCGGAAGCAGCAAGCCAAAGGCGTCGACGCCGCCGAAGTCGAGGGCCTGATCGCTGAGCGCACGGC
CGCCCGCGCGCGCAAGGACTTCAAGGAGTCCGATCGTCTGCGCGACGAGCTCGCCGCGATGGGCGTCGTGCTCAAGGACG
GCAAGGGGGCCGACGGCAAGCCGGTGACGACGTGGGAGATCGCGCGATGA

Upstream 100 bases:

>100_bases
TGGCCGCCCTTCATCCGGGCCGTCATCTGGCGGAGGACACCCGCTGCGTCTCGTCCGGCGAGACGCAGGCATTCGGGACT
GAGGCATTCGGGGACTGACC

Downstream 100 bases:

>100_bases
AGAAGCCCGACACGCCGTTTCCGCGGCACTGGCTGTACTACATCGTGCTCAAGCTCGCGGTGATCGCGGCCGCAGTGGCG
CTGGTGACGAAGCTCTACGG

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 469; Mature: 469

Protein sequence:

>469_residues
MDLRLYDTASREKRPFVPLDPNNVRMYVCGPTVYDFAHIGNARPVIVFDVLFRLLRRIYGAEHVTYVRNITDVDDKINAR
AARDYPGLPLNEAIRKVTEVTANQFHSDTAALGSLPPTFEPRATDFVLPRPDGKADMVTLIEQLIARGHAYEAGGEVLFD
TRSMPDYGALSGRKLEDQLAGARVAVDAHKKNPADFVLWKQSSADEPGWDSPWGRGRPGWHIECSAMSAAYLGDVFDIHG
GGLDLIFPHHENEIAQSRCAHGTSVMANYWLHNEFVQVEGAKMSKSLGNFVTIRDLLADWPGEVLRLNMLKMHYRSPADW
TVKGLEESAKTLDDWYRVAADAPGEQPEPAIINALLDDINTPLMIAELHALRARAASGSEVDRAAFAGSLRYFGFLSETA
TLWEARKQQAKGVDAAEVEGLIAERTAARARKDFKESDRLRDELAAMGVVLKDGKGADGKPVTTWEIAR

Sequences:

>Translated_469_residues
MDLRLYDTASREKRPFVPLDPNNVRMYVCGPTVYDFAHIGNARPVIVFDVLFRLLRRIYGAEHVTYVRNITDVDDKINAR
AARDYPGLPLNEAIRKVTEVTANQFHSDTAALGSLPPTFEPRATDFVLPRPDGKADMVTLIEQLIARGHAYEAGGEVLFD
TRSMPDYGALSGRKLEDQLAGARVAVDAHKKNPADFVLWKQSSADEPGWDSPWGRGRPGWHIECSAMSAAYLGDVFDIHG
GGLDLIFPHHENEIAQSRCAHGTSVMANYWLHNEFVQVEGAKMSKSLGNFVTIRDLLADWPGEVLRLNMLKMHYRSPADW
TVKGLEESAKTLDDWYRVAADAPGEQPEPAIINALLDDINTPLMIAELHALRARAASGSEVDRAAFAGSLRYFGFLSETA
TLWEARKQQAKGVDAAEVEGLIAERTAARARKDFKESDRLRDELAAMGVVLKDGKGADGKPVTTWEIAR
>Mature_469_residues
MDLRLYDTASREKRPFVPLDPNNVRMYVCGPTVYDFAHIGNARPVIVFDVLFRLLRRIYGAEHVTYVRNITDVDDKINAR
AARDYPGLPLNEAIRKVTEVTANQFHSDTAALGSLPPTFEPRATDFVLPRPDGKADMVTLIEQLIARGHAYEAGGEVLFD
TRSMPDYGALSGRKLEDQLAGARVAVDAHKKNPADFVLWKQSSADEPGWDSPWGRGRPGWHIECSAMSAAYLGDVFDIHG
GGLDLIFPHHENEIAQSRCAHGTSVMANYWLHNEFVQVEGAKMSKSLGNFVTIRDLLADWPGEVLRLNMLKMHYRSPADW
TVKGLEESAKTLDDWYRVAADAPGEQPEPAIINALLDDINTPLMIAELHALRARAASGSEVDRAAFAGSLRYFGFLSETA
TLWEARKQQAKGVDAAEVEGLIAERTAARARKDFKESDRLRDELAAMGVVLKDGKGADGKPVTTWEIAR

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=526, Percent_Identity=33.0798479087452, Blast_Score=233, Evalue=3e-61,
Organism=Homo sapiens, GI21269877, Length=324, Percent_Identity=33.3333333333333, Blast_Score=183, Evalue=3e-46,
Organism=Homo sapiens, GI10835051, Length=324, Percent_Identity=33.3333333333333, Blast_Score=183, Evalue=3e-46,
Organism=Homo sapiens, GI62240992, Length=324, Percent_Identity=33.3333333333333, Blast_Score=183, Evalue=3e-46,
Organism=Homo sapiens, GI303304987, Length=324, Percent_Identity=33.3333333333333, Blast_Score=183, Evalue=4e-46,
Organism=Escherichia coli, GI1786737, Length=482, Percent_Identity=43.1535269709544, Blast_Score=347, Evalue=8e-97,
Organism=Caenorhabditis elegans, GI17509797, Length=260, Percent_Identity=36.5384615384615, Blast_Score=163, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17509795, Length=260, Percent_Identity=36.5384615384615, Blast_Score=163, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6324082, Length=324, Percent_Identity=33.3333333333333, Blast_Score=172, Evalue=7e-44,
Organism=Drosophila melanogaster, GI19922218, Length=345, Percent_Identity=37.6811594202899, Blast_Score=207, Evalue=2e-53,
Organism=Drosophila melanogaster, GI19922364, Length=237, Percent_Identity=40.9282700421941, Blast_Score=180, Evalue=2e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 51982; Mature: 51982

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLRLYDTASREKRPFVPLDPNNVRMYVCGPTVYDFAHIGNARPVIVFDVLFRLLRRIYG
CCEEECCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHCCCCCCCHHHHHHHHHHHHHHC
AEHVTYVRNITDVDDKINARAARDYPGLPLNEAIRKVTEVTANQFHSDTAALGSLPPTFE
CCHHHHHHCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCC
PRATDFVLPRPDGKADMVTLIEQLIARGHAYEAGGEVLFDTRSMPDYGALSGRKLEDQLA
CCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHC
GARVAVDAHKKNPADFVLWKQSSADEPGWDSPWGRGRPGWHIECSAMSAAYLGDVFDIHG
CCEEEEECCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHHCCCEEECC
GGLDLIFPHHENEIAQSRCAHGTSVMANYWLHNEFVQVEGAKMSKSLGNFVTIRDLLADW
CCEEEEECCCCCHHHHHHHCCCHHHHHHHHHCCEEEEECCHHHHHHHCCHHHHHHHHHHC
PGEVLRLNMLKMHYRSPADWTVKGLEESAKTLDDWYRVAADAPGEQPEPAIINALLDDIN
CHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCC
TPLMIAELHALRARAASGSEVDRAAFAGSLRYFGFLSETATLWEARKQQAKGVDAAEVEG
CCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
LIAERTAARARKDFKESDRLRDELAAMGVVLKDGKGADGKPVTTWEIAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCCCCCCEEECCC
>Mature Secondary Structure
MDLRLYDTASREKRPFVPLDPNNVRMYVCGPTVYDFAHIGNARPVIVFDVLFRLLRRIYG
CCEEECCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHCCCCCCCHHHHHHHHHHHHHHC
AEHVTYVRNITDVDDKINARAARDYPGLPLNEAIRKVTEVTANQFHSDTAALGSLPPTFE
CCHHHHHHCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCC
PRATDFVLPRPDGKADMVTLIEQLIARGHAYEAGGEVLFDTRSMPDYGALSGRKLEDQLA
CCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHC
GARVAVDAHKKNPADFVLWKQSSADEPGWDSPWGRGRPGWHIECSAMSAAYLGDVFDIHG
CCEEEEECCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHHCCCEEECC
GGLDLIFPHHENEIAQSRCAHGTSVMANYWLHNEFVQVEGAKMSKSLGNFVTIRDLLADW
CCEEEEECCCCCHHHHHHHCCCHHHHHHHHHCCEEEEECCHHHHHHHCCHHHHHHHHHHC
PGEVLRLNMLKMHYRSPADWTVKGLEESAKTLDDWYRVAADAPGEQPEPAIINALLDDIN
CHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCC
TPLMIAELHALRARAASGSEVDRAAFAGSLRYFGFLSETATLWEARKQQAKGVDAAEVEG
CCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
LIAERTAARARKDFKESDRLRDELAAMGVVLKDGKGADGKPVTTWEIAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA