Click here to switch to the map view.

The map label for this gene is fabH [H]

Identifier: 146341333

GI number: 146341333

Start: 4619999

End: 4620973

Strand: Reverse

Name: fabH [H]

Synonym: BRADO4417

Alternate gene names: 146341333

Gene position: 4620973-4619999 (Counterclockwise)

Preceding gene: 146341334

Following gene: 146341332

Centisome position: 61.97

GC content: 66.87

Gene sequence:

>975_bases
GTGACAATTCGTTCGGTCGTGCTCGGCTGTGGCTCCTATCTTCCGCAGCGGGTCGTGACCAATGCCGAACTTGCAAGCCG
GATCGAAACCTCGGACGAGTGGATCGTCCAGCGCACCGGCATCCGGGAGCGCCATGTGGCGGCCGACGGCGAGTTCACCT
CCCACCTCGCGATCAATGCCGCCCGTGCGGCGCTCGCCAATGCGGATGTCGATCCGCAGTCGATCGACCTGATCGTGCTG
GGCACCTCGACGCCGGACAACACCTTTCCGGCCACGGCGGTCGCCGTGCAGAACGGCCTCGGAATTCATCACGGGGCGGC
GTTCGACCTGCAGGCCGTCTGCTCCGGCTTTGTCTACGCCTTGGCGACCGCCGACAATTTCCTGCGCAGCGGCTCGTTCA
AGCGGGCGCTGGTGATCGGCGCCGAGACCTTCTCGCGCATCCTCGACTGGAACGACCGCACCACCTGCGTGCTGTTCGGC
GACGGCGCCGGCGCGCTGGTGCTGGATGCCCAGCAGCAGGGCGGCACCGCGGCTGATCGCGGCGTGCTGAGCACGCATCT
GCGCTCGGACGGCCGCCACAAGGCCAAGCTCTACGTCGATGGCGGCCCGTCCTCGACCCAGACCGTCGGTCACCTCCGCA
TGGAGGGCCGCGAGGTCTTCAAGCACGCGGTCGGCATGATCACGGACGTCATCGTCGATGCCTTCGAGGCGACCGGGCTG
TCGGCCGAGACCATCGACTGGTTCGTGCCGCACCAGGCCAACAAGCGAATCATCGACGCCTCGGCGCACAAGCTGCATAT
CGCGCCGGAAAAGGTGGTGCTGACGGTCGATCGGCATGGAAATACCTCTGCCGCCTCGATCCCGCTGGCGCTCGACGTCG
CGGTCAAAGACGGCCGGATCAAGAAGGGCGATGTCGTTCTGCTGGAGGCGATGGGCGGCGGATTCACCTGGGGCTCGGCC
CTGGTGCGCTGGTGA

Upstream 100 bases:

>100_bases
ATGAGATGGCCCGCTGCGATCTCCTGACCAAGATCAATCAAACACTCAATCGCGACGGCGGCGCATCGGCGTCCGAACCG
GTCGCCCAGGAGGCTGTCTC

Downstream 100 bases:

>100_bases
GCCATTCCGTTGCACGAGATTTGGCTGGGACGAATGGTGCCCAGCCCGCCAGTTCGGTTCACGCTGCTGTTGACCATTGC
CGCTTAACCTCTTAATTTCC

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MTIRSVVLGCGSYLPQRVVTNAELASRIETSDEWIVQRTGIRERHVAADGEFTSHLAINAARAALANADVDPQSIDLIVL
GTSTPDNTFPATAVAVQNGLGIHHGAAFDLQAVCSGFVYALATADNFLRSGSFKRALVIGAETFSRILDWNDRTTCVLFG
DGAGALVLDAQQQGGTAADRGVLSTHLRSDGRHKAKLYVDGGPSSTQTVGHLRMEGREVFKHAVGMITDVIVDAFEATGL
SAETIDWFVPHQANKRIIDASAHKLHIAPEKVVLTVDRHGNTSAASIPLALDVAVKDGRIKKGDVVLLEAMGGGFTWGSA
LVRW

Sequences:

>Translated_324_residues
MTIRSVVLGCGSYLPQRVVTNAELASRIETSDEWIVQRTGIRERHVAADGEFTSHLAINAARAALANADVDPQSIDLIVL
GTSTPDNTFPATAVAVQNGLGIHHGAAFDLQAVCSGFVYALATADNFLRSGSFKRALVIGAETFSRILDWNDRTTCVLFG
DGAGALVLDAQQQGGTAADRGVLSTHLRSDGRHKAKLYVDGGPSSTQTVGHLRMEGREVFKHAVGMITDVIVDAFEATGL
SAETIDWFVPHQANKRIIDASAHKLHIAPEKVVLTVDRHGNTSAASIPLALDVAVKDGRIKKGDVVLLEAMGGGFTWGSA
LVRW
>Mature_323_residues
TIRSVVLGCGSYLPQRVVTNAELASRIETSDEWIVQRTGIRERHVAADGEFTSHLAINAARAALANADVDPQSIDLIVLG
TSTPDNTFPATAVAVQNGLGIHHGAAFDLQAVCSGFVYALATADNFLRSGSFKRALVIGAETFSRILDWNDRTTCVLFGD
GAGALVLDAQQQGGTAADRGVLSTHLRSDGRHKAKLYVDGGPSSTQTVGHLRMEGREVFKHAVGMITDVIVDAFEATGLS
AETIDWFVPHQANKRIIDASAHKLHIAPEKVVLTVDRHGNTSAASIPLALDVAVKDGRIKKGDVVLLEAMGGGFTWGSAL
VRW

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=319, Percent_Identity=49.2163009404389, Blast_Score=306, Evalue=1e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.41 [H]

Molecular weight: Translated: 34471; Mature: 34340

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIRSVVLGCGSYLPQRVVTNAELASRIETSDEWIVQRTGIRERHVAADGEFTSHLAINA
CCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCEEEECCCCCHHEECCCCCCHHHEEHHH
ARAALANADVDPQSIDLIVLGTSTPDNTFPATAVAVQNGLGIHHGAAFDLQAVCSGFVYA
HHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCEEHHCCCCCCCCCCCCHHHHHHHHHHH
LATADNFLRSGSFKRALVIGAETFSRILDWNDRTTCVLFGDGAGALVLDAQQQGGTAADR
HHHHHHHHHCCCCCEEEEEEHHHHHHHHCCCCCEEEEEEECCCCEEEEECHHCCCCHHHC
GVLSTHLRSDGRHKAKLYVDGGPSSTQTVGHLRMEGREVFKHAVGMITDVIVDAFEATGL
CHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SAETIDWFVPHQANKRIIDASAHKLHIAPEKVVLTVDRHGNTSAASIPLALDVAVKDGRI
CCCCEEEECCCCCCCEEEECCCCEEEECCCEEEEEEECCCCCCCEECEEEEEEEEECCCC
KKGDVVLLEAMGGGFTWGSALVRW
CCCCEEEEEECCCCEEHHHHHCCC
>Mature Secondary Structure 
TIRSVVLGCGSYLPQRVVTNAELASRIETSDEWIVQRTGIRERHVAADGEFTSHLAINA
CHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCEEEECCCCCHHEECCCCCCHHHEEHHH
ARAALANADVDPQSIDLIVLGTSTPDNTFPATAVAVQNGLGIHHGAAFDLQAVCSGFVYA
HHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCEEHHCCCCCCCCCCCCHHHHHHHHHHH
LATADNFLRSGSFKRALVIGAETFSRILDWNDRTTCVLFGDGAGALVLDAQQQGGTAADR
HHHHHHHHHCCCCCEEEEEEHHHHHHHHCCCCCEEEEEEECCCCEEEEECHHCCCCHHHC
GVLSTHLRSDGRHKAKLYVDGGPSSTQTVGHLRMEGREVFKHAVGMITDVIVDAFEATGL
CHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SAETIDWFVPHQANKRIIDASAHKLHIAPEKVVLTVDRHGNTSAASIPLALDVAVKDGRI
CCCCEEEECCCCCCCEEEECCCCEEEECCCEEEEEEECCCCCCCEECEEEEEEEEECCCC
KKGDVVLLEAMGGGFTWGSALVRW
CCCCEEEEEECCCCEEHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA