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The map label for this gene is hipO [H]

Identifier: 146339818

GI number: 146339818

Start: 3021096

End: 3022268

Strand: Reverse

Name: hipO [H]

Synonym: BRADO2819

Alternate gene names: 146339818

Gene position: 3022268-3021096 (Counterclockwise)

Preceding gene: 146339819

Following gene: 146339817

Centisome position: 40.53

GC content: 66.84

Gene sequence:

>1173_bases
ATGCCCATCATCAACAGCATCGCCGCCCTGTCAGACGAAATGGCGGCCTGGCGCCACGATTTCCACGAACATCCCGAGCT
TCTCTATGAGGTGCACCGCACGGCAGGCATCGTCGCCGACCGCTTGCGCGAATTCGGCTGTGACGAGGTCGTGACCGGCA
TTGGCCGCACGGGCGTGGTCGGCGTGATCCGCGGGCGCAAATCCGGCTCCGGCAAGACCATCGGGCTGCGCGCCGACATG
GACGCGCTGCCGATCGAGGAGACCTCGGGCGTGCCCTACGCGTCGAAGACGCCGGGCCTGATGCATGCCTGCGGCCATGA
CGGCCACACCGCGATGCTGCTGGGTGCCGCGAAGTACCTCGCCGAGACGCGCAATTTCGACGGCACCGCGATCGTCATCT
TCCAGCCGGCCGAGGAAGGCGGCGCCGGCGGCAAGGCGATGGTCGACGACGGGCTGATGACGCGCTGGGGCATCCAGGAG
GTCTATGGCATGCACAACATGCCGGGCGTTCCCGAGGGCCATTTCCAGATCTCGCCGGGCGCGATGCTCGCATCCGCCGA
TGCGATCCACATCAAGGTCACCGGCAAGGGCGGCCATGGCGGCGCCGGCCCGCACAAGGCGGTCGACAGCATCCTGATCG
CCGCGCAGATCGTCAACGCGCTGCAGTCGATCGTCGCCCGCAACGTCGATCCCTTGAAGTCGGCCGTCATCTCGATCTGC
TCGATCCATGGCGGCACCACCTTCAACGTGATCCCCGAGACGGTAGAGATGCTCGGCACCGTCCGCACACTCGATCCCGA
GGTCCGCGATCTCGTCGAGAAGCGCATCGTCGAAGTCGCCGAAGCCACCGCCCGCGCCTATGGCGGCTCGGCGGAAGCGA
TCTACGAGCGGAAATATCCAGTGACGATGAACCACGCGGCGCAGGCCGCCTTCGCCGCCGACGTTGCTCGCGATGTCGCC
GGTGACGAGCGCGTCAACGACCGTGCCATTCCCCTGATGGGCGGCGAAGACTTCGCCTTCATGCTCGAAGCCCGCCCCGG
CGCCTTCGTCTTCCTCGGCATGGGCCCCGGCAACGAGTGCCACCACCCGGCCTACCGCTTCAACGACAACATCCTCAGCG
CCGGCGCCTCCTACTGGGTCAAGCTGGTCGAGAAGAGCATGCCGGCGAGCTGA

Upstream 100 bases:

>100_bases
TTTTGGGCCGGGTCATAGTCGGTCATCGCAGCGGTGCTGCCGGCCGATATGGCCGCACGCTGCAGCGTCCCACCCCACCT
CAGCGAGTCGTCCGGTCCTC

Downstream 100 bases:

>100_bases
TCCGTTGATGAAAGCGTAGGGTGGGCGAGACAGCACGGCAGCGCCTTTGCCCACCCTACGGACTCGCGATCGTGGCTGGC
AGCGAACGTGCACCAAGCTC

Product: putative hippurate hydrolase

Products: NA

Alternate protein names: Benzoylglycine amidohydrolase; Hippuricase [H]

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MPIINSIAALSDEMAAWRHDFHEHPELLYEVHRTAGIVADRLREFGCDEVVTGIGRTGVVGVIRGRKSGSGKTIGLRADM
DALPIEETSGVPYASKTPGLMHACGHDGHTAMLLGAAKYLAETRNFDGTAIVIFQPAEEGGAGGKAMVDDGLMTRWGIQE
VYGMHNMPGVPEGHFQISPGAMLASADAIHIKVTGKGGHGGAGPHKAVDSILIAAQIVNALQSIVARNVDPLKSAVISIC
SIHGGTTFNVIPETVEMLGTVRTLDPEVRDLVEKRIVEVAEATARAYGGSAEAIYERKYPVTMNHAAQAAFAADVARDVA
GDERVNDRAIPLMGGEDFAFMLEARPGAFVFLGMGPGNECHHPAYRFNDNILSAGASYWVKLVEKSMPAS

Sequences:

>Translated_390_residues
MPIINSIAALSDEMAAWRHDFHEHPELLYEVHRTAGIVADRLREFGCDEVVTGIGRTGVVGVIRGRKSGSGKTIGLRADM
DALPIEETSGVPYASKTPGLMHACGHDGHTAMLLGAAKYLAETRNFDGTAIVIFQPAEEGGAGGKAMVDDGLMTRWGIQE
VYGMHNMPGVPEGHFQISPGAMLASADAIHIKVTGKGGHGGAGPHKAVDSILIAAQIVNALQSIVARNVDPLKSAVISIC
SIHGGTTFNVIPETVEMLGTVRTLDPEVRDLVEKRIVEVAEATARAYGGSAEAIYERKYPVTMNHAAQAAFAADVARDVA
GDERVNDRAIPLMGGEDFAFMLEARPGAFVFLGMGPGNECHHPAYRFNDNILSAGASYWVKLVEKSMPAS
>Mature_389_residues
PIINSIAALSDEMAAWRHDFHEHPELLYEVHRTAGIVADRLREFGCDEVVTGIGRTGVVGVIRGRKSGSGKTIGLRADMD
ALPIEETSGVPYASKTPGLMHACGHDGHTAMLLGAAKYLAETRNFDGTAIVIFQPAEEGGAGGKAMVDDGLMTRWGIQEV
YGMHNMPGVPEGHFQISPGAMLASADAIHIKVTGKGGHGGAGPHKAVDSILIAAQIVNALQSIVARNVDPLKSAVISICS
IHGGTTFNVIPETVEMLGTVRTLDPEVRDLVEKRIVEVAEATARAYGGSAEAIYERKYPVTMNHAAQAAFAADVARDVAG
DERVNDRAIPLMGGEDFAFMLEARPGAFVFLGMGPGNECHHPAYRFNDNILSAGASYWVKLVEKSMPAS

Specific function: Required But Not Essential For Aminobenzoyl-Glutamate Utilization. May Participate In Hydrolysis Of Aminobenzoyl- Glutamate To Aminobenzoate, Either Alone Or In Combination With Abgb. [C]

COG id: COG1473

COG function: function code R; Metal-dependent amidase/aminoacylase/carboxypeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20 family [H]

Homologues:

Organism=Escherichia coli, GI87081880, Length=417, Percent_Identity=27.0983213429257, Blast_Score=96, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017439
- InterPro:   IPR010168
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.32 [H]

Molecular weight: Translated: 41404; Mature: 41272

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIINSIAALSDEMAAWRHDFHEHPELLYEVHRTAGIVADRLREFGCDEVVTGIGRTGVV
CCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCEE
GVIRGRKSGSGKTIGLRADMDALPIEETSGVPYASKTPGLMHACGHDGHTAMLLGAAKYL
EEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHH
AETRNFDGTAIVIFQPAEEGGAGGKAMVDDGLMTRWGIQEVYGMHNMPGVPEGHFQISPG
HHHCCCCCEEEEEEECCCCCCCCCCEEECCCCHHHHHHHHHHCCCCCCCCCCCCEEECCC
AMLASADAIHIKVTGKGGHGGAGPHKAVDSILIAAQIVNALQSIVARNVDPLKSAVISIC
CEEECCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
SIHGGTTFNVIPETVEMLGTVRTLDPEVRDLVEKRIVEVAEATARAYGGSAEAIYERKYP
HCCCCCEEEECHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCC
VTMNHAAQAAFAADVARDVAGDERVNDRAIPLMGGEDFAFMLEARPGAFVFLGMGPGNEC
EEHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEEECCCCEEEEEECCCCCCC
HHPAYRFNDNILSAGASYWVKLVEKSMPAS
CCCCHHCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PIINSIAALSDEMAAWRHDFHEHPELLYEVHRTAGIVADRLREFGCDEVVTGIGRTGVV
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCEE
GVIRGRKSGSGKTIGLRADMDALPIEETSGVPYASKTPGLMHACGHDGHTAMLLGAAKYL
EEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHH
AETRNFDGTAIVIFQPAEEGGAGGKAMVDDGLMTRWGIQEVYGMHNMPGVPEGHFQISPG
HHHCCCCCEEEEEEECCCCCCCCCCEEECCCCHHHHHHHHHHCCCCCCCCCCCCEEECCC
AMLASADAIHIKVTGKGGHGGAGPHKAVDSILIAAQIVNALQSIVARNVDPLKSAVISIC
CEEECCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
SIHGGTTFNVIPETVEMLGTVRTLDPEVRDLVEKRIVEVAEATARAYGGSAEAIYERKYP
HCCCCCEEEECHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCC
VTMNHAAQAAFAADVARDVAGDERVNDRAIPLMGGEDFAFMLEARPGAFVFLGMGPGNEC
EEHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEEECCCCEEEEEECCCCCCC
HHPAYRFNDNILSAGASYWVKLVEKSMPAS
CCCCHHCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7730270; 10688204 [H]