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The map label for this gene is ybdL [H]

Identifier: 146341581

GI number: 146341581

Start: 4870715

End: 4871878

Strand: Reverse

Name: ybdL [H]

Synonym: BRADO4682

Alternate gene names: 146341581

Gene position: 4871878-4870715 (Counterclockwise)

Preceding gene: 146341582

Following gene: 146341580

Centisome position: 65.34

GC content: 64.6

Gene sequence:

>1164_bases
ATGATTTCGCAGAATAAGGTCTTCGCCGATCTGCCCGTCACCATCTTCGAGCAGATGTCGCAGCTCGCGCGCGACAACAA
CGCCATCAATCTGGGGCAGGGCTTTCCCGACGATCCCGGTCCGGAGGACATCCGCCGCGCCGCTGCGGACGCGGTGTTGA
ATGGCTACAACCAGTATCCTTCGATGATGGGCCTGCCGGAGCTGCGCCAGGCCATCGCCGCGCATTACAAGCACTGGCAC
AAGCTCGATCTCGACCCGATGAGCGAGGTGATGGTCACCTCCGGCGGCACCGAGGCGCTGACCTCGGCGATCCTGTCCGT
GGTCGAGCCGGGCGATGAGGTCATCTGCTTCCAGCCAGTCTACGATTCCTACCTCCCGATCATCCGCCAGGCCGGCGGCA
TTCCAAAACTGCTGCGGCTGGAGCCGCCGCATTGGCGGCTGTCGGAGGAGATGCTGCGCTCGGCGTTCTCCGCGAAGACC
AAGGCCGTGCTGTTCAACAATCCGCTGAACCCGGCGGCCGTGGTCTATCCGCGCGAGGATCTCGAGCTGCTCGCCCGCTT
CTGCCAGGATTTCGACGCGGTCGCGATCTGCGACGAGGTCTGGGAGCACGTGGTGTTCGACGGCCGCGAGCACATTCCGC
TGATCACCATTCCCGGCATGCGCGATCGCACCATCAAGGTCGGCTCGGCCGGCAAGATTTTCTCGCTGACGGGCTGGAAG
ATCGGCTTCGTCTGCGCTGCGCCGCAGCTTTTGCGCGTCGCCGCCAAGGTGCATCAGTTCCTGACCTTCACGACCGCGCC
GAACCTGCAGACGGCCGTGGCCTACGGCCTCGGCAAGTCCGACGACTATTTCATCAACATGCGTGCCGAACTCGCGCGCA
GCCGCGACCGGCTCACAGCGGGACTCGAACGCCTCGGCTTCCCCGTGCTGAAGGCGCAGGGGACGTACTTCCTCACGGTC
GACCTGTCGCCGCTCGGCCTCAACGAAACCGACGAGCAGTTCTGCCGGCGCATCGTCCACGATTACAAGGTGGCGGCGAT
CCCGGTGTCGGCATTCTACGAGAAGGATGCGGTGACCTCGGTCGTCCGCTTCTGCTTCGCCAAGAAGGACGCCACGCTCG
ACACGGCGCTGGAGCGCCTGTCCGATGCCATCCACCGACGCTAG

Upstream 100 bases:

>100_bases
GCAATCCGCGGGCATGCCGTACGACAAGCACCTGCAAGGCGGGATGCTCGGCTGGAAGGCGGCCGGCCTGCCGATCAAGA
CCGGCGGCTGACACCCGATC

Downstream 100 bases:

>100_bases
GAGATGAAGGACATGACGCGCGGCTGCATTCGCTCGGCTCTGGCCCTGGCGGCCGCAGTACTGACGCTCTCAGCTGCGGC
AGCTGAGGAGCGCGTCGTGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MISQNKVFADLPVTIFEQMSQLARDNNAINLGQGFPDDPGPEDIRRAAADAVLNGYNQYPSMMGLPELRQAIAAHYKHWH
KLDLDPMSEVMVTSGGTEALTSAILSVVEPGDEVICFQPVYDSYLPIIRQAGGIPKLLRLEPPHWRLSEEMLRSAFSAKT
KAVLFNNPLNPAAVVYPREDLELLARFCQDFDAVAICDEVWEHVVFDGREHIPLITIPGMRDRTIKVGSAGKIFSLTGWK
IGFVCAAPQLLRVAAKVHQFLTFTTAPNLQTAVAYGLGKSDDYFINMRAELARSRDRLTAGLERLGFPVLKAQGTYFLTV
DLSPLGLNETDEQFCRRIVHDYKVAAIPVSAFYEKDAVTSVVRFCFAKKDATLDTALERLSDAIHRR

Sequences:

>Translated_387_residues
MISQNKVFADLPVTIFEQMSQLARDNNAINLGQGFPDDPGPEDIRRAAADAVLNGYNQYPSMMGLPELRQAIAAHYKHWH
KLDLDPMSEVMVTSGGTEALTSAILSVVEPGDEVICFQPVYDSYLPIIRQAGGIPKLLRLEPPHWRLSEEMLRSAFSAKT
KAVLFNNPLNPAAVVYPREDLELLARFCQDFDAVAICDEVWEHVVFDGREHIPLITIPGMRDRTIKVGSAGKIFSLTGWK
IGFVCAAPQLLRVAAKVHQFLTFTTAPNLQTAVAYGLGKSDDYFINMRAELARSRDRLTAGLERLGFPVLKAQGTYFLTV
DLSPLGLNETDEQFCRRIVHDYKVAAIPVSAFYEKDAVTSVVRFCFAKKDATLDTALERLSDAIHRR
>Mature_387_residues
MISQNKVFADLPVTIFEQMSQLARDNNAINLGQGFPDDPGPEDIRRAAADAVLNGYNQYPSMMGLPELRQAIAAHYKHWH
KLDLDPMSEVMVTSGGTEALTSAILSVVEPGDEVICFQPVYDSYLPIIRQAGGIPKLLRLEPPHWRLSEEMLRSAFSAKT
KAVLFNNPLNPAAVVYPREDLELLARFCQDFDAVAICDEVWEHVVFDGREHIPLITIPGMRDRTIKVGSAGKIFSLTGWK
IGFVCAAPQLLRVAAKVHQFLTFTTAPNLQTAVAYGLGKSDDYFINMRAELARSRDRLTAGLERLGFPVLKAQGTYFLTV
DLSPLGLNETDEQFCRRIVHDYKVAAIPVSAFYEKDAVTSVVRFCFAKKDATLDTALERLSDAIHRR

Specific function: Shows aminotransferase activity with methionine and histidine as substrates, and to a lesser extent also with phenylalanine [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=397, Percent_Identity=37.0277078085642, Blast_Score=253, Evalue=3e-67,
Organism=Homo sapiens, GI56713256, Length=397, Percent_Identity=37.0277078085642, Blast_Score=252, Evalue=5e-67,
Organism=Homo sapiens, GI95147551, Length=396, Percent_Identity=35.3535353535354, Blast_Score=251, Evalue=1e-66,
Organism=Homo sapiens, GI169881279, Length=396, Percent_Identity=35.3535353535354, Blast_Score=251, Evalue=1e-66,
Organism=Homo sapiens, GI169881281, Length=393, Percent_Identity=31.0432569974555, Blast_Score=195, Evalue=5e-50,
Organism=Homo sapiens, GI4507369, Length=349, Percent_Identity=22.9226361031519, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1786816, Length=380, Percent_Identity=39.2105263157895, Blast_Score=271, Evalue=7e-74,
Organism=Escherichia coli, GI1788722, Length=366, Percent_Identity=24.0437158469945, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1788627, Length=310, Percent_Identity=21.9354838709677, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71994472, Length=400, Percent_Identity=34.25, Blast_Score=222, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI71994476, Length=400, Percent_Identity=34.25, Blast_Score=222, Evalue=3e-58,
Organism=Caenorhabditis elegans, GI17567369, Length=398, Percent_Identity=29.1457286432161, Blast_Score=195, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI17567663, Length=306, Percent_Identity=22.5490196078431, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6322401, Length=383, Percent_Identity=33.6814621409922, Blast_Score=194, Evalue=3e-50,
Organism=Drosophila melanogaster, GI28573069, Length=399, Percent_Identity=36.8421052631579, Blast_Score=253, Evalue=1e-67,
Organism=Drosophila melanogaster, GI24646114, Length=399, Percent_Identity=36.8421052631579, Blast_Score=253, Evalue=1e-67,
Organism=Drosophila melanogaster, GI28573067, Length=399, Percent_Identity=36.8421052631579, Blast_Score=253, Evalue=1e-67,
Organism=Drosophila melanogaster, GI28573065, Length=399, Percent_Identity=36.8421052631579, Blast_Score=253, Evalue=1e-67,
Organism=Drosophila melanogaster, GI18859735, Length=348, Percent_Identity=25, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 43114; Mature: 43114

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISQNKVFADLPVTIFEQMSQLARDNNAINLGQGFPDDPGPEDIRRAAADAVLNGYNQYP
CCCCCCEEECCCHHHHHHHHHHHHCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
SMMGLPELRQAIAAHYKHWHKLDLDPMSEVMVTSGGTEALTSAILSVVEPGDEVICFQPV
CCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEEECCC
YDSYLPIIRQAGGIPKLLRLEPPHWRLSEEMLRSAFSAKTKAVLFNNPLNPAAVVYPRED
HHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCEEEECHHH
LELLARFCQDFDAVAICDEVWEHVVFDGREHIPLITIPGMRDRTIKVGSAGKIFSLTGWK
HHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCEEEECCCCCEEEECCCE
IGFVCAAPQLLRVAAKVHQFLTFTTAPNLQTAVAYGLGKSDDYFINMRAELARSRDRLTA
EEHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHH
GLERLGFPVLKAQGTYFLTVDLSPLGLNETDEQFCRRIVHDYKVAAIPVSAFYEKDAVTS
HHHHHCCCEEEECCCEEEEEECCCCCCCCCHHHHHHHHHHHCCEEEEEHHHHHHHHHHHH
VVRFCFAKKDATLDTALERLSDAIHRR
HHHHHHHCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MISQNKVFADLPVTIFEQMSQLARDNNAINLGQGFPDDPGPEDIRRAAADAVLNGYNQYP
CCCCCCEEECCCHHHHHHHHHHHHCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
SMMGLPELRQAIAAHYKHWHKLDLDPMSEVMVTSGGTEALTSAILSVVEPGDEVICFQPV
CCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEEECCC
YDSYLPIIRQAGGIPKLLRLEPPHWRLSEEMLRSAFSAKTKAVLFNNPLNPAAVVYPRED
HHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCEEEECHHH
LELLARFCQDFDAVAICDEVWEHVVFDGREHIPLITIPGMRDRTIKVGSAGKIFSLTGWK
HHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCEEEECCCCCEEEECCCE
IGFVCAAPQLLRVAAKVHQFLTFTTAPNLQTAVAYGLGKSDDYFINMRAELARSRDRLTA
EEHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHH
GLERLGFPVLKAQGTYFLTVDLSPLGLNETDEQFCRRIVHDYKVAAIPVSAFYEKDAVTS
HHHHHCCCEEEECCCEEEEEECCCCCCCCCHHHHHHHHHHHCCEEEEEHHHHHHHHHHHH
VVRFCFAKKDATLDTALERLSDAIHRR
HHHHHHHCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]