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The map label for this gene is fabF [H]

Identifier: 146341576

GI number: 146341576

Start: 4865504

End: 4866709

Strand: Direct

Name: fabF [H]

Synonym: BRADO4677

Alternate gene names: 146341576

Gene position: 4865504-4866709 (Clockwise)

Preceding gene: 146341575

Following gene: 146341577

Centisome position: 65.25

GC content: 68.08

Gene sequence:

>1206_bases
ATGAGTGAGACGCCTTCCGTGACATCAGCCCCCGTCGAAGTCTGGATCACCGGCATCGGCCTTGCGACCTCGCTCGGCGA
GGGCCTCGATGCGAACTGGGAGGCTCTCAACGCCGGCCAGATCAATGTCGATGAGCAGGGCTTCGCGCCCTACATCGTGC
ATCCCTGGGCCAAGGTGAATCTCGAGGCGCAGATTCCGAAGAAGGAACAGCGCCAGATGGAGGCGTGGCAGCGCATCGGC
ACCTATGCCGCCGGGCTGGCGCTGGACTCGGCCGGGCTGAAGGGCAACAAGGACATCCTGTCCCGGATGGACATGATCGT
CGCCGCCGGCGGCGGCGAGCGCGACATCTCGGTCGACACCGCCATTCTCAACGCCGAGGCCGCGGGCAACTGCACGCCGG
GCTTCCTCAACGACCGGTTGATGAGCGATCTGCGGCCGACCCTGTTCCTGGCGCAGCTCTCGAATTTGCTCGCCGGCAAC
ATCGCGATCTCGCACGGCGTCTGCGGCACCTCGCGCACCTTCATGGGCGAAGAGGTCGCCGGCGTGGACGCGTTCAAGAT
CGCGCTTGCCCGCATCGCCGGCGGACAGAGCGACATCGCGCTGGTCGGCGGCTCGCACAATGGCGAGCGCAAGGACCTGC
TCGTGCTCTACGAGTTCGGCGACTACAATCTCAAGAACGAGTTCAAGCCGGTGTGGGCGCGCAAGGAGCATCCTGGCTTC
GCGCTCGGCTCGGCCGGCGCCTTCCTGGTGCTGGAGTCCAAGCCGCATGCCGAAGCCCGTGGCGCCAAGCCGCTGGCGCG
GCTGAGCAAGGTGGTGGCCGACCGCGCCCGCCGCAAGGAGGCCGGCGCCGTGACCGGTACGCTCGACCGGCTGTGGTCGG
CGCTGGACGTGCACGAGGCGCCGGGCGCGATCATCACCGGCGCCACCGGTGCCGAGCCCGTGACGTCGGAGGAGCGCGCA
TTCCTCGACCGCCACAAGGCGTTCGCCGTGCGCTCGAGCGGCACCCGCTTCGGCCACACGATGGAGGCGCATTTCGCGCT
CGATCTGGCGCTCGCCGCGCTGTCGATCTCGCGCGGCGCGCTGTTCGCGCCCGGCGACACCTCGGGAGTTGAGAGCGAGA
TGAATGAGGCTCCGGCCCAGATCGTGGTGGTCGGTGCTGGCCATTACCGCGGCGAAGGCATGGCCTTGGTCGAAGCTGTC
AAGTGA

Upstream 100 bases:

>100_bases
CGATCACGTTCAGCCACGTCCCCTTCCCCAATCCGGAACTGCGCGGACACATGGATGCCGTCGCCGAGCGCGTCGGCTTT
CCGCACCAGATCCTGCAGCG

Downstream 100 bases:

>100_bases
ACGCGGCGCGCGGCTAGACGACGCGACGGGGGACATCATGAGTGTACGCGACAAGTTTGGACGCCCCGTCGTGGTCGTGA
CGGGCATGGGCATCGTCACC

Product: 3-oxoacyl-(acyl carrier protein) synthase II

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MSETPSVTSAPVEVWITGIGLATSLGEGLDANWEALNAGQINVDEQGFAPYIVHPWAKVNLEAQIPKKEQRQMEAWQRIG
TYAAGLALDSAGLKGNKDILSRMDMIVAAGGGERDISVDTAILNAEAAGNCTPGFLNDRLMSDLRPTLFLAQLSNLLAGN
IAISHGVCGTSRTFMGEEVAGVDAFKIALARIAGGQSDIALVGGSHNGERKDLLVLYEFGDYNLKNEFKPVWARKEHPGF
ALGSAGAFLVLESKPHAEARGAKPLARLSKVVADRARRKEAGAVTGTLDRLWSALDVHEAPGAIITGATGAEPVTSEERA
FLDRHKAFAVRSSGTRFGHTMEAHFALDLALAALSISRGALFAPGDTSGVESEMNEAPAQIVVVGAGHYRGEGMALVEAV
K

Sequences:

>Translated_401_residues
MSETPSVTSAPVEVWITGIGLATSLGEGLDANWEALNAGQINVDEQGFAPYIVHPWAKVNLEAQIPKKEQRQMEAWQRIG
TYAAGLALDSAGLKGNKDILSRMDMIVAAGGGERDISVDTAILNAEAAGNCTPGFLNDRLMSDLRPTLFLAQLSNLLAGN
IAISHGVCGTSRTFMGEEVAGVDAFKIALARIAGGQSDIALVGGSHNGERKDLLVLYEFGDYNLKNEFKPVWARKEHPGF
ALGSAGAFLVLESKPHAEARGAKPLARLSKVVADRARRKEAGAVTGTLDRLWSALDVHEAPGAIITGATGAEPVTSEERA
FLDRHKAFAVRSSGTRFGHTMEAHFALDLALAALSISRGALFAPGDTSGVESEMNEAPAQIVVVGAGHYRGEGMALVEAV
K
>Mature_400_residues
SETPSVTSAPVEVWITGIGLATSLGEGLDANWEALNAGQINVDEQGFAPYIVHPWAKVNLEAQIPKKEQRQMEAWQRIGT
YAAGLALDSAGLKGNKDILSRMDMIVAAGGGERDISVDTAILNAEAAGNCTPGFLNDRLMSDLRPTLFLAQLSNLLAGNI
AISHGVCGTSRTFMGEEVAGVDAFKIALARIAGGQSDIALVGGSHNGERKDLLVLYEFGDYNLKNEFKPVWARKEHPGFA
LGSAGAFLVLESKPHAEARGAKPLARLSKVVADRARRKEAGAVTGTLDRLWSALDVHEAPGAIITGATGAEPVTSEERAF
LDRHKAFAVRSSGTRFGHTMEAHFALDLALAALSISRGALFAPGDTSGVESEMNEAPAQIVVVGAGHYRGEGMALVEAVK

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates and may function to supply the octanoic substrates for lipoic acid biosynthes

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Escherichia coli, GI1787337, Length=267, Percent_Identity=27.3408239700375, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 42320; Mature: 42189

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSETPSVTSAPVEVWITGIGLATSLGEGLDANWEALNAGQINVDEQGFAPYIVHPWAKVN
CCCCCCCCCCCEEEEEEECHHHHHHCCCCCCCCCEECCCEECCCCCCCCCEEECCCEEEE
LEAQIPKKEQRQMEAWQRIGTYAAGLALDSAGLKGNKDILSRMDMIVAAGGGERDISVDT
EEEECCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHEEEECCCCCCCCEEEE
AILNAEAAGNCTPGFLNDRLMSDLRPTLFLAQLSNLLAGNIAISHGVCGTSRTFMGEEVA
EEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCHHC
GVDAFKIALARIAGGQSDIALVGGSHNGERKDLLVLYEFGDYNLKNEFKPVWARKEHPGF
CCHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCE
ALGSAGAFLVLESKPHAEARGAKPLARLSKVVADRARRKEAGAVTGTLDRLWSALDVHEA
EECCCCEEEEEECCCCCHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
PGAIITGATGAEPVTSEERAFLDRHKAFAVRSSGTRFGHTMEAHFALDLALAALSISRGA
CCCEEECCCCCCCCCCHHHHHHHHHHHEEEECCCCCCCCEEHHHHHHHHHHHHHHHCCCE
LFAPGDTSGVESEMNEAPAQIVVVGAGHYRGEGMALVEAVK
EECCCCCCCCHHHHHCCCEEEEEEECCCCCCCCEEEEEECC
>Mature Secondary Structure 
SETPSVTSAPVEVWITGIGLATSLGEGLDANWEALNAGQINVDEQGFAPYIVHPWAKVN
CCCCCCCCCCEEEEEEECHHHHHHCCCCCCCCCEECCCEECCCCCCCCCEEECCCEEEE
LEAQIPKKEQRQMEAWQRIGTYAAGLALDSAGLKGNKDILSRMDMIVAAGGGERDISVDT
EEEECCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHEEEECCCCCCCCEEEE
AILNAEAAGNCTPGFLNDRLMSDLRPTLFLAQLSNLLAGNIAISHGVCGTSRTFMGEEVA
EEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCHHC
GVDAFKIALARIAGGQSDIALVGGSHNGERKDLLVLYEFGDYNLKNEFKPVWARKEHPGF
CCHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCE
ALGSAGAFLVLESKPHAEARGAKPLARLSKVVADRARRKEAGAVTGTLDRLWSALDVHEA
EECCCCEEEEEECCCCCHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
PGAIITGATGAEPVTSEERAFLDRHKAFAVRSSGTRFGHTMEAHFALDLALAALSISRGA
CCCEEECCCCCCCCCCHHHHHHHHHHHEEEECCCCCCCCEEHHHHHHHHHHHHHHHCCCE
LFAPGDTSGVESEMNEAPAQIVVVGAGHYRGEGMALVEAVK
EECCCCCCCCHHHHHCCCEEEEEEECCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]