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The map label for this gene is ucpA [C]

Identifier: 146340270

GI number: 146340270

Start: 3488229

End: 3489047

Strand: Direct

Name: ucpA [C]

Synonym: BRADO3291

Alternate gene names: 146340270

Gene position: 3488229-3489047 (Clockwise)

Preceding gene: 146340268

Following gene: 146340271

Centisome position: 46.78

GC content: 71.31

Gene sequence:

>819_bases
ATGACCAGTCCTCTCCTGCGGCCGTTGGCAGAGGCCGACCGCTTGCGCCGCGCCTATGGCGCCACTGCTGTCGTCACCGG
CGCCTCCGATGGGATCGGTCGCGCCGTGGCGATGCGCCTCGCGCAGGCCGGCTTCGGCCTCGTGCTGGTCGCGCGGCGCA
AGGCGGTGCTGGACGCACTCGCCGACGAGCTCGAAGCGCTGCAGTCGATCCGACCCGTCGTGATCTCGGCTGATCTTTCG
GTGCCAGACGATGTCGCGCGCATCGACCGCGACACCGCGCATCTCGATGTCGGCCTGCTGGTCGCCGCCGCCGGTTTCGG
CACCTCGGGCCCGTTCGTCGACGGCGATCTCACCGCCGAGCTCAACATGATCGACGTCAACTGCCGCGCGCTGGCGCAGC
TCACGCACATGTTCGGCCGCCGCTTCGCCGCGAGACGGCGCGGCGGCATCGTGCTGATGAGTTCGCTGGTCGCGTTCCAG
GGCGTGCCGCGGGCCGCCAACTATGCCGCGACGAAAGCGTTCGTGCAGAGCCTCGCCGAGGGCCTCGCGCCCGAGCTCAA
GCCGTTCGGCGTCGACGTCCTGGCCTCGGCGCCGGGGCCGGTGATGAGCGGCTTCGGCCAGCGCGCCCGCATGACGATTG
CGAGCGGCCAGACTCCCGACGAGGTCGCGGTCGGCACGCTCAAGATGCTGGGCCGCTGCACCACGGTGCGGCCCGGCTTT
CTCGCCAAGGCGCTGGAGGCCAGCCTGATGCTGCTGCCGCGCTCGGGCCGTGCCGCAATGCTGGCGCGGGTGATGGCCGG
CATGACGAAGACGGCGTGA

Upstream 100 bases:

>100_bases
TGCGCATCTGATCGAACCTGATGTGTTGGTCTTGACAATTTAGCGGTCGTCCGACATCTTTGCAATTAGAGTTCGATCAT
AATCTAAATTGGAGCCGTTC

Downstream 100 bases:

>100_bases
CTCCGCGACATTCTCTGCTGCGCGACGGAGCACGAGAGCCATGGCGAGGAGCCGGCAGAGGCCACCGTCACCATCCGTGA
CCGCCGGCTCACCGTGCAGC

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MTSPLLRPLAEADRLRRAYGATAVVTGASDGIGRAVAMRLAQAGFGLVLVARRKAVLDALADELEALQSIRPVVISADLS
VPDDVARIDRDTAHLDVGLLVAAAGFGTSGPFVDGDLTAELNMIDVNCRALAQLTHMFGRRFAARRRGGIVLMSSLVAFQ
GVPRAANYAATKAFVQSLAEGLAPELKPFGVDVLASAPGPVMSGFGQRARMTIASGQTPDEVAVGTLKMLGRCTTVRPGF
LAKALEASLMLLPRSGRAAMLARVMAGMTKTA

Sequences:

>Translated_272_residues
MTSPLLRPLAEADRLRRAYGATAVVTGASDGIGRAVAMRLAQAGFGLVLVARRKAVLDALADELEALQSIRPVVISADLS
VPDDVARIDRDTAHLDVGLLVAAAGFGTSGPFVDGDLTAELNMIDVNCRALAQLTHMFGRRFAARRRGGIVLMSSLVAFQ
GVPRAANYAATKAFVQSLAEGLAPELKPFGVDVLASAPGPVMSGFGQRARMTIASGQTPDEVAVGTLKMLGRCTTVRPGF
LAKALEASLMLLPRSGRAAMLARVMAGMTKTA
>Mature_271_residues
TSPLLRPLAEADRLRRAYGATAVVTGASDGIGRAVAMRLAQAGFGLVLVARRKAVLDALADELEALQSIRPVVISADLSV
PDDVARIDRDTAHLDVGLLVAAAGFGTSGPFVDGDLTAELNMIDVNCRALAQLTHMFGRRFAARRRGGIVLMSSLVAFQG
VPRAANYAATKAFVQSLAEGLAPELKPFGVDVLASAPGPVMSGFGQRARMTIASGQTPDEVAVGTLKMLGRCTTVRPGFL
AKALEASLMLLPRSGRAAMLARVMAGMTKTA

Specific function: Unknown

COG id: COG0300

COG function: function code R; Short-chain dehydrogenases of various substrate specificities

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7705855, Length=259, Percent_Identity=28.957528957529, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI4557649, Length=217, Percent_Identity=28.110599078341, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI226371731, Length=245, Percent_Identity=28.1632653061224, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI20149619, Length=238, Percent_Identity=27.3109243697479, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI4503817, Length=220, Percent_Identity=30, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI7657478, Length=205, Percent_Identity=29.2682926829268, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87082100, Length=207, Percent_Identity=31.4009661835749, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1789208, Length=204, Percent_Identity=28.4313725490196, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI25152911, Length=273, Percent_Identity=30.03663003663, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17560176, Length=249, Percent_Identity=25.3012048192771, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71994604, Length=226, Percent_Identity=29.646017699115, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17559552, Length=249, Percent_Identity=24.8995983935743, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI115534694, Length=243, Percent_Identity=30.4526748971193, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562906, Length=206, Percent_Identity=30.5825242718447, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6319635, Length=243, Percent_Identity=27.5720164609054, Blast_Score=82, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6322067, Length=192, Percent_Identity=32.2916666666667, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24584752, Length=205, Percent_Identity=32.6829268292683, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24584744, Length=189, Percent_Identity=33.8624338624339, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28574402, Length=189, Percent_Identity=33.8624338624339, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI161076933, Length=279, Percent_Identity=29.3906810035842, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24584748, Length=262, Percent_Identity=30.1526717557252, Blast_Score=94, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24640442, Length=232, Percent_Identity=30.6034482758621, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI28571526, Length=190, Percent_Identity=32.6315789473684, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24580925, Length=201, Percent_Identity=30.3482587064677, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21357041, Length=187, Percent_Identity=30.4812834224599, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21358495, Length=275, Percent_Identity=24.7272727272727, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24644339, Length=196, Percent_Identity=29.5918367346939, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI21355319, Length=228, Percent_Identity=25.8771929824561, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 28371; Mature: 28239

Theoretical pI: Translated: 10.77; Mature: 10.77

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPLLRPLAEADRLRRAYGATAVVTGASDGIGRAVAMRLAQAGFGLVLVARRKAVLDAL
CCCHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHH
ADELEALQSIRPVVISADLSVPDDVARIDRDTAHLDVGLLVAAAGFGTSGPFVDGDLTAE
HHHHHHHHHCCCEEEEECCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEE
LNMIDVNCRALAQLTHMFGRRFAARRRGGIVLMSSLVAFQGVPRAANYAATKAFVQSLAE
EEEEECCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
GLAPELKPFGVDVLASAPGPVMSGFGQRARMTIASGQTPDEVAVGTLKMLGRCTTVRPGF
HCCCCCCCCCCEEECCCCCHHHHCCCCHHEEEEECCCCCHHHHHHHHHHHHHHCCCCCHH
LAKALEASLMLLPRSGRAAMLARVMAGMTKTA
HHHHHHHHHEEECCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TSPLLRPLAEADRLRRAYGATAVVTGASDGIGRAVAMRLAQAGFGLVLVARRKAVLDAL
CCHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHH
ADELEALQSIRPVVISADLSVPDDVARIDRDTAHLDVGLLVAAAGFGTSGPFVDGDLTAE
HHHHHHHHHCCCEEEEECCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEE
LNMIDVNCRALAQLTHMFGRRFAARRRGGIVLMSSLVAFQGVPRAANYAATKAFVQSLAE
EEEEECCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
GLAPELKPFGVDVLASAPGPVMSGFGQRARMTIASGQTPDEVAVGTLKMLGRCTTVRPGF
HCCCCCCCCCCEEECCCCCHHHHCCCCHHEEEEECCCCCHHHHHHHHHHHHHHCCCCCHH
LAKALEASLMLLPRSGRAAMLARVMAGMTKTA
HHHHHHHHHEEECCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12950922 [H]