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The map label for this gene is atoS [C]

Identifier: 146340437

GI number: 146340437

Start: 3656660

End: 3658909

Strand: Reverse

Name: atoS [C]

Synonym: BRADO3477

Alternate gene names: 146340437

Gene position: 3658909-3656660 (Counterclockwise)

Preceding gene: 146340438

Following gene: 146340435

Centisome position: 49.07

GC content: 68.31

Gene sequence:

>2250_bases
ATGATCCGGCGGCGCGTGGCGATCGGCCTCGGACTTGGAACTCTGCTGGCGATGGGCGCGGCCTCCACGGCGCTGGACAT
CAAGGCGCGGAACGACGCGATCCTGGTCGAGCACACGCTCGAGGTTCTCGAGAAATCGTCAGAGCTGCGCCTGCTGCTCC
GCCAGGCCGAAGCGTCTTCACGCGGCTTTGCCTTGTCGGGCGCGGATCGGTTCGTCACCGAGTTCCAGGACAGCGGTCGC
AGAACTCCCGCGACATGGGCCGATCTCGTCGCGCTCGTGCAGGACAATCCGACGCAGAGCGCGCGGCTGCATGCGATTGA
CGAAGACGTGCAGCGGCGAATCGCGCTCTCGGGCGAGCTCATCCGCCGCCAGGCGGCCAACGACCGCGCCGGCGTCGCGT
CGCTCGTGGCGGGGGCGGCCGGCCCGACCGCGATGGCGACGATCAACGGGGTGCTCGACTCCTTCACCGAGGAAGAACGC
CGGCTGCTGAACGTGCGCACCGCGACCTCCCGGAGGACGGGAACATGGCTCTTGGCCATCGATCTCGCGGGCGTCGGCAT
CCTGATGCTGATCGCGGCCTATCTCGTCCGGCGCGCCTATCAGTCGGACCGCGCCCTGCGCCTTTCGCTCCGCCAGTCGC
AGGCGACGGCCACGTCTCTGGAGGCACAGGCACTGCAGCAGCGCGGCGATCTGGCGGCCGCCTATGACGAGCTGCGCCGC
TCCTCGGCCATTCTCGAAAACACGTTCAACAGCATGGCGGAGGGCGTTCTGGTGGTCGACCCCGCGGGCAAGTTCGTGCT
GTCGAACGAGGCCGCCGGACAGTTCTTCGGGCCCAGCGCGGGGAAGAGCTTCTCCGACATGCTGGTCACCAATCAGTTCC
ACGAGAACGATGCGGTGACCCGTATCCGCGACGAGGATCTGCCGATCGCGCGCGCCCTGCGCGGGCTCTCCTTCGATCGT
CGCGAGGTGGTGGTGAAGCCGACCGACGGCCGGCCACAGTTCCGGCTGATGGTCAGCGGTCGGCCGCTGCGCAACTCCGA
GGGCGCGATCAGCGGCGCGGCGCTGGTCTACCATGACGTGACCGAAGTGCACGAGATCGAGCGGCTGCTGCAGCAGGCGC
AGAAGCTCGATGCCATCGGCAAGCTGACCGGCGGCGTCGCGCACGACTTCAACAACATGCTCACGATCATCACCGGCTCG
ATCGAGATGCTGGTCGACACCGTCCGCGACCGGCCGGCCGCGGCCGAGCTCGCGGTGCTGATCAGCAGGGCAACGGACCG
CTGCACCGAGCTGATCCGTCATCTCCTCGCCTTTGCGCGCAAGCAGCCGCTGCGCCCGCGCGACATCGACGTCAACGCCA
CGGTCGAGGACATCGCCAAGCTGCTGCGGCCGACGCTCGGCGAGCAGGTGGAGATCAGGACCATTCTCGCCGAGGGCGAT
CTCGTCGCCCATGTCGATTCCGCCCAGCTTGCGAACGCGCTGGTCAATCTCGCCATCAACGCGCGCGACGCGATGCCGGA
GGGCGGCAAGCTGCTGCTGGAGACCGCGACGACGAGGCTCGACGAGTCCTATGCCGCGGCCAATCCCGGCGTCGTGCCGG
GTGCCTACGTCATGGTTGCCGTGAGCGACACCGGCACCGGCATGCCGGCGGGGGTCAAGGACCGCGCATTCGAGCCGTTC
TTCACCACCAAGGACGCGGGCAAGGGCTCGGGTCTCGGGCTCAGCATGGTGTATGGCTTCGTCAAGCAGTCAGGGGGCCA
CATCAAGCTTTACAGCGAGGAGAATCGCGGCACCACCATCCGGCTTTATCTGCCGGAGGCGCAGGTGCGGCGGCGGACGG
AGCCGGAGGCCGAGCAGGAGCTGCCGCGCGGCACGGAGACGATCCTCGTGGTGGAGGACGATCCGCTGGTGCGCGACTTC
GTGCTCGCCCAATTGCAGGGCCTCGGCTACGTCACCCTCGTCGCCTCGCAGGCCGCGGAGGCGTTGAGCATTGTCGCGCA
CGACCGGCCCTTCGATCTCTTGTTCACCGACGTGATCATGCCCGGCGGCGTCAGCGGCCGCCAGCTCGCGGAGACGATCA
TGGCGAGCCGCCCCGGACTCCGGGTACTCTACACCTCCGGCTACACCGACAACGCGATCATCGAGAACCGCCAGCTCGCG
CCCGACACGCTGCTGCTGACCAAACCCTATCGCCGCGCCGAGCTGGCGCAGATGGTGCGCCGCGCGCTCGATGGGCCGGC
CGGCGGTTGA

Upstream 100 bases:

>100_bases
GCAAGTCTGATCGAAACATCGACATGCGCGATTGAGAAGCATTCATAACCACGATGGTGTTTGAGCGACCAGGCGCACCT
GACGCGATTGGACCTTCACC

Downstream 100 bases:

>100_bases
TCTACTAGCCGCGTGTCGCGAGCGCCACCGCTCCGAGCGTGAAGGCGAGCGCGGCGATCTGCCCTGCCCCCAGCGGTTCG
CGCAGCGCGATCGCCGAGGC

Product: sensor histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 749; Mature: 749

Protein sequence:

>749_residues
MIRRRVAIGLGLGTLLAMGAASTALDIKARNDAILVEHTLEVLEKSSELRLLLRQAEASSRGFALSGADRFVTEFQDSGR
RTPATWADLVALVQDNPTQSARLHAIDEDVQRRIALSGELIRRQAANDRAGVASLVAGAAGPTAMATINGVLDSFTEEER
RLLNVRTATSRRTGTWLLAIDLAGVGILMLIAAYLVRRAYQSDRALRLSLRQSQATATSLEAQALQQRGDLAAAYDELRR
SSAILENTFNSMAEGVLVVDPAGKFVLSNEAAGQFFGPSAGKSFSDMLVTNQFHENDAVTRIRDEDLPIARALRGLSFDR
REVVVKPTDGRPQFRLMVSGRPLRNSEGAISGAALVYHDVTEVHEIERLLQQAQKLDAIGKLTGGVAHDFNNMLTIITGS
IEMLVDTVRDRPAAAELAVLISRATDRCTELIRHLLAFARKQPLRPRDIDVNATVEDIAKLLRPTLGEQVEIRTILAEGD
LVAHVDSAQLANALVNLAINARDAMPEGGKLLLETATTRLDESYAAANPGVVPGAYVMVAVSDTGTGMPAGVKDRAFEPF
FTTKDAGKGSGLGLSMVYGFVKQSGGHIKLYSEENRGTTIRLYLPEAQVRRRTEPEAEQELPRGTETILVVEDDPLVRDF
VLAQLQGLGYVTLVASQAAEALSIVAHDRPFDLLFTDVIMPGGVSGRQLAETIMASRPGLRVLYTSGYTDNAIIENRQLA
PDTLLLTKPYRRAELAQMVRRALDGPAGG

Sequences:

>Translated_749_residues
MIRRRVAIGLGLGTLLAMGAASTALDIKARNDAILVEHTLEVLEKSSELRLLLRQAEASSRGFALSGADRFVTEFQDSGR
RTPATWADLVALVQDNPTQSARLHAIDEDVQRRIALSGELIRRQAANDRAGVASLVAGAAGPTAMATINGVLDSFTEEER
RLLNVRTATSRRTGTWLLAIDLAGVGILMLIAAYLVRRAYQSDRALRLSLRQSQATATSLEAQALQQRGDLAAAYDELRR
SSAILENTFNSMAEGVLVVDPAGKFVLSNEAAGQFFGPSAGKSFSDMLVTNQFHENDAVTRIRDEDLPIARALRGLSFDR
REVVVKPTDGRPQFRLMVSGRPLRNSEGAISGAALVYHDVTEVHEIERLLQQAQKLDAIGKLTGGVAHDFNNMLTIITGS
IEMLVDTVRDRPAAAELAVLISRATDRCTELIRHLLAFARKQPLRPRDIDVNATVEDIAKLLRPTLGEQVEIRTILAEGD
LVAHVDSAQLANALVNLAINARDAMPEGGKLLLETATTRLDESYAAANPGVVPGAYVMVAVSDTGTGMPAGVKDRAFEPF
FTTKDAGKGSGLGLSMVYGFVKQSGGHIKLYSEENRGTTIRLYLPEAQVRRRTEPEAEQELPRGTETILVVEDDPLVRDF
VLAQLQGLGYVTLVASQAAEALSIVAHDRPFDLLFTDVIMPGGVSGRQLAETIMASRPGLRVLYTSGYTDNAIIENRQLA
PDTLLLTKPYRRAELAQMVRRALDGPAGG
>Mature_749_residues
MIRRRVAIGLGLGTLLAMGAASTALDIKARNDAILVEHTLEVLEKSSELRLLLRQAEASSRGFALSGADRFVTEFQDSGR
RTPATWADLVALVQDNPTQSARLHAIDEDVQRRIALSGELIRRQAANDRAGVASLVAGAAGPTAMATINGVLDSFTEEER
RLLNVRTATSRRTGTWLLAIDLAGVGILMLIAAYLVRRAYQSDRALRLSLRQSQATATSLEAQALQQRGDLAAAYDELRR
SSAILENTFNSMAEGVLVVDPAGKFVLSNEAAGQFFGPSAGKSFSDMLVTNQFHENDAVTRIRDEDLPIARALRGLSFDR
REVVVKPTDGRPQFRLMVSGRPLRNSEGAISGAALVYHDVTEVHEIERLLQQAQKLDAIGKLTGGVAHDFNNMLTIITGS
IEMLVDTVRDRPAAAELAVLISRATDRCTELIRHLLAFARKQPLRPRDIDVNATVEDIAKLLRPTLGEQVEIRTILAEGD
LVAHVDSAQLANALVNLAINARDAMPEGGKLLLETATTRLDESYAAANPGVVPGAYVMVAVSDTGTGMPAGVKDRAFEPF
FTTKDAGKGSGLGLSMVYGFVKQSGGHIKLYSEENRGTTIRLYLPEAQVRRRTEPEAEQELPRGTETILVVEDDPLVRDF
VLAQLQGLGYVTLVASQAAEALSIVAHDRPFDLLFTDVIMPGGVSGRQLAETIMASRPGLRVLYTSGYTDNAIIENRQLA
PDTLLLTKPYRRAELAQMVRRALDGPAGG

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=398, Percent_Identity=26.8844221105528, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1790436, Length=238, Percent_Identity=28.9915966386555, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1790300, Length=369, Percent_Identity=26.8292682926829, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI87081816, Length=218, Percent_Identity=24.3119266055046, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 81091; Mature: 81091

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRRRVAIGLGLGTLLAMGAASTALDIKARNDAILVEHTLEVLEKSSELRLLLRQAEASS
CCCCEEEECCCHHHHHHHCCCCCEEEEEECCCEEEHHHHHHHHHCCHHHHHHHHHHCCCC
RGFALSGADRFVTEFQDSGRRTPATWADLVALVQDNPTQSARLHAIDEDVQRRIALSGEL
CCEEECCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHH
IRRQAANDRAGVASLVAGAAGPTAMATINGVLDSFTEEERRLLNVRTATSRRTGTWLLAI
HHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHECCCCCCCCEEEEEE
DLAGVGILMLIAAYLVRRAYQSDRALRLSLRQSQATATSLEAQALQQRGDLAAAYDELRR
EHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
SSAILENTFNSMAEGVLVVDPAGKFVLSNEAAGQFFGPSAGKSFSDMLVTNQFHENDAVT
HHHHHHHHHHHHHCCEEEECCCCCEEECCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCE
RIRDEDLPIARALRGLSFDRREVVVKPTDGRPQFRLMVSGRPLRNSEGAISGAALVYHDV
EECCCCCCHHHHHHCCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCEEEHHHH
TEVHEIERLLQQAQKLDAIGKLTGGVAHDFNNMLTIITGSIEMLVDTVRDRPAAAELAVL
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCEEEEEECHHHHHHHHHHCCCHHHHHHHH
ISRATDRCTELIRHLLAFARKQPLRPRDIDVNATVEDIAKLLRPTLGEQVEIRTILAEGD
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEECCC
LVAHVDSAQLANALVNLAINARDAMPEGGKLLLETATTRLDESYAAANPGVVPGAYVMVA
EEEECCHHHHHHHHHHHHEECCCCCCCCCEEEEEHHHHHHHHHHHCCCCCCCCCCEEEEE
VSDTGTGMPAGVKDRAFEPFFTTKDAGKGSGLGLSMVYGFVKQSGGHIKLYSEENRGTTI
EECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCEE
RLYLPEAQVRRRTEPEAEQELPRGTETILVVEDDPLVRDFVLAQLQGLGYVTLVASQAAE
EEECCHHHHHHCCCCCHHHHCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEHHHHHHHH
ALSIVAHDRPFDLLFTDVIMPGGVSGRQLAETIMASRPGLRVLYTSGYTDNAIIENRQLA
HHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCEECCCCCC
PDTLLLTKPYRRAELAQMVRRALDGPAGG
CCEEEEECCHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MIRRRVAIGLGLGTLLAMGAASTALDIKARNDAILVEHTLEVLEKSSELRLLLRQAEASS
CCCCEEEECCCHHHHHHHCCCCCEEEEEECCCEEEHHHHHHHHHCCHHHHHHHHHHCCCC
RGFALSGADRFVTEFQDSGRRTPATWADLVALVQDNPTQSARLHAIDEDVQRRIALSGEL
CCEEECCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHH
IRRQAANDRAGVASLVAGAAGPTAMATINGVLDSFTEEERRLLNVRTATSRRTGTWLLAI
HHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHECCCCCCCCEEEEEE
DLAGVGILMLIAAYLVRRAYQSDRALRLSLRQSQATATSLEAQALQQRGDLAAAYDELRR
EHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
SSAILENTFNSMAEGVLVVDPAGKFVLSNEAAGQFFGPSAGKSFSDMLVTNQFHENDAVT
HHHHHHHHHHHHHCCEEEECCCCCEEECCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCE
RIRDEDLPIARALRGLSFDRREVVVKPTDGRPQFRLMVSGRPLRNSEGAISGAALVYHDV
EECCCCCCHHHHHHCCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCEEEHHHH
TEVHEIERLLQQAQKLDAIGKLTGGVAHDFNNMLTIITGSIEMLVDTVRDRPAAAELAVL
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCEEEEEECHHHHHHHHHHCCCHHHHHHHH
ISRATDRCTELIRHLLAFARKQPLRPRDIDVNATVEDIAKLLRPTLGEQVEIRTILAEGD
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEECCC
LVAHVDSAQLANALVNLAINARDAMPEGGKLLLETATTRLDESYAAANPGVVPGAYVMVA
EEEECCHHHHHHHHHHHHEECCCCCCCCCEEEEEHHHHHHHHHHHCCCCCCCCCCEEEEE
VSDTGTGMPAGVKDRAFEPFFTTKDAGKGSGLGLSMVYGFVKQSGGHIKLYSEENRGTTI
EECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCEE
RLYLPEAQVRRRTEPEAEQELPRGTETILVVEDDPLVRDFVLAQLQGLGYVTLVASQAAE
EEECCHHHHHHCCCCCHHHHCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEHHHHHHHH
ALSIVAHDRPFDLLFTDVIMPGGVSGRQLAETIMASRPGLRVLYTSGYTDNAIIENRQLA
HHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCEECCCCCC
PDTLLLTKPYRRAELAQMVRRALDGPAGG
CCEEEEECCHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA