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The map label for this gene is ribC [H]

Identifier: 146341343

GI number: 146341343

Start: 4630845

End: 4631453

Strand: Reverse

Name: ribC [H]

Synonym: BRADO4427

Alternate gene names: 146341343

Gene position: 4631453-4630845 (Counterclockwise)

Preceding gene: 146341344

Following gene: 146341342

Centisome position: 62.11

GC content: 63.88

Gene sequence:

>609_bases
ATGTTTACCGGCATCGTCACCGACATCGGCGAGATCGTCAGCCTGACGCCGCGGACCGAGGGCAAGCTGCACCGGCTGCG
CATCGCCAGCGCTTACGACCAGTCCACGATCGCCGATGGCGCGTCGATCGCCAACAATGGCGTCTGCCTCACGGTTGTGC
AGTCCGGTATTGCCGACGGAAAGACCTGGTTCGAGGTCGATGCCGCCGCGGAGACTCTGGCGCTGACGACCGCCAAGCAT
TGGCGCGTCGGCACCAAGCTGAATCTGGAGCGCGCGCTGAAGATCGGCGACGAGCTCGGCGGCCATATCGTCTCCGGCCA
TGTCGACGGCATCGCCACCATCGTCAGCCGCGAGAACCTGCCGGATATGGCGCGGTTCGTGTTCAGGACAACGCGCGAGC
TGGCCCGCTTCATCGCCACCAAGGGTTCGATCACCCTCGATGGCGTGTCGCTCACGGTCAACACCGTGGACGAACTCACC
TTCTCGGTGCTGATCATTCCGCATACCCTGGCGGTCACCACGCTGTCATCCTGGCAGACGGGCAGCGAGGTCAATATCGA
GGTCGACCTGATGGCGCGCTATGCGGCGCGCCTCACGGAAATGAAGTAG

Upstream 100 bases:

>100_bases
ACGCATTGCCGCTGACCGCAATCACGCAGTCGCCCGCTTATCGCGTTCGTGCTAGCGAAACGCTCGATCCCGACATCCTT
ACGATTTACGAGCGCGTGTA

Downstream 100 bases:

>100_bases
CTTGGAATCGAAGACGCTGGCGCCTAAAACGCCGGCCCATCTCCTCATGGTGAGGAGGCGCATGCACCGGAGCAGGCCGA
GCACTCGCGAGGCCGGACGA

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MFTGIVTDIGEIVSLTPRTEGKLHRLRIASAYDQSTIADGASIANNGVCLTVVQSGIADGKTWFEVDAAAETLALTTAKH
WRVGTKLNLERALKIGDELGGHIVSGHVDGIATIVSRENLPDMARFVFRTTRELARFIATKGSITLDGVSLTVNTVDELT
FSVLIIPHTLAVTTLSSWQTGSEVNIEVDLMARYAARLTEMK

Sequences:

>Translated_202_residues
MFTGIVTDIGEIVSLTPRTEGKLHRLRIASAYDQSTIADGASIANNGVCLTVVQSGIADGKTWFEVDAAAETLALTTAKH
WRVGTKLNLERALKIGDELGGHIVSGHVDGIATIVSRENLPDMARFVFRTTRELARFIATKGSITLDGVSLTVNTVDELT
FSVLIIPHTLAVTTLSSWQTGSEVNIEVDLMARYAARLTEMK
>Mature_202_residues
MFTGIVTDIGEIVSLTPRTEGKLHRLRIASAYDQSTIADGASIANNGVCLTVVQSGIADGKTWFEVDAAAETLALTTAKH
WRVGTKLNLERALKIGDELGGHIVSGHVDGIATIVSRENLPDMARFVFRTTRELARFIATKGSITLDGVSLTVNTVDELT
FSVLIIPHTLAVTTLSSWQTGSEVNIEVDLMARYAARLTEMK

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=193, Percent_Identity=37.8238341968912, Blast_Score=108, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6319733, Length=203, Percent_Identity=37.4384236453202, Blast_Score=108, Evalue=7e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 21798; Mature: 21798

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS00693 LUM_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGIVTDIGEIVSLTPRTEGKLHRLRIASAYDQSTIADGASIANNGVCLTVVQSGIADG
CCCCHHHHHHHHHCCCCCCCCCEEEEEEECCCCCHHHCCCCCCCCCCEEEEEECCCCCCC
KTWFEVDAAAETLALTTAKHWRVGTKLNLERALKIGDELGGHIVSGHVDGIATIVSRENL
CEEEEEHHHHHHHHEECHHHEECCCEECHHHHHHHHHHHCCEEEECCCCHHHHHHCCCCC
PDMARFVFRTTRELARFIATKGSITLDGVSLTVNTVDELTFSVLIIPHTLAVTTLSSWQT
HHHHHHHHHHHHHHHHHHHCCCCEEECCEEEEEEEHHHHEEEEEEECCHHEEEEECCCCC
GSEVNIEVDLMARYAARLTEMK
CCEEEEEHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFTGIVTDIGEIVSLTPRTEGKLHRLRIASAYDQSTIADGASIANNGVCLTVVQSGIADG
CCCCHHHHHHHHHCCCCCCCCCEEEEEEECCCCCHHHCCCCCCCCCCEEEEEECCCCCCC
KTWFEVDAAAETLALTTAKHWRVGTKLNLERALKIGDELGGHIVSGHVDGIATIVSRENL
CEEEEEHHHHHHHHEECHHHEECCCEECHHHHHHHHHHHCCEEEECCCCHHHHHHCCCCC
PDMARFVFRTTRELARFIATKGSITLDGVSLTVNTVDELTFSVLIIPHTLAVTTLSSWQT
HHHHHHHHHHHHHHHHHHHCCCCEEECCEEEEEEEHHHHEEEEEEECCHHEEEEECCCCC
GSEVNIEVDLMARYAARLTEMK
CCEEEEEHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8144477 [H]