Click here to switch to the map view.

The map label for this gene is thiL [H]

Identifier: 146341340

GI number: 146341340

Start: 4627995

End: 4628987

Strand: Reverse

Name: thiL [H]

Synonym: BRADO4424

Alternate gene names: 146341340

Gene position: 4628987-4627995 (Counterclockwise)

Preceding gene: 146341341

Following gene: 146341339

Centisome position: 62.08

GC content: 66.77

Gene sequence:

>993_bases
ATGACCCAGGCTCCCTCCGGCGAAGATTCCCTCATCGCCCGCTACTTCAAGCCGTTGGCGACCGATCCCGGCGCTTTCGG
CCTCGTCGATGATGCCGCCGCCATCCCGGCCGGCGGTGACGACCTCGTCGTCAACACCGACGCTATCGTCGAAGGCGTCC
ATTATCTGCCTGACGATCCGCCCGACACGATCGCGCGCAAGGCACTGCGGGTGAACCTGTCCGATCTCGCCGCCAAGGGC
GCGGTGCCGGCCGGCTTCCTGCTGACGCTCGCACTGCGTCAGAAGGACGAGACCTGGCTCGCCGCTTTCGCTGGCGGTCT
TGGCGAGGACGCAGCGACCTTCGGCTGCCCGCTGCTCGGCGGTGACACCGTGTCAACGCCGGGCCCCGTCATGATATCCG
TCACCGCCTGGGGGCGTGTTCCCAGAGGCCGCATGGTGCACCGCTTCGGCGCTCGACCCGGCGACCGGGTGATGGTCACT
GGCACGATCGGTGATGCCGCGCTCGGCCTGCGCGTTCTTCAGGGCAGAGCAGAGGCGGGCGTACTGGACGCCGATGCCGC
CGCGCGGGAAATGCTGATCGGCCGCTATCGTGTGCCGCAACCGCGCAGCGCGCTGGCAACCGCCGTGCGGGACTACGCGA
CGGCATCGATGGACGTCTCCGATGGACTTGCCGGCGACCTGACCAAGCTTTGTGCTGCCTCTTCCGCGAGCGCCGACATT
GCTCTGTCATACGTTCCGATCTCATCAGCAGCTGCCAAGCTGATTGCCGAAGGCGTGGTGCAACTGGAAACTTTGATCTC
CGGCGGCGACGACTACGAGATCCTCTGCACCGTTCCCGCAGCGCAATGCGAAGCATTTCGCACTGCGGCTGTCGCTGCCG
GCATCGCCGTCACCGACATCGGCGCGATCGTCGAGGGCACGCAGGCGCCGCGCTTCCTTGACGGCCAGGGCCGTCCAGTC
CGCTTGAAACGGCTGTCCTACAGCCACTTCTGA

Upstream 100 bases:

>100_bases
TCCAGTATTCCAGAAACGTCAGTGGGATACGGAGGGGCCGCGGCGTACTGGATCGCCCGGTCAAGCCGGGCGATGACGGC
GGAGAGTGGGGAGGGCACGC

Downstream 100 bases:

>100_bases
GACCCATTCGCAGCCGCACAATGCGACCAAAGAAGCGTCTGAATTTGGAGCGGTTCAGGTGTCGCGGCGTTGCGTCAACA
TGGCGATTTTGGCAAGGTCC

Product: thiamin-monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MTQAPSGEDSLIARYFKPLATDPGAFGLVDDAAAIPAGGDDLVVNTDAIVEGVHYLPDDPPDTIARKALRVNLSDLAAKG
AVPAGFLLTLALRQKDETWLAAFAGGLGEDAATFGCPLLGGDTVSTPGPVMISVTAWGRVPRGRMVHRFGARPGDRVMVT
GTIGDAALGLRVLQGRAEAGVLDADAAAREMLIGRYRVPQPRSALATAVRDYATASMDVSDGLAGDLTKLCAASSASADI
ALSYVPISSAAAKLIAEGVVQLETLISGGDDYEILCTVPAAQCEAFRTAAVAAGIAVTDIGAIVEGTQAPRFLDGQGRPV
RLKRLSYSHF

Sequences:

>Translated_330_residues
MTQAPSGEDSLIARYFKPLATDPGAFGLVDDAAAIPAGGDDLVVNTDAIVEGVHYLPDDPPDTIARKALRVNLSDLAAKG
AVPAGFLLTLALRQKDETWLAAFAGGLGEDAATFGCPLLGGDTVSTPGPVMISVTAWGRVPRGRMVHRFGARPGDRVMVT
GTIGDAALGLRVLQGRAEAGVLDADAAAREMLIGRYRVPQPRSALATAVRDYATASMDVSDGLAGDLTKLCAASSASADI
ALSYVPISSAAAKLIAEGVVQLETLISGGDDYEILCTVPAAQCEAFRTAAVAAGIAVTDIGAIVEGTQAPRFLDGQGRPV
RLKRLSYSHF
>Mature_329_residues
TQAPSGEDSLIARYFKPLATDPGAFGLVDDAAAIPAGGDDLVVNTDAIVEGVHYLPDDPPDTIARKALRVNLSDLAAKGA
VPAGFLLTLALRQKDETWLAAFAGGLGEDAATFGCPLLGGDTVSTPGPVMISVTAWGRVPRGRMVHRFGARPGDRVMVTG
TIGDAALGLRVLQGRAEAGVLDADAAAREMLIGRYRVPQPRSALATAVRDYATASMDVSDGLAGDLTKLCAASSASADIA
LSYVPISSAAAKLIAEGVVQLETLISGGDDYEILCTVPAAQCEAFRTAAVAAGIAVTDIGAIVEGTQAPRFLDGQGRPVR
LKRLSYSHF

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=328, Percent_Identity=40.8536585365854, Blast_Score=192, Evalue=2e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 34016; Mature: 33885

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQAPSGEDSLIARYFKPLATDPGAFGLVDDAAAIPAGGDDLVVNTDAIVEGVHYLPDDP
CCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCC
PDTIARKALRVNLSDLAAKGAVPAGFLLTLALRQKDETWLAAFAGGLGEDAATFGCPLLG
HHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHCCCCCC
GDTVSTPGPVMISVTAWGRVPRGRMVHRFGARPGDRVMVTGTIGDAALGLRVLQGRAEAG
CCCCCCCCCEEEEEEECCCCCCCHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHCCCCCC
VLDADAAAREMLIGRYRVPQPRSALATAVRDYATASMDVSDGLAGDLTKLCAASSASADI
CCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCE
ALSYVPISSAAAKLIAEGVVQLETLISGGDDYEILCTVPAAQCEAFRTAAVAAGIAVTDI
EEEEEECHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHCHHHHHH
GAIVEGTQAPRFLDGQGRPVRLKRLSYSHF
HHHHCCCCCCCEECCCCCEEEEEECCCCCC
>Mature Secondary Structure 
TQAPSGEDSLIARYFKPLATDPGAFGLVDDAAAIPAGGDDLVVNTDAIVEGVHYLPDDP
CCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCC
PDTIARKALRVNLSDLAAKGAVPAGFLLTLALRQKDETWLAAFAGGLGEDAATFGCPLLG
HHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHCCCCCC
GDTVSTPGPVMISVTAWGRVPRGRMVHRFGARPGDRVMVTGTIGDAALGLRVLQGRAEAG
CCCCCCCCCEEEEEEECCCCCCCHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHCCCCCC
VLDADAAAREMLIGRYRVPQPRSALATAVRDYATASMDVSDGLAGDLTKLCAASSASADI
CCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCE
ALSYVPISSAAAKLIAEGVVQLETLISGGDDYEILCTVPAAQCEAFRTAAVAAGIAVTDI
EEEEEECHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHCHHHHHH
GAIVEGTQAPRFLDGQGRPVRLKRLSYSHF
HHHHCCCCCCCEECCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]