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The map label for this gene is aes [C]

Identifier: 146341535

GI number: 146341535

Start: 4823707

End: 4824693

Strand: Direct

Name: aes [C]

Synonym: BRADO4633

Alternate gene names: 146341535

Gene position: 4823707-4824693 (Clockwise)

Preceding gene: 146341533

Following gene: 146341539

Centisome position: 64.69

GC content: 66.26

Gene sequence:

>987_bases
ATGTCCTCTGGCGAATCGATGCTGATCGGAGCTGTTCGAATGACGCTGACACGACTGGGCCTGACGCTCCTCGCGAGCGC
GTTGACGCTGAGCGCCGCGCAGGCGCAGCAGAGCCCGATGCCGGACGACATCGCCTGGAAGCTGATCGAGATCGGCCGGA
CGATCGACCCGCCGAAGACCTCTGCAATCTACGCGCCCTTGCAAGCCAAGGAACCCTACGCCGGCGTGAAGGTGCAGCGC
GATGTCCGATACGGCGCGGCCGAGCGCAACCTGCTCGATGTCTTCCTGCCTGACACGGCGGCCGCGCCGCGTCCGATCCT
GATGTTCGTGCATGGCGGCGCGTTCATCGGCGGCAACAAGCGCACCACGCCGGACAGCCCCTTCTACGACAACATCATGG
TTTGGGCGGCGAAAAGCGGCTTCGTCGGGATCAACATCACCTATCGCCTGGCGCCGAAATTCCCCTGGCCCGCCGGCGTG
GAGGATGTCGCCAGCGCCGTGCAATGGGTGGCGGCGCATGCCGCCGAGAACGGCGGCGATCCCGCGCGCATCTACCTGAT
GGGGCATTCGGCCGGCGCAGTGCATGTCGCGACTTACGTTGCGCATCCCGAATTCCACAAGGTCGGCGGCGGGGGCCTGG
CCGGAGCCATCATGGCATCGGGCATCTACGACCTCACCGCGTCGCCGCTCGGCGACCAGGAGATGGCCTATTTCGGCATT
GATCCCTCGCGCTTCAAGGAACGCTCGTCGCTCGAGGGCCTGCAGGCCTCGACCCTGCCGCTGATGATCGCCTCCGCCGA
GCTCGACCCGCCGCGCTTCGTCGAGCAGTTCGACCTGCTGAAGCAGGCCGTCTGCAAACGGCCAACGGGCTGTGCCCGCG
CGGTCATGCTGCCGCAGCACAGCCACATGTCGGAGGTGTATTCGATCAACACCGCTGACGACCGGCTGACGCGCGAGATC
GCCGAGTTTGTGCAGGCGGGGAAGTAG

Upstream 100 bases:

>100_bases
TCGGATCGGCTCTGGGTGCGTTTGATACGGCGGCTCATGAACGGTGCGTATCCCAAAAGCCACTGCCAGTCACGGCGAAA
TCGCGATAAATGCCGCGAGC

Downstream 100 bases:

>100_bases
CAACGCGCTCTCTCGACCGTCATTGCGAGCGCAGCGAAGCAATCCAGGGCGGAACGAGGACTCTGGATTGCTTCGCTGCG
CTCGCAATGACGTGGTGAAG

Product: putative esterase/lipase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MSSGESMLIGAVRMTLTRLGLTLLASALTLSAAQAQQSPMPDDIAWKLIEIGRTIDPPKTSAIYAPLQAKEPYAGVKVQR
DVRYGAAERNLLDVFLPDTAAAPRPILMFVHGGAFIGGNKRTTPDSPFYDNIMVWAAKSGFVGINITYRLAPKFPWPAGV
EDVASAVQWVAAHAAENGGDPARIYLMGHSAGAVHVATYVAHPEFHKVGGGGLAGAIMASGIYDLTASPLGDQEMAYFGI
DPSRFKERSSLEGLQASTLPLMIASAELDPPRFVEQFDLLKQAVCKRPTGCARAVMLPQHSHMSEVYSINTADDRLTREI
AEFVQAGK

Sequences:

>Translated_328_residues
MSSGESMLIGAVRMTLTRLGLTLLASALTLSAAQAQQSPMPDDIAWKLIEIGRTIDPPKTSAIYAPLQAKEPYAGVKVQR
DVRYGAAERNLLDVFLPDTAAAPRPILMFVHGGAFIGGNKRTTPDSPFYDNIMVWAAKSGFVGINITYRLAPKFPWPAGV
EDVASAVQWVAAHAAENGGDPARIYLMGHSAGAVHVATYVAHPEFHKVGGGGLAGAIMASGIYDLTASPLGDQEMAYFGI
DPSRFKERSSLEGLQASTLPLMIASAELDPPRFVEQFDLLKQAVCKRPTGCARAVMLPQHSHMSEVYSINTADDRLTREI
AEFVQAGK
>Mature_327_residues
SSGESMLIGAVRMTLTRLGLTLLASALTLSAAQAQQSPMPDDIAWKLIEIGRTIDPPKTSAIYAPLQAKEPYAGVKVQRD
VRYGAAERNLLDVFLPDTAAAPRPILMFVHGGAFIGGNKRTTPDSPFYDNIMVWAAKSGFVGINITYRLAPKFPWPAGVE
DVASAVQWVAAHAAENGGDPARIYLMGHSAGAVHVATYVAHPEFHKVGGGGLAGAIMASGIYDLTASPLGDQEMAYFGID
PSRFKERSSLEGLQASTLPLMIASAELDPPRFVEQFDLLKQAVCKRPTGCARAVMLPQHSHMSEVYSINTADDRLTREIA
EFVQAGK

Specific function: Has An Esterase Activity. Triacetyl Glycerol (Triacetin) Is A Substrate Of The Enzyme. [C]

COG id: COG0657

COG function: function code I; Esterase/lipase

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-B carboxylesterase/lipase family [H]

Homologues:

Organism=Homo sapiens, GI192807282, Length=246, Percent_Identity=27.2357723577236, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI17737825, Length=138, Percent_Identity=31.8840579710145, Blast_Score=72, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002018
- InterPro:   IPR019826 [H]

Pfam domain/function: PF00135 COesterase [H]

EC number: =3.1.1.1 [H]

Molecular weight: Translated: 35182; Mature: 35051

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSGESMLIGAVRMTLTRLGLTLLASALTLSAAQAQQSPMPDDIAWKLIEIGRTIDPPKT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCC
SAIYAPLQAKEPYAGVKVQRDVRYGAAERNLLDVFLPDTAAAPRPILMFVHGGAFIGGNK
CEEECCCCCCCCCCCCEEEECCCCCCCCCCEEEEECCCCCCCCCCEEEEEECCEEECCCC
RTTPDSPFYDNIMVWAAKSGFVGINITYRLAPKFPWPAGVEDVASAVQWVAAHAAENGGD
CCCCCCCCCCCEEEEEECCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
PARIYLMGHSAGAVHVATYVAHPEFHKVGGGGLAGAIMASGIYDLTASPLGDQEMAYFGI
CEEEEEEECCCCCEEEEEEEECCCHHCCCCCCHHHHHHHCCHHCCCCCCCCCCCEEEECC
DPSRFKERSSLEGLQASTLPLMIASAELDPPRFVEQFDLLKQAVCKRPTGCARAVMLPQH
CHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCHHEEECCCC
SHMSEVYSINTADDRLTREIAEFVQAGK
CCHHHHEECCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SSGESMLIGAVRMTLTRLGLTLLASALTLSAAQAQQSPMPDDIAWKLIEIGRTIDPPKT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCC
SAIYAPLQAKEPYAGVKVQRDVRYGAAERNLLDVFLPDTAAAPRPILMFVHGGAFIGGNK
CEEECCCCCCCCCCCCEEEECCCCCCCCCCEEEEECCCCCCCCCCEEEEEECCEEECCCC
RTTPDSPFYDNIMVWAAKSGFVGINITYRLAPKFPWPAGVEDVASAVQWVAAHAAENGGD
CCCCCCCCCCCEEEEEECCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
PARIYLMGHSAGAVHVATYVAHPEFHKVGGGGLAGAIMASGIYDLTASPLGDQEMAYFGI
CEEEEEEECCCCCEEEEEEEECCCHHCCCCCCHHHHHHHCCHHCCCCCCCCCCCEEEECC
DPSRFKERSSLEGLQASTLPLMIASAELDPPRFVEQFDLLKQAVCKRPTGCARAVMLPQH
CHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCHHEEECCCC
SHMSEVYSINTADDRLTREIAEFVQAGK
CCHHHHEECCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA