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The map label for this gene is era [H]

Identifier: 146341376

GI number: 146341376

Start: 4662752

End: 4663675

Strand: Reverse

Name: era [H]

Synonym: BRADO4462

Alternate gene names: 146341376

Gene position: 4663675-4662752 (Counterclockwise)

Preceding gene: 146341377

Following gene: 146341375

Centisome position: 62.54

GC content: 64.5

Gene sequence:

>924_bases
ATGACGGCTGAGCAACAGGCCGGGCAGGGCGCGACCCGCTGCGGTTTCGTCGCGCTGATCGGCGCTCCGAATGTCGGCAA
GTCGACCCTCGTCAATGCGCTGGTCGGCTCCAAGGTCACGATCGTCTCGCGCAAGGTGCAGACGACGCGCGCGCTGATCC
GCGGCATCGTCATCGAAGGTCAATCGCAGATCATCCTGGTCGACACGCCCGGCATCTTCTCGCCGAAGCGAAGGCTCGAC
CGCGCGATGGTCACGACGGCCTGGAGCGGCGCGCATGACGCCGATCTGGTCTGCGTGCTGCTCGATGCCAAGAAGGGCCT
GGACGACGAGGCGCAGGCCATCATCGACAAGGCGGCTTCGGTGGCGCACGAGAAGATACTGGTCGTCAACAAGGTCGACC
TGGTGCCGCGGGAAAAGCTGCTGGCTTTGGTCGCCGCGGCCAATGAGAAGCTGGCCTTCGCGCGCACCTTCATGATCTCG
GCGCTGTCGGGGGACGGCGTCGACGATCTCCGGCGCGCGCTGGCCGAGATGGTGCCGCCGGGACCGTTCCATTACCCCGA
AGACCAGATGTCGGACGCGCCGATGCGTCACCTCGCGGCCGAGATCACCCGCGAGAAGATCTATTCGCACCTGCATCAGG
AATTGCCCTATCAGTCCACGGTCGAGACCGACAGCTGGACCGAGCGCAACGACGGTTCGATCCGGATCGAGCAGACAATC
TTCGTGGAGCGTGACAGCCAGCGCAAGATCGTGCTCGGCAAGGGCGGCGCGACGATCAAGTCGATCGGGGCGCAGTCGCG
CAAGGAGATCGCCGAGATCACCGGCGTGCCGGTGCATCTGTTCCTGTTCGTGAAGGTGCGTGAGAACTGGGGCGACGATC
CCGACCGCTATCGAGAGATGGGTCTCGAGTTCCCTAGAGAATGA

Upstream 100 bases:

>100_bases
GGTCTGGAGCCGGCCGAAGGGGTGGGCGGATCCAAGCGGGCAGCCGAGAAGGTGGCGGCATCCGTGATGATCGAGCGCGA
GGGCGTGAGCGGCGGCAGCA

Downstream 100 bases:

>100_bases
CGATGAGCGTGCCGCGCAACGTGTTGTGGTTCGAAGTGCTGCTCTACAGCTCGCTGATGCTGGATGCGCTCTCGGTTGCC
GTCTCGGATCGCACGCCGAC

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MTAEQQAGQGATRCGFVALIGAPNVGKSTLVNALVGSKVTIVSRKVQTTRALIRGIVIEGQSQIILVDTPGIFSPKRRLD
RAMVTTAWSGAHDADLVCVLLDAKKGLDDEAQAIIDKAASVAHEKILVVNKVDLVPREKLLALVAAANEKLAFARTFMIS
ALSGDGVDDLRRALAEMVPPGPFHYPEDQMSDAPMRHLAAEITREKIYSHLHQELPYQSTVETDSWTERNDGSIRIEQTI
FVERDSQRKIVLGKGGATIKSIGAQSRKEIAEITGVPVHLFLFVKVRENWGDDPDRYREMGLEFPRE

Sequences:

>Translated_307_residues
MTAEQQAGQGATRCGFVALIGAPNVGKSTLVNALVGSKVTIVSRKVQTTRALIRGIVIEGQSQIILVDTPGIFSPKRRLD
RAMVTTAWSGAHDADLVCVLLDAKKGLDDEAQAIIDKAASVAHEKILVVNKVDLVPREKLLALVAAANEKLAFARTFMIS
ALSGDGVDDLRRALAEMVPPGPFHYPEDQMSDAPMRHLAAEITREKIYSHLHQELPYQSTVETDSWTERNDGSIRIEQTI
FVERDSQRKIVLGKGGATIKSIGAQSRKEIAEITGVPVHLFLFVKVRENWGDDPDRYREMGLEFPRE
>Mature_306_residues
TAEQQAGQGATRCGFVALIGAPNVGKSTLVNALVGSKVTIVSRKVQTTRALIRGIVIEGQSQIILVDTPGIFSPKRRLDR
AMVTTAWSGAHDADLVCVLLDAKKGLDDEAQAIIDKAASVAHEKILVVNKVDLVPREKLLALVAAANEKLAFARTFMISA
LSGDGVDDLRRALAEMVPPGPFHYPEDQMSDAPMRHLAAEITREKIYSHLHQELPYQSTVETDSWTERNDGSIRIEQTIF
VERDSQRKIVLGKGGATIKSIGAQSRKEIAEITGVPVHLFLFVKVRENWGDDPDRYREMGLEFPRE

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=322, Percent_Identity=31.6770186335404, Blast_Score=135, Evalue=5e-32,
Organism=Escherichia coli, GI1788919, Length=292, Percent_Identity=40.4109589041096, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI87082120, Length=166, Percent_Identity=29.5180722891566, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17532761, Length=154, Percent_Identity=34.4155844155844, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24646434, Length=308, Percent_Identity=25.974025974026, Blast_Score=105, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 33717; Mature: 33586

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAEQQAGQGATRCGFVALIGAPNVGKSTLVNALVGSKVTIVSRKVQTTRALIRGIVIEG
CCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHEEEC
QSQIILVDTPGIFSPKRRLDRAMVTTAWSGAHDADLVCVLLDAKKGLDDEAQAIIDKAAS
CCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHH
VAHEKILVVNKVDLVPREKLLALVAAANEKLAFARTFMISALSGDGVDDLRRALAEMVPP
HHHHEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
GPFHYPEDQMSDAPMRHLAAEITREKIYSHLHQELPYQSTVETDSWTERNDGSIRIEQTI
CCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEE
FVERDSQRKIVLGKGGATIKSIGAQSRKEIAEITGVPVHLFLFVKVRENWGDDPDRYREM
EEEECCCCEEEEECCCCHHHHHCCHHHHHHHHHCCCCEEEEEEEEEECCCCCCHHHHHHH
GLEFPRE
CCCCCCC
>Mature Secondary Structure 
TAEQQAGQGATRCGFVALIGAPNVGKSTLVNALVGSKVTIVSRKVQTTRALIRGIVIEG
CCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHEEEC
QSQIILVDTPGIFSPKRRLDRAMVTTAWSGAHDADLVCVLLDAKKGLDDEAQAIIDKAAS
CCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHH
VAHEKILVVNKVDLVPREKLLALVAAANEKLAFARTFMISALSGDGVDDLRRALAEMVPP
HHHHEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
GPFHYPEDQMSDAPMRHLAAEITREKIYSHLHQELPYQSTVETDSWTERNDGSIRIEQTI
CCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEE
FVERDSQRKIVLGKGGATIKSIGAQSRKEIAEITGVPVHLFLFVKVRENWGDDPDRYREM
EEEECCCCEEEEECCCCHHHHHCCHHHHHHHHHCCCCEEEEEEEEEECCCCCCHHHHHHH
GLEFPRE
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA