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The map label for this gene is lon [H]

Identifier: 146340102

GI number: 146340102

Start: 3309010

End: 3310239

Strand: Reverse

Name: lon [H]

Synonym: BRADO3111

Alternate gene names: 146340102

Gene position: 3310239-3309010 (Counterclockwise)

Preceding gene: 146340104

Following gene: 146340095

Centisome position: 44.39

GC content: 68.78

Gene sequence:

>1230_bases
ATGCGCGATTTTCGCGATGCCAAGGTCATGGCACAGACACTGCGCGAGTGCCTGACCACCCAATCCATCACCATCAGCCA
TAGCCACAGCCTGGAGCTGGTCTCACGGATGTTCGGCCTGGCCGACTGGAACACACTGTCCGCGCTGATCAAGGCCGCTG
ACGGCGCCAAGCTGACGCGGCCGCCGGTCATTCAGGCCGAGATACAGCGGCGTCCGGCCCTTCCGCTGCGCGACTTCGTC
CCGTTTCCAGGCGCCACCCACCCGCTGTTCGTCGGGCGCGCCAAGACGATCAATGCGCTCAACGACGCCTTTACGAAACA
GAGCGATGTCGTGATCGCGCTGCAGAAGCAGCAAGCGGTGGACGAGCCCAGCCTGGCTGATCTGCATGAGATCGGGCTGC
GCGCCGACCTGATCGAGCTCACGCCGCTGCCCGACGGCACGCTGAAGGTGCAGGTCCGCATCATCAGGCGCGTCCGGGTC
AGGGCGTTCAGCAGCGACGCCAGCGCCTACCAAGCCGAAATCTCCGACATCAGCGAGGACAGCGCGGCCGATGCGCCGGA
TCTCATCCTGCGCGCCGTCACGCGCTTCGAGCGCTACGCCGCGATCCGCAACATCCGCCTGCCCGACGGCTGGCCGCCGT
TCGGCGAGGGCCGCCACCCCGGCCGCGTCGCCGACCTCATCGCCGCGCTGGTGCTGCTGCCGCTCGCGCACAAATACGAG
CTGCTGGCGGTGCTCGATCCGGTCAAGCGCCTGGAGCTGGTCGAGACGCTGCTCGATGTGACGGCGCGACCGCTGTCGTC
GGCGCTGCAGGCGACACGGCAGCGTGCGATCGCAAACGCGCGCGACCGCCGGCATCGCCATGCCACGCTCGAGCATCTGC
TGCTGGCGTTGCTCGACGACGACAGCGCCGCAGCCGTGATGCGAAGCTGCCGCGCGAGCCTGGCGCAGTTGCGGACCAAG
ACACGGCTTTATGTGGACACGGAGCTCAGCCATCTCGCCACCGAGGATGACGACATCGCGCAGCCGACCGATGCGTTCCG
ACGCGTCAACGACCGCGCCGCGCTCGCCGCCCAGGAGGTCGGCTACCCGCTCGTCACCGGCGCCAACACGCTGCTCGCGC
TGTTCCCGGAAACCCGCAGCCCGGCCGCACGCCTGCTCGCCGAGCACGGCGTGACCATGGTGCGGGCCGCCAAGGCGGTG
GCCGACGGCGTGGGCAAGGAGGAGGCCTGA

Upstream 100 bases:

>100_bases
GAACGTATCGAGCCTTCTTGGCCTCCCCCTTTGCCCGAGCGACCGGGTCAGCAACGCAGCCACCTGACATGCCTGGTTCG
CTCCTGCAGAGGATCAAGCG

Downstream 100 bases:

>100_bases
GCGGGGGCTTGCACTTCGTAGCCCGGATGAGCGCAGCGACATCCGGGGTCACACGCGCTTTCGCGACGAACCCGGATATC
GCTGCGCTCATCCGGGCTAC

Product: putative ATP-dependent protease La

Products: NA

Alternate protein names: ATP-dependent protease La [H]

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MRDFRDAKVMAQTLRECLTTQSITISHSHSLELVSRMFGLADWNTLSALIKAADGAKLTRPPVIQAEIQRRPALPLRDFV
PFPGATHPLFVGRAKTINALNDAFTKQSDVVIALQKQQAVDEPSLADLHEIGLRADLIELTPLPDGTLKVQVRIIRRVRV
RAFSSDASAYQAEISDISEDSAADAPDLILRAVTRFERYAAIRNIRLPDGWPPFGEGRHPGRVADLIAALVLLPLAHKYE
LLAVLDPVKRLELVETLLDVTARPLSSALQATRQRAIANARDRRHRHATLEHLLLALLDDDSAAAVMRSCRASLAQLRTK
TRLYVDTELSHLATEDDDIAQPTDAFRRVNDRAALAAQEVGYPLVTGANTLLALFPETRSPAARLLAEHGVTMVRAAKAV
ADGVGKEEA

Sequences:

>Translated_409_residues
MRDFRDAKVMAQTLRECLTTQSITISHSHSLELVSRMFGLADWNTLSALIKAADGAKLTRPPVIQAEIQRRPALPLRDFV
PFPGATHPLFVGRAKTINALNDAFTKQSDVVIALQKQQAVDEPSLADLHEIGLRADLIELTPLPDGTLKVQVRIIRRVRV
RAFSSDASAYQAEISDISEDSAADAPDLILRAVTRFERYAAIRNIRLPDGWPPFGEGRHPGRVADLIAALVLLPLAHKYE
LLAVLDPVKRLELVETLLDVTARPLSSALQATRQRAIANARDRRHRHATLEHLLLALLDDDSAAAVMRSCRASLAQLRTK
TRLYVDTELSHLATEDDDIAQPTDAFRRVNDRAALAAQEVGYPLVTGANTLLALFPETRSPAARLLAEHGVTMVRAAKAV
ADGVGKEEA
>Mature_409_residues
MRDFRDAKVMAQTLRECLTTQSITISHSHSLELVSRMFGLADWNTLSALIKAADGAKLTRPPVIQAEIQRRPALPLRDFV
PFPGATHPLFVGRAKTINALNDAFTKQSDVVIALQKQQAVDEPSLADLHEIGLRADLIELTPLPDGTLKVQVRIIRRVRV
RAFSSDASAYQAEISDISEDSAADAPDLILRAVTRFERYAAIRNIRLPDGWPPFGEGRHPGRVADLIAALVLLPLAHKYE
LLAVLDPVKRLELVETLLDVTARPLSSALQATRQRAIANARDRRHRHATLEHLLLALLDDDSAAAVMRSCRASLAQLRTK
TRLYVDTELSHLATEDDDIAQPTDAFRRVNDRAALAAQEVGYPLVTGANTLLALFPETRSPAARLLAEHGVTMVRAAKAV
ADGVGKEEA

Specific function: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced

COG id: COG0466

COG function: function code O; ATP-dependent Lon protease, bacterial type

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Lon domain [H]

Homologues:

Organism=Escherichia coli, GI1786643, Length=191, Percent_Identity=33.5078534031414, Blast_Score=105, Evalue=8e-24,
Organism=Escherichia coli, GI1787109, Length=145, Percent_Identity=37.9310344827586, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR008269
- InterPro:   IPR004815
- InterPro:   IPR003111
- InterPro:   IPR008268
- InterPro:   IPR001984
- InterPro:   IPR015947
- InterPro:   IPR020568 [H]

Pfam domain/function: PF00004 AAA; PF02190 LON; PF05362 Lon_C [H]

EC number: =3.4.21.53 [H]

Molecular weight: Translated: 44887; Mature: 44887

Theoretical pI: Translated: 7.81; Mature: 7.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDFRDAKVMAQTLRECLTTQSITISHSHSLELVSRMFGLADWNTLSALIKAADGAKLTR
CCCHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCC
PPVIQAEIQRRPALPLRDFVPFPGATHPLFVGRAKTINALNDAFTKQSDVVIALQKQQAV
CCCHHHHHHCCCCCCHHHCCCCCCCCCCEEECCHHHHHHHHHHHCCCCCEEEEEEHHHCC
DEPSLADLHEIGLRADLIELTPLPDGTLKVQVRIIRRVRVRAFSSDASAYQAEISDISED
CCCCHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCC
SAADAPDLILRAVTRFERYAAIRNIRLPDGWPPFGEGRHPGRVADLIAALVLLPLAHKYE
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LLAVLDPVKRLELVETLLDVTARPLSSALQATRQRAIANARDRRHRHATLEHLLLALLDD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DSAAAVMRSCRASLAQLRTKTRLYVDTELSHLATEDDDIAQPTDAFRRVNDRAALAAQEV
CHHHHHHHHHHHHHHHHHHHHEEEEECHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHC
GYPLVTGANTLLALFPETRSPAARLLAEHGVTMVRAAKAVADGVGKEEA
CCCEEECCCCEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRDFRDAKVMAQTLRECLTTQSITISHSHSLELVSRMFGLADWNTLSALIKAADGAKLTR
CCCHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCC
PPVIQAEIQRRPALPLRDFVPFPGATHPLFVGRAKTINALNDAFTKQSDVVIALQKQQAV
CCCHHHHHHCCCCCCHHHCCCCCCCCCCEEECCHHHHHHHHHHHCCCCCEEEEEEHHHCC
DEPSLADLHEIGLRADLIELTPLPDGTLKVQVRIIRRVRVRAFSSDASAYQAEISDISED
CCCCHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCC
SAADAPDLILRAVTRFERYAAIRNIRLPDGWPPFGEGRHPGRVADLIAALVLLPLAHKYE
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LLAVLDPVKRLELVETLLDVTARPLSSALQATRQRAIANARDRRHRHATLEHLLLALLDD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DSAAAVMRSCRASLAQLRTKTRLYVDTELSHLATEDDDIAQPTDAFRRVNDRAALAAQEV
CHHHHHHHHHHHHHHHHHHHHEEEEECHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHC
GYPLVTGANTLLALFPETRSPAARLLAEHGVTMVRAAKAVADGVGKEEA
CCCEEECCCCEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8666236 [H]