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The map label for this gene is tatA [H]

Identifier: 146340452

GI number: 146340452

Start: 3674875

End: 3676041

Strand: Reverse

Name: tatA [H]

Synonym: BRADO3492

Alternate gene names: 146340452

Gene position: 3676041-3674875 (Counterclockwise)

Preceding gene: 146340453

Following gene: 146340451

Centisome position: 49.3

GC content: 69.32

Gene sequence:

>1167_bases
ATGTTCGAACGCCTGAGCCGCCAGCCCGACGATCCCCTGCTCGCTTTGATCGGCATCTTCAAAGCCGATCCGCGGACCGA
CAAGGTCGATCTGGGCGTCGGGGTCTACCGCGACGAGGCCGGCCACTCGCCGATCTTTCGCGCGGTGAAGGCCGCCGAGC
AGCGGATCTGGGCGAGCCAGGACAGCAAGGCCTATGTCGCTCCGGAAGGCGACCAGGGCTTCCTGGACCTGCTGTGGACG
ATGGTCGGCGGCAAGGCCTCGCCGGTGCATGCCGCTGGCGTGCAGACCCCCGGCGGCTCCGGCGCGCTGCGGCTGGCCGC
CGACCTGATCCGCCAGGCGGGCACCGGCCGGATCTGGCTGGGCTTGCCGAGCTGGCCCAACCACGCCGGCATTTTTGCCG
CGGCCGGGCTCGCGATCGAGACCTATCCCTATTTCGACGTTCCGTCGCAGACCCTGCTGCTCGACGGCATGCTCGAGGCC
TTGCAGCGTGCCCAGCCGGGCGATGCCGTGCTGCTGCATGCGTCCTGCCACAATCCGACCGGCGCCCCATTGGGCGCCGC
GGACTGGGCGCGCATCACCGACGTGATCGCCACGCGTGGGCTGGTGCCGCTGATCGACTCCGCCTATCAGGGTTTTGGCG
CCGGATTTGAGGGCGACGTCGCCGGGCTGCGGGCGCTGGTCGCGGCGATCCCCGAGGCGCTCGTCGCGGTGTCCTGCTCG
AAGTCCTTCGGCCTTTATCGCGAGCGCACCGGCGCGCTGTTTGCCGTTGCGGGTACGACGGCCGCAGTGGAGACGGCGCG
CTCCAATCTCGTCGCCATCGCCCGCACCAGCTACTCGATGCCGCCGGACCATGGCTCGGCGATCGTCAAGACCATCCTCG
GCACACCTGAGCTCTACGACGACTGGCGCGCCGAGCTCGAGTCGATGCGCCAGCGCCTCGCCAGCTTGCGCCGCTCGTTC
GCCGAGGCGCTCGGCGGCCGCTGGTCGAACTCCCTGGCGATCGGCAAGCAGGAAGGCATGTTCTCGCTGCTGCCGCTGAC
GCCGGCCGAGGTGATGACCTTGCGAGAGAAGCACGGCGTGTACATGCCGACCTCGGGCCGCATCAACGTCGCCGGACTGA
AACTGTCGGACGTCACCCGCGTCGCCGGCCTGTTCAAGGCGATCTGA

Upstream 100 bases:

>100_bases
AATTCCCGCTGTTTTTGCGCCGCAACCCGGCTAGTGTCCGCGCGCCTGCCGGGCGGCCAAGGGCTGCCCGCGGTGCACGA
CGCAACAGGAATGCTCCCCG

Downstream 100 bases:

>100_bases
GCGCTGCAGGCAGGGCCGTCGTGACCGAGACTGTGCCGGAGCGTCACAAGCTCTACGAGGATGCGATGGCGCTGACGCTC
GGCACGCTGTTCGTGTCGCT

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: TAT; L-tyrosine:2-oxoglutarate aminotransferase [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MFERLSRQPDDPLLALIGIFKADPRTDKVDLGVGVYRDEAGHSPIFRAVKAAEQRIWASQDSKAYVAPEGDQGFLDLLWT
MVGGKASPVHAAGVQTPGGSGALRLAADLIRQAGTGRIWLGLPSWPNHAGIFAAAGLAIETYPYFDVPSQTLLLDGMLEA
LQRAQPGDAVLLHASCHNPTGAPLGAADWARITDVIATRGLVPLIDSAYQGFGAGFEGDVAGLRALVAAIPEALVAVSCS
KSFGLYRERTGALFAVAGTTAAVETARSNLVAIARTSYSMPPDHGSAIVKTILGTPELYDDWRAELESMRQRLASLRRSF
AEALGGRWSNSLAIGKQEGMFSLLPLTPAEVMTLREKHGVYMPTSGRINVAGLKLSDVTRVAGLFKAI

Sequences:

>Translated_388_residues
MFERLSRQPDDPLLALIGIFKADPRTDKVDLGVGVYRDEAGHSPIFRAVKAAEQRIWASQDSKAYVAPEGDQGFLDLLWT
MVGGKASPVHAAGVQTPGGSGALRLAADLIRQAGTGRIWLGLPSWPNHAGIFAAAGLAIETYPYFDVPSQTLLLDGMLEA
LQRAQPGDAVLLHASCHNPTGAPLGAADWARITDVIATRGLVPLIDSAYQGFGAGFEGDVAGLRALVAAIPEALVAVSCS
KSFGLYRERTGALFAVAGTTAAVETARSNLVAIARTSYSMPPDHGSAIVKTILGTPELYDDWRAELESMRQRLASLRRSF
AEALGGRWSNSLAIGKQEGMFSLLPLTPAEVMTLREKHGVYMPTSGRINVAGLKLSDVTRVAGLFKAI
>Mature_388_residues
MFERLSRQPDDPLLALIGIFKADPRTDKVDLGVGVYRDEAGHSPIFRAVKAAEQRIWASQDSKAYVAPEGDQGFLDLLWT
MVGGKASPVHAAGVQTPGGSGALRLAADLIRQAGTGRIWLGLPSWPNHAGIFAAAGLAIETYPYFDVPSQTLLLDGMLEA
LQRAQPGDAVLLHASCHNPTGAPLGAADWARITDVIATRGLVPLIDSAYQGFGAGFEGDVAGLRALVAAIPEALVAVSCS
KSFGLYRERTGALFAVAGTTAAVETARSNLVAIARTSYSMPPDHGSAIVKTILGTPELYDDWRAELESMRQRLASLRRSF
AEALGGRWSNSLAIGKQEGMFSLLPLTPAEVMTLREKHGVYMPTSGRINVAGLKLSDVTRVAGLFKAI

Specific function: Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate [H]

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4504067, Length=389, Percent_Identity=36.2467866323907, Blast_Score=220, Evalue=2e-57,
Organism=Homo sapiens, GI73486658, Length=383, Percent_Identity=33.1592689295039, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI117414139, Length=383, Percent_Identity=24.8041775456919, Blast_Score=117, Evalue=2e-26,
Organism=Escherichia coli, GI1787159, Length=380, Percent_Identity=42.8947368421053, Blast_Score=317, Evalue=1e-87,
Organism=Escherichia coli, GI1790488, Length=396, Percent_Identity=38.3838383838384, Blast_Score=265, Evalue=3e-72,
Organism=Caenorhabditis elegans, GI71981858, Length=389, Percent_Identity=32.9048843187661, Blast_Score=220, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI25147133, Length=384, Percent_Identity=33.8541666666667, Blast_Score=207, Evalue=8e-54,
Organism=Caenorhabditis elegans, GI17569539, Length=368, Percent_Identity=31.5217391304348, Blast_Score=183, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17569537, Length=375, Percent_Identity=25.3333333333333, Blast_Score=124, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI25147136, Length=203, Percent_Identity=33.0049261083744, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17550384, Length=273, Percent_Identity=27.8388278388278, Blast_Score=112, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6323055, Length=401, Percent_Identity=33.1670822942643, Blast_Score=213, Evalue=4e-56,
Organism=Saccharomyces cerevisiae, GI6322743, Length=427, Percent_Identity=29.5081967213115, Blast_Score=179, Evalue=7e-46,
Organism=Drosophila melanogaster, GI24654046, Length=400, Percent_Identity=35, Blast_Score=218, Evalue=6e-57,
Organism=Drosophila melanogaster, GI19922362, Length=400, Percent_Identity=35, Blast_Score=218, Evalue=6e-57,
Organism=Drosophila melanogaster, GI24580970, Length=390, Percent_Identity=32.0512820512821, Blast_Score=202, Evalue=5e-52,
Organism=Drosophila melanogaster, GI24580972, Length=390, Percent_Identity=32.0512820512821, Blast_Score=201, Evalue=6e-52,
Organism=Drosophila melanogaster, GI19920542, Length=383, Percent_Identity=32.3759791122715, Blast_Score=200, Evalue=1e-51,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.5 [H]

Molecular weight: Translated: 41203; Mature: 41203

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFERLSRQPDDPLLALIGIFKADPRTDKVDLGVGVYRDEAGHSPIFRAVKAAEQRIWASQ
CCCCCCCCCCCHHHHHHHHHCCCCCCCEEECCCEEEECCCCCCHHHHHHHHHHHHHHCCC
DSKAYVAPEGDQGFLDLLWTMVGGKASPVHAAGVQTPGGSGALRLAADLIRQAGTGRIWL
CCCEEECCCCCCHHHHHHHHHHCCCCCCCEECCCCCCCCCCHHHHHHHHHHHCCCCEEEE
GLPSWPNHAGIFAAAGLAIETYPYFDVPSQTLLLDGMLEALQRAQPGDAVLLHASCHNPT
ECCCCCCCCCHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCC
GAPLGAADWARITDVIATRGLVPLIDSAYQGFGAGFEGDVAGLRALVAAIPEALVAVSCS
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KSFGLYRERTGALFAVAGTTAAVETARSNLVAIARTSYSMPPDHGSAIVKTILGTPELYD
HHHCCHHHCCCCEEEEECCHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHCCCHHHH
DWRAELESMRQRLASLRRSFAEALGGRWSNSLAIGKQEGMFSLLPLTPAEVMTLREKHGV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCEEEECCCHHHHHHHHHHCCE
YMPTSGRINVAGLKLSDVTRVAGLFKAI
ECCCCCCEEEEEEEHHHHHHHHHHHHCC
>Mature Secondary Structure
MFERLSRQPDDPLLALIGIFKADPRTDKVDLGVGVYRDEAGHSPIFRAVKAAEQRIWASQ
CCCCCCCCCCCHHHHHHHHHCCCCCCCEEECCCEEEECCCCCCHHHHHHHHHHHHHHCCC
DSKAYVAPEGDQGFLDLLWTMVGGKASPVHAAGVQTPGGSGALRLAADLIRQAGTGRIWL
CCCEEECCCCCCHHHHHHHHHHCCCCCCCEECCCCCCCCCCHHHHHHHHHHHCCCCEEEE
GLPSWPNHAGIFAAAGLAIETYPYFDVPSQTLLLDGMLEALQRAQPGDAVLLHASCHNPT
ECCCCCCCCCHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCC
GAPLGAADWARITDVIATRGLVPLIDSAYQGFGAGFEGDVAGLRALVAAIPEALVAVSCS
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KSFGLYRERTGALFAVAGTTAAVETARSNLVAIARTSYSMPPDHGSAIVKTILGTPELYD
HHHCCHHHCCCCEEEEECCHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHCCCHHHH
DWRAELESMRQRLASLRRSFAEALGGRWSNSLAIGKQEGMFSLLPLTPAEVMTLREKHGV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCEEEECCCHHHHHHHHHHCCE
YMPTSGRINVAGLKLSDVTRVAGLFKAI
ECCCCCCEEEEEEEHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2019560; 8096210; 11481430 [H]